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Rudan Njavro, Jasenka [Author]; Klotz, Jakob [Author]; Dislich, Bastian [Author]; Wanngren, Johanna [Author]; Shmueli, Merav D. [Author]; Herber, Julia [Author]; Kuhn, Peer-Hendrik [Author]; Kumar, Rohit [Author]; Köglsperger, Thomas [Author]; Conrad, Marcus [Author]; Wurst, Wolfgang [Author]; Feederle, Regina [Author]; Vlachos, Andreas [Author]; Michalakis, Stylianos [Author]; Jedlička, Peter [Author]; Müller, Stephan Andreas [Author]; Lichtenthaler, Stefan [Author]

Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1

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Hoboken, NJ: Wiley, 2020

Published in: The FASEB Journal ; 34, 2 (2020), 2465-2482
Shmueli, Merav D.; Sheban, Daoud; Eisenberg‐Lerner, Avital; Merbl, Yifat

Histone degradation by the proteasome regulates chromatin and cellular plasticity

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Wiley, 2022

Published in: The FEBS Journal, 289 (2022) 12, Seite 3304-3316
Shmueli, Merav D.; Levy-Kanfo, Limor; Haj, Esraa; Schoenfeld, Alan R.; Gazit, Ehud; Segal, Daniel

Arginine refolds, stabilizes, and restores function of mutant pVHL proteins in animal model of the VHL cancer syndrome

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Springer Science and Business Media LLC, 2019

Published in: Oncogene, 38 (2019) 7, Seite 1038-1049
Shmueli, Merav D.; Hizkiahou, Noa; Peled, Sivan; Gazit, Ehud; Segal, Daniel

Total proteome turbidity assay for tracking global protein aggregation in the natural cellular environment

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Journal of Biological Methods, 2017

Published in: Journal of Biological Methods, 4 (2017) 2, Seite e69
Shmueli, Merav D.; Schnaider, Lee; Herzog, Gal; Gazit, Ehud; Segal, Daniel

Computational and Experimental Characterization of dVHL Establish a Drosophila Model of VHL Syndrome

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Public Library of Science (PLoS), 2014

Published in: PLoS ONE, 9 (2014) 10, Seite e109864
Shmueli, Merav D.; Schnaider, Lee; Rosenblum, Daniel; Herzog, Gal; Gazit, Ehud; Segal, Daniel

Structural Insights into the Folding Defects of Oncogenic pVHL Lead to Correction of Its Function In Vitro

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Public Library of Science (PLoS), 2013

Published in: PLoS ONE, 8 (2013) 6, Seite e66333
Herzog, Gal; Joerger, Andreas C.; Shmueli, Merav D.; Fersht, Alan R.; Gazit, Ehud; Segal, Daniel

Evaluating Drosophila p53 as a Model System for Studying Cancer Mutations

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Elsevier BV, 2012

Published in: Journal of Biological Chemistry, 287 (2012) 53, Seite 44330-44337
Herzog, Gal; Shmueli, Merav D.; Levy, Limor; Engel, Liat; Gazit, Ehud; Klärner, Frank-Gerrit; Schrader, Thomas; Bitan, Gal; Segal, Daniel

The Lys-Specific Molecular Tweezer, CLR01, Modulates Aggregation of the Mutant p53 DNA Binding Domain and Inhibits Its Toxicity

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American Chemical Society (ACS), 2015

Published in: Biochemistry, 54 (2015) 24, Seite 3729-3738
Müller, Stephan A.; Shmueli, Merav D.; Feng, Xiao; Tüshaus, Johanna; Schumacher, Neele; Clark, Ryan; Smith, Brad E.; Chi, An; Rose-John, Stefan; Kennedy, Matthew E.; Lichtenthaler, Stefan F.

The Alzheimer’s disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130

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Springer Science and Business Media LLC, 2023

Published in: Molecular Neurodegeneration, 18 (2023) 1
Levy, Ronen; Alter Regev, Tal; Paes, Wayne; Gumpert, Nofar; Cohen Shvefel, Sapir; Bartok, Osnat; Dayan-Rubinov, Maria; Alon, Michal; Shmueli, Merav D.; Levin, Yishai; Merbl, Yifat; Ternette, Nicola; Samuels, Yardena

Large-Scale Immunopeptidome Analysis Reveals Recurrent Posttranslational Splicing of Cancer- and Immune-Associated Genes

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Elsevier BV, 2023

Published in: Molecular & Cellular Proteomics, 22 (2023) 4, Seite 100519
Rudan Njavro, Jasenka; Klotz, Jakob; Dislich, Bastian; Wanngren, Johanna; Shmueli, Merav D.; Herber, Julia; Kuhn, Peer‐Hendrik; Kumar, Rohit; Koeglsperger, Thomas; Conrad, Marcus; Wurst, Wolfgang; Feederle, Regina; Vlachos, Andreas; Michalakis, Stylianos; Jedlicka, Peter; Müller, Stephan A.; Lichtenthaler, Stefan F.

Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1

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Wiley, 2020

Published in: The FASEB Journal, 34 (2020) 2, Seite 2465-2482
Papadopoulou, Alkmini A; Müller, Stephan A; Mentrup, Torben; Shmueli, Merav D; Niemeyer, Johannes; Haug‐Kröper, Martina; von Blume, Julia; Mayerhofer, Artur; Feederle, Regina; Schröder, Bernd; Lichtenthaler, Stefan F; Fluhrer, Regina

Signal peptide peptidase‐like 2c impairs vesicular transport and cleaves SNARE proteins

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Springer Science and Business Media LLC, 2019

Published in: EMBO reports, 20 (2019) 3
Papadopoulou, Alkmini A; Müller, Stephan A; Mentrup, Torben; Shmueli, Merav D; Niemeyer, Johannes; Haug‐Kröper, Martina; von Blume, Julia; Mayerhofer, Artur; Feederle, Regina; Schröder, Bernd; Lichtenthaler, Stefan F; Fluhrer, Regina

Signal peptide peptidase‐like 2c impairs vesicular transport and cleaves SNARE proteins

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Springer Science and Business Media LLC, 2019

Published in: EMBO reports, 20 (2019) 5
Kacen, Assaf; Javitt, Aaron; Kramer, Matthias P.; Morgenstern, David; Tsaban, Tomer; Shmueli, Merav D.; Teo, Guo Ci; da Veiga Leprevost, Felipe; Barnea, Eilon; Yu, Fengchao; Admon, Arie; Eisenbach, Lea; Samuels, Yardena; Schueler-Furman, Ora; Levin, Yishai; Nesvizhskii, Alexey I.; Merbl, Yifat

Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors

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Springer Science and Business Media LLC, 2023

Published in: Nature Biotechnology, 41 (2023) 2, Seite 239-251
Benyair, Ron; Panapakkam Giridharan, Sai Srinivas; Rivero-Ríos, Pilar; Hasegawa, Junya; Bristow, Emily; Eskelinen, Eeva-Liisa; Shmueli, Merav D; Fishbain-Yoskovitz, Vered; Merbl, Yifat; Sharkey, Lisa M; Paulson, Henry L.; Hanson, Phyllis I; Patnaik, Samarjit; Al-Ramahi, Ismael; Botas, Juan; Marugan, Juan; Weisman, Lois S.

Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration

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Informa UK Limited, 2023

Published in: Autophagy Reports, 2 (2023) 1
Sheban, Daoud; Shani, Tom; Maor, Roey; Aguilera-Castrejon, Alejandro; Mor, Nofar; Oldak, Bernardo; Shmueli, Merav D.; Eisenberg-Lerner, Avital; Bayerl, Jonathan; Hebert, Jakob; Viukov, Sergey; Chen, Guoyun; Kacen, Assaf; Krupalnik, Vladislav; Chugaeva, Valeriya; Tarazi, Shadi; Rodríguez-delaRosa, Alejandra; Zerbib, Mirie; Ulman, Adi; Masarwi, Solaiman; Kupervaser, Meital; Levin, Yishai; Shema, Efrat; David, Yael; [...]

SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity

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Elsevier BV, 2022

Published in: Molecular Cell, 82 (2022) 1, Seite 106-122.e9
Eisenberg-Lerner, Avital; Benyair, Ron; Hizkiahou, Noa; Nudel, Neta; Maor, Roey; Kramer, Matthias P.; Shmueli, Merav D.; Zigdon, Inbal; Cherniavsky Lev, Marina; Ulman, Adi; Sagiv, Jitka Yehudith; Dayan, Molly; Dassa, Bareket; Rosenwald, Mercedes; Shachar, Idit; Li, Jie; Wang, Yanzhuang; Dezorella, Nili; Khan, Suman; Porat, Ziv; Shimoni, Eyal; Avinoam, Ori; Merbl, Yifat

Golgi organization is regulated by proteasomal degradation

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Springer Science and Business Media LLC, 2020

Published in: Nature Communications, 11 (2020) 1
Pigoni, Martina; Hsia, Hung‐En; Hartmann, Jana; Rudan Njavro, Jasenka; Shmueli, Merav D; Müller, Stephan A; Güner, Gökhan; Tüshaus, Johanna; Kuhn, Peer‐Hendrik; Kumar, Rohit; Gao, Pan; Tran, Mai Ly; Ramazanov, Bulat; Blank, Birgit; Hipgrave Ederveen, Agnes L; Von Blume, Julia; Mulle, Christophe; Gunnersen, Jenny M; Wuhrer, Manfred; Rammes, Gerhard; Busche, Marc Aurel; Koeglsperger, Thomas; Lichtenthaler, Stefan F

Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3

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Springer Science and Business Media LLC, 2020

Published in: The EMBO Journal, 39 (2020) 15
Mazor, Roei D.; Nathan, Nachum; Gilboa, Amit; Stoler-Barak, Liat; Moss, Lihee; Solomonov, Inna; Hanuna, Assaf; Divinsky, Yalin; Shmueli, Merav D.; Hezroni, Hadas; Zaretsky, Irina; Mor, Michael; Golani, Ofra; Sabah, Gad; Jakobson-Setton, Ariella; Yanichkin, Natalia; Feinmesser, Meora; Tsoref, Daliah; Salman, Lina; Yeoshoua, Effi; Peretz, Eyal; Erlich, Inna; Cohen, Netta Mendelson; Gershoni, Jonathan M.; [...]

Tumor-reactive antibodies evolve from non-binding and autoreactive precursors

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Elsevier BV, 2022

Published in: Cell, 185 (2022) 7, Seite 1208-1222.e21
Zheng, Danping; Mohapatra, Gayatree; Kern, Lara; He, Yiming; Shmueli, Merav D.; Valdés-Mas, Rafael; Kolodziejczyk, Aleksandra A.; Próchnicki, Tomasz; Vasconcelos, Matilde B.; Schorr, Lena; Hertel, Franziska; Lee, Ye Seul; Rufino, Miguel Camacho; Ceddaha, Emmanuelle; Shimshy, Sandy; Hodgetts, Ryan James; Dori-Bachash, Mally; Kleimeyer, Christian; Goldenberg, Kim; Heinemann, Melina; Stettner, Noa; Harmelin, Alon; Shapiro, Hagit; Puschhof, Jens; [...]

Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation

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Springer Science and Business Media LLC, 2023

Published in: Nature Immunology, 24 (2023) 4, Seite 585-594

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