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König, Christina; Braune, Stephan; Roberts, Jason A.; Nierhaus, Axel; Steinmetz, Oliver M.; Baehr, Michael; Frey, Otto R.; Langebrake, Claudia; Kluge, StefanPopulation pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysisView onlineSchließen
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Published in: Journal of Antimicrobial Chemotherapy, 72 (2017) 5, Seite 1433-1440
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Hove, Michael J.; Stelzer, Johannes; Nierhaus, Till; Thiel, Sabrina D.; Gundlach, Christopher; Margulies, Daniel S.; Van Dijk, Koene R. A.; Turner, Robert; Keller, Peter E.; Merker, BjörnBrain Network Reconfiguration and Perceptual Decoupling During an Absorptive State of ConsciousnessView onlineSchließen
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Published in: Cerebral Cortex, 26 (2016) 7, Seite 3116-3124
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Achenbach, John; Jahnz, Michael; Bethge, Lucas; Paal, Krisztina; Jung, Maria; Schuster, Maja; Albrecht, Renate; Jarosch, Florian; Nierhaus, Knud H.; Klussmann, SvenOutwitting EF-Tu and the ribosome: translation with d-amino acidsView onlineSchließen
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Published in: Nucleic Acids Research, 43 (2015) 12, Seite 5687-5698
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Atanackovic, Djordje; Pollok, Kristina; Faltz, Christiane; Boeters, Ina; Jung, Roman; Nierhaus, Alexander; Braumann, Klaus-Michael; Hossfeld, Dieter Kurt; Hegewisch-Becker, SusannaPatients with solid tumors treated with high-temperature whole body hyperthermia show a redistribution of naive/memory T-cell subtypesView onlineSchließen
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Published in: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 290 (2006) 3, Seite R585-R594
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Sakr, Yasser; Bauer, Michael; Nierhaus, Axel; Kluge, Stefan; Schumacher, Ulricke; Putensen, Christian; Fichtner, Falk; Petros, Sirak; Scheer, Christian; Jaschinski, Ulrich; Tanev, Ivan; Jacob, David; Weiler, Norbert; Schulze, P. Christian; Fiedler, Fritz; Kapfer, Barbara; Brunkhorst, Frank; Lautenschlaeger, Ingmar; Wartenberg, Katja; Utzolino, Stefan; Briegel, Josef; Moerer, Onnen; Bischoff, Petra; Zarbock, Alexander; [...]Randomized controlled multicentre study of albumin replacement therapy in septic shock (ARISS): protocol for a randomized controlled trialView onlineSchließen
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Published in: Trials, 21 (2020) 1
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Kalvelage, Christina; Zacharowski, Kai; Bauhofer, Artur; Gockel, Ulrich; Adamzik, Michael; Nierhaus, Axel; Kujath, Peter; Eckmann, Christian; Pletz, Mathias W.; Bracht, Hendrik; Simon, Tim-Philipp; Winkler, Michael; Kindgen-Milles, Detlef; Albertsmeier, Markus; Weigand, Markus; Ellger, Björn; Ragaller, Maximilian; Ullrich, Roman; Marx, GernotPersonalized medicine with IgGAM compared with standard of care for treatment of peritonitis after infectious source control (the PEPPER trial): study protocol for a randomized controlled trialView onlineSchließen
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Published in: Trials, 20 (2019) 1
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Rahmel, Tim; Kraft, Felix; Haberl, Helge; Achtzehn, Ute; Brandenburger, Timo; Neb, Holger; Jarczak, Dominik; Dietrich, Maximilian; Magunia, Harry; Zimmer, Frieda; Basten, Jale; Landgraf, Claudia; Koch, Thea; Zacharowski, Kai; Weigand, Markus A.; Rosenberger, Peter; Ullrich, Roman; Meybohm, Patrick; Nierhaus, Axel; Kindgen-Milles, Detlef; Timmesfeld, Nina; Adamzik, MichaelIntravenous IgM-enriched immunoglobulins in critical COVID-19: a multicentre propensity-weighted cohort studyView onlineSchließen
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Published in: Critical Care, 26 (2022) 1
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Bauer, Michael; Weyland, Andreas; Marx, Gernot; Bloos, Frank; Weber, Stephan; Weiler, Norbert; Kluge, Stefan; Diers, Anja; Simon, Tim Philipp; Lautenschläger, Ingmar; Gründling, Matthias; Jaschinski, Ulrich; Simon, Philipp; Nierhaus, Axel; Moerer, Onnen; Reill, Lorenz; Jörres, Achim; Guo, Renfeng; Loeffler, Markus; Reinhart, Konrad; Riedemann, NielsEfficacy and Safety of Vilobelimab (IFX-1), a Novel Monoclonal Anti-C5a Antibody, in Patients With Early Severe Sepsis or Septic Shock—A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase IIa Trial (SCIENS Study)View onlineSchließen
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Published in: Critical Care Explorations, 3 (2021) 11, Seite e0577
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Brehm, Thomas Theo; Heyer, Andreas; Roedl, Kevin; Jarczak, Dominik; Nierhaus, Axel; Nentwich, Michael F; van der Meirschen, Marc; Schultze, Alexander; Christner, Martin; Fiedler, Walter; Kröger, Nicolaus; Huber, Tobias B; Klose, Hans; Sterneck, Martina; Jordan, Sabine; Kreuels, Benno; Schmiedel, Stefan; Addo, Marylyn M; Huber, Samuel; Lohse, Ansgar W; Kluge, Stefan; Schulze zur Wiesch, JulianPatient Characteristics and Clinical Course of COVID-19 Patients Treated at a German Tertiary Center during the First and Second Waves in the Year 2020View onlineSchließen
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Published in: Journal of Clinical Medicine, 10 (2021) 11, Seite 2274
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Keh, Didier; Trips, Evelyn; Marx, Gernot; Wirtz, Stefan P.; Abduljawwad, Emad; Bercker, Sven; Bogatsch, Holger; Briegel, Josef; Engel, Christoph; Gerlach, Herwig; Goldmann, Anton; Kuhn, Sven-Olaf; Hüter, Lars; Meier-Hellmann, Andreas; Nierhaus, Axel; Kluge, Stefan; Lehmke, Josefa; Loeffler, Markus; Oppert, Michael; Resener, Kerstin; Schädler, Dirk; Schuerholz, Tobias; Simon, Philipp; Weiler, Norbert; [...]Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis : The HYPRESS Randomized Clinical Trial : The HYPRESS Randomized Clinical TrialView onlineSchließen
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Published in: JAMA, 316 (2016) 17, Seite 1775
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Maaß, Henrike; Ynga-Durand, Mario; Milošević, Marko; Krstanović, Fran; Matešić, Marina Pribanić; Žuža, Iva; Jonjić, Stipan; Brizić, Ilija; Šustić, Alan; Bloos, Frank; Marx, Gernot; Jaschinski, Ulrich; Reinhart, Konrad; Spies, Claudia; Reil, Lorenz; Putensen, Christian; Ragaller, Maximilian; Utzlino, Stefan; Mörer, Onnen; Gründling, Matthias; Kluge, Stefan; Nierhaus, Axel; Welte, Tobias; Bauer, Michael; [...]Serum cytokine dysregulation signatures associated with COVID-19 outcomes in high mortality intensive care unit cohorts across pandemic waves and variantsView onlineSchließen
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Published in: Scientific Reports, 14 (2024) 1
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; Stefan Kluge; Alexander Zarbock; Patrick Meybohm; Christian Putensen; Stefan Hagel; Mathias W Pletz; Michael Bauer; Christian Jung; Markus A Weigand; Thorsten Brenner; Markus Heim; Stefan Münster; Sven Bercker; Sandra Fiedler; Frank Bloos; Maria Deja; Christian Ertmer; Peter Rosenberger; Helene Häberle; Jochen Dutzmann; Charlotte Ling; Andreas Güldner; Johannes Ehler; [...]Effect of acyclovir therapy on the outcome of mechanically ventilated patients with lower respiratory tract infection and detection of herpes simplex virus in bronchoalveolar lavage: protocol for a multicentre, randomised controlled trial (HerpMV)View onlineSchließen
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Published in: BMJ Open, 14 (2024) 4
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Hagel, Stefan; Bach, Friedhelm; Brenner, Thorsten; Bracht, Hendrik; Brinkmann, Alexander; Annecke, Thorsten; Hohn, Andreas; Weigand, Markus Alexander; Michels, Guido; Kluge, Stefan; Nierhaus, Axel; Jarczak, Dominik; König, Christina; Weismann, Dirk; Frey, Otto; Witzke, Dominic; Müller, Carsten; Bauer, Michael; Kiehntopf, Michael; Neugebauer, Sophie; Lehmann, Thomas; Roberts, Jason A.; Pletz, Mathias W.; Braune, Anke; [...]Correction to: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trialView onlineSchließen
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Published in: Intensive Care Medicine, 48 (2022) 5, Seite 646-647
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Hagel, Stefan; Bach, Friedhelm; Brenner, Thorsten; Bracht, Hendrik; Brinkmann, Alexander; Annecke, Thorsten; Hohn, Andreas; Weigand, Markus; Michels, Guido; Kluge, Stefan; Nierhaus, Axel; Jarczak, Dominik; König, Christina; Weismann, Dirk; Frey, Otto; Witzke, Dominic; Müller, Carsten; Bauer, Michael; Kiehntopf, Michael; Neugebauer, Sophie; Lehmann, Thomas; Roberts, Jason A.; Pletz, Mathias W.; Braune, Anke; [...]Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trialView onlineSchließen
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Published in: Intensive Care Medicine, 48 (2022) 3, Seite 311-321
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Hawchar, Fatime; Tomescu, Dana; Träger, Karl; Joskowiak, Dominik; Kogelmann, Klaus; Soukup, Jens; Friesecke, Singrun; Jacob, David; Gummert, Jan; Faltlhauser, Andreas; Aucella, Filippo; van Tellingen, Martijn; Malbrain, Manu L. N. G.; Bogdanski, Ralph; Weiss, Günter; Herbrich, Andreas; Utzolino, Stefan; Nierhaus, Axel; Baumann, Andreas; Hartjes, Andreas; Henzler, Dietrich; Grigoryev, Evgeny; Fritz, Harald; Bach, Friedhelm; [...]Hemoadsorption in the critically ill—Final results of the International CytoSorb RegistryView onlineSchließen
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Published in: PLOS ONE, 17 (2022) 10, Seite e0274315
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David, Sascha; Bode, Christian; Stahl, Klaus; Schmidt, Julius; Seeliger, Benjamin; Pape, Thorben; Schmidt, Bernhard; Hoeper, Marius M.; Wedemeyer, Heiner; Welte, Tobias; Schmidt-Ott, Kai; Wendel Garcia, Pedro David; Hofmänner, Daniel A.; Andermatt, Rea; Schuepbach, Reto; Bankova, Andriyana; Gillmann, Hans-Joerg; Stueber, Thomas; Jung, Carolin; Gerdes, Andre; Putensen, Christian; Sauer, Andrea; Wild, Lennart; Lehmann, Felix; [...]EXCHANGE-2: investigating the efficacy of add-on plasma exchange as an adjunctive strategy against septic shock—a study protocol for a randomized, prospective, multicenter, open-label, controlled, parallel-group trialView onlineSchließen
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Published in: Trials, 24 (2023) 1
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Babayan, Anahit; Erbey, Miray; Kumral, Deniz; Reinelt, Janis D.; Reiter, Andrea M. F.; Röbbig, Josefin; Schaare, H. Lina; Uhlig, Marie; Anwander, Alfred; Bazin, Pierre-Louis; Horstmann, Annette; Lampe, Leonie; Nikulin, Vadim V.; Okon-Singer, Hadas; Preusser, Sven; Pampel, André; Rohr, Christiane S.; Sacher, Julia; Thöne-Otto, Angelika; Trapp, Sabrina; Nierhaus, Till; Altmann, Denise; Arelin, Katrin; Blöchl, Maria; [...]A mind-brain-body dataset of MRI, EEG, cognition, emotion, and peripheral physiology in young and old adultsView onlineSchließen
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Published in: Scientific Data, 6 (2019) 1
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Florescu, Simin; Stanciu, Delia; Zaharia, Mihaela; Kosa, Alma; Codreanu, Daniel; Kidwai, Aneela; Masood, Sobia; Kaye, Callum; Coutts, Amanda; MacKay, Lynn; Summers, Charlotte; Polgarova, Petra; Farahi, Neda; Fox, Eleonore; McWilliam, Stephen; Hawcutt, Daniel; Rad, Laura; O’Malley, Laura; Whitbread, Jennifer; Jones, Dawn; Dore, Rachael; Saunderson, Paula; Kelsall, Olivia; Cowley, Nicholas; [...]Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical TrialView onlineSchließen
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Published in: JAMA, 329 (2023) 1, Seite 39
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Florescu, Simin; Stanciu, Delia; Zaharia, Mihaela; Kosa, Alma; Codreanu, Daniel; Kidwai, Aneela; Masood, Sobia; Kaye, Callum; Coutts, Amanda; MacKay, Lynn; Summers, Charlotte; Polgarova, Petra; Farahi, Neda; Fox, Eleonore; McWilliam, Stephen; Hawcutt, Daniel; Rad, Laura; O’Malley, Laura; Whitbread, Jennifer; Jones, Dawn; Dore, Rachael; Saunderson, Paula; Kelsall, Olivia; Cowley, Nicholas; [...]Effect of Antiplatelet Therapy on Survival and Organ Support–Free Days in Critically Ill Patients With COVID-19 : A Randomized Clinical Trial : A Randomized Clinical TrialView onlineSchließen
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Published in: JAMA, 327 (2022) 13, Seite 1247
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Florescu, Simin; Stanciu, Delia; Zaharia, Mihaela; Kosa, Alma; Codreanu, Daniel; Fareed, Komal; Kidwai, Aneela; Kaye, Callum; Coutts, Amanda; MacKay, Lynn; Summers, Charlotte; Polgarova, Petra; Farahi, Neda; Fox, Eleonore; Sapsford, David; Bongaerts, Katherine; Featherstone, Peter; Ng, Anthony; McWilliam, Stephen; Hawcutt, Daniel; Rad, Laura; O’Malley, Laura; Whitbread, Jennifer; Jones, Dawn; [...]Intravenous Vitamin C for Patients Hospitalized With COVID-19 : Two Harmonized Randomized Clinical Trials : Two Harmonized Randomized Clinical TrialsView onlineSchließen
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Published in: JAMA, 330 (2023) 18, Seite 1745