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Yoda, Akinori; Adelmant, Guillaume; Tamburini, Jerome; Chapuy, Bjoern; Shindoh, Nobuaki; Yoda, Yuka; Weigert, Oliver; Kopp, Nadja; Wu, Shuo-Chieh; Kim, Sunhee S; Liu, Huiyun; Tivey, Trevor; Christie, Amanda L; Elpek, Kutlu G; Card, Joseph; Gritsman, Kira; Gotlib, Jason; Deininger, Michael W; Makishima, Hideki; Turley, Shannon J; Javidi-Sharifi, Nathalie; Maciejewski, Jaroslaw P; Jaiswal, Siddhartha; Ebert, Benjamin L; [...]Mutations in G protein β subunits promote transformation and kinase inhibitor resistanceView onlineSchließen
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Published in: Nature Medicine
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Yoda, Akinori; Adelmant, Guillaume; Tamburini, Jerome; Chapuy, Bjoern; Shindoh, Nobuaki; Yoda, Yuka; Weigert, Oliver; Kopp, Nadja; Wu, Shuo-Chieh; Kim, Sunhee S.; Liu, Huiyun; Tivey, Trevor; Christie, Amanda L; Elpek, Kutlu G; Card, Joseph; Gritsman, Kira; Gotlib, Jason; Deininger, Michael W.; Makishima, Hideki; Turley, Shannon; Javidi-Sharifi, Nathalie; Maciejewski, Jaroslaw P.; Rodig, Scott J; Tyner, Jeffrey W.; [...]GNB1 Activating Mutations Promote Myeloid and Lymphoid Neoplasms Targetable By Combined PI3K/mTOR InhibitionView onlineSchließen
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Published in: Blood
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Lozupone, Catherine; Cota-Gomez, Adela; Palmer, Brent E.; Linderman, Derek J.; Charlson, Emily S.; Sodergren, Erica; Mitreva, Makedonka; Abubucker, Sahar; Martin, John; Yao, Guohui; Campbell, Thomas B.; Flores, Sonia C.; Ackerman, Gail; Stombaugh, Jesse; Ursell, Luke; Beck, James M.; Curtis, Jeffrey L.; Young, Vincent B.; Lynch, Susan V.; Huang, Laurence; Weinstock, George M.; Knox, Kenneth S.; Twigg, Homer; Morris, Alison; [...]Widespread Colonization of the Lung by Tropheryma whipplei in HIV InfectionView onlineSchließen
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Published in: American Journal of Respiratory and Critical Care Medicine
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Leslie, Elizabeth J.; Taub, Margaret A.; Liu, Huan; Steinberg, Karyn Meltz; Koboldt, Daniel C.; Zhang, Qunyuan; Carlson, Jenna C.; Hetmanski, Jacqueline B.; Wang, Hang; Larson, David E.; Fulton, Robert S.; Kousa, Youssef A.; Fakhouri, Walid D.; Naji, Ali; Ruczinski, Ingo; Begum, Ferdouse; Parker, Margaret M.; Busch, Tamara; Standley, Jennifer; Rigdon, Jennifer; Hecht, Jacqueline T.; Scott, Alan F.; Wehby, George L.; Christensen, Kaare; [...]Identification of Functional Variants for Cleft Lip with or without Cleft Palate in or near PAX7, FGFR2, and NOG by Targeted Sequencing of GWAS LociView onlineSchließen
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Published in: The American Journal of Human Genetics
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Assatova, Bimarzhan; Willim, Robert; Trevisani, Christopher; Haskett, Garrett; Kariya, Khyati Maulik; Chopra, Kusha; Park, Sung Rye; Tolstorukov, Michael Yevgeniy; McCabe, Sean M.; Duffy, Jessica; Louissaint, Abner; Huuhtanen, Jani; Bhattacharya, Dipabarna; Mustjoki, Satu; Koh, Min Jung; Powers, Foster; Morgan, Elizabeth A.; Yang, Lei; Pinckney, Brandy; Cotton, Matthew J.; Crabbe, Andrew; Ziemba, Jessica Beth; Brain, Ian; Heavican-Foral, Tayla B.; [...]KLRG1 Cell Depletion as a Novel Therapeutic Strategy in Patients with Mature T-Cell Lymphoma SubtypesView onlineSchließen
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Published in: Clinical Cancer Research
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Bouska, Alyssa; Zhang, Weiwei; Sharma, Sunandini; Holte, Harald; Shah, Ab Rauf; Lone, Waseem Gul; Cappelli, Luca Vincenzo; Fiore, Danilo; Gong, Qiang; Heavican-Foral, Tayla; Cannatella, Jeffrey; Amador, Catalina; Arif, Aiza; Smith, Lynette; Lim, Soon Thye; Ong, Choon Kiat; Feldman, Andrew L.; Du, Ming-Qing; de Leval, Laurence; Greiner, Timothy C.; Fu, Kai; Trøen, Gunhild; Vodak, Daniel; Nakken, Sigve; [...]Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T-Cell LymphomaView onlineSchließen
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Published in: Blood
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Marrie, Ruth Ann; Miller, Aaron; Sormani, Maria Pia; Thompson, Alan; Waubant, Emmanuelle; Trojano, Maria; O'Connor, Paul; Reingold, Stephen; Cohen, Jeffrey A.; Banwell, Brenda; Bebo, Bruce; Bernstein, Charles; Comi, Giancarlo; Conway, Devon; Cutter, Gary; Derfuss, Tobias; Fiest, Kirsten; Finlayson, Marcia; Giovannoni, Gavin; Goodman, Andrew; Green, Ari; Hemmer, Bernhard; Horwitz, Ralph; Jette, Nathalie; [...]The challenge of comorbidity in clinical trials for multiple sclerosisView onlineSchließen
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Published in: Neurology
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Marrie, Ruth Ann; Miller, Aaron; Sormani, Maria Pia; Thompson, Alan; Waubant, Emmanuelle; Trojano, Maria; O'Connor, Paul; Fiest, Kirsten; Reider, Nadia; Reingold, Stephen; Cohen, Jeffrey A.; Banwell, Brenda; Bebo, Bruce; Bernstein, Charles; Comi, Giancarlo; Conway, Devon; Cutter, Gary; Derfuss, Tobias; Finlayson, Marcia; Giovannoni, Gavin; Goodman, Andrew; Green, Ari; Hemmer, Bernhard; Horwitz, Ralph; [...]Recommendations for observational studies of comorbidity in multiple sclerosisView onlineSchließen
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Published in: Neurology
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Libman, Ingrid; Bingley, Polly J.; Becker, Dorothy; Buckner, Jane H.; DiMeglio, Linda A.; Gitelman, Stephen E.; Greenbaum, Carla; Haller, Michael J.; Ismail, Heba M.; Krischer, Jeffrey; Moore, Wayne V.; Moran, Antoinette; Muir, Andrew B.; Raman, Vana; Steck, Andrea K.; Toledo, Frederico G.S.; Wentworth, John; Wherrett, Diane; White, Perrin; You, Lu; Herold, Kevan C.; Steck, Andrea K.; Greenbaum, Carla; Lord, Sandra; [...]Hydroxychloroquine in Stage 1 Type 1 DiabetesView onlineSchließen
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Published in: Diabetes Care
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Goodman, Andrew D; Bethoux, Francois; Brown, Theodore R; Schapiro, Randall T; Cohen, Ron; Marinucci, Lawrence N; Henney, Herbert R; Blight, Andrew R; Agius, M; Arnason, BGW; Bethoux, FA; Bever, CT; Bowen, JD; Brown, TR; Dietrich, DW; Edwards, K; Freedman, MS; Freedman, M; Kachuck, NJ; Kaufman, MD; Keilson, M; Khan, O; Krupp, LB; Leist, TP; [...]Long-term safety and efficacy of dalfampridine for walking impairment in patients with multiple sclerosis: Results of open-label extensions of two Phase 3 clinical trialsView onlineSchließen
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Published in: Multiple Sclerosis Journal
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Fox, Robert J.; Coffey, Christopher S.; Conwit, Robin; Cudkowicz, Merit E.; Gleason, Trevis; Goodman, Andrew; Klawiter, Eric C.; Matsuda, Kazuko; McGovern, Michelle; Naismith, Robert T.; Ashokkumar, Akshata; Barnes, Janel; Ecklund, Dixie; Klingner, Elizabeth; Koepp, Maxine; Long, Jeffrey D.; Natarajan, Sneha; Thornell, Brenda; Yankey, Jon; Bermel, Robert A.; Debbins, Josef P.; Huang, Xuemei; Jagodnik, Patricia; Lowe, Mark J.; [...]Phase 2 Trial of Ibudilast in Progressive Multiple SclerosisView onlineSchließen
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Published in: New England Journal of Medicine
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Gibbs, Richard A.; Weinstock, George M.; Metzker, Michael L.; Muzny, Donna M.; Sodergren, Erica J.; Scherer, Steven; Scott, Graham; Steffen, David; Worley, Kim C.; Burch, Paula E.; Okwuonu, Geoffrey; Hines, Sandra; Lewis, Lora; DeRamo, Christine; Delgado, Oliver; Dugan-Rocha, Shannon; Miner, George; Morgan, Margaret; Hawes, Alicia; Gill, Rachel; Holt, Celera Robert A.; Adams, Mark D.; Amanatides, Peter G.; Baden-Tillson, Holly; [...]Genome sequence of the Brown Norway rat yields insights into mammalian evolutionView onlineSchließen
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Published in: Nature
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Yilmaz, Pelin; Kottmann, Renzo; Field, Dawn; Knight, Rob; Cole, James R; Amaral-Zettler, Linda; Gilbert, Jack A; Karsch-Mizrachi, Ilene; Johnston, Anjanette; Cochrane, Guy; Vaughan, Robert; Hunter, Christopher; Park, Joonhong; Morrison, Norman; Rocca-Serra, Philippe; Sterk, Peter; Arumugam, Manimozhiyan; Bailey, Mark; Baumgartner, Laura; Birren, Bruce W; Blaser, Martin J; Bonazzi, Vivien; Booth, Tim; Bork, Peer; [...]Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specificationsView onlineSchließen
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Published in: Nature Biotechnology
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Weinstock, Joshua S.; Laurie, Cecelia A.; Broome, Jai G.; Taylor, Kent D.; Guo, Xiuqing; Shuldiner, Alan R.; O’Connell, Jeffrey R.; Lewis, Joshua P.; Boerwinkle, Eric; Barnes, Kathleen C.; Chami, Nathalie; Kenny, Eimear E.; Loos, Ruth J. F.; Fornage, Myriam; Redline, Susan; Cade, Brian E.; Gilliland, Frank D.; Chen, Zhanghua; Gauderman, W. James; Kumar, Rajesh; Grammer, Leslie; Schleimer, Robert P.; Psaty, Bruce M.; Bis, Joshua C.; [...]The genetic determinants of recurrent somatic mutations in 43,693 blood genomesView onlineSchließen
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Published in: Science Advances
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Lander, Eric S.; Linton, Lauren M.; Birren, Bruce; Nusbaum, Chad; Zody, Michael C.; Baldwin, Jennifer; Devon, Keri; Dewar, Ken; Doyle, Michael; FitzHugh, William; Funke, Roel; Gage, Diane; Harris, Katrina; Heaford, Andrew; Howland, John; Kann, Lisa; Lehoczky, Jessica; LeVine, Rosie; McEwan, Paul; McKernan, Kevin; Meldrim, James; Mesirov, Jill P.; Miranda, Cher; Morris, William; [...]Initial sequencing and analysis of the human genomeView onlineSchließen
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Published in: Nature
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Gibbs, Richard A.; Rogers, Jeffrey; Katze, Michael G.; Bumgarner, Roger; Weinstock, George M.; Mardis, Elaine R.; Remington, Karin A.; Strausberg, Robert L.; Venter, J. Craig; Wilson, Richard K.; Batzer, Mark A.; Bustamante, Carlos D.; Eichler, Evan E.; Hahn, Matthew W.; Hardison, Ross C.; Makova, Kateryna D.; Miller, Webb; Milosavljevic, Aleksandar; Palermo, Robert E.; Siepel, Adam; Sikela, James M.; Attaway, Tony; Bell, Stephanie; Bernard, Kelly E.; [...]Evolutionary and Biomedical Insights from the Rhesus Macaque GenomeView onlineSchließen
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Published in: Science
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Shinnar, Shlomo; Cnaan, Avital; Hu, Fengming; Clark, Peggy; Dlugos, Dennis; Hirtz, Deborah G.; Masur, David; Mizrahi, Eli M.; Moshé, Solomon L.; Glauser, Tracy A.; Abram, Harry; Albers, Ellen; Bahna, Samar J.; Ballaban-Gil, Karen; Barrera, Jose; Belaineh, Tekolla; Bertrand, Mary; Blumenfeld, Hal; Borror, Sarah; Borzy, Charlie; Brantz, Susan; Cardoza, Candace; Chapman, Kevin; Chugani, Harry T.; [...]Long-term outcomes of generalized tonic-clonic seizures in a childhood absence epilepsy trialView onlineSchließen
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Published in: Neurology
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Lozano, Rafael; Naghavi, Mohsen; Foreman, Kyle; Lim, Stephen; Shibuya, Kenji; Aboyans, Victor; Abraham, Jerry; Adair, Timothy; Aggarwal, Rakesh; Ahn, Stephanie Y; AlMazroa, Mohammad A; Alvarado, Miriam; Anderson, H Ross; Anderson, Laurie M; Andrews, Kathryn G; Atkinson, Charles; Baddour, Larry M; Barker-Collo, Suzanne; Bartels, David H; Bell, Michelle L; Benjamin, Emelia J; Bennett, Derrick; Bhalla, Kavi; Bikbov, Boris; [...]Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010View onlineSchließen
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Published in: The Lancet
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Gravel, Simon; Henn, Brenna M.; Gutenkunst, Ryan N.; Indap, Amit R.; Marth, Gabor T.; Clark, Andrew G.; Yu, Fuli; Gibbs, Richard A.; Bustamante, Carlos D.; Altshuler, David L.; Durbin, Richard M.; Abecasis, Gonçalo R.; Bentley, David R.; Chakravarti, Aravinda; Clark, Andrew G.; Collins, Francis S.; De La Vega, Francisco M.; Donnelly, Peter; Egholm, Michael; Flicek, Paul; Gabriel, Stacey B.; Gibbs, Richard A.; Knoppers, Bartha M.; Lander, Eric S.; [...]Demographic history and rare allele sharing among human populationsView onlineSchließen
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Published in: Proceedings of the National Academy of Sciences
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Weinstock, Joshua S.; Gopakumar, Jayakrishnan; Burugula, Bala Bharathi; Uddin, Md Mesbah; Jahn, Nikolaus; Belk, Julia A.; Bouzid, Hind; Daniel, Bence; Miao, Zhuang; Ly, Nghi; Mack, Taralynn M.; Luna, Sofia E.; Prothro, Katherine P.; Mitchell, Shaneice R.; Laurie, Cecelia A.; Broome, Jai G.; Taylor, Kent D.; Guo, Xiuqing; Sinner, Moritz F.; von Falkenhausen, Aenne S.; Kääb, Stefan; Shuldiner, Alan R.; O’Connell, Jeffrey R.; Lewis, Joshua P.; [...]Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesisView onlineSchließen
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Published in: Nature