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Wolf, Annika; Keil, Rene; Götzl, Oliver; Mun, Andrej; Schwarze, Katrin; Lederer, Marcell; Hüttelmaier, Stefan; Hatzfeld, Mechthild

The armadillo protein p0071 regulates Rho signalling during cytokinesis

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Springer Science and Business Media LLC, 2006

Published in: Nature Cell Biology, 8 (2006) 12, Seite 1432-1440
Stöhr, Nadine; Lederer, Marcell; Reinke, Claudia; Meyer, Sylke; Hatzfeld, Mechthild; Singer, Robert H.; Hüttelmaier, Stefan

ZBP1 regulates mRNA stability during cellular stress

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Rockefeller University Press, 2006

Published in: The Journal of Cell Biology, 175 (2006) 4, Seite 527-534
Tänzler, Dirk; Kipping, Marc; Lederer, Marcell; Günther, Wiebke F.; Arlt, Christian; Hüttelmaier, Stefan; Merkenschlager, Andreas; Sinz, Andrea

Effects of theophylline on ADCY5 activation—From cellular studies to improved therapeutic options for ADCY5-related dyskinesia patients

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Public Library of Science (PLoS), 2023

Published in: PLOS ONE, 18 (2023) 3, Seite e0282593
Misiak, Danny; Hagemann, Sven; Bell, Jessica L.; Busch, Bianca; Lederer, Marcell; Bley, Nadine; Schulte, Johannes H.; Hüttelmaier, Stefan

The MicroRNA Landscape of MYCN-Amplified Neuroblastoma

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Frontiers Media SA, 2021

Published in: Frontiers in Oncology, 11 (2021)
Müller, Simon; Bley, Nadine; Glaß, Markus; Busch, Bianca; Rousseau, Vanessa; Misiak, Danny; Fuchs, Tommy; Lederer, Marcell; Hüttelmaier, Stefan

IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors

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Oxford University Press (OUP), 2018

Published in: Nucleic Acids Research, 46 (2018) 12, Seite 6285-6303
Nolze, Alexander; Schneider, Jacqueline; Keil, René; Lederer, Marcell; Hüttelmaier, Stefan; Kessels, Michael M.; Qualmann, Britta; Hatzfeld, Mechthild

FMRP regulates actin filament organization via the armadillo protein p0071

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Cold Spring Harbor Laboratory, 2013

Published in: RNA, 19 (2013) 11, Seite 1483-1496
Weidensdorfer, Doreen; Stöhr, Nadine; Baude, Anne; Lederer, Marcell; Köhn, Marcel; Schierhorn, Angelika; Buchmeier, Sabine; Wahle, Elmar; Hüttelmaier, Stefan

Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs

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Cold Spring Harbor Laboratory, 2009

Published in: RNA, 15 (2009) 1, Seite 104-115
Hagemann, Sven; Misiak, Danny; Bell, Jessica L.; Fuchs, Tommy; Lederer, Marcell I.; Bley, Nadine; Hämmerle, Monika; Ghazy, Ehab; Sippl, Wolfgang; Schulte, Johannes H.; Hüttelmaier, Stefan

IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression

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Springer Science and Business Media LLC, 2023

Published in: Molecular Cancer, 22 (2023) 1
Müller, Simon; Bley, Nadine; Busch, Bianca; Glaß, Markus; Lederer, Marcell; Misiak, Claudia; Fuchs, Tommy; Wedler, Alice; Haase, Jacob; Bertoldo, Jean Borges; Michl, Patrick; Hüttelmaier, Stefan

The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer

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Oxford University Press (OUP), 2020

Published in: Nucleic Acids Research, 48 (2020) 15, Seite 8576-8590
Müller, Simon; Glaß, Markus; Singh, Anurag K; Haase, Jacob; Bley, Nadine; Fuchs, Tommy; Lederer, Marcell; Dahl, Andreas; Huang, Huilin; Chen, Jianjun; Posern, Guido; Hüttelmaier, Stefan

IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner

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Oxford University Press (OUP), 2019

Published in: Nucleic Acids Research, 47 (2019) 1, Seite 375-390
Busch, Bianca; Bley, Nadine; Müller, Simon; Glaß, Markus; Misiak, Danny; Lederer, Marcell; Vetter, Martina; Strauß, Hans-Georg; Thomssen, Christoph; Hüttelmaier, Stefan

The oncogenic triangle of HMGA2, LIN28B and IGF2BP1 antagonizes tumor-suppressive actions of the let-7 family

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Oxford University Press (OUP), 2016

Published in: Nucleic Acids Research, 44 (2016) 8, Seite 3845-3864
Hüttelmaier, Stefan; Zenklusen, Daniel; Lederer, Marcell; Dictenberg, Jason; Lorenz, Mike; Meng, XiuHua; Bassell, Gary J.; Condeelis, John; Singer, Robert H.

Spatial regulation of β-actin translation by Src-dependent phosphorylation of ZBP1

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Springer Science and Business Media LLC, 2005

Published in: Nature, 438 (2005) 7067, Seite 512-515
Wedler, Alice; Bley, Nadine; Glaß, Markus; Müller, Simon; Rausch, Alexander; Lederer, Marcell; Urbainski, Julia; Schian, Laura; Obika, Kingsley-Benjamin; Simon, Theresa; Peters, Lara Meret; Misiak, Claudia; Fuchs, Tommy; Köhn, Marcel; Jacob, Roland; Gutschner, Tony; Ihling, Christian; Sinz, Andrea; Hüttelmaier, Stefan

RAVER1 hinders lethal EMT and modulates miR/RISC activity by the control of alternative splicing

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Oxford University Press (OUP), 2024

Published in: Nucleic Acids Research, 52 (2024) 7, Seite 3971-3988
Bley, Nadine; Schott, Annekatrin; Müller, Simon; Misiak, Danny; Lederer, Marcell; Fuchs, Tommy; Aßmann, Chris; Glaß, Markus; Ihling, Christian; Sinz, Andrea; Pazaitis, Nikolaos; Wickenhauser, Claudia; Vetter, Martina; Ungurs, Olga; Strauss, Hans-Georg; Thomssen, Christoph; Hüttelmaier, Stefan

IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer

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Informa UK Limited, 2021

Published in: RNA Biology, 18 (2021) 3, Seite 391-403
Müller, Simon; Wedler, Alice; Breuer, Janina; Glaß, Markus; Bley, Nadine; Lederer, Marcell; Haase, Jacob; Misiak, Claudia; Fuchs, Tommy; Ottmann, Alina; Schmachtel, Tessa; Shalamova, Lyudmila; Ewe, Alexander; Aigner, Achim; Rossbach, Oliver; Hüttelmaier, Stefan

Synthetic circular miR-21 RNA decoys enhance tumor suppressor expression and impair tumor growth in mice

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Oxford University Press (OUP), 2020

Published in: NAR Cancer, 2 (2020) 3

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