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Okonechnikov, Konstantin; Sepp, Mari; Leiss, Kevin; Kutscher, Lena; Ernst, Kati; Jones, David; Jäger, Natalie; Pajtler, Kristian W; Kaessmann, Henrik; Pfister, Stefan M

MBRS-03. SINGLE NUCLEUS TRANSCRIPTOME PROFILES FROM HUMAN DEVELOPING CEREBELLUM REVEAL POTENTIAL CELLULAR ORIGINS OF MEDULLOBLASTOMA BRAIN TUMORS

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Oxford University Press (OUP), 2020

Published in: Neuro-Oncology
Vouri, Mikaela; Mercier, Audrey; da Silva, Patricia Benites Goncalves; Okonechnikov, Konstantin; Forget, Antoine; Yu, Hua; Chivet, Anais; Kool, Marcel; Pfister, Stefan; Ayrault, Olivier; Kawauchi, Daisuke

MBRS-51. MUTATIONS IN BRPF1 FOUND IN SHH MEDULLOBLASTOMA PREVENT INTERACTION WITH TP53 AND LEADS TO RADIORESISTANCE IN VITRO

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Oxford University Press (OUP), 2020

Published in: Neuro-Oncology
Okonechnikov, Konstantin; Hübner, Jens-Martin; Kraft, Katerina; Hidalgo, Rocio Acuna; Bump, Rosalind; Chandran, Sahaana; Mundlos, Stefan; Mesirov, Jill; Pajtler, Kristian; Dixon, Jesse; Pfister, Stefan; Kool, Marcel; Chavez, Lukas

GENE-02. CHROMOSOME CONFORMATION ANALYSIS OF EPENDYMOMA IDENTIFIES PUTATIVE TUMOR DEPENDENCY GENES ACTIVATED BY DISTAL ONCOGENIC ENHANCERS

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Oxford University Press (OUP), 2019

Published in: Neuro-Oncology
Pajtler, Kristian W.; Okonechnikov, Konstantin; Vouri, Mikaella; Brabetz, Sebastian; Jones, David T.; Korshunov, Andrey; Capper, David; Chavez, Lukas; Pfister, Stefan M.; Kool, Marcel; Kawauchi, Daisuke

Abstract 4124: YAP1 fusion proteins mediate oncogenic activity in ependymoma via interaction with TEAD transcription factors

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American Association for Cancer Research (AACR), 2018

Published in: Cancer Research
Hübner, Jens-Martin; Okonechnikov, Konstantin; Wen, Ji; Orisme, Wilda; Tang, Bo; Jia, Sujuan; Tatevossian, Ruth; Zhang, Jinghui; Pfister, Stefan M; Pajtler, Kristian W; Ellison, David W; Kool, Marcel

EPEN-05. CXorf67 EXPRESSION IS A PUTATIVE DRIVER OF PFA EPENDYMOMA

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Oxford University Press (OUP), 2018

Published in: Neuro-Oncology
Pajtler, Kristian W; Okonechnikov, Konstantin; Vouri, Mikaella; Brabetz, Sebastian; Jones, David T W; Korshunov, Andrey; Capper, David; Chavez, Lukas; Pfister, Stefan M; Kool, Marcel; Kawauchi, Daisuke

EPEN-24. YAP1 FUSION PROTEINS MEDIATE ONCOGENIC ACTIVITY IN EPENDYMOMA VIA INTERACTION WITH TEAD TRANSCRIPTION FACTORS

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Oxford University Press (OUP), 2018

Published in: Neuro-Oncology
Kawauchi, Daisuke; Clark, Jessica; Okonechnikov, Konstantin; Batora, Nadja; Vouri, Mikaella; van Rijn, Sjoerd; Gearhart, Micah; Orr, Brent; Korshunov, Andrey; Kool, Marcel; Bardwell, Vivian; Pfister, Stefan; Northcott, Paul

MBRS-07. BCOR LOSS IMPACTS SHH MEDULLOBLASTOMA FORMATION VIA TRANSCRIPTIONAL UP-REGULATION OF Igf2

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Oxford University Press (OUP), 2018

Published in: Neuro-Oncology
Tao, Ran; Murad, Najiba; Xu, Zhenhua; Zhang, Peng; Okonechnikov, Konstantin; Kool, Marcel; Rivero-Hinojosa, Samuel; Lazarski, Christopher; Zheng, Pan; Eberhart, Charles; Rood, Brian; Packer, Roger; Pei, Yanxin

PDTM-13. OVEREXPRESSION OF MYC ALONE IS SUFFICIENT TO INITIATE GROUP 3 MEDULLOBLASTOMA

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Oxford University Press (OUP), 2018

Published in: Neuro-Oncology
García-Alcalde, Fernando; Okonechnikov, Konstantin; Carbonell, José; Cruz, Luis M.; Götz, Stefan; Tarazona, Sonia; Dopazo, Joaquín; Meyer, Thomas F.; Conesa, Ana

Qualimap: evaluating next-generation sequencing alignment data

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Oxford University Press (OUP), 2012

Published in: Bioinformatics
Korshunov, Andrey; Okonechnikov, Konstantin; Schrimpf, Daniel; Tonn, Svenja; Mynarek, Martin; Koster, Jan; Sievers, Philipp; Milde, Till; Sahm, Felix; Jones, David T. W.; von Deimling, Andreas; Pfister, Stefan M.; Kool, Marcel

Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes

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Springer Science and Business Media LLC, 2023

Published in: Acta Neuropathologica
Korshunov, Andrey; Okonechnikov, Konstantin; Stichel, Damian; Schrimpf, Daniel; Delaidelli, Alberto; Tonn, Svenja; Mynarek, Martin; Sievers, Philipp; Sahm, Felix; Jones, David T. W.; von Deimling, Andreas; Pfister, Stefan M.; Kool, Marcel

Gene expression profiling of Group 3 medulloblastomas defines a clinically tractable stratification based on KIRREL2 expression

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Springer Science and Business Media LLC, 2022

Published in: Acta Neuropathologica
Morcavallo, Alaide; Barker, Karen; Kwok, Colin; Boult, Jessica K R; da Silva, Patricia Benites Goncalves; Okonechnikov, Konstantin; Zuckermann, Marc; Gorrini, Chiara; Jacques, Thomas S; Robinson, Simon P; Clifford, Steven C; Weiss, William A; Pfister, Stefan M; Kawauchi, Daisuke; Chesler, Louis

MODL-02. A novelCre-conditionalcMYC-driven MB Group 3 transgenic mouse model shows traceable leptomeningeal dissemination

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Oxford University Press (OUP), 2022

Published in: Neuro-Oncology
Delaidelli, Alberto; Dunham, Christopher; Santi, Mariarita; Negri, Gian Luca; Triscott, Joanna; Zheludkova, Olga; Golanov, Andrey; Ryzhova, Marina; Okonechnikov, Konstantin; Schrimpf, Daniel; Stichel, Damian; Ellison, David; von Deimling, Andreas; Kool, Marcel; Pfister, Stefan; Ramaswamy, Vijay; Taylor, Michael; Korshunov, Andrey; Sorensen, Poul

PATH-03. Clinically Tractable Outcome Prediction of Group 3/4 Medulloblastoma Based on TPD52 Immunohistochemistry: a Multicohort Study

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Oxford University Press (OUP), 2022

Published in: Neuro-Oncology
von Soosten, Laura; Haar, Janina; Frehtman, Veronika; Holderbach, Stefan; Belzen, Julius Upmeier zu; Jendrusch, Michael; Okonechnikov, Konstantin; Pfister, Stefan M; Grimm, Dirk; Leuchs, Barbara; Jones, David; Kutscher, Lena M; Zuckermann, Marc

THER-01. Precision brain tumor therapy by AAV-mediated oncogene editing

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Oxford University Press (OUP), 2022

Published in: Neuro-Oncology
Sarropoulos, Ioannis; Sepp, Mari; Frömel, Robert; Leiss, Kevin; Trost, Nils; Leushkin, Evgeny; Okonechnikov, Konstantin; Joshi, Piyush; Giere, Peter; Kutscher, Lena M.; Cardoso-Moreira, Margarida; Pfister, Stefan M.; Kaessmann, Henrik

Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells

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American Association for the Advancement of Science (AAAS), 2021

Published in: Science
Delaidelli, Alberto; Dunham, Christopher; Santi, Maria Rita; Negri, Gian Luca; Triscott, Joanna; Zheludkova, Olga; Golanov, Andrey; Ryzhova, Marina; Okonechnikov, Konstantin; Schrimpf, Daniel; Stichel, Damian; von Deimling, Andreas; Kool, Marcel; Pfister, Stefan; Ramaswamy, Vijay; Korshunov, Andrey; Taylor, Michael; Sorensen, Poul

EMBR-21. CLINICALLY TRACTABLE OUTCOME PREDICTION OF GROUP 3/4 MEDULLOBLASTOMA BASED ON TPD52 IMMUNOHISTOCHEMISTRY: A MULTICOHORT STUDY

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Oxford University Press (OUP), 2021

Published in: Neuro-Oncology
Korshunov, Andrey; Okonechnikov, Konstantin; Stichel, Damian; Ryzhova, Marina; Schrimpf, Daniel; Sahm, Felix; Sievers, Philipp; Absalyamova, Oksana; Zheludkova, Olga; Golanov, Andrey; Jones, David T W; Pfister, Stefan M; von Deimling, Andreas; Kool, Marcel

Integrated molecular analysis of adult sonic hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator

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Oxford University Press (OUP), 2021

Published in: Neuro-Oncology
Afanasyeva, Elena A; Gartlgruber, Moritz; Ryl, Tatsiana; Decaesteker, Bieke; Denecker, Geertrui; Mönke, Gregor; Toprak, Umut H; Florez, Andres; Torkov, Alica; Dreidax, Daniel; Herrmann, Carl; Okonechnikov, Konstantin; Ek, Sara; Sharma, Ashwini Kumar; Sagulenko, Vitaliya; Speleman, Frank; Henrich, Kai-Oliver; Westermann, Frank

Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma

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Life Science Alliance, LLC, 2021

Published in: Life Science Alliance
Morcavallo, Alaide; Barker, Karen; Adachi, Toma; Boult, Jessica K R; Kwok, Colin; da Silva, Patricia Benites Goncalves; Okonechnikov, Konstantin; Hitchen, Luke; Robinson, Simon P; Clifford, Steven C; Pfister, Stefan M; Kawauchi, Daisuke; Chesler, Louis

TMOD-03. A NOVEL MB GR3 TRANSGENIC MOUSE MODEL IS GENERATED BY MYCN AND P53 DEFECTS IN VENTRICULAR ZONE PROGENITORS

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Oxford University Press (OUP), 2021

Published in: Neuro-Oncology
Colmenero-Repiso, Ana; Gómez-Muñoz, María A.; Rodríguez-Prieto, Ismael; Amador-Álvarez, Aida; Henrich, Kai-Oliver; Pascual-Vaca, Diego; Okonechnikov, Konstantin; Rivas, Eloy; Westermann, Frank; Pardal, Ricardo; Vega, Francisco M.

Identification of VRK1 as a New Neuroblastoma Tumor Progression Marker Regulating Cell Proliferation

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MDPI AG, 2020

Published in: Cancers

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