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Bornhauser, Beat C.; Boutter, Jeannette; Horvath, Peter; Stanulla, Martin; Bourquin, Jean-Pierre

Abstract 4597: Stroma-derived Basigin controls survival of leukemia cells through regulation of their redox state

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American Association for Cancer Research (AACR), 2013

Published in: Cancer Research
Bornhauser, Beat C; Boutter, Jeannette; Horvath, Peter; Stanulla, Martin; Bourquin, Jean-Pierre

Image-Based RNA Interference Screening Identifies Microenvironmental Signals Supporting Primary Acute Lymphoblastic Leukemia Cell Survival

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American Society of Hematology, 2012

Published in: Blood
Zuellig, Richard A.; Bornhauser, Beat C.; Amstutz, Ralf; Constantin, Bruno; Schaub, Marcus C.

Tissue Expression and Actin Binding of a Novel N-Terminal Utrophin Isoform

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Hindawi Limited, 2011

Published in: Journal of Biomedicine and Biotechnology
Sippel, Maria; Rajala, Raili; Korhonen, Laura; Bornhauser, Beat; Sokka, Anna-Leena; Naito, Mikihiko; Lindholm, Dan

Dexamethasone regulates expression of BRUCE/Apollon and the proliferation of neural progenitor cells

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Wiley, 2009

Published in: FEBS Letters
Nagano, Kohji; Bornhauser, Beat C; Warnasuriya, Gayathri; Entwistle, Alan; Cramer, Rainer; Lindholm, Dan; Naaby-Hansen, Soren

PDGF regulates the actin cytoskeleton through hnRNP-K-mediated activation of the ubiquitin E3-ligase MIR

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Springer Science and Business Media LLC, 2006

Published in: The EMBO Journal
Knuesel, Irene; Bornhauser, Beat C.; Zuellig, Richard A.; Heller, Franziska; Schaub, Marcus C.; Fritschy, Jean-Marc

Differential expression of utrophin and dystrophin in CNS neurons: An in situ hybridization and immunohistochemical study

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Wiley, 2000

Published in: The Journal of Comparative Neurology
Zuellig, Richard A.; Bornhauser, Beat C.; Knuesel, Irene; Heller, Franziska; Fritschy, Jean-Marc; Schaub, Marcus C.

Identification and characterisation of transcript and protein of a new short N-terminal utrophin isoform

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Wiley, 2000

Published in: Journal of Cellular Biochemistry
Knuesel, Irene; Mastrocola, Mario; Zuellig, Richard A.; Bornhauser, Beat; Schaub, Marcus C.; Fritschy, Jean‐Marc

Altered synaptic clustering of GABAA receptors in mice lacking dystrophin (mdx mice)

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Wiley, 1999

Published in: European Journal of Neuroscience
Gökçe, Furkan; Kaestli, Alicia; Lohasz, Christian; de Geus, Martina; Kaltenbach, Hans‐Michael; Renggli, Kasper; Bornhauser, Beat; Hierlemann, Andreas; Modena, Mario

Microphysiological Drug‐Testing Platform for Identifying Responses to Prodrug Treatment in Primary Leukemia

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Wiley, 2023

Published in: Advanced Healthcare Materials
Besse, Lenka; Besse, Andrej; Kraus, Marianne; Maurits, Elmer; Overkleeft, Herman S.; Bornhauser, Beat; Bourquin, Jean-Pierre; Driessen, Christoph

High Immunoproteasome Activity and sXBP1 in Pediatric Precursor B-ALL Predicts Sensitivity towards Proteasome Inhibitors

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MDPI AG, 2021

Published in: Cells
Aguadé-Gorgorió, Júlia; McComb, Scott; Cario, Gunnar; Stanulla, Martin; Eckert, Cornelia; Bourquin, Jean-Pierre; Bornhauser, Beat C.

Abstract 3548: In vivo CRISPR reveals dual activation of apoptosis and necroptosis as means to eradicate drug resistant leukemia

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American Association for Cancer Research (AACR), 2016

Published in: Cancer Research
Bornhauser, Beat; Mirkowska, Paulina; Hofmann, Andreas; Schmitz, Maike; Stanulla, Martin; Cario, Gunnar; Schrappe, Martin; Wollscheid, Bernd; Bourquin, Jean-Pierre

Abstract 4358: Analysis of the cell surface proteome for the identification of candidate diagnostic and therapeutic targets in drug resistant childhood acute lymphoblastic leukemia (ALL)

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American Association for Cancer Research (AACR), 2010

Published in: Cancer Research
Bonapace, Laura; Bornhauser, Beat C.; Schmitz, Maike; Cario, Gunnar; Ziegler, Urs; Niggli, Felix K.; Schäfer, Beat W.; Schrappe, Martin; Stanulla, Martin; Bourquin, Jean-Pierre

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

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American Society for Clinical Investigation, 2010

Published in: Journal of Clinical Investigation
Bornhauser, Beat C.; Bonapace, Laura; Lindholm, Dan; Martinez, Rodrigo; Cario, Gunnar; Schrappe, Martin; Niggli, Felix K.; Schäfer, Beat W.; Bourquin, Jean-Pierre

Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway

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American Society of Hematology, 2007

Published in: Blood
Sidhu, Jasmeet; Steffen, Fabio D.; Jimenez, Iria Anne; Huang, Yun; Rauwolf, Kerstin K.; Chakraborty, Arijit; Krishnan, Shekhar; Saha, Vaskar; Bornhauser, Beat; Bourquin, Jean-Pierre

Phenotypic Drug Response Profiling Identifies Asparaginase-Based Synergistic Combinations for Very High Risk Acute Lymphoblastic Leukaemia

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American Society of Hematology, 2023

Published in: Blood
Hinze, Laura; Schreek, Sabine; Zeug, Andre; Ponimaskin, Evgeni; Labrosse, Roxane; Degar, James; Bornhauser, Beat; Bourquin, Jean-Pierre; Stanulla, Martin; Gutierrez, Alejandro

Abstract PR06: Spatial sequestration of GSKα as a cellular response to amino acid starvation

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American Association for Cancer Research (AACR), 2020

Published in: Cancer Research
McComb, Scott; Chan, Pik Ki; Guinot, Anna; Hartmannsdottir, Holmfridur; Jenni, Silvia; Dobay, Maria Pamela; Bourquin, Jean-Pierre; Bornhauser, Beat C.

Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7

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American Association for the Advancement of Science (AAAS), 2019

Published in: Science Advances
Bhansali, Rahul S.; Rammohan, Malini; Lee, Ji Heon Paul; Malinge, Sebastien; Tsai, Yi-Chien; Hijiya, Nobuko; Bornhauser, Beat; Bourquin, Jean-Pierre; Fruit, Corinne; Besson, Thierry; Crispino, John D.

The Chromosome 21 Kinase DYRK1A and Its Substrate FOXO1 Constitute a Novel Therapeutic Pathway in B-ALL

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American Society of Hematology, 2018

Published in: Blood
Vogiatzi, Fotini; Heymann, Julia; Rösner, Thies; Lenk, Lennart; Cario, Gunnar; Schrappe, Martin; Bornhauser, Beat; Bourquin, Jean-Pierre; Bomken, Simon; Valerius, Thomas; Peipp, Matthias; Kellner, Christian; Schewe, Denis Martin

Venetoclax Enhances the Efficacy of Therapeutic Antibodies in B-Cell Malignancies

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American Society of Hematology, 2018

Published in: Blood
Aguadé-Gorgorio, Julia; McComb, Scott; Eckert, Cornelia; Dobay, Maria Pamela; Cario, Gunnar; Mezzatesta, Caterina; Stackelberg, Arend Von; Stanulla, Martin; Martin, Schrappe; Bourquin, Jean-Pierre; Bornhauser, Beat C.

Abstract 4321: TNF receptor 2 is essential for RIP1-dependent cell death in refractory leukemia

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American Association for Cancer Research (AACR), 2017

Published in: Cancer Research

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