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Degenhardt, Frauke; Dirmeier, Andrea; Lopez, Rocio; Lang, Sylvia; Kunst, Claudia; Roggenbuck, Dirk; Reinhold, Dirk; Szymczak, Silke; Rogler, Gerhard; Klebl, Frank; Franke, Andre; Rieder, Florian

Serologic Anti-GP2 Antibodies Are Associated with Genetic Polymorphisms, Fibrostenosis, and Need for Surgical Resection in Crohnʼs Disease

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Oxford University Press (OUP), 2016

Published in: Inflammatory Bowel Diseases, 22 (2016) 11, Seite 2648-2657
Silva, Nayane S. B.; Bourguiba‐Hachemi, Sonia; Douillard, Venceslas; Koskela, Satu; Degenhardt, Frauke; Clancy, Jonna; Limou, Sophie; Meyer, Diogo; Masotti, Cibele; Knorst, Stefan; Naslavsky, Michel Satya; Franke, Andre; Castelli, Erick C.; Gourraud, Pierre‐Antoine; Vince, Nicolas

18th International HLA and Immunogenetics Workshop: Report on the SNP‐HLA Reference Consortium (SHLARC) component

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Wiley, 2024

Published in: HLA, 103 (2024) 1
Lin, Shiqi; Gao, Xingjian; Degenhardt, Frauke; Qian, Yu; Liu, Tianzi; Ramon, Xavier Farre; Hadi, Syed Sibte; Romero-Gómez, Manuel; Fernández, Javier; Albillos, Agustín; Ferret, Maria Buti; Bujanda, Luis; Julià, Antonio; de Cid, Rafael; Asselta, Rosanna; Franke, Andre; Liu, Fan

Genome-wide epistasis study highlights genetic interactions influencing severity of COVID-19

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Springer Science and Business Media LLC, 2023

Published in: European Journal of Epidemiology, 38 (2023) 8, Seite 883-889
Moitinho-Silva, Lucas; Degenhardt, Frauke; Rodriguez, Elke; Emmert, Hila; Juzenas, Simonas; Möbus, Lena; Uellendahl-Werth, Florian; Sander, Nicole; Baurecht, Hansjörg; Tittmann, Lukas; Lieb, Wolfgang; Gieger, Christian; Peters, Annette; Ellinghaus, David; Bang, Corinna; Franke, Andre; Weidinger, Stephan; Rühlemann, Malte Christoph

Host genetic factors related to innate immunity, environmental sensing and cellular functions are associated with human skin microbiota

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Springer Science and Business Media LLC, 2022

Published in: Nature Communications, 13 (2022) 1
Rühlemann, Malte C.; Degenhardt, Frauke; Thingholm, Louise B.; Wang, Jun; Skiecevičienė, Jurgita; Rausch, Philipp; Hov, Johannes R.; Lieb, Wolfgang; Karlsen, Tom H.; Laudes, Matthias; Baines, John F.; Heinsen, Femke-Anouska; Franke, Andre

Application of the distance-based F test in an mGWAS investigating β diversity of intestinal microbiota identifies variants in SLC9A8 (NHE8) and 3 other loci

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Informa UK Limited, 2018

Published in: Gut Microbes, 9 (2018) 1, Seite 68-75
Yadav, Pankaj; Ellinghaus, David; Rémy, Gaëlle; Freitag-Wolf, Sandra; Cesaro, Anabelle; Degenhardt, Frauke; Boucher, Gabrielle; Delacre, Myriam; Peyrin-Biroulet, Laurent; Pichavant, Muriel; Rioux, John D.; Gosset, Philippe; Franke, Andre; Schumm, L. Philip; Krawczak, Michael; Chamaillard, Mathias; Dempfle, Astrid; Andersen, Vibeke

Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice

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Elsevier BV, 2017

Published in: Gastroenterology, 153 (2017) 2, Seite 550-565
Hammer, Quirin; Dunst, Josefine; Christ, Wanda; Picarazzi, Francesca; Wendorff, Mareike; Momayyezi, Pouria; Huhn, Oisín; Netskar, Herman K.; Maleki, Kimia T.; García, Marina; Sekine, Takuya; Sohlberg, Ebba; Azzimato, Valerio; Aouadi, Myriam; Degenhardt, Frauke; Franke, Andre; Spallotta, Francesco; Mori, Mattia; Michaëlsson, Jakob; Björkström, Niklas K.; Rückert, Timo; Romagnani, Chiara; Horowitz, Amir; Klingström, Jonas; [...]

SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells

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Elsevier BV, 2022

Published in: Cell Reports, 38 (2022) 10, Seite 110503
Stuart, Philip E.; Tsoi, Lam C.; Nair, Rajan P.; Ghosh, Manju; Kabra, Madhulika; Shaiq, Pakeeza A.; Raja, Ghazala K.; Qamar, Raheel; Thelma, B.K.; Patrick, Matthew T.; Parihar, Anita; Singh, Sonam; Khandpur, Sujay; Kumar, Uma; Wittig, Michael; Degenhardt, Frauke; Tejasvi, Trilokraj; Voorhees, John J.; Weidinger, Stephan; Franke, Andre; Abecasis, Goncalo R.; Sharma, Vinod K.; Elder, James T.

Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine mapping in the MHC and genome wide

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Elsevier BV, 2022

Published in: Human Genetics and Genomics Advances, 3 (2022) 1, Seite 100069
Rühlemann, Malte Christoph; Hermes, Britt Marie; Bang, Corinna; Doms, Shauni; Moitinho-Silva, Lucas; Thingholm, Louise Bruun; Frost, Fabian; Degenhardt, Frauke; Wittig, Michael; Kässens, Jan; Weiss, Frank Ulrich; Peters, Annette; Neuhaus, Klaus; Völker, Uwe; Völzke, Henry; Homuth, Georg; Weiss, Stefan; Grallert, Harald; Laudes, Matthias; Lieb, Wolfgang; Haller, Dirk; Lerch, Markus M.; Baines, John F.; Franke, Andre

Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome

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Springer Science and Business Media LLC, 2021

Published in: Nature Genetics, 53 (2021) 2, Seite 147-155
Tsoi, Lam C.; Rodriguez, Elke; Degenhardt, Frauke; Baurecht, Hansjörg; Wehkamp, Ulrike; Volks, Natalie; Szymczak, Silke; Swindell, William R.; Sarkar, Mrinal K.; Raja, Kalpana; Shao, Shuai; Patrick, Matthew; Gao, Yilin; Uppala, Ranjitha; Perez White, Bethany E; Getsios, Spiro; Harms, Paul W.; Maverakis, Emanual; Elder, James T.; Franke, Andre; Gudjonsson, Johann E.; Weidinger, Stephan

Atopic Dermatitis Is an IL-13–Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis

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Elsevier BV, 2019

Published in: Journal of Investigative Dermatology, 139 (2019) 7, Seite 1480-1489
Kreutzer, Carina; Peters, Sönke; Schulte, Dominik M.; Fangmann, Daniela; Türk, Kathrin; Wolff, Stephan; van Eimeren, Thilo; Ahrens, Markus; Beckmann, Jan; Schafmayer, Clemens; Becker, Thomas; Kerby, Tina; Rohr, Axel; Riedel, Christian; Heinsen, Femke-Anouska; Degenhardt, Frauke; Franke, Andre; Rosenstiel, Philip; Zubek, Nana; Henning, Christian; Freitag-Wolf, Sandra; Dempfle, Astrid; Psilopanagioti, Aristea; Petrou-Papadaki, Helen; [...]

Hypothalamic Inflammation in Human Obesity Is Mediated by Environmental and Genetic Factors

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American Diabetes Association, 2017

Published in: Diabetes, 66 (2017) 9, Seite 2407-2415
Schmitt, Jochen; Schwarz, Kristin; Baurecht, Hansjörg; Hotze, Melanie; Fölster-Holst, Regina; Rodríguez, Elke; Lee, Young A.E.; Franke, Andre; Degenhardt, Frauke; Lieb, Wolfgang; Gieger, Christian; Kabesch, Michael; Nöthen, Markus M.; Irvine, Alan D.; McLean, W.H. Irwin; Deckert, Stefanie; Stephan, Victoria; Schwarz, Peter; Aringer, Martin; Novak, Natalija; Weidinger, Stephan

Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes

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Elsevier BV, 2016

Published in: Journal of Allergy and Clinical Immunology, 137 (2016) 1, Seite 130-136
Zecher, Britta F; Ellinghaus, David; Schloer, Sebastian; Niehrs, Annika; Padoan, Benedetta; Baumdick, Martin E; Yuki, Yuko; Martin, Maureen P; Glow, Dawid; Schröder-Schwarz, Jennifer; Niersch, Jennifer; Brias, Sébastien; Müller, Luisa M; Habermann, Robin; Kretschmer, Paul; Früh, Tristan; Dänekas, Janis; Wehmeyer, Malte H; Poch, Tobias; Sebode, Marcial; Ellinghaus, Eva; Degenhardt, Frauke; Körner, Christian; Hoelzemer, Angelique; [...]

HLA-DPA1*02:01~B1*01:01is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells

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BMJ, 2024

Published in: Gut, 73 (2024) 2, Seite 325-337
Rosati, Elisa; Rios Martini, Gabriela; Pogorelyy, Mikhail V; Minervina, Anastasia A; Degenhardt, Frauke; Wendorff, Mareike; Sari, Soner; Mayr, Gabriele; Fazio, Antonella; Dowds, Christel Marie; Hauser, Charlotte; Tran, Florian; von Schönfels, Witigo; Pochhammer, Julius; Salnikova, Maria A; Jaeckel, Charlot; Gigla, Johannes Boy; Sabet, Sanaz Sedghpour; Hübenthal, Matthias; Schiminsky, Esther; Schreiber, Stefan; Rosenstiel, Philip C; Scheffold, Alexander; Thomas, Paul G; [...]

A novel unconventional T cell population enriched in Crohn’s disease

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BMJ, 2022

Published in: Gut, 71 (2022) 11, Seite 2194-2204
Degenhardt, Frauke; Wendorff, Mareike; Wittig, Michael; Ellinghaus, Eva; Datta, Lisa W; Schembri, John; Ng, Siew C; Rosati, Elisa; Hübenthal, Matthias; Ellinghaus, David; Jung, Eun Suk; Lieb, Wolfgang; Abedian, Shifteh; Malekzadeh, Reza; Cheon, Jae Hee; Ellul, Pierre; Sood, Ajit; Midha, Vandana; Thelma, B K; Wong, Sunny H; Schreiber, Stefan; Yamazaki, Keiko; Kubo, Michiaki; Boucher, Gabrielle; [...]

Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles

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Oxford University Press (OUP), 2019

Published in: Human Molecular Genetics, 28 (2019) 12, Seite 2078-2092
Gassner, Christoph; Degenhardt, Frauke; Meyer, Stefan; Vollmert, Caren; Trost, Nadine; Neuenschwander, Kathrin; Merki, Yvonne; Portmann, Claudia; Sigurdardottir, Sonja; Zorbas, Antigoni; Engström, Charlotte; Gottschalk, Jochen; Amar el Dusouqui, Soraya; Waldvogel-Abramovski, Sophie; Rigal, Emmanuel; Tissot, Jean-Daniel; Tinguely, Caroline; Mauvais, Simon M.; Sarraj, Amira; Bessero, Daniel; Stalder, Michele; Infanti, Laura; Buser, Andreas; Sigle, Jörg; [...]

Low-Frequency Blood Group Antigens in Switzerland

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S. Karger AG, 2018

Published in: Transfusion Medicine and Hemotherapy, 45 (2018) 4, Seite 239-250
Tedbury, Philip R.; Manfredi, Candela; Degenhardt, Frauke; Conway, Joseph; Horwath, Michael C.; McCracken, Courtney; Sorscher, Adam J.; Moreau, Sandy; Wright, Christine; Edwards, Carolina; Brewer, Jo; Guarner, Jeannette; de Wit, Emmie; Williamson, Brandi N.; Suthar, Mehul S.; Ong, Yee T.; Roback, John D.; Alter, David N.; Holter, Jan C.; Karlsen, Tom H.; Sacchi, Nicoletta; Romero‐Gómez, Manuel; Invernizzi, Pietro; Fernández, Javier; [...]

Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS‐CoV‐2 infection and COVID‐19 disease severity

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Wiley, 2023

Published in: The FASEB Journal, 37 (2023) 11
Cappadona, Claudio; Paraboschi, Elvezia Maria; Ziliotto, Nicole; Bottaro, Sandro; Rimoldi, Valeria; Gerussi, Alessio; Azimonti, Andrea; Brenna, Daniele; Brunati, Andrea; Cameroni, Charlotte; Campanaro, Giovanni; Carloni, Francesca; Cavadini, Giacomo; Ciravegna, Martina; Composto, Antonio; Converso, Giuseppe; Corbella, Pierluigi; D’Eugenio, Davide; Dal Rì, Giovanna; Di Giorgio, Sofia Maria; Grondelli, Maria Chiara; Guerrera, Lorenza; Laffoucriere, Georges; Lando, Beatrice; [...]

MEDTEC Students against Coronavirus: Investigating the Role of Hemostatic Genes in the Predisposition to COVID-19 Severity

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MDPI AG, 2021

Published in: Journal of Personalized Medicine, 11 (2021) 11, Seite 1166
Lett, Tristram A; Vogel, Bob O; Ripke, Stephan; Wackerhagen, Carolin; Erk, Susanne; Awasthi, Swapnil; Trubetskoy, Vassily; Brandl, Eva J; Mohnke, Sebastian; Veer, Ilya M; Nöthen, Markus M; Rietschel, Marcella; Degenhardt, Franziska; Romanczuk-Seiferth, Nina; Witt, Stephanie H; Banaschewski, Tobias; Bokde, Arun L W; Büchel, Christian; Quinlan, Erin B; Desrivières, Sylvane; Flor, Herta; Frouin, Vincent; Garavan, Hugh; Gowland, Penny; [...]

Cortical Surfaces Mediate the Relationship Between Polygenic Scores for Intelligence and General Intelligence

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Oxford University Press (OUP), 2020

Published in: Cerebral Cortex, 30 (2020) 4, Seite 2708-2719
Mucha, Sören; Baurecht, Hansjörg; Novak, Natalija; Rodríguez, Elke; Bej, Saptarshi; Mayr, Gabriele; Emmert, Hila; Stölzl, Dora; Gerdes, Sascha; Jung, Eun Suk; Degenhardt, Frauke; Hübenthal, Matthias; Ellinghaus, Eva; Kässens, Jan Christian; Wienbrandt, Lars; Lieb, Wolfgang; Müller-Nurasyid, Martina; Hotze, Melanie; Dand, Nick; Grosche, Sarah; Marenholz, Ingo; Arnold, Andreas; Homuth, Georg; Schmidt, Carsten O.; [...]

Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression

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Elsevier BV, 2020

Published in: Journal of Allergy and Clinical Immunology, 145 (2020) 4, Seite 1208-1218

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