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Hewamana, Saman; Rowntree, Clare; Lin, Thet Thet; Pepper, Chris; Brennan, Paul; Fegan, Chris

Constitutive Nuclear p65 NF-kB Expression Predicts for Spontaneous Apoptosis and In Vitro Sensitivity to Fludarabine in CLL Cells

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American Society of Hematology, 2006

Published in: Blood
Pepper, Chris; Ward, Rachel; Starczynski, Jane; Rowntree, Clare; Pratt, Guy; Mills, Ken; Fegan, Chris

Micro-Array and Protein Analyses Reveal a Preferential Autocrine VEGF Survival Loop in CD38+ Sub-Clones When Compared with CD38− Sub-Clones Derived from the Same CLL Patient

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American Society of Hematology, 2005

Published in: Blood
Pepper, Chris; Alghazal, Suhair; Brennan, Paul; Rowntree, Clare; Pratt, Guy; Fegan, Chris

ZAP-70 Expression Is More Predictive Than VH Gene Mutational Status of BCR-Mediated Tyrosine Phosphorylation, NF-κB Activation and CLL Cell Survival

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American Society of Hematology, 2005

Published in: Blood
Al-Shaer, Laila M.; Gilkes, Amanda F.; Mills, Kenneth I.; Burnett, Alan K.; Rowntree, Clare J.

Heat Shock Protein 90 (Hsp90) Inhibition Results in Apoptotic Killing of Primary AML Cells with FLT3/ITD Mutation

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American Society of Hematology, 2004

Published in: Blood
PANAYIOTIDIS, PANOS; GANESHAGURU, K.; ROWNTREE, CLARE; JABBAR, SHIREEN A. B.; HOFFBRAND, VICTOR A.; FORONI, LETIZIA

Lack of clonal BCRA2 gene deletion on chromosome 13in chronic lymphocytic leukaemia

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Wiley, 1997

Published in: British Journal of Haematology
Furness, Caroline L.; Kirkwood, Amy; Rowntree, Clare; Vora, Ajay; Mitchell, Chris; Samarasinghe, Sujith; Goulden, Nicholas; Moorman, Anthony; Hough, Rachael

Early morphological response is significantly associated with, but does not accurately predict, relapse in teenagers and young adults aged 10–24 years with acute lymphoblastic leukaemia (ALL): results from UKALL2003

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Wiley, 2019

Published in: British Journal of Haematology
Stevenson, Matt; Pandor, Abdullah; Hamilton, Jean; Stevens, John; Rowntree, Clare; Martyn-St James, Marrissa; Rawdin, Andrew; Wong, Ruth

Ponatinib for Treating Acute Lymphoblastic Leukaemia: An Evidence Review Group Perspective of a NICE Single Technology Appraisal

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Springer Science and Business Media LLC, 2018

Published in: PharmacoEconomics
Sellar, Rob S.; Rowntree, Clare; Vora, Ajay J.; Furness, Caroline L.; Goulden, Nicholas; Mitchell, Chris; Moorman, Anthony V.; Hough, Rachael

Relapse in teenage and young adult patients treated on a paediatric minimal residual disease stratified ALL treatment protocol is associated with a poor outcome: results from UKALL2003

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Wiley, 2018

Published in: British Journal of Haematology
Sellar, Rob S; Rowntree, Clare; Vora, Ajay J.; Furness, Caroline L; Goulden, Nicholas; Mitchell, Chris; Moorman, Anthony V.; Hough, Rachael

Relapse in Teenage and Young Adult (TYA) Patients Treated on a Pediatric Minimal Residual Disease (MRD) Stratified Protocol Is Associated with a Poor Outcome: Results from UKALL2003

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American Society of Hematology, 2015

Published in: Blood
Furness, Caroline L; Rowntree, Clare; Vora, Ajay J.; Kirkwood, Amy A; Mitchell, Christopher; Goulden, Nicholas; Moorman, Anthony V.; Hough, Rachael

Use of Morphological Early Response Data to Predict Relapse in Teenage and Young Adult (TYA) Patients with Acute Lymphoblastic Leukaemia (ALL)

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American Society of Hematology, 2015

Published in: Blood
Patrick, Katharine; Wade, Rachel; Goulden, Nicholas; Mitchell, Chris; Rowntree, Clare; Hancock, Jeremy; Hough, Rachael E; Vora, Ajay J.

Improved Outcome for Children and Young People with T-Acute Lymphoblastic Leukaemia: Results of the UKALL 2003 Trial

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American Society of Hematology, 2014

Published in: Blood
Patrick, Katharine; Wade, Rachel; Goulden, Nick; Mitchell, Chris; Moorman, Anthony V.; Rowntree, Clare; Jenkinson, Sarah; Hough, Rachael; Vora, Ajay

Outcome for children and young people with Early T‐cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003

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Wiley, 2014

Published in: British Journal of Haematology
Patrick, Katharine; Wade, Rachel; Goulden, Nicholas; Rowntree, Clare; Hough, Rachael; Moorman, Anthony V; Mitchell, Christopher D; Vora, Ajay

Outcome of Down syndrome associated acute lymphoblastic leukaemia treated on a contemporary protocol

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Wiley, 2014

Published in: British Journal of Haematology
Hewamana, Saman; Lin, Thet Thet; Rowntree, Clare; Karunanithi, Kamaraj; Pratt, Guy; Hills, Robert; Fegan, Chris; Brennan, Paul; Pepper, Chris

Rel A Is an Independent Biomarker of Clinical Outcome in Chronic Lymphocytic Leukemia

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American Society of Clinical Oncology (ASCO), 2009

Published in: Journal of Clinical Oncology
Al Shaer, Laila; Walsby, Elisabeth; Gilkes, Amanda; Tonks, Amanda; Walsh, Valerie; Mills, Ken; Burnett, Alan; Rowntree, Clare

Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling

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Wiley, 2008

Published in: British Journal of Haematology
Hewamana, Saman; Lin, Thet Thet; Fegan, Chris; Knapper, Steven; Burnett, Alan; Brennan, Paul; Rowntree, Clare; Pepper, Chris

Pharmacological Inhibition of NF-KB Underpins the Strong Synergy Between LC-1 and Fludarabine in Chronic Lymphocytic Leukaemia Cells

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American Society of Hematology, 2008

Published in: Blood
Hewamana, Saman; Lin, Thet Thet; Rowntree, Clare; Karunanithi, Kamaraj; Burnett, Alan; Brennan, Paul; Fegan, Chris; Pepper, Chris

Rel a Is a Novel Prognostic Marker in CLL That Is Independent of VH Gene Mutation Status, CD38 Expression and ZAP-70 Expression

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American Society of Hematology, 2008

Published in: Blood
Hewamana, Saman; Clement, Mathew; Lin, Thet Thet; Jenkins, Chris; Fegan, Chris; Rowntree, Clare; Brennan, Paul; Pepper, Chris

Transcription Factor NF-kB as a Biomarker for Disease Progression and Target for Treatment in Chronic Lymphocytic Leukaemia

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American Society of Hematology, 2007

Published in: Blood
Kirkwood, Amy A.; Goulden, Nicholas; Moppett, John; Samarasinghe, Sujith; Mee, Jon; Hough, Rachael; Kearns, Pamela R.; Lawson, Sarah; Rowntree, Clare J.; Vora, Ajay

High Dose Methotrexate Does Not Reduce the Risk of CNS Relapse in Children and Young Adults with Acute Lymphoblastic Leukaemia and Lymphoblastic Lymphoma. Results of the Randomised Phase III Study UKALL 2011

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American Society of Hematology, 2022

Published in: Blood
Ghorashian, Sara; Samarasinghe, Sujith; Kirkwood, Amy A; Hough, Rachael; Rowntree, Clare; Lawson, Sarah; Goulden, Nicholas John; Pond, Emma; Kearns, Pamela R.; Moorman, Anthony V.; Moppett, John; Vora, Ajay

Preliminary Outcomes of Children and Young Adults with Acute Lymphoblastic Leukaemia and Down Syndrome (DS-ALL) on UKALL 2011. Reduction in Treatment-Related Mortality with De-Escalated Therapy

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American Society of Hematology, 2018

Published in: Blood

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