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Ramm, Susanne [Author] ; Mally, Angela [Degree supervisor]

Mechanismen idiosynkratischer Lebertoxizität - Einfluss von Arzneistoff-unabhängigen Stressfaktoren auf die Bildung reaktiver Metaboliten und zellulären Stress

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Würzburg: Universitätsbibliothek der Universität Würzburg, 2012
Al-Attrache, Houssein [Author]

Study of the idiosyncratic toxicity of drugs in HepaRG and yeast : influence of inflammatory stress and biotransformation ; Etude de la toxicité idiosyncratique de médicaments sur cellules HepaRG et levure : influence du stress inflammatoire et de la biotransformation

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[Erscheinungsort nicht ermittelbar]: HAL CCSD, 2016
Yamada, Hisaharu

Front-line Research of Idiosyncratic Drug Toxicity

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Pharmaceutical Society of Japan, 2015

Published in: YAKUGAKU ZASSHI, 135 (2015) 4, Seite 565-566
Tafazoli, Shahrzad; Spehar, Dane; O'Brien, Peter

Oxidative Stress Mediated Idiosyncratic Drug Toxicity

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Informa UK Limited, 2005

Published in: Drug Metabolism Reviews, 37 (2005) 2, Seite 311-325
Tafazoli, Shahrzad; Spehar, Dane D.; O'Brien, Peter J.

Oxidative Stress Mediated Idiosyncratic Drug Toxicity

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Informa UK Limited, 2005

Published in: Drug Metabolism Reviews, 37 (2005) 2, Seite 311-325
IKEDA, Toshihiko

Idiosyncratic Drug Toxicity-View from Pharmacokinetics and Drug Metabolism-

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The Mass Spectrometry Society of Japan, 2005

Published in: Journal of the Mass Spectrometry Society of Japan, 53 (2005) 3, Seite 142-145
Susukida, Takeshi; Aoki, Shigeki; Shirayanagi, Tomohiro; Yamada, Yushiro; Kuwahara, Saki; Ito, Kousei

HLA transgenic mice: application in reproducing idiosyncratic drug toxicity

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Informa UK Limited, 2020

Published in: Drug Metabolism Reviews, 52 (2020) 4, Seite 540-567
Mosedale, Merrie; Watkins, Paul B.

Understanding Idiosyncratic Toxicity: Lessons Learned from Drug-Induced Liver Injury

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American Chemical Society (ACS), 2020

Published in: Journal of Medicinal Chemistry, 63 (2020) 12, Seite 6436-6461
Raza, Ahmad; Chan, Vincent; Atiq, Muhammad Umair

Idiosyncratic Drug Reaction: A Rare Mechanism of Acute Tylenol Toxicity

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Springer Science and Business Media LLC, 2019

Published in: Cureus (2019)
Ikeda, Toshihiko

Recent Findings Regarding the Mechanism of Idiosyncratic Drug Toxicity

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Pharmaceutical Society of Japan, 2015

Published in: YAKUGAKU ZASSHI, 135 (2015) 4, Seite 567-578
Aithal, Guruprasad P

Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity

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Informa Healthcare, 2004

Published in: Expert Opinion on Drug Safety, 3 (2004) 6, Seite 519-523
Park, B.Kevin; Kitteringham, Neil R.; Powell, Helen; Pirmohamed, Munir

Advances in molecular toxicology–towards understanding idiosyncratic drug toxicity

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Elsevier BV, 2000

Published in: Toxicology, 153 (2000) 1-3, Seite 39-60
Ulrich, Roger G; Bacon, James A; Brass, Eric P; Cramer, Clay T; Petrella, Diane K; Sun, Elena L

Metabolic, idiosyncratic toxicity of drugs: overview of the hepatic toxicity induced by the anxiolytic, panadiplon

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Elsevier BV, 2001

Published in: Chemico-Biological Interactions, 134 (2001) 3, Seite 251-270
Susukida, Takeshi; Aoki, Shigeki; Kogo, Kotaro; Fujimori, Sota; Song, Binbin; Liu, Cong; Sekine, Shuichi; Ito, Kousei

Evaluation of immune-mediated idiosyncratic drug toxicity using chimeric HLA transgenic mice

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Springer Science and Business Media LLC, 2018

Published in: Archives of Toxicology, 92 (2018) 3, Seite 1177-1188
Cruz‐Monteagudo, Maykel; Cordeiro, M. Natália D. S.; Borges, Fernanda

Computational chemistry approach for the early detection of drug‐induced idiosyncratic liver toxicity

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Wiley, 2008

Published in: Journal of Computational Chemistry, 29 (2008) 4, Seite 533-549
Boelsterli, Urs A.; Zimmerman, Hyman J.; Kretz-Rommel, Anke

Idiosyncratic Liver Toxicity of Nonsteroidal Antiinflammatory Drugs: Molecular Mechanisms and Pathology

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Informa UK Limited, 1995

Published in: Critical Reviews in Toxicology, 25 (1995) 3, Seite 207-235
Benesic, Andreas; Jalal, Kowcee; Gerbes, Alexander L

Drug-Drug Combinations Can Enhance Toxicity as Shown by Monocyte-Derived Hepatocyte-like Cells From Patients With Idiosyncratic Drug-Induced Liver Injury

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Oxford University Press (OUP), 2019

Published in: Toxicological Sciences, 171 (2019) 2, Seite 296-302
Lavergne, S. N.; Danhof, R. S.; Volkman, E. M.; Trepanier, L. A.

Association of drug‐serum protein adducts and anti‐drug antibodies in dogs with sulphonamide hypersensitivity: A naturally occurring model of idiosyncratic drug toxicity

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Wiley, 2006

Published in: Clinical & Experimental Allergy, 36 (2006) 7, Seite 907-915
Shimada, Hiroaki; Ikuta, Hiroyuki; Kumazawa, Keisuke; Nomi, Manato; Shiojiri, Mayumi; Kawase, Atsushi; Iwaki, Masahiro

Relationship between the risk of idiosyncratic drug toxicity and formation and degradation profiles of acyl-glucuronide metabolites of nonsteroidal anti-inflammatory drugs in rat liver microsomes

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Elsevier BV, 2022

Published in: European Journal of Pharmaceutical Sciences, 174 (2022), Seite 106193
Stepan, Antonia F.; Walker, Daniel P.; Bauman, Jonathan; Price, David A.; Baillie, Thomas A.; Kalgutkar, Amit S.; Aleo, Michael D.

Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States

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American Chemical Society (ACS), 2011

Published in: Chemical Research in Toxicology, 24 (2011) 9, Seite 1345-1410

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