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Cardama GA; Gonzalez N; Ciarlantini M; Gandolfi Donadío L; Comin MJ; Alonso DF; Menna PL; Gomez DE

Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells

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2014

Published in: OncoTargets and Therapy
Gomez, Daniel; Cardama, Georgina; Gonzalez, Nazareno; Ciarlantini, Matias; Comin, Maria Julieta; Alonso, Daniel; Lorenzano Menna, Pablo; Gandolfi Donadio, Lucia

Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells

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Informa UK Limited, 2014

Published in: OncoTargets and Therapy
Hou, Hailong; Chávez, Andrés E.; Wang, Chih-Chieh; Yang, Hongtian; Gu, Hua; Siddoway, Benjamin A.; Hall, Benjamin J.; Castillo, Pablo E.; Xia, Houhui

The Rac1 Inhibitor NSC23766 Suppresses CREB Signaling by Targeting NMDA Receptor Function

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Society for Neuroscience, 2014

Published in: The Journal of Neuroscience
Adam, Oliver; Laufs, Ulrich

Rac1-Mediated Effects of HMG-CoA Reductase Inhibitors (Statins) in Cardiovascular Disease

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Mary Ann Liebert Inc, 2014

Published in: Antioxidants & Redox Signaling
Cardama, Georgina A.; Gonzalez, Nazareno; Comin, Maria Julieta; Turjanski, Adrian G.; Alonso, Daniel Fernando; Gomez, Daniel Eduardo; Menna, Pablo Lorenzano

Abstract LB-305: Novel Rac1-GEF inhibitors as anticancer agents for aggressive tumors

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American Association for Cancer Research (AACR), 2013

Published in: Cancer Research
NSC23766, an Inhibitor of Rac1, Also Acts as a Muscarinic Antagonist

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American Society for Pharmacology & Experimental Therapeutics (ASPET), 2013

Published in: Journal of Pharmacology and Experimental Therapeutics
Ferri, Nicola; Contini, Alessandro; Bernini, Sergio Kevin; Corsini, Alberto

Role of Small GTPase Protein Rac1 in Cardiovascular Diseases : Development of New Selective Pharmacological Inhibitors : Development of New Selective Pharmacological Inhibitors

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Ovid Technologies (Wolters Kluwer Health), 2013

Published in: Journal of Cardiovascular Pharmacology
Bouquier, Nathalie; Vignal, Emmanuel; Charrasse, Sophie; Weill, Mylene; Schmidt, Susanne; Léonetti, Jean-Paul; Blangy, Anne; Fort, Philippe

A Cell Active Chemical GEF Inhibitor Selectively Targets the Trio/RhoG/Rac1 Signaling Pathway

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Elsevier BV, 2009

Published in: Chemistry & Biology
Ferri, Nicola; Corsini, Alberto; Bottino, Paolo; Clerici, Francesca; Contini, Alessandro

Virtual Screening Approach for the Identification of New Rac1 Inhibitors

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American Chemical Society (ACS), 2009

Published in: Journal of Medicinal Chemistry
Ota, Takahide; Maeda, Masayo; Murakami, Manabu; Takegami, Tsutomu; Suto, Shiho; Tatsuka, Masaaki

Activation of Rac1 by Rho‐guanine nucleotide dissociation inhibitor‐β with defective isoprenyl‐binding pocket

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Wiley, 2007

Published in: Cell Biology International
Lambeng, Nathalie; Coutadeur, Séverine; Peillon, Hélène; Loiseau, Nadia; Bachelot, Florence; De Oliveira, Catherine; Carton, Rachel; Leblond, Bertr; Beausoleil, Eric; Chauvignac, Cédric; Taverne, Thierry; Schweighoffer, Fabien; Desire, Laurent

P2‐339: Development of a screening platform for the identification of new Rac1/Rac1b inhibitors active in the prevention of amyloid‐beta production

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Wiley, 2008

Published in: Alzheimer's & Dementia
Dipankar, Pankaj; Kumar, Puneet; Sarangi, Pranita P.

In silico identification and characterization of small-molecule inhibitors specific to RhoG/Rac1 signaling pathway

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Informa UK Limited, 2023

Published in: Journal of Biomolecular Structure and Dynamics
Ahmed, Salsabil; Mazumder, Suman; Wiesen, Lisa; Sharma, Neeraj; Mukherjee, Ujjal Kumar; Kumar, Shaji K; Baughn, Linda B.; Van Ness, Brian G.; Mitra, Amit Kumar

Validation of a Novel Rac1 Inhibitor As Potent Secdrug Against Activating Ras Mutant and Drug-Resistant Multiple Myeloma

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American Society of Hematology, 2022

Published in: Blood
Zheng, Chunwen; Wu, Xiaodong; Zeng, Ruijie; Lin, Lirui; Xu, Liyan; Li, Enmin; Dong, Geng

Computational Prediction of Hot Spots and Binding Site of Inhibitor NSC23766 on Rac1 Binding With Tiam1

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Frontiers Media SA, 2021

Published in: Frontiers in Chemistry
Ciarlantini, Matías S.; Barquero, Andrea; Bayo, Juan; Wetzler, Diana; Dodes Traian, Martín M.; Bucci, Hernán A.; Fiore, Esteban J.; Gandolfi Donadío, Lucía; Defelipe, Lucas; Turjanski, Adrián; Ramírez, Javier A.; Mazzolini, Guillermo; Comin, Maria J.

Development of an Improved Guanidine‐Based Rac1 Inhibitor with in vivo Activity against Non‐Small Cell Lung Cancer

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Wiley, 2021

Published in: ChemMedChem
Pham, Thao; Decant, Brian T.; Kumar, Krishan; Shang, Meng; Matsangou, Maria; Ebine, Kazumi; Munshi, Hidayatullah G.

Abstract 2989: BET inhibitors induce Rac1-dependent MNK and eIF4E phosphorylation in cancer cells

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American Association for Cancer Research (AACR), 2018

Published in: Cancer Research
Mohan, A.; Dean, K.; Han, S.; Welf, E.; Danuser, G.

LB993 Focal adhesions mediate Rac1P29S-dependent drug resistance to MAPK inhibitors in melanoma

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Elsevier BV, 2017

Published in: Journal of Investigative Dermatology
Xiao-yong HAN; Xi-rui WANG; Zhi-huang ZHAO; Jin-xing SHANG; Gang-feng YIN; Xue-jun YANG

Study on synergistic effect of Rac1 inhibitor and temozolomide in inhibiting proliferation and invasiveness of glioma cells in vitro

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2016

Published in: Chinese Journal of Contemporary Neurology and Neurosurgery
Dütting, S.; Heidenreich, J.; Cherpokova, D.; Amin, E.; Zhang, S.‐C.; Ahmadian, M.R.; Brakebusch, C.; Nieswandt, B.

Critical off‐target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets

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Elsevier BV, 2015

Published in: Journal of Thrombosis and Haemostasis
Dierkes, Rüdiger; Warnking, Kathrin; Liedmann, Swantje; Seyer, Roman; Ludwig, Stephan; Ehrhardt, Christina

The Rac1 Inhibitor NSC23766 Exerts Anti-Influenza Virus Properties by Affecting the Viral Polymerase Complex Activity

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Public Library of Science (PLoS), 2014

Published in: PLoS ONE

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