author = { Gautier, Jean-Charles },

title = { Drug safety evaluation },

edition = { Second Edition } ,

publisher = {Humana Press},

publisher = {},

isbn = {9781493971701},

isbn = {1493971700},

keywords = { Drugs Toxicology Laboratory manuals , Drugs Testing Laboratory manuals , Drug Evaluation, Preclinical methods , Drug-Related Side Effects and Adverse Reactions , Toxicity Tests methods , Laboratory Manuals , Arzneimittelsicherheit },

year = {[2017]},

abstract = {Nonclinical development of combination drugs Alberto Lodola},

abstract = {Juvenile nonclinical safety studies in support of pediatric drug development Paul C. Barrow and Georg Schmitt},

abstract = {Procedures of necropsy and tissue sampling Laurence Fiette, Mohamed Slaoui, and Anne-Laure Bauchet},

abstract = {Tissue sampling and processing for histopathology evaluation Mohamed Slaoui, Anne-Laure Bauchet, and Laurence Fiette},

abstract = {Principles and methods of immunohistochemistry José A. Ramos-Vara},

abstract = {Applications of mass spectrometry imaging for safety evaluation David Bonnel and Jonathan Stauber Part III Genetic Toxicology},

abstract = {In vivo rat T-lymphocyte Pig-a assay : detection and expansion of cells deficient in the GPI-anchored CD48 surface marker for analysis of mutation in the endogenous Pig-a gene Vasily N. Dobrovolsky, Javier Revollo, Dayton M. Petibone, and Robert H. Heflich},

abstract = {Detection of in vivo mutation in the Pig-a gene of mouse bone marrow erythroids Takafumi Kimoto and Daishiro Miura},

abstract = {Use of bacterial repair endonucleases in the comet assay Andrew R. Collins},

abstract = {Automated patch-clamp methods for the hERG cardiac potassium channel Sylvie Houtmann, Brigitte Schombert, Camille Sanson, Michel Partiseti, and G. Andrees Bohme},

abstract = {Impedance measurement in induced pluripotent stem cell-derived cardiomyocytes Emma-Jane Poulton},

abstract = {Target safety assessment : strategies and resources Richard J. Brennan},

abstract = {NMR and MS methods for metabolomics Alexander Amberg, Björn Riefke, Götz Schlotterbeck, Alfred Ross, Hans Senn, Frank Dieterle, and Matthias Keck},

abstract = {Protocols and applications of cellular metabolomics in safety studies using precision-cut tissue slices and carbon 13 NMR Gabriel Baverel, Maha El Hage, and Guy Martin},

abstract = {Statistical analysis of auantitative RT-PCR results Richard Khan-Malek and Ying Wang},

abstract = {Evaluation of mitochondrial respiration in cultured rat hepatocytes Jean-Pierre Marchandeau and Gilles Labbe},

abstract = {FETAX assay for evaluation of developmental toxicity Isabelle Mouche, Laure Malésic, and Olivier Gillardeaux},

abstract = {Evaluation of embryotoxicity using the Zebrafish model Lisa Truong and Robert L. Tanguay},

abstract = {Absolute quantification of toxicological biomarkers via mass spectrometry Thomas Y. K. Lau, Ben C. Collins, Peter Stone, Ning Tang, William M. Gallagher, and Stephen R. Pennington},

abstract = {Next-generation sequencing to investigate urinary microRNAs from Macaca fascicularis (cynomolgus monkey) Yaligara Veeranagouda, Jean-François Léonard, Jean-Charles Gautier, and Eric Boitier},

abstract = {Quantitative RT-PCR for microRNAs in biofluids Michael Thorsen, Thorarinn Blondal, and Peter Mouritzen},

abstract = {Chromogenic in situ hybridization methods for microRNA biomarker monitoring of drug safety and efficacy Barbara R. Gould, Tina Damgaard, and Boye Schnack Nielsen},

abstract = {Urine exosome isolation and characterization Jonathan M. Street, Erik H. Koritzinsky, Deonna M. Glispie, and Peter S.T. Yuen.},

booktitle = {Methods in molecular biology ; 1641},

address = { New York, NJ , },

url = { http://slubdd.de/katalog?TN_libero_mab2 }