author = { Castiglione, Monica Piccart-Gebhart, Martine J. },

title = { Adjuvant Therapy for Breast Cancer },

publisher = {Springer-Verlag US},

isbn = {9780387751153},

isbn = {9780387751146},

keywords = { Medicine , Oncology , Cancer Surgery , Medicine & Public Health , Breast Neoplasms therapy , Adjuvants, Pharmaceutic , Chemotherapy, Adjuvant , Radiotherapy, Adjuvant },

year = {2009},

abstract = {Includes bibliographical references and index},

abstract = {Adjuvant Therapy for Breast Cancer; Cancer Treatment and Research; Acknowledgments; Contents; Contributors; Introduction; Part 1: Basics; History of Adjuvant Therapy; The Guiding Principles of Adjuvant Therapy; Trials with Endocrine Therapy; Trials of Chemoendocrine Therapy; Trials with Chemotherapy; Concluding Remarks; References; Prognostic and Predictive Factors; Prognostic Factors; Age; Tumor Size; Axillary Nodes; Tumor Grade; HER2/neu Status; Peritumoral Vascular Invasion; Others; Predictive Factors; Predictive Markers for Adjuvant Hormonal Therapy},

abstract = {Predictive Markers for Adjuvant ChemotherapyHER-2 as a Predictive Marker; Topoisomerase II Alpha (Topo IIalpha); Markers Predicting the Activity of Taxane-Based Regimens; Markers Predicting the Activity of Anti-HER-2 Therapies; Conclusions; References; New Perspectives for Therapy Choice; Introduction; ''Omics'' in Cancer Diagnosis and Prognosis; Gene Expression Profiling: Genomics and Transcriptomics; Protein Profiling: Proteomics; Profiling of Metabolic Endproducts: Metabolomics; Nano-Particles in Diagnosis and Therapy; Perspectives; References; Pathology Role in Adjuvant Setting},

abstract = {IntroductionExamination of Pathology Specimens; Core Needle Biopsy - Preoperative Diagnosis; Surgical Specimens; Frozen Sections; Tissue Banks; Tumor Classification; Histopathologic Prognostic Factors; Tumor and Axillary Lymph Node Staging; Lymph and Blood Vessel Invasion; Tumor Size; Tumor Grading; Immunhistochemical Assays; Steroid Hormone Receptors; HER-2/neu; HER-2 Immunohistochemistry; HER-2 FISH; Interpretation and Scoring; Immunohistochemistry; FISH; Which Score to Be Used?; Future Aspects; Microarray Technology; References},

abstract = {Guidelines, Consensus Conferences and Overviews (Meta-analysis)Introduction; Meta-analysis or Overviews; Consensus Meetings and Documents; Clinical Practice Guidelines; Summary; References; Statistical Issues and Challenges; Learning from the Past; Planning for the Future; References; Part 2: Treatments; Multidisciplinary Care: Optimising Team Performance; Introduction; Sharing Goals and Strategies; Effective Team Meetings; Troubleshooting; Development and Coaching; Inspirational Leadership; Strengthening Commitment; Managing Conflict and Poor Performance; Preventing Burnout},

abstract = {Improving Communication with PatientsConclusions; References; Preoperative Chemo- and Endocrine Therapy; Primary Systemic Therapy: Rationale and State of the Art; The Role pf pCR; Anthracyclines and Taxanes: Which is the Gold Standard?; Primary Treatment of Endocrine Responsive Tumours; Open Issues; Identifying Powerful Predictors of Response; Beyond pCR; Integrating Targeted Agents; Conclusions; References; Adjuvant Chemotherapy; Anthracyclines in Adjuvant Therapy; Duration of treatment; Dose Intensity},

abstract = {Randomized Studies of High-Dose Adjuvant Chemotherapy with Hematopoietic Stem Cell Transplantation},

booktitle = {Cancer Treatment and Research ; 151},

booktitle = {SpringerLink ; Bücher},

address = { Boston, MA },

url = { http://slubdd.de/katalog?TN_libero_mab2 }