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Gernert, Manuela; Richter, Angelika; Löscher, Wolfgang

In vivo extracellular electrophysiology of pallidal neurons in dystonic and nondystonic hamsters

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Wiley, 1999

Published in: Journal of Neuroscience Research, 57 (1999) 6, Seite 894-905
Gernert, Manuela; Richter, Angelika; L�scher, Wolfgang

Subconvulsive dose of pentylenetetrazole increases the firing rate of substantia nigra pars reticulata neurons in dystonic but not in nondystonic hamsters

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Wiley, 1999

Published in: Synapse, 33 (1999) 4, Seite 259-267
Gernert, Manuela; Richter, Angelika; Löscher, Wolfgang

The electrical activity is impaired in the red nucleus of dtsz mutant hamsters with paroxysmal dystonia: an EEG power spectrum analysis of depth electrode recordings

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Elsevier BV, 1997

Published in: Brain Research, 760 (1997) 1-2, Seite 102-108
Richter, Angelika; Gernert, Manuela; Löscher, Wolfgang

Prodystonic effects of riluzole in an animal model of idiopathic dystonia related to decreased total power in the red nucleus?

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Elsevier BV, 1997

Published in: European Journal of Pharmacology, 332 (1997) 2, Seite 133-141
Töllner, Kathrin; Wolf, Saskia; Löscher, Wolfgang; Gernert, Manuela

The Anticonvulsant Response to Valproate in Kindled Rats Is Correlated with Its Effect on Neuronal Firing in the Substantia Nigra Pars Reticulata: A New Mechanism of Pharmacoresistance

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Society for Neuroscience, 2011

Published in: The Journal of Neuroscience, 31 (2011) 45, Seite 16423-16434
Saskia Kücker; Kathrin Töllner; Marion Piechotta; Manuela Gernert

Kindling as a model of temporal lobe epilepsy induces bilateral changes in spontaneous striatal activity

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2010

Published in: Neurobiology of Disease, 37 (2010) 3, Seite 661-672
Bennay, Mustapha; Gernert, Manuela; Schwabe, Kerstin; Enkel, Thomas; Koch, Michael

Neonatal medial prefrontal cortex lesion enhances the sensitivity of the mesoaccumbal dopamine system

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Wiley, 2004

Published in: European Journal of Neuroscience, 19 (2004) 12, Seite 3277-3290
Gernert, Manuela; Fedrowitz, Maren; Wlaz, Piotr; Löscher, Wolfgang

Subregional changes in discharge rate, pattern, and drug sensitivity of putative GABAergic nigral neurons in the kindling model of epilepsy

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Wiley, 2004

Published in: European Journal of Neuroscience, 20 (2004) 9, Seite 2377-2386
Gernert, Manuela; Hamann, Melanie; Bennay, Mustapha; Löscher, Wolfgang; Richter, Angelika

Deficit of Striatal Parvalbumin-Reactive GABAergic Interneurons and Decreased Basal Ganglia Output in a Genetic Rodent Model of Idiopathic Paroxysmal Dystonia

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Society for Neuroscience, 2000

Published in: The Journal of Neuroscience, 20 (2000) 18, Seite 7052-7058
Bloms-Funke, Petra; Gernert, Manuela; Ebert, Ulrich; Löscher, Wolfgang

Extracellular single-unit recordings of piriform cortex neurons in rats: Influence of different types of anesthesia and characterization of neurons by pharmacological manipulation of serotonin receptors

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Wiley, 1999

Published in: Journal of Neuroscience Research, 55 (1999) 5, Seite 608-619
Gernert, Manuela; Richter, Angelika; Rundfeldt, Chris; Löscher, Wolfgang

Quantitative EEG analysis of depth electrode recordings from several brain regions of mutant hamsters with paroxysmal dystonia discloses frequency changes in the basal ganglia

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Wiley, 1998

Published in: Movement Disorders, 13 (1998) 3, Seite 509-521
Ebert, Ulrich; Gernert, Manuela; Löscher, Wolfgang; Richter, Angelika

Abnormal c-fos expression in the lateral habenula during dystonic attacks in a hamster model of idiopathic dystonia

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Elsevier BV, 1996

Published in: Brain Research, 728 (1996) 1, Seite 125-129
Niko Hensel; Svetlana Baskal; Lisa Marie Walter; Hella Brinkmann; Manuela Gernert; Peter Claus

ERK and ROCK functionally interact in a signaling network that is compensationally upregulated in Spinal Muscular Atrophy

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2017

Published in: Neurobiology of Disease, 108 (2017), Seite 352-361
Handreck, Annelie; Backofen-Wehrhahn, Bianca; Bröer, Sonja; Löscher, Wolfgang; Gernert, Manuela

Anticonvulsant Effects by Bilateral and Unilateral Transplantation of GABA-Producing Cells into the Subthalamic Nucleus in an Acute Seizure Model

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SAGE Publications, 2014

Published in: Cell Transplantation, 23 (2014) 1, Seite 111-132
Sonja Bröer; Bianca Backofen-Wehrhahn; Marion Bankstahl; Laura Gey; Manuela Gernert; Wolfgang Löscher

Vigabatrin for focal drug delivery in epilepsy: Bilateral microinfusion into the subthalamic nucleus is more effective than intranigral or systemic administration in a rat seizure model

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2012

Published in: Neurobiology of Disease, 46 (2012) 2, Seite 362-376
Marc W. Nolte; Wolfgang Löscher; Christiane Herden; William J. Freed; Manuela Gernert

Benefits and risks of intranigral transplantation of GABA-producing cells subsequent to the establishment of kindling-induced seizures

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2008

Published in: Neurobiology of Disease, 31 (2008) 3, Seite 342-354
Hamann, Melanie; Bennay, Mustapha; Gernert, Manuela; Schwabe, Kerstin; Koch, Michael; Richter, Angelika

Decreased density of amygdaloid parvalbumin-positive interneurons and behavioral changes in dystonic hamsters (Mesocricetus auratus)

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American Psychological Association (APA), 2008

Published in: Behavioral Neuroscience, 122 (2008) 1, Seite 36-43
Gernert, Manuela; Bennay, Mustapha; Fedrowitz, Maren; Rehders, Jan H.; Richter, Angelika

Altered Discharge Pattern of Basal Ganglia Output Neurons in an Animal Model of Idiopathic Dystonia

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Society for Neuroscience, 2002

Published in: The Journal of Neuroscience, 22 (2002) 16, Seite 7244-7253
Fedrowitz, Maren; Hamann, Melanie; Rehders, Jan H.; Richter, Angelika; Gernert, Manuela

Effects of locally administered pentylenetetrazole on nigral single unit activity and severity of dystonia in a genetic model of paroxysmal dystonia

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Wiley, 2002

Published in: Journal of Neuroscience Research, 68 (2002) 5, Seite 595-603
MacKeigan, Devlin; Feja, Malte; Meller, Sebastian; Deking, Lillian; Javadova, Amina; Veenhuis, Alva; Felmy, Felix; Gernert, Manuela

Long-lasting antiseizure effects of chronic intrasubthalamic convection-enhanced delivery of valproate

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Elsevier BV, 2023

Published in: Neurobiology of Disease, 187 (2023), Seite 106321

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