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Mancke, Falk; Queisser, Angela; Kunert, Heike; Heeg, Steffen; Hirt, Nina; Götschel, Frank; Hecht, Andreas; Artandi, Steve; Opitz, Oliver G.

S1992 The Interaction of β-Catenin and Telomerase and Its Role During Carcinogenesis

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Elsevier BV, 2009

Published in: Gastroenterology
Monasterio, Carmen; Schauer, Franziska; Kern, Johannes S.; Technau-Hafsi, Kristin; Lazaro, Adhara; Heeg, Steffen; Deibert, Peter; Schmidt, Arthur; kuellmer, Armin; Schmitt-Graeff, Annette; Kreisel, Wolfgang

Mo1134 – Esophageal Lichen Planus: Diagnostic Criteria and Therapeutic Approaches of an Underdiagnosed Disease. A Survey in 52 Patients

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Elsevier BV, 2019

Published in: Gastroenterology
Das, Koushik K.; Heeg, Steffen; Pitarresi, Jason R.; Reichert, Maximilian; Bakir, Basil; Takano, Shigetsugu; Kopp, Janel L.; Wahl‐Feuerstein, Anja; Hicks, Philip; Sander, Maike; Rustgi, Anil K.

ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis

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Wiley, 2018

Published in: Developmental Dynamics
Takano, Shigetsugu; Reichert, Maximilian; Yoshitomi, Hideyuki; Bakir, Basil; Das, Koushik K.; Heeg, Steffen; Kagawa, Shingo; Shimizu, Hiroaki; Ohtsuka, Masayuki; Furukawa, Katsunori; Miyazaki, Masaru; Rustgi, Anil K.

Abstract B30: Prrx1 isoforms regulate pancreatic cancer stem cell functions during pancreatic cancer progression

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American Association for Cancer Research (AACR), 2016

Published in: Cancer Research
Takano, Shigetsugu; Reichert, Maximilian; Bakir, Basil; Das, Koushik K.; Nishida, Takahiro; Miyazaki, Masaru; Heeg, Steffen; Collins, Meredith A.; Marchand, Benoît; Hicks, Philip D.; Maitra, Anirban; Rustgi, Anil K.

Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization

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Cold Spring Harbor Laboratory, 2016

Published in: Genes & Development
Das, Koushik K.; Heeg, Steffen; Reichert, Maximilian; Takano, Shigetsugu; Bakir, Basil S.; Botta, Gregory P.; Hahn, Christopher; Rhim, Andrew D.; Rustgi, Anil K.

Abstract A11: Ets transcription factor Etv5 regulates ductal morphogenesis and differentiation in association with Sox9 in vitro and increases susceptibility and delays recovery from pancreatitis in vivo

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American Association for Cancer Research (AACR), 2015

Published in: Cancer Research
Das, Koushik K.; Heeg, Steffen; Reichert, Maximilian; Takano, Shigetsugu; Bakir, Basil S.; Botta, Gregory P.; Hahn, Christopher; Rhim, Andrew D.; Rustgi, Anil K.

Abstract A46: The Ets-transcription factor Etv1 induces epithelial-mesenchymal transition (EMT) and invasion as well as expands the stromal compartment in vivo

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American Association for Cancer Research (AACR), 2015

Published in: Cancer Research
Heeg, Steffen; Das, Koushik K.; Reichert, Maximilian; Takano, Shigetsugu; Bakir, Basil; Hahn, Christopher; Botta, Gregory P.; Rhim, Andrew D.; Rustgi, Anil K.

53 The ETS-Transcription Factor Etv1 Is an Important Regulator of Pancreatic Carcinogenesis and Invasion

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Elsevier BV, 2014

Published in: Gastroenterology
Takano, Shigetsugu; Reichert, Maximilian; Heeg, Steffen; Bakir, Basil; Das, Koushik K.; Rhim, Andrew D.; Yoshitomi, Hideyuki; Stanger, Ben; Rustgi, Anil K.

Tu1665 Prrx1a and Prrx1b Differentially Regulate Invasion and Metastasis in Pancreatic Cancer

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Elsevier BV, 2014

Published in: Gastroenterology
Heeg, Steffen; Reichert, Maximilian; Takano, Shigetsugu; Wu, Katherine K.; Botta, Gregory P.; Bakir, Basil; Hahn, Christopher; Rhim, Andrew D.; Rustgi, Anil K.

46 The Ets-Transcription Factor Etv1 Induces Invasion and Enhances Self Renewal Capacity in PanIN and Pdac

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Elsevier BV, 2013

Published in: Gastroenterology
Quante, Michael; Heeg, Steffen; von Werder, Alexander; Goessel, Gitta; Fulda, Christine; Doebele, Michaela; Nakagawa, Hiroshi; Beijersbergen, Roderick; Blum, Hubert E.; Opitz, Oliver G.

Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis

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Oxford University Press (OUP), 2005

Published in: Carcinogenesis
Pape, Ulrich-Frank; Kasper, Stefan; Meiler, Johannes; Sinn, Marianne; Vogel, Arndt; Müller, Lothar; Burkhard, Oswald; Caca, Karel; Heeg, Steffen; Büchner-Steudel, Petra; Rodriguez-Laval, Victor; Kühl, Anja A; Arsenic, Ruza; Jansen, Holger; Treasure, Peter; Utku, Nalân

Efficacy and Safety of CAP7.1 as Second-Line Treatment for Advanced Biliary Tract Cancers: Data from a Randomised Phase II Study

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MDPI AG, 2020

Published in: Cancers
Goetze, Thorsten Oliver; Bankstahl, Ulli Simone; Lang, Sven A.; Heeg, Steffen; Bechstein, Wolf Otto; Schnitzbauer, Andreas; Pession, Ursula; Reim, Daniel; Lorenzen, Sylvie; Keck, Tobias; Königsrainer, Alfred; Piso, Pompiliu; Vogel, Arndt; Pauligk, Claudia; Al-Batran, Salah-Eddin

Neoadjuvant chemotherapy with gemcitabine plus cisplatin followed by radical liver resection versus immediate radical liver resection alone with or without adjuvant chemotherapy in incidentally detected gallbladder carcinoma after simple cholecystectomy or in front of radical resection of BTC (ICC/ECC): A phase III study utilizing the German Registry of Incidental Gallbladder Carcinoma Platform (GR)—The AIO/CALGP/ACO-GAIN-Trial

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American Society of Clinical Oncology (ASCO), 2020

Published in: Journal of Clinical Oncology
Pape, Ulrich-Frank; Kasper, Stefan; Meiler, Johannes; Sinn, Marianne; Vogel, Arndt; Mueller, Lothar; Burkhard, Oswald; Caca, Karel; Heeg, Steffen; Laval, Victor Rodriguez; Kühl, Anya A; Arsenic, Ruza; Jansen, Holger; Utku, Nalan

Randomized phase II trial of the carboxylesterase (CES)-converted novel drug EDO-S7.1 in patients (pts) with advanced biliary tract cancers (BTC)

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American Society of Clinical Oncology (ASCO), 2019

Published in: Journal of Clinical Oncology
Heeg, Steffen; Das, Koushik K.; Reichert, Maximilian; Bakir, Basil; Takano, Shigetsugu; Caspers, Julia; Aiello, Nicole M.; Wu, Katherine; Neesse, Albrecht; Maitra, Anirban; Iacobuzio-Donahue, Christine A.; Hicks, Philip; Rustgi, Anil K.

ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer

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Elsevier BV, 2016

Published in: Gastroenterology
Reichert, Maximilian; Takano, Shigetsugu; von Burstin, Johannes; Heeg, Steffen; Kim, Sang-Bae; Lee, Ju-Seog; Hahn, Christopher; Ihida-Stansbury, Kaori; Schneider, Günter; Rhim, Andrew D.; Stanger, Ben; Rustgi, Anil K.

821 The Prrx1 Homeodomain Transcription Factor Plays a Central Role in Pancreatic Regeneration and Carcinogenesis

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Elsevier BV, 2013

Published in: Gastroenterology
Geis, Steffen; Prifert, Christiane; Weissbrich, Benedikt; Lehners, Nicola; Egerer, Gerlinde; Eisenbach, Christoph; Buchholz, Udo; Aichinger, Elisabeth; Dreger, Peter; Neben, Kai; Burkhardt, Ulrich; Ho, Anthony D.; Kräusslich, Hans-Georg; Heeg, Klaus; Schnitzler, Paul

Molecular Characterization of a Respiratory Syncytial Virus Outbreak in a Hematology Unit in Heidelberg, Germany

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American Society for Microbiology, 2013

Published in: Journal of Clinical Microbiology
Reichert, Maximilian; Takano, Shigetsugu; von Burstin, Johannes; Kim, Sang-Bae; Lee, Ju-Seog; Ihida-Stansbury, Kaori; Hahn, Christopher; Heeg, Steffen; Schneider, Günter; Rhim, Andrew D.; Stanger, Ben Z.; Rustgi, Anil K.

The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis

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Cold Spring Harbor Laboratory, 2013

Published in: Genes & Development
Ohashi, Shinya; Naganuma, Seiji; Natsuizaka, Mitsuteru; Kagawa, Shingo; Kinugasa, Hideaki; Subramanian, Harry; Taoka, Naoko; Heeg, Steffen; Ueda, Shugo; Klein-Szanto, Andres J.; Opitz, Oliver G.; Yazumi, Shujiro; Itoh, Hiroshi; Nakagawa, Hiroshi

Sa1787 Regulation of Chemotherapy Resistance Through Epithelial-Mesenchymal Transition by Zinc Finger E-Box-Binding Proteins

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Elsevier BV, 2012

Published in: Gastroenterology
Heeg, Steffen; Hirt, Nina; Queisser, Angela; Schmieg, Hannah; Thaler, Michaela; Kunert, Heike; Quante, Michael; Goessel, Gitta; von Werder, Alexander; Harder, Jan; Beijersbergen, Roderick; Blum, Hubert E.; Nakagawa, Hiroshi; Opitz, Oliver G.

EGFR overexpression induces activation of telomerase via PI3K/AKT‐mediated phosphorylation and transcriptional regulation through Hif1‐alpha in a cellular model of oral–esophageal carcinogenesis

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Wiley, 2011

Published in: Cancer Science

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