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Vieri, Margherita; Rolles, Benjamin; Crocioni, Maria; Schemionek-Reinders, Mirle; Isfort, Susanne; Panse, Jens; Brümmendorf, Tim H.; Beier, Fabian

Eltrombopag Preserves the Clonogenic Potential of Hematopoietic Stem Cells During Treatment With Antithymocyte Globulin in Patients With Aplastic Anemia

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Wiley, 2023

Published in: HemaSphere
Isfort, Susanne; Gambacorti-Passerini, Carlo; Brümmendorf, Tim H; Smith, B. Douglas; Purcell, Simon; Zhao, Huadong; Kuttschreuter, Luke; Apperley, Jane

PB1966: THE EFFECT OF BODY MASS INDEX ON THE SAFETY OF BOSUTINIB IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA: A POST HOC POOLED DATA ANALYSIS

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Wiley, 2023

Published in: HemaSphere
Metselaar, Josbert; Lammers, Twan; Boquoi, Amelie; Fenk, Roland; Testaquadra, Fabio; Schemionek, Mirle; Kiessling, Fabian; Isfort, Susanne; Wilop, Stefan; Crysandt, Martina

A phase I first-in-man study to investigate the pharmacokinetics and safety of liposomal dexamethasone in patients with progressive multiple myeloma

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Springer Science and Business Media LLC, 2023

Published in: Drug Delivery and Translational Research
Vieri, Margherita; Kirschner, Martin; Tometten, Mareike; Abels, Anne; Rolles, Benjamin; Isfort, Susanne; Panse, Jens; Brümmendorf, Tim H.; Beier, Fabian

Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Congenita

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MDPI AG, 2020

Published in: International Journal of Molecular Sciences
Brümmendorf, Tim H.; Gambacorti-Passerini, Carlo; Bushmakin, Andrew G.; Cappelleri, Joseph C.; Viqueira, Andrea; Reisman, Arlene; Isfort, Susanne; Mamolo, Carla

Relationship between molecular response and quality of life with bosutinib or imatinib for chronic myeloid leukemia

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Springer Science and Business Media LLC, 2020

Published in: Annals of Hematology
Lubberich, Richard K.; Walenda, Thomas; Goecke, Tamme W.; Strathmann, Klaus; Isfort, Susanne; Brümmendorf, Tim H.; Koschmieder, Steffen; Wagner, Wolfgang

Serum of myeloproliferative neoplasms stimulates hematopoietic stem and progenitor cells

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Public Library of Science (PLoS), 2018

Published in: PLOS ONE
Han, Lijuan; Schubert, Claudia; Köhler, Johanna; Schemionek, Mirle; Isfort, Susanne; Brümmendorf, Tim H.; Koschmieder, Steffen; Chatain, Nicolas

Calreticulin-mutant proteins induce megakaryocytic signaling to transform hematopoietic cells and undergo accelerated degradation and Golgi-mediated secretion

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Springer Science and Business Media LLC, 2016

Published in: Journal of Hematology & Oncology
Zhang, Kailun David; Jost, Edgar; Panse, Jens; Herwartz, Reinhild; Lindemann-Docter, Katharina; Jonigk, Danny; Kricheldorf, Kim; Köchel, Anja; Sauerbrunn, Nicolas; Brümmendorf, Tim H.; Koschmieder, Steffen; Isfort, Susanne

Bone marrow biopsy in geriatric patients above the age of 85 years: invaluable or unnecessary? A retrospective analysis

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Springer Science and Business Media LLC, 2024

Published in: Annals of Hematology
Olschok, Kathrin; Altenburg, Bianca; de Toledo, Marcelo A.S.; Maurer, Angela; Abels, Anne; Beier, Fabian; Gezer, Deniz; Isfort, Susanne; Brümmendorf, Tim H; Zenke, Martin; Chatain, Nicolas; Koschmieder, Steffen

P1008: THE TELOMERASE INHIBITOR IMETELSTAT DIFFERENTIALLY TARGETS JAK2V617F- VERSUS CALR-MUTANT MYELOPROLIFERATIVE NEOPLASM CELLS AND INHIBITS JAK-STAT SIGNALING

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Wiley, 2023

Published in: HemaSphere
Walter, Jeanette; Petermann-Meyer, Andrea; Soysal, Hatice; Doleschall, Anna; Christen, Deborah; Kricheldorf, Kim; Isfort, Susanne; Brümmendorf, Tim H.; Beier, Fabian; Panse, Jens

Quality of Life Analysis in Patients with AA Using the QLQ-AA/PNH-54 at Initial Diagnosis of AA - a Registry Based Analysis

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American Society of Hematology, 2023

Published in: Blood
Walter, Jeanette; Kricheldorf, Kim; Schumacher, Yannic; Isfort, Susanne; Chromik, Jörg; Drexler, Beatrice; Theis, Frauke; Panse, Jens; Brümmendorf, Tim H.; Beier, Fabian

Real-Life Data of Cyclosporine (CsA) Tapering in Patients with Very/ Severe Aplastic Anemia (v/sAA) Treated with Horse Anti-Thymocyte Globulin (hATG/CsA) Suggest Higher Risk of AA Relapse at Cyclosporine Plasma Levels below 100 Nanogram per Milliliter

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American Society of Hematology, 2023

Published in: Blood
Kalmer, Milena; Pannen, Kristina; Lemanzyk, Rebecca; Wirths, Chiara; Baumeister, Julian; Maurer, Angela; Kricheldorf, Kim; Schifflers, Joelle; Gezer, Deniz; Isfort, Susanne; Brümmendorf, Tim H.; Koschmieder, Steffen; Chatain, Nicolas

Clonogenic assays improve determination of variant allele frequency of driver mutations in myeloproliferative neoplasms

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Springer Science and Business Media LLC, 2022

Published in: Annals of Hematology
Elbracht, Miriam; Meyer, Robert; Kricheldorf, Kim; Gezer, Deniz; Thomas, Eggermann; Betz, Beate; Kurth, Ingo; Teichmann, Lino L.; Brümmendorf, Tim H.; Germing, Ulrich; Isfort, Susanne; Koschmieder, Steffen

Germline variants in DNA repair genes, including BRCA1/2, may cause familial myeloproliferative neoplasms

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American Society of Hematology, 2021

Published in: Blood Advances
Cyra, Magdalene; Huss, Sebastian; Schulte, Miriam; Isfort, Ilka; Hafner, Susanne; Simmet, Thomas; Kindler, Thomas; Åman, Pierre; Wardelmann, Eva; Hartmann, Wolfgang; Trautmann, Marcel

Abstract 1257: The transcription factor CREB is essential in myxoid liposarcoma

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American Association for Cancer Research (AACR), 2019

Published in: Cancer Research
Kirschner, Martin; Bornemann, Anne; Schubert, Claudia; Gezer, Deniz; Kricheldorf, Kim; Isfort, Susanne; Brümmendorf, Tim H.; Schemionek, Mirle; Chatain, Nicolas; Skorski, Tomasz; Koschmieder, Steffen

Transcriptional alteration of DNA repair genes in Philadelphia chromosome negative myeloproliferative neoplasms

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Springer Science and Business Media LLC, 2019

Published in: Annals of Hematology
Kirschner, Martin M.; Schemionek, Mirle; Schubert, Claudia; Chatain, Nicolas; Sontag, Stephanie; Isfort, Susanne; Ortiz-Brüchle, Nadina; Bennemann, Karla; Zerres, Klaus; Zenke, Martin; Bruemmendorf, Tim H.; Koschmieder, Steffen

Dissecting Genomic Aberrations In CML and Bcr-Abl Negative Myeloproliferative Neoplasms By The Use Of Multiplex-PCR and Parallel Resequencing

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American Society of Hematology, 2013

Published in: Blood
Koschmieder, Steffen; Isfort, Susanne; Schulte, Clemens; Jacobasch, Lutz; Geer, Thomas; Reiser, Marcel; Koenigsmann, Michael; Heinrich, Bernhard; Wehmeyer, Jürgen; von der Heyde, Eyck; Tesch, Hans; Gröschl, Benedikt; Bachhuber, Petra; Großer, Susanne; Pahl, Heike L.

Real-world analysis of ruxolitinib in myelofibrosis: interim results focusing on patients who were naïve to JAK inhibitor therapy treated within the JAKoMo non-interventional, phase IV trial

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Springer Science and Business Media LLC, 2023

Published in: Annals of Hematology
Isfort, Susanne; Wolf, Dominik; Teichmann, Lino L.; Crysandt, Martina; Burchert, Andreas; Hochhaus, Andreas; Saussele, Susanne; Kiani, Alexander; Göthert, Joachim R; Illmer, Thomas; Schafhausen, Philippe; Warnken-Uhlich, Mareille; Wolber, Uta; Kohn, Denise; Manz, Kirsi; Pfirrmann, Markus; Brummendorf, Tim H.H.

Health-Related Quality of Life of CML Patients Under 2nd or 3rd Line Bosutinib Is Not Impaired Significantly By Gastrointestinal Toxicity (GI Tox) but Influenced By Sex - Results from a Subanalysis of the Bosutinib Dose Optimization (BODO) Study (CML-VII) Trial of the German CML Study Group

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American Society of Hematology, 2022

Published in: Blood
Isfort, Susanne; Wolf, Dominik; Teichmann, Lino L.; Crysandt, Martina; Burchert, Andreas; Hochhaus, Andreas; Saussele, Susanne; Kiani, Alexander; Göthert, Joachim R.; Illmer, Thomas; Schafhausen, Philippe; Warnken-Uhlich, Mareille; Wolber, Uta; Kohn, Denise; Manz, Kirsi; Pfirrmann, Markus; Brümmendorf, Tim H

Step-in Dosing in the Bosutinib Dose Optimization Study (BODO) Failed to Reduce Gastrointestinal (GI) Toxicity in Patients Failing Second Generation TKI (2G-TKI) in Chronic Phase Chronic Myeloid Leukemia (CML) but Suggests Promising Molecular Response

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American Society of Hematology, 2021

Published in: Blood
Walter, Jeanette; Rolles, Benjamin; Schumacher, Yannic; Theis, Frauke; Hansmann, Leo; Heudobler, Daniel; Radsak, Markus; Heuser, Michael; Georgi, Julia-Annabell; Chromik, Jörg; Drexler, Beatrice; Schubert, Jörg; Kricheldorf, Kim; Isfort, Susanne; Panse, Jens; Brümmendorf, Tim H.; Beier, Fabian

Analysis of the Impact of Body Mass Index (BMI) on the Durability of Response in Patients with Aplastic Anemia Treated with Weight-Adjusted Horse Anti-Thymocyte Globulin (hATG)

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American Society of Hematology, 2023

Published in: Blood

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