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Beitsch, Peter; Whitworth, Pat; Hughes, Kevin; Grady, Ian; Barbosa, Karen; Patel, Rakesh; Kinney, Michael; Baron, Paul; Rosen, Barry; Compagnoni, Gia; Smith, Linda ann; Simmons, Rache; Coomer, Cynara; Holmes, Dennis; Brown, Eric; Gold, Linsey; Curcio, Lisa; Clark, Patricia; Ruiz, Tony; MacDonald, Heather; Khan, Sadia; Riley, Lee; Lyons, Sam; Yang, Shan; [...]Abstract P6-08-28: Comprehensive germline multigene panel testing changes clinical care for patients with breast cancerView onlineSchließen
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Published in: Cancer Research
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Beitsch, Peter D.; Whitworth, Pat W.; Hughes, Kevin S.; Patel, Rakesh; Baron, Paul; Rosen, Barry; Grady, Ian; Holmes, Dennis; Simmons, Rache M.; Smith, Linda Ann; Compagnoni, Gia; Coomer, Cynara L.; Brown, Eric Allen; Barbosa, Karen; Clark, Patricia; Gold, Linsey P.; Riley, Lee B.; Esplin, Edward D.; Yang, Shan; Nussbaum, Robert L.Comprehensive germline multigene panel testing changes clinical care for patients with breast cancer: Untapped clinical utility and PARP inhibitor trial eligibilityView onlineSchließen
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Published in: Journal of Clinical Oncology
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Beitsch, Peter D.; Whitworth, Pat W.; Hughes, Kevin; Patel, Rakesh; Rosen, Barry; Compagnoni, Gia; Baron, Paul; Simmons, Rache; Smith, Linda Ann; Grady, Ian; Kinney, Michael; Coomer, Cynara; Barbosa, Karen; Holmes, Dennis R.; Brown, Eric; Gold, Linsey; Clark, Patricia; Riley, Lee; Lyons, Samuel; Ruiz, Antonio; Kahn, Sadia; MacDonald, Heather; Curcio, Lisa; Hardwick, Mary Kay; [...]Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle?View onlineSchließen
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Published in: Journal of Clinical Oncology
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Coetzee, Bernard W. T.; Kremen, Claire; Cameron, Alison; Razafimpahanana, Andriamandimbisoa; Moilanen, Atte; Thomas, Chris D.; Beentje, Henk; Dransfield, John; Fisher, Brian L.; Glaw, Frank; Good, Tatjana C.; Harper, Grady J.; Hijmans, Robert J.; Lees, David C.; Louisr, Edward; Nussbaum, Ronald A.; Phillips, Steven J.; Raxworthy, Christopher J.; Schatz, George E.; Vences, Miguel; Vieites, George R.; Wright, Patricia C.; Zjhra, Michelle L.; Zjhra, L.Conservation with CaveatsView onlineSchließen
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Published in: Science
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Lowes, Michelle A.; Chamian, Francesca; Abello, Maria Veronica; Fuentes-Duculan, Judilyn; Lin, Shao-Lee; Nussbaum, Rachel; Novitskaya, Inna; Carbonaro, Henrietta; Cardinale, Irma; Kikuchi, Toyoko; Gilleaudeau, Patricia; Sullivan-Whalen, Mary; Wittkowski, Knut M.; Papp, Kim; Garovoy, Marvin; Dummer, Wolfgang; Steinman, Ralph M.; Krueger, James G.Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)View onlineSchließen
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Published in: Proceedings of the National Academy of Sciences
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Candido-dos-Reis, Francisco J.; Song, Honglin; Goode, Ellen L.; Cunningham, Julie M.; Fridley, Brooke L.; Larson, Melissa C.; Alsop, Kathryn; Dicks, Ed; Harrington, Patricia; Ramus, Susan J.; de Fazio, Anna; Mitchell, Gillian; Fereday, Sian; Bolton, Kelly L.; Gourley, Charlie; Michie, Caroline; Karlan, Beth; Lester, Jenny; Walsh, Christine; Cass, Ilana; Olsson, Håkan; Gore, Martin; Benitez, Javier J.; Garcia, Maria J.; [...]Germline Mutation in BRCA1 or BRCA2 and Ten-Year Survival for Women Diagnosed with Epithelial Ovarian CancerView onlineSchließen
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Published in: Clinical Cancer Research
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Rebbeck, Timothy R.; Friebel, Tara M.; Mitra, Nandita; Wan, Fei; Chen, Stephanie; Andrulis, Irene L.; Apostolou, Paraskevi; Arnold, Norbert; Arun, Banu K.; Barrowdale, Daniel; Benitez, Javier; Berger, Raanan; Berthet, Pascaline; Borg, Ake; Buys, Saundra S.; Caldes, Trinidad; Carter, Jonathan; Chiquette, Jocelyne; Claes, Kathleen B. M.; Couch, Fergus J.; Cybulski, Cezary; Daly, Mary B.; de la Hoya, Miguel; Diez, Orland; [...]Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 womenView onlineSchließen
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Published in: Breast Cancer Research
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Qian, Frank; Wang, Shengfeng; Mitchell, Jonathan; McGuffog, Lesley; Barrowdale, Daniel; Leslie, Goska; Oosterwijk, Jan C; Chung, Wendy K; Evans, D Gareth; Engel, Christoph; Kast, Karin; Aalfs, Cora M; Adank, Muriel A; Adlard, Julian; Agnarsson, Bjarni A; Aittomäki, Kristiina; Alducci, Elisa; Andrulis, Irene L; Arun, Banu K; Ausems, Margreet G E M; Azzollini, Jacopo; Barouk-Simonet, Emmanuelle; Barwell, Julian; Belotti, Muriel; [...]Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization StudyView onlineSchließen
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Published in: JNCI: Journal of the National Cancer Institute
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Lu, Yingchang; Beeghly-Fadiel, Alicia; Wu, Lang; Guo, Xingyi; Li, Bingshan; Schildkraut, Joellen M.; Im, Hae Kyung; Chen, Yian A.; Permuth, Jennifer B.; Reid, Brett M.; Teer, Jamie K.; Moysich, Kirsten B.; Andrulis, Irene L.; Anton-Culver, Hoda; Arun, Banu K.; Bandera, Elisa V.; Barkardottir, Rosa B.; Barnes, Daniel R.; Benitez, Javier; Bjorge, Line; Brenton, James; Butzow, Ralf; Caldes, Trinidad; Caligo, Maria A.; [...]A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer RiskView onlineSchließen
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Published in: Cancer Research
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Hamdi, Yosr; Soucy, Penny; Kuchenbaeker, Karoline B.; Pastinen, Tomi; Droit, Arnaud; Lemaçon, Audrey; Adlard, Julian; Aittomäki, Kristiina; Andrulis, Irene L.; Arason, Adalgeir; Arnold, Norbert; Arun, Banu K.; Azzollini, Jacopo; Bane, Anita; Barjhoux, Laure; Barrowdale, Daniel; Benitez, Javier; Berthet, Pascaline; Blok, Marinus J.; Bobolis, Kristie; Bonadona, Valérie; Bonanni, Bernardo; Bradbury, Angela R.; Brewer, Carole; [...]Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3View onlineSchließen
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Published in: Breast Cancer Research and Treatment
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Hoffmann, Michael; Hilton-Taylor, Craig; Angulo, Ariadne; Böhm, Monika; Brooks, Thomas M.; Butchart, Stuart H. M.; Carpenter, Kent E.; Chanson, Janice; Collen, Ben; Cox, Neil A.; Darwall, William R. T.; Dulvy, Nicholas K.; Harrison, Lucy R.; Katariya, Vineet; Pollock, Caroline M.; Quader, Suhel; Richman, Nadia I.; Rodrigues, Ana S. L.; Tognelli, Marcelo F.; Vie, Jean-Christophe; Aguiar, John M.; Allen, David J.; Allen, Gerald R.; Amori, Giovanni; [...]The Impact of Conservation on the Status of the World's VertebratesView onlineSchließen
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Published in: Science
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Hoffmann, Michael; Hilton-Taylor, Craig; Angulo, Ariadne; Böhm, Monika; Brooks, Thomas M.; Butchart, Stuart H. M.; Carpenter, Kent E.; Chanson, Janice; Collen, Ben; Cox, Neil A.; Darwall, William R. T.; Dulvy, Nicholas K.; Harrison, Lucy R.; Katariya, Vineet; Pollock, Caroline M.; Quader, Suhel; Richman, Nadia I.; Rodrigues, Ana S. L.; Tognelli, Marcelo F.; Vié, Jean-Christophe; Aguiar, John M.; Allen, David J.; Allen, Gerald R.; Amori, Giovanni; [...]The Impact of Conservation on the Status of the World’s VertebratesView onlineSchließen
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Published in: Science
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Rebbeck, Timothy R.; Friebel, Tara M.; Friedman, Eitan; Hamann, Ute; Huo, Dezheng; Kwong, Ava; Olah, Edith; Olopade, Olufunmilayo I.; Solano, Angela R.; Teo, Soo-Hwang; Thomassen, Mads; Weitzel, Jeffrey N.; Chan, TL; Couch, Fergus J.; Goldgar, David E.; Kruse, Torben A.; Palmero, Edenir Inêz; Park, Sue Kyung; Torres, Diana; van Rensburg, Elizabeth J.; McGuffog, Lesley; Parsons, Michael T.; Leslie, Goska; Aalfs, Cora M.; [...]Mutational spectrum in a worldwide study of 29,700 families withBRCA1orBRCA2mutationsView onlineSchließen
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Published in: Human Mutation
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Meeks, Huong D.; Song, Honglin; Michailidou, Kyriaki; Bolla, Manjeet K.; Dennis, Joe; Wang, Qin; Barrowdale, Daniel; Frost, Debra; McGuffog, Lesley; Ellis, Steve; Feng, Bingjian; Buys, Saundra S.; Hopper, John L.; Southey, Melissa C.; Tesoriero, Andrea; James, Paul A.; Bruinsma, Fiona; Campbell, Ian G.; Broeks, Annegien; Schmidt, Marjanka K.; Hogervorst, Frans B. L.; Beckman, Matthias W.; Fasching, Peter A.; Fletcher, Olivia; [...]BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian CancersView onlineSchließen
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Published in: Journal of the National Cancer Institute
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Dunning, Alison M; Michailidou, Kyriaki; Kuchenbaecker, Karoline B; Thompson, Deborah; French, Juliet D; Beesley, Jonathan; Healey, Catherine S; Kar, Siddhartha; Pooley, Karen A; Lopez-Knowles, Elena; Dicks, Ed; Barrowdale, Daniel; Sinnott-Armstrong, Nicholas A; Sallari, Richard C; Hillman, Kristine M; Kaufmann, Susanne; Sivakumaran, Haran; Marjaneh, Mahdi Moradi; Lee, Jason S; Hills, Margaret; Jarosz, Monika; Drury, Suzie; Canisius, Sander; Bolla, Manjeet K; [...]Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170View onlineSchließen
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Published in: Nature Genetics
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Couch, Fergus J.; Kuchenbaecker, Karoline B.; Michailidou, Kyriaki; Mendoza-Fandino, Gustavo A.; Nord, Silje; Lilyquist, Janna; Olswold, Curtis; Hallberg, Emily; Agata, Simona; Ahsan, Habibul; Aittomäki, Kristiina; Ambrosone, Christine; Andrulis, Irene L.; Anton-Culver, Hoda; Arndt, Volker; Arun, Banu K.; Arver, Brita; Barile, Monica; Barkardottir, Rosa B.; Barrowdale, Daniel; Beckmann, Lars; Beckmann, Matthias W.; Benitez, Javier; Blank, Stephanie V.; [...]Identification of four novel susceptibility loci for oestrogen receptor negative breast cancerView onlineSchließen
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Published in: Nature Communications
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Rebbeck, Timothy R.; Mitra, Nandita; Wan, Fei; Sinilnikova, Olga M.; Healey, Sue; McGuffog, Lesley; Mazoyer, Sylvie; Chenevix-Trench, Georgia; Easton, Douglas F.; Antoniou, Antonis C.; Nathanson, Katherine L.; Laitman, Yael; Kushnir, Anya; Paluch-Shimon, Shani; Berger, Raanan; Zidan, Jamal; Friedman, Eitan; Ehrencrona, Hans; Stenmark-Askmalm, Marie; Einbeigi, Zakaria; Loman, Niklas; Harbst, Katja; Rantala, Johanna; Melin, Beatrice; [...]Association of Type and Location ofBRCA1andBRCA2Mutations With Risk of Breast and Ovarian CancerView onlineSchließen
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Published in: JAMA
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Ferreira, Manuel A.; Gamazon, Eric R.; Al-Ejeh, Fares; Aittomäki, Kristiina; Andrulis, Irene L.; Anton-Culver, Hoda; Arason, Adalgeir; Arndt, Volker; Aronson, Kristan J.; Arun, Banu K.; Asseryanis, Ella; Azzollini, Jacopo; Balmaña, Judith; Barnes, Daniel R.; Barrowdale, Daniel; Beckmann, Matthias W.; Behrens, Sabine; Benitez, Javier; Bermisheva, Marina; Białkowska, Katarzyna; Blomqvist, Carl; Bogdanova, Natalia V.; Bojesen, Stig E.; Bolla, Manjeet K.; [...]Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancerView onlineSchließen
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Published in: Nature Communications
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Phelan, Catherine M; Kuchenbaecker, Karoline B; Tyrer, Jonathan P; Kar, Siddhartha P; Lawrenson, Kate; Winham, Stacey J; Dennis, Joe; Pirie, Ailith; Riggan, Marjorie J; Chornokur, Ganna; Earp, Madalene A; Lyra, Paulo C; Lee, Janet M; Coetzee, Simon; Beesley, Jonathan; McGuffog, Lesley; Soucy, Penny; Dicks, Ed; Lee, Andrew; Barrowdale, Daniel; Lecarpentier, Julie; Leslie, Goska; Aalfs, Cora M; Aben, Katja K H; [...]Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancerView onlineSchließen
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Published in: Nature Genetics
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Jiang, Xia; Finucane, Hilary K.; Schumacher, Fredrick R.; Schmit, Stephanie L.; Tyrer, Jonathan P.; Han, Younghun; Michailidou, Kyriaki; Lesseur, Corina; Kuchenbaecker, Karoline B.; Dennis, Joe; Conti, David V.; Casey, Graham; Gaudet, Mia M.; Huyghe, Jeroen R.; Albanes, Demetrius; Aldrich, Melinda C.; Andrew, Angeline S.; Andrulis, Irene L.; Anton-Culver, Hoda; Antoniou, Antonis C.; Antonenkova, Natalia N.; Arnold, Susanne M.; Aronson, Kristan J.; Arun, Banu K.; [...]Publisher Correction: Shared heritability and functional enrichment across six solid cancersView onlineSchließen
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Published in: Nature Communications