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Lenz, Max; Salzmann, Manuel; Ciotu, Cosmin I.; Kaun, Christoph; Krychtiuk, Konstantin A.; Rehberger Likozar, Andreja; Sebestjen, Miran; Goederle, Laura; Rauscher, Sabine; Krivaja, Zoriza; Binder, Christoph J.; Huber, Kurt; Hengstenberg, Christian; Podesser, Bruno K.; Fischer, Michael J. M.; Wojta, Johann; Hohensinner, Philipp J.; Speidl, Walter S.Pharmacologic modulation of intracellular Na+concentration with ranolazine impacts inflammatory response in humans and miceView onlineSchließen
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Published in: Proceedings of the National Academy of Sciences
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Wu, Yi-Long; John, Thomas; Grohe, Christian; Majem, Margarita; Goldman, Jonathan W.; Kim, Sang-We; Kato, Terufumi; Laktionov, Konstantin; Vu, Huu Vinh; Wang, Zhijie; Lu, Shun; Lee, Kye Young; Akewanlop, Charuwan; Yu, Chong-Jen; de Marinis, Filippo; Bonanno, Laura; Domine, Manuel; Shepherd, Frances A.; Zeng, Lingmin; Atasoy, Ajlan; Herbst, Roy S.; Tsuboi, MasahiroPostoperative Chemotherapy Use and Outcomes From ADAURA: Osimertinib as Adjuvant Therapy for Resected EGFR-Mutated NSCLCView onlineSchließen
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Published in: Journal of Thoracic Oncology
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Wu, Yi-Long; Tsuboi, Masahiro; He, Jie; John, Thomas; Grohe, Christian; Majem, Margarita; Goldman, Jonathan W.; Laktionov, Konstantin; Kim, Sang-We; Kato, Terufumi; Vu, Huu-Vinh; Lu, Shun; Lee, Kye-Young; Akewanlop, Charuwan; Yu, Chong-Jen; de Marinis, Filippo; Bonanno, Laura; Domine, Manuel; Shepherd, Frances A.; Zeng, Lingmin; Hodge, Rachel; Atasoy, Ajlan; Rukazenkov, Yuri; Herbst, Roy S.Osimertinib in ResectedEGFR-Mutated Non–Small-Cell Lung CancerView onlineSchließen
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Published in: New England Journal of Medicine
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Brendlin, Andreas Stefan; Molwitz, Isabel; Oechtering, Thekla Helene; Barkhausen, Jörg; Frydrychowicz, Alex; Sulkowski, Tanja; Balks, Maren Friederike; Buchholz, Michael; Lohwasser, Stefan; Völker, Martin; Goldschmidt, Olaf; Johenning, Anja; Schlender, Sabine; Paulus, Christian; Antoch, Gerald; Dettmer, Sabine; Baeßler, Bettina; Maintz, David; Pinto dos Santos, Daniel; Vogl, Thomas J.; Hattingen, Elke; Stoevesandt, Dietrich; Reinartz, Sebastian; Storz, Corinna; [...]CoRad-19 – Modular Digital Teaching during the SARS-CoV-2 PandemicView onlineSchließen
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Published in: RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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Uderhardt, Stefan; Ackermann, Jochen A.; Fillep, Tobias; Hammond, Victoria J.; Willeit, Johann; Santer, Peter; Mayr, Manuel; Biburger, Markus; Miller, Meike; Zellner, Katie R.; Stark, Konstantin; Zarbock, Alexander; Rossaint, Jan; Schubert, Irene; Mielenz, Dirk; Dietel, Barbara; Raaz-Schrauder, Dorette; Ay, Cihan; Gremmel, Thomas; Thaler, Johannes; Heim, Christian; Herrmann, Martin; Collins, Peter W.; Schabbauer, Gernot; [...]Correction: Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic diseaseView onlineSchließen
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Published in: Journal of Experimental Medicine
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Uderhardt, Stefan; Ackermann, Jochen A.; Fillep, Tobias; Hammond, Victoria J.; Willeit, Johann; Santer, Peter; Mayr, Manuel; Biburger, Markus; Miller, Meike; Zellner, Katie R.; Stark, Konstantin; Zarbock, Alexander; Rossaint, Jan; Schubert, Irene; Mielenz, Dirk; Dietel, Barbara; Raaz-Schrauder, Dorette; Ay, Cihan; Gremmel, Thomas; Thaler, Johannes; Heim, Christian; Herrmann, Martin; Collins, Peter W.; Schabbauer, Gernot; [...]Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic diseaseView onlineSchließen
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Published in: Journal of Experimental Medicine
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Grosche, Sarah; Marenholz, Ingo; Esparza-Gordillo, Jorge; Arnau-Soler, Aleix; Pairo-Castineira, Erola; Rüschendorf, Franz; Ahluwalia, Tarunveer S.; Almqvist, Catarina; Arnold, Andreas; Baurecht, Hansjörg; Bisgaard, Hans; Bønnelykke, Klaus; Brown, Sara J.; Bustamante, Mariona; Curtin, John A.; Custovic, Adnan; Dharmage, Shyamali C.; Esplugues, Ana; Falchi, Mario; Fernandez-Orth, Dietmar; Ferreira, Manuel A. R.; Franke, Andre; Gerdes, Sascha; Gieger, Christian; [...]Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4View onlineSchließen
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Published in: Nature Communications
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Ferreira, Manuel A; Vonk, Judith M; Baurecht, Hansjörg; Marenholz, Ingo; Tian, Chao; Hoffman, Joshua D; Helmer, Quinta; Tillander, Annika; Ullemar, Vilhelmina; van Dongen, Jenny; Lu, Yi; Rüschendorf, Franz; Esparza-Gordillo, Jorge; Medway, Chris W; Mountjoy, Edward; Burrows, Kimberley; Hummel, Oliver; Grosche, Sarah; Brumpton, Ben M; Witte, John S; Hottenga, Jouke-Jan; Willemsen, Gonneke; Zheng, Jie; Rodríguez, Elke; [...]Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biologyView onlineSchließen
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Published in: Nature Genetics
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Garnier, Sophie; Harakalova, Magdalena; Weiss, Stefan; Mokry, Michal; Regitz-Zagrosek, Vera; Hengstenberg, Christian; Cappola, Thomas P; Isnard, Richard; Arbustini, Eloisa; Cook, Stuart A; van Setten, Jessica; Calis, Jorg J A; Hakonarson, Hakon; Morley, Michael P; Stark, Klaus; Prasad, Sanjay K; Li, Jin; O'Regan, Declan P; Grasso, Maurizia; Müller-Nurasyid, Martina; Meitinger, Thomas; Empana, Jean-Philippe; Strauch, Konstantin; Waldenberger, Melanie; [...]Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23View onlineSchließen
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Published in: European Heart Journal
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Low, Donald E.; File, Thomas M.; Eckburg, Paul B.; Talbot, George H.; David Friedland, H.; Lee, Jon; Llorens, Lily; Critchley, Ian A.; Thye, Dirk A.; Corral, Jorge; Giugno, Eduardo; Gonzalez Arzac, Maria del Rosario; Maurizi, Diego; Altclas, Javier; Ambasch, Germán; Jasovich, Abel; Minguez, Angel Ramon; Oliva, Maria Eugenia; Teglia, Osvaldo; Bergallo, Carlos; Mastruzzo, Maria Antonia; Isabel Morera, Graciana; Scapellato, Pabio Gustavo; Lamberghini, Ricardo; [...]FOCUS 2: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumoniaView onlineSchließen
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Published in: Journal of Antimicrobial Chemotherapy
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Byrne, Robert A; Rossello, Xavier; Coughlan, J J; Barbato, Emanuele; Berry, Colin; Chieffo, Alaide; Claeys, Marc J; Dan, Gheorghe-Andrei; Dweck, Marc R; Galbraith, Mary; Gilard, Martine; Hinterbuchner, Lynne; Jankowska, Ewa A; Jüni, Peter; Kimura, Takeshi; Kunadian, Vijay; Leosdottir, Margret; Lorusso, Roberto; Pedretti, Roberto F E; Rigopoulos, Angelos G; Rubini Gimenez, Maria; Thiele, Holger; Vranckx, Pascal; Wassmann, Sven; [...]2023 ESC Guidelines for the management of acute coronary syndromesView onlineSchließen
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Published in: European Heart Journal: Acute Cardiovascular Care
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Breznau, Nate; Rinke, Eike Mark; Wuttke, Alexander; Nguyen, Hung H. V.; Adem, Muna; Adriaans, Jule; Alvarez-Benjumea, Amalia; Andersen, Henrik K.; Auer, Daniel; Azevedo, Flavio; Bahnsen, Oke; Balzer, Dave; Bauer, Gerrit; Bauer, Paul C.; Baumann, Markus; Baute, Sharon; Benoit, Verena; Bernauer, Julian; Berning, Carl; Berthold, Anna; Bethke, Felix S.; Biegert, Thomas; Blinzler, Katharina; Blumenberg, Johannes N.; [...]Observing many researchers using the same data and hypothesis reveals a hidden universe of uncertaintyView onlineSchließen
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Published in: Proceedings of the National Academy of Sciences
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Flannick, Jason; Mercader, Josep M.; Fuchsberger, Christian; Udler, Miriam S.; Mahajan, Anubha; Wessel, Jennifer; Teslovich, Tanya M.; Caulkins, Lizz; Koesterer, Ryan; Barajas-Olmos, Francisco; Blackwell, Thomas W.; Boerwinkle, Eric; Brody, Jennifer A.; Centeno-Cruz, Federico; Chen, Ling; Chen, Siying; Contreras-Cubas, Cecilia; Córdova, Emilio; Correa, Adolfo; Cortes, Maria; DeFronzo, Ralph A.; Dolan, Lawrence; Drews, Kimberly L.; Elliott, Amanda; [...]Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controlsView onlineSchließen
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Published in: Nature
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Goodrich, Julia K.; Singer-Berk, Moriel; Son, Rachel; Sveden, Abigail; Wood, Jordan; England, Eleina; Cole, Joanne B.; Weisburd, Ben; Watts, Nick; Caulkins, Lizz; Dornbos, Peter; Koesterer, Ryan; Zappala, Zachary; Zhang, Haichen; Maloney, Kristin A.; Dahl, Andy; Aguilar-Salinas, Carlos A.; Atzmon, Gil; Barajas-Olmos, Francisco; Barzilai, Nir; Blangero, John; Boerwinkle, Eric; Bonnycastle, Lori L.; Bottinger, Erwin; [...]Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomesView onlineSchließen
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Published in: Nature Communications
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Campos, Niklas S.; Bluth, Thomas; Hemmes, Sabrine N.T.; Librero, Julian; Pozo, Natividad; Ferrando, Carlos; Ball, Lorenzo; Mazzinari, Guido; Pelosi, Paolo; Gama de Abreu, Marcelo; Schultz, Marcus J.; Serpa Neto, A.; Hemmes, Sabrine NT.; Gama de Abreu, Marcelo; Severgnini, Paolo; Hollmann, Markus W.; Binnekade, Jan M.; Wrigge, Hermann; Canet, Jaume; Hiesmayr, Michael; Schmid, Werner; Tschernko, Edda; Jaber, Samir; Hedenstierna, Göran; [...]Intraoperative positive end-expiratory pressure and postoperative pulmonary complications: a patient-level meta-analysis of three randomised clinical trialsView onlineSchließen
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Published in: British Journal of Anaesthesia
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Prandoni, Paolo; Haas, Sylvia; Fluharty, Meg E.; Schellong, Sebastian; Gibbs, Harry; Tse, Eric; Carrier, Marc; Jacobson, Barry; ten Cate, Hugo; Panchenko, Elizaveta; Verhamme, Peter; Pieper, Karen; Kayani, Gloria; Kakkar, Lord A.; Abdullah, Nik; Abiko, Akihiko; Abril, Juan; Acevedo, David; Adademir, Taylan; Adler, David; Ageno, Walter; Agnelli, Giancarlo; Ahmed, Mostafa; Aksoy, Ahmet; [...]Incidence and predictors of post-thrombotic syndrome in patients with proximal DVT in a real-world setting: findings from the GARFIELD-VTE registryView onlineSchließen
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Published in: Journal of Thrombosis and Thrombolysis
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Wheeler, Eleanor; Leong, Aaron; Liu, Ching-Ti; Hivert, Marie-France; Strawbridge, Rona J.; Podmore, Clara; Li, Man; Yao, Jie; Sim, Xueling; Hong, Jaeyoung; Chu, Audrey Y.; Zhang, Weihua; Wang, Xu; Chen, Peng; Maruthur, Nisa M.; Porneala, Bianca C.; Sharp, Stephen J.; Jia, Yucheng; Kabagambe, Edmond K.; Chang, Li-Ching; Chen, Wei-Min; Elks, Cathy E.; Evans, Daniel S.; Fan, Qiao; [...]Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysisView onlineSchließen
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Published in: PLOS Medicine
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Manning, Alisa; Highland, Heather M.; Gasser, Jessica; Sim, Xueling; Tukiainen, Taru; Fontanillas, Pierre; Grarup, Niels; Rivas, Manuel A.; Mahajan, Anubha; Locke, Adam E.; Cingolani, Pablo; Pers, Tune H.; Viñuela, Ana; Brown, Andrew A.; Wu, Ying; Flannick, Jason; Fuchsberger, Christian; Gamazon, Eric R.; Gaulton, Kyle J.; Im, Hae Kyung; Teslovich, Tanya M.; Blackwell, Thomas W.; Bork-Jensen, Jette; Burtt, Noël P.; [...]A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes RiskView onlineSchließen
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Published in: Diabetes
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Weitz, Jeffrey I.; Haas, Sylvia; Ageno, Walter; Goldhaber, Samuel Z.; Turpie, Alexander G. G.; Goto, Shinya; Angchaisuksiri, Pantep; Nielsen, Jørn Dalsgaard; Kayani, Gloria; Farjat, Alfredo E.; Schellong, Sebastian; Bounameaux, Henri; Mantovani, Lorenzo G.; Prandoni, Paolo; Kakkar, Ajay K.; Loualidi, Ab; Colak, Abdurrahim; Bezuidenhout, Abraham; Abdool-Carrim, Abu; Azeddine, Addala; Beyers, Adriaan; Dees, Adriaan; Mohamed, Ahmed; Aksoy, Ahmet; [...]Cancer associated thrombosis in everyday practice: perspectives from GARFIELD-VTEView onlineSchließen
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Published in: Journal of Thrombosis and Thrombolysis
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Haas, Sylvia; Ageno, Walter; Weitz, Jeffrey I.; Goldhaber, Samuel Z.; Turpie, Alexander G.G.; Goto, Shinya; Angchaisuksiri, Pantep; Dalsgaard Nielsen, Joern; Kayani, Gloria; Zaghdoun, Audrey; Farjat, Alfredo E.; Schellong, Sebastian; Bounameaux, Henri; Mantovani, Lorenzo G.; Prandoni, Paolo; Kakkar, Ajay K.; Loualidi, Ab; Colak, Abdurrahim; Bezuidenhout, Abraham; Abdool‐Carrim, Abu; Azeddine, Addala; Beyers, Adriaan; Dees, Adriaan; Mohamed, Ahmed; [...]Anticoagulation therapy patterns for acute treatment of venous thromboembolism in GARFIELD‐VTE patientsView onlineSchließen
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Published in: Journal of Thrombosis and Haemostasis