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Marks, David I; Moorman, Anthony V; Chilton, Lucy; Paietta, Elisabeth; de Wald, Gordon; Fielding, Adele K; Goldstone, Anthony H.; Litzow, Mark R; Luger, Selina M.; McMillan, Andrew; Rowe, Jacob M.; Tallman, Martin S; Lazarus, Hillard M.

Biology and Outcome of 85 Adults with Acute Lymphoblastic Leukemia (ALL) with t(4;11)/MLL-AF4 Treated in the UKALL XII/ECOG 2993 Study

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American Society of Hematology, 2012

Published in: Blood
Sive, Jonathan I.; Buck, Georgina; Fielding, Adele; Lazarus, Hillard M.; Litzow, Mark R.; Luger, Selina; Marks, David I.; McMillan, Andrew; Moorman, Anthony V.; Richards, Susan M.; Rowe, Jacob M.; Tallman, Martin S.; Goldstone, Anthony H.

Outcomes in older adults with acute lymphoblastic leukaemia (ALL): results from the international MRC UKALL XII/ECOG2993 trial

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Wiley, 2012

Published in: British Journal of Haematology
Fielding, Adele K.; Buck, Georgina; Lazarus, Hillard M.; Litzow, Mark R.; Luger, Selina; Marks, David I.; McMillan, Andrew; Moorman, Anthony V.; Paietta, Elisabeth; Richards, Susan M; Tallman, Martin S.; Rowe, Jacob M.; Goldstone, Anthony H.

Imatinib Significantly Enhances Long-Term Outcomes In Philadelphia Positive Acute Lymphoblastic Leukaemia; Final Results of the UKALLXII/ECOG2993 Trial

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American Society of Hematology, 2010

Published in: Blood
Sive, Jonathan I; Buck, Georgina; Fielding, Adele; Lazarus, Hillard M.; Litzow, Mark R.; Luger, Selina; Marks, David I.; McMillan, Andrew; Richards, Susan M; Rowe, Jacob M.; Tallman, Martin S.; Goldstone, Anthony H.

Inability to Tolerate Standard Therapy Is a Major Reason for Poor Outcome In Older Adults with Acute Lymphoblastic Leukemia (ALL): Results From the International MRC/ECOG Trial

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American Society of Hematology, 2010

Published in: Blood
Litzow, Mark R.; Buck, Georgina; Dewald, Gordon; Fielding, Adele; Ketterling, Rhett; Lazarus, Hillard M.; Luger, Selina; Marks, David I.; McMillan, Andrew; Moorman, Anthony V.; Paietta, Elisabeth; Richards, Susan M; Rowe, Jacob M.; Tallman, Martin S.; Goldstone, Anthony H.

Outcome of 1,229 Adult Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia (B-ALL) Patients (pts) From the International UKALLXII/E2993 Trial: No Difference In Results Between B Cell Immunophenotypic Subgroups

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American Society of Hematology, 2010

Published in: Blood
Mansour, Marc R; Sulis, Maria Luisa; Duke, Veronique; Foroni, Letizia; Jenkinson, Sarah; Allen, Christopher G; Gale, Rosemary E; Buck, Georgina; Richards, Sue; Paietta, Elisabeth; Tallman, Martin; Goldstone, Anthony H; Rowe, Jacob M.; Ferrando, Adolfo A.; Linch, David C

Unlike Paediatric T-ALL, Notch-1 and FBXW7 Mutations Do Not Seem to Predict a Better Outcome in Adult Patients: Data from the UKALLXII/ECOG2993 Protocol

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American Society of Hematology, 2008

Published in: Blood
Fielding, Adele K.; Richards, Susan M.; Lazarus, Hillard M.; Litzow, Mark R.; Luger, Selina M.; Marks, David I.; McMillan, Andrew K.; Rowe, Jacob M.; Tallman, Martin S.; Goldstone, Anthony H.

Does Imatinib Change the Outcome in Philapdelphia Chromosome Positive Acute Lymphoblastic Leukaemia in Adults? Data from the UKALLXII/ECOG2993 Study

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American Society of Hematology, 2007

Published in: Blood
Rowe, Jacob M.; Buck, Georgina; Fielding, Adele; Tallman, Martin S.; Burnett, Alan K.; Chopra, Raj; Wiernik, Peter H.; Richards, Susan M.; Lazarus, Hillard M.; Foroni, Letizia; Paietta, Elisabeth; Litzow, Mark R.; Marks, David; Durrant, Jill; Goldstone, Anthony H.

In Adults with Standard-Risk Acute Lymphoblastic Leukemia (ALL) the Greatest Benefit Is Achieved from an Allogeneic Transplant in First Complete Remission (CR) and an Autologous Transplant Is Less Effective Than Conventional Consolidation/Maintenance Chemotherapy: Final Results of the International ALL Trial (MRC UKALL XII/ECOG E2993)

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American Society of Hematology, 2006

Published in: Blood
Lazarus, Hillard M.; Richards, Sue M.; Chopra, Raj; Litzow, Mark R.; Burnett, Alan K.; Wiernik, Peter H.; Franklin, Ian M.; Tallman, Martin S.; Buck, G.; Durrant, Jill; Rowe, Jacob M.; Goldstone, Anthony H.

Adult Patients with Acute Lymphoblastic Leukemia (ALL) and Central Nervous System (CNS) Leukemia at Diagnosis May Attain Durable Complete Remissions (CR). Results from the International ALL Trial (MRC UKALL-XII/ECOG E2993)

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American Society of Hematology, 2004

Published in: Blood
Goldstone, Anthony H.; Lazarus, Hillard J.; Richards, Sue M.; Litzow, Mark R.; Chopra, Raj; Burnett, Alan; Wiernik, Peter H.; Franklin, Ian M.; Prentice, H. G.; Tallman, Martin; Harrison, G.; Durrant, Jill; Rowe, Jacob

The Outcome of 551 1st CR Transplants in Adult ALL from the UKALL XII/ECOG 2993 Study

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American Society of Hematology, 2004

Published in: Blood
Ganzel, Chezi; Wang, Xin V.; Rowe, Jacob M.; Richards, Susan M.; Buck, Georgina; Marks, David I.; Litzow, Mark R.; Paietta, Elisabeth M.; Foroni, Letizia; Luger, Selina M.; Willman, Cheryl L.; Mullighan, Charles G.; Roberts, Kathryn G.; Wiernik, Peter H.; Douer, Dan; Lazarus, Hillard M.; Tallman, Martin S.; Goldstone, Anthony H.

At three years, patients with acute lymphoblastic leukaemia are still at risk for relapse. Results of the international MRC UKALLXII/ECOG E2993 trial

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Wiley, 2020

Published in: British Journal of Haematology
Ganzel, Chezi; Xin Victoria, Wang; Fielding, Adele K.; Rowe, Jacob M.; Richards, Susan M; Buck, Georgina; Chopra, Rajesh; Durrant, I. Jill; Marks, David; Franklin, Ian M.; McMilan, Andrew K; Litzow, Mark R; Paietta, Elisabeth; Luger, Selina; Wiernik, Peter H; Douer, Dan; Lazarus, Hillard M.; Tallman, Martin S; Goldstone, Anthony H.

in Philadelphia-Chromosome-Negative Acute Lymphoblastic Leukemia, Late Relapses Are Not Uncommon, Occur Mostly in Patients at Standard Risk and Have a Relatively Favorable Outcome. Results of the International ALL Trial: MRC Ukallxii/ECOG E2993

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American Society of Hematology, 2015

Published in: Blood
Rapaport, Franck; Patel, Jay; He, Jie; Brennan, Timothy A; Nahas, Michelle; Balassubramanian, Sohail; Otto, Geoff; Lipson, Doron; Stephens, Phil; Miller, Vincent A.; Racevskis, Janis; Litzow, Mark R; Wiernik, Peter H.; Goldstone, Anthony H.; Luger, Selina; van den Brink, Marcel; Viale, Agnes; Rowe, Jacob M.; Tallman, Martin S.; Melnick, Ari; Paietta, Elisabeth; Gonen, Mithat; Levine, Ross L.

Integrated DNA/RNA Profiling for Somatic Alterations in Adult B-Cell ALL

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American Society of Hematology, 2015

Published in: Blood
Mansour, Marc R.; Sulis, Maria L.; Duke, Veronique; Foroni, Letizia; Jenkinson, Sarah; Koo, Kenneth; Allen, Christopher G.; Gale, Rosemary E.; Buck, Georgina; Richards, Sue; Paietta, Elisabeth; Rowe, Jacob M.; Tallman, Martin S.; Goldstone, Anthony H.; Ferrando, Adolfo A.; Linch, David C.

Prognostic Implications of NOTCH1 and FBXW7 Mutations in Adults With T-Cell Acute Lymphoblastic Leukemia Treated on the MRC UKALLXII/ECOG E2993 Protocol

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American Society of Clinical Oncology (ASCO), 2009

Published in: Journal of Clinical Oncology
Fielding, Adele K.; Rowe, Jacob M.; Richards, Susan M.; Buck, Georgina; Moorman, Anthony V.; Durrant, I. Jill; Marks, David I.; McMillan, Andrew K.; Litzow, Mark R.; Lazarus, Hillard M.; Foroni, Letizia; Dewald, Gordon; Franklin, Ian M.; Luger, Selina M.; Paietta, Elisabeth; Wiernik, Peter H.; Tallman, Martin S.; Goldstone, Anthony H.

Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome–positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International ALL Trial MRC UKALLXII/ECOG2993

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American Society of Hematology, 2009

Published in: Blood
Marks, David I.; Paietta, Elisabeth M.; Moorman, Anthony V.; Richards, Susan M.; Buck, Georgina; DeWald, Gordon; Ferrando, Adolfo; Fielding, Adele K.; Goldstone, Anthony H.; Ketterling, Rhett P.; Litzow, Mark R.; Luger, Selina M.; McMillan, Andrew K.; Mansour, Marc R.; Rowe, Jacob M.; Tallman, Martin S.; Lazarus, Hillard M.

T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)

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American Society of Hematology, 2009

Published in: Blood
Tosello, Valeria; Mansour, Marc R.; Barnes, Kelly; Paganin, Maddalena; Sulis, Maria Luisa; Jenkinson, Sarah; Allen, Christopher G.; Gale, Rosemary E.; Linch, David C.; Palomero, Teresa; Real, Pedro; Murty, Vundavalli; Yao, Xiaopan; Richards, Susan M.; Goldstone, Anthony; Rowe, Jacob; Basso, Giuseppe; Wiernik, Peter H.; Paietta, Elisabeth; Pieters, Rob; Horstmann, Martin; Meijerink, Jules P. P.; Ferrando, Adolfo A.

WT1 mutations in T-ALL

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American Society of Hematology, 2009

Published in: Blood
Goldstone, Anthony H.; Richards, Susan M.; Lazarus, Hillard M.; Tallman, Martin S.; Buck, Georgina; Fielding, Adele K.; Burnett, Alan K.; Chopra, Raj; Wiernik, Peter H.; Foroni, Letizia; Paietta, Elisabeth; Litzow, Mark R.; Marks, David I.; Durrant, Jill; McMillan, Andrew; Franklin, Ian M.; Luger, Selina; Ciobanu, Niculae; Rowe, Jacob M.

In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: final results of the International ALL Trial (MRC UKALL XII/ECOG E2993)

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American Society of Hematology, 2008

Published in: Blood
Rowe, Jacob M.; Buck, Georgina; Moorman, Anthony V; Tallman, Martin S; Richards, Susan M; Fielding, Adele K; Burnett, Alan K.; Franklin, Ian M; Wiernik, Peter H.; Lazarus, Hillard M; Paietta, Elisabeth; Litzow, Mark R.; Marks, David I; Luger, Selina; Dewald, Gordon W.; Goldstone, Anthony H.

Standard Consolidation/Maintenance Chemotherapy Is Consistently Superior to a Single Autologous Transplant for Adult Patients with Acute Lymphoblastic Leukemia: Results of the International ALL Trial (MRC UKALL XII/ECOG E2993)

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American Society of Hematology, 2008

Published in: Blood
Moorman, Anthony V.; Harrison, Christine J.; Buck, Georgina A. N.; Richards, Sue M.; Secker-Walker, Lorna M.; Martineau, Mary; Vance, Gail H.; Cherry, Athena M.; Higgins, Rodney R.; Fielding, Adele K.; Foroni, Letizia; Paietta, Elisabeth; Tallman, Martin S.; Litzow, Mark R.; Wiernik, Peter H.; Rowe, Jacob M.; Goldstone, Anthony H.; Dewald, Gordon W.

Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial

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American Society of Hematology, 2007

Published in: Blood

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