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Bruno, Mark; Koschmieder, Julian; Wuest, Florian; Schaub, Patrick; Fehling-Kaschek, Mirjam; Timmer, Jens; Beyer, Peter; Al-Babili, Salim

Corrigendum: Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites

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Oxford University Press (OUP), 2017

Published in: Journal of Experimental Botany
Bruno, Mark; Koschmieder, Julian; Wuest, Florian; Schaub, Patrick; Fehling-Kaschek, Mirjam; Timmer, Jens; Beyer, Peter; Al-Babili, Salim

Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites

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Oxford University Press (OUP), 2016

Published in: Journal of Experimental Botany
Holl, Kristin; Chatain, Nicolas; Krapp, Susanne; Baumeister, Julian; Maié, Tiago; Schmitz, Sarah; Scheufen, Anja; Brock, Nathalie; Koschmieder, Steffen; Moreno-Andrés, Daniel

Calreticulin and JAK2V617F driver mutations induce distinct mitotic defects in myeloproliferative neoplasms

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Springer Science and Business Media LLC, 2024

Published in: Scientific Reports
Chatain, Nicolas; Baumeister, Julian; de Toledo, Marcelo Szymanski; Wong, Dickson W.L.; Gupta, Siddharth; Pannen, Kristina; Junge, Bärbel; Brümmendorf, Tim H.; Boor, Peter; Koschmieder, Steffen

ABL001 (asciminib) Efficiently Targets Transplantable BCR::ABL1 Lymphoid Blast Crisis in the Scl-Tta-p210-BCR::ABL1 Mouse Model

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American Society of Hematology, 2023

Published in: Blood
Bermes, Max; Rodriguez, Maria Jimena; de Toledo, Marcelo Augusto Szymanski; Ernst, Sabrina; Müller-Newen, Gerhard; Brümmendorf, Tim Henrik; Chatain, Nicolas; Koschmieder, Steffen; Baumeister, Julian

Exploiting Synthetic Lethality between Germline BRCA1 Haploinsufficiency and PARP Inhibition in JAK2V617F-Positive Myeloproliferative Neoplasms

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MDPI AG, 2023

Published in: International Journal of Molecular Sciences
Kalmer, Milena; Pannen, Kristina; Lemanzyk, Rebecca; Wirths, Chiara; Baumeister, Julian; Maurer, Angela; Kricheldorf, Kim; Schifflers, Joelle; Gezer, Deniz; Isfort, Susanne; Brümmendorf, Tim H.; Koschmieder, Steffen; Chatain, Nicolas

Clonogenic assays improve determination of variant allele frequency of driver mutations in myeloproliferative neoplasms

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Springer Science and Business Media LLC, 2022

Published in: Annals of Hematology
Koschmieder, Julian; Wüst, Florian; Schaub, Patrick; Álvarez, Daniel; Trautmann, Danika; Krischke, Markus; Rustenholz, Camille; Mano, Jun’ichi; Mueller, Martin J; Bartels, Dorothea; Hugueney, Philippe; Beyer, Peter; Welsch, Ralf

Plant apocarotenoid metabolism utilizes defense mechanisms against reactive carbonyl species and xenobiotics

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Oxford University Press (OUP), 2020

Published in: Plant Physiology
Schubert, Claudia; Allhoff, Manuel; Tillmann, Stefan; Maié, Tiago; Costa, Ivan G.; Lipka, Daniel B.; Schemionek, Mirle; Feldberg, Kristina; Baumeister, Julian; Brümmendorf, Tim H.; Chatain, Nicolas; Koschmieder, Steffen

Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha

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Springer Science and Business Media LLC, 2019

Published in: Journal of Hematology & Oncology
Baumeister, Julian; Chatain, Nicolas; Hubrich, Annika; Küstermann, Caroline; Sontag, Stephanie; Seré, Kristin; Zenke, Martin; Brümmendorf, Tim H; Kranc, Kamil; Koschmieder, Steffen; Gezer, Deniz

Implication of Hypoxia-Inducible Factor-1 (HIF-1) As a New Therapeutic Target in JAK2V617F Positive Myeloproliferative Neoplasms (MPN)

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American Society of Hematology, 2018

Published in: Blood
Gemmecker, Sandra; Schaub, Patrick; Koschmieder, Julian; Brausemann, Anton; Drepper, Friedel; Rodriguez-Franco, Marta; Ghisla, Sandro; Warscheid, Bettina; Einsle, Oliver; Beyer, Peter

Phytoene Desaturase from Oryza sativa: Oligomeric Assembly, Membrane Association and Preliminary 3D-Analysis

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Public Library of Science (PLoS), 2015

Published in: PLOS ONE
Vieri, Margherita; Tharmapalan, Vithurithra; Kalmer, Milena; Baumeister, Julian; Nikolić, Miloš; Schnitker, Matthis; Kirschner, Martin; Flosdorf, Niclas; de Toledo, Marcelo A. S.; Zenke, Martin; Koschmieder, Steffen; Brümmendorf, Tim H.; Beier, Fabian; Wagner, Wolfgang

Cellular aging is accelerated in the malignant clone of myeloproliferative neoplasms

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Springer Science and Business Media LLC, 2023

Published in: Blood Cancer Journal
Baumeister, Julian; Maié, Tiago; Chatain, Nicolas; Gan, Lin; Weinbergerova, Barbora; de Toledo, Marcelo A. S.; Eschweiler, Jörg; Maurer, Angela; Mayer, Jiri; Kubesova, Blanka; Racil, Zdenek; Schuppert, Andreas; Costa, Ivan; Koschmieder, Steffen; Brümmendorf, Tim H.; Gezer, Deniz

Early and late stage MPN patients show distinct gene expression profiles in CD34+ cells

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Springer Science and Business Media LLC, 2021

Published in: Annals of Hematology
Baumeister, Julian; Chatain, Nicolas; Hubrich, Annika; Maié, Tiago; Costa, Ivan G.; Denecke, Bernd; Han, Lijuan; Küstermann, Caroline; Sontag, Stephanie; Seré, Kristin; Strathmann, Klaus; Zenke, Martin; Schuppert, Andreas; Brümmendorf, Tim H.; Kranc, Kamil R.; Koschmieder, Steffen; Gezer, Deniz

Hypoxia-inducible factor 1 (HIF-1) is a new therapeutic target in JAK2V617F-positive myeloproliferative neoplasms

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Springer Science and Business Media LLC, 2020

Published in: Leukemia
Harrison, Claire N.; Koschmieder, Steffen; Foltz, Lynda; Guglielmelli, Paola; Flindt, Tina; Koehler, Michael; Mathias, Jonathan; Komatsu, Norio; Boothroyd, Robert N.; Spierer, Amber; Perez Ronco, Julian; Taylor-Stokes, Gavin; Waller, John; Mesa, Ruben A.

The impact of myeloproliferative neoplasms (MPNs) on patient quality of life and productivity: results from the international MPN Landmark survey

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Springer Science and Business Media LLC, 2017

Published in: Annals of Hematology
Harrison, Claire N.; Koschmieder, Steffen; Foltz, Lynda; Guglielmelli, Paola; Flindt, Tina; Koehler, Michael; Mathias, Jonathan; Komatsu, Norio; Boothroyd, Robert N.; Spierer, Amber; Ronco, Julian Perez; Taylor-Stokes, Gavin; Waller, John; Mesa, Ruben A.

The Impact of Myeloproliferative Neoplasms (MPNs) on Patients' Quality of Life and Productivity: Results from the International MPN Landmark Survey

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American Society of Hematology, 2016

Published in: Blood
Ibarra, Juan; Elbanna, Yassmin; Kurylowicz, Katarzyna; Greenbaum, Harrison S; Evers, Maria; Arellano, Nicole S; Yang, Dongbo; Bock-Hughes, Althea; Liu, Chenyu; Smith, Quinn; Lutze, Julian; Baumeister, Julian; Kalmer, Milena; Olschok, Kathrin; Nicholson, Benjamin; Silva, Diane; Maxwell, Luke; Dowgielewicz, Jonathan; Ciboddo, Michele; Rumi, Elisa; Pietra, Daniela; Koschmieder, Steffen; Gurbuxani, Sandeep; Schneider, Rebekka K.; [...]

Type 1 Calreticulin Mutations Differentially Activate the IRE1α-XBP1 Pathway of the Unfolded Protein Response to Drive Myeloproliferative Neoplasms

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American Society of Hematology, 2021

Published in: Blood
Ibarra, Juan; Elbanna, Yassmin; Kurylowicz, Katarzyna; Ciboddo, Michele; Greenbaum, Harrison S.; Arellano, Nicole S.; Rodriguez, Deborah; Evers, Maria; Yang, Dongbo; Bock-Hughes, Althea; Liu, Chenyu; Smith, Quinn; Baumeister, Julian; Kalmer, Milena; Olschok, Kathrin; Nicholson, Benjamin; Silva, Diane; Dowgielewicz3, Jonathan; Rumi, Elisa; Pietra, Daniela; Casetti, Ilaria Carola; Koschmieder5, Steffen; Gurbuxani, Sandeep; Schneider, Rebekka K.; [...]

Abstract LB134: Type 1 calreticulin mutations differentially activate the IRE1α-XBP1 pathway of the unfolded protein response to drive myeloproliferative neoplasms

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American Association for Cancer Research (AACR), 2022

Published in: Cancer Research
Rao, Tata Nageswara; Hansen, Nils; Stetka, Jan; Luque Paz, Damien; Kalmer, Milena; Hilfiker, Julian; Endele, Max; Ahmed, Nouraiz; Kubovcakova, Lucia; Rybarikova, Margareta; Hao-Shen, Hui; Geier, Florian; Beisel, Christian; Dirnhofer, Stefan; Schroeder, Timm; Brümmendorf, Tim H.; Wolf, Dominik; Koschmieder, Steffen; Skoda, Radek C.

JAK2-V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionality

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American Society of Hematology, 2021

Published in: Blood
Olschok, Kathrin; Han, Lijuan; de Toledo, Marcelo A.S.; Böhnke, Janik; Graßhoff, Martin; Costa, Ivan G.; Theocharides, Alexandre; Maurer, Angela; Schüler, Herdit M.; Buhl, Eva Miriam; Pannen, Kristina; Baumeister, Julian; Kalmer, Milena; Gupta, Siddharth; Boor, Peter; Gezer, Deniz; Brümmendorf, Tim H.; Zenke, Martin; Chatain, Nicolas; Koschmieder, Steffen

CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes

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Elsevier BV, 2021

Published in: Stem Cell Reports
Tillmann, Stefan; Olschok, Kathrin; Schröder, Sarah K.; Bütow, Marlena; Baumeister, Julian; Kalmer, Milena; Preußger, Vera; Weinbergerova, Barbora; Kricheldorf, Kim; Mayer, Jiri; Kubesova, Blanka; Racil, Zdenek; Wessiepe, Martina; Eschweiler, Jörg; Isfort, Susanne; Brümmendorf, Tim H.; Becker, Walter; Schemionek, Mirle; Weiskirchen, Ralf; Koschmieder, Steffen; Chatain, Nicolas

The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR–ABL- and JAK2V617F-Positive MPN

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MDPI AG, 2021

Published in: Cancers

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