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Fakhiri, Julia [Author] ; Kalle, Christof von [Degree supervisor]

With small viruses come giant responsibilities : next-generation parvoviral vectors for human gene therapy with extended packaging capacity and enhanced safety profile

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Heidelberg, 08 Nov. 2019
Becker, Jonas [Author]; Fakhiri, Julia [Author]; Grimm, Dirk [Author]

Fantastic AAV gene therapy cectors and how to find them : random diversification, rational design and machine learning

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3 July 2022

Published in: Pathogens ; 11(2022), 7, Artikel-ID 756, Seite 1-30
Große, Stefanie [Author]; Börner, Kathleen [Author]; Fakhiri, Julia [Author]; Laketa, Vibor [Author]; Wiedtke, Ellen [Author]; Gunkel, Manuel [Author]; Grimm, Dirk [Author]

Relevance of assembly-activating protein for adeno-associated virus vector production and capsid protein stability in mammalian and insect cells

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2017

Published in: Journal of virology ; 91(2017,20) Artikel-Nummer e01198-17, 20 Seiten
Fakhiri, Julia [Author] ; Kalle, Christof von [Degree supervisor]

With small viruses come giant responsibilities - Next-generation parvoviral vectors for human gene therapy with extended packaging capacity and enhanced safety profile

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Heidelberg: Universitätsbibliothek Heidelberg, 2019
Fakhiri, Julia; Grimm, Dirk

Best of most possible worlds: Hybrid gene therapy vectors based on parvoviruses and heterologous viruses

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Elsevier BV, 2021

Published in: Molecular Therapy, 29 (2021) 12, Seite 3359-3382
Becker, Jonas; Fakhiri, Julia; Grimm, Dirk

Fantastic AAV Gene Therapy Vectors and How to Find Them—Random Diversification, Rational Design and Machine Learning

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MDPI AG, 2022

Published in: Pathogens, 11 (2022) 7, Seite 756
Tabatabai, Julia; Fakhiri, Julia; Meyburg, Jochen; Linse, Kai-Philipp; Xu, Man; Söderlund-Venermo, Maria; Grimm, Dirk; Schnitzler, Paul

Severe Human Bocavirus 1 Respiratory Tract Infection in an Immunodeficient Child With Fatal Outcome

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Ovid Technologies (Wolters Kluwer Health), 2019

Published in: Pediatric Infectious Disease Journal, 38 (2019) 9, Seite e219-e222
Fakhiri, Julia; Schneider, Marc; Kailasan, Shweta; Meister, Michael; McKenna, Mavis A.; Yan, Ziying; Qiu, Jianming; Grimm, Dirk

254. New Chimeric Gene Therapy Vectors Based on Four Different Mammalian Bocaviruses

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Elsevier BV, 2016

Published in: Molecular Therapy, 24 (2016), Seite S100
Fakhiri, Julia; Linse, Kai-Philipp; Mietzsch, Mario; Xu, Man; Schneider, Marc A.; Meister, Michael; Schildgen, Oliver; Schnitzler, Paul; Soderlund-Venermo, Maria; Agbandje-McKenna, Mavis; Grimm, Dirk

Impact of Natural or Synthetic Singletons in the Capsid of Human Bocavirus 1 on Particle Infectivity and Immunoreactivity

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American Society for Microbiology, 2020

Published in: Journal of Virology, 94 (2020) 11
Hoffmann, Mareike D; Aschenbrenner, Sabine; Grosse, Stefanie; Rapti, Kleopatra; Domenger, Claire; Fakhiri, Julia; Mastel, Manuel; Börner, Kathleen; Eils, Roland; Grimm, Dirk; Niopek, Dominik

Cell-specific CRISPR–Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins

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Oxford University Press (OUP), 2019

Published in: Nucleic Acids Research, 47 (2019) 13, Seite e75-e75
Grosse, Stefanie; Penaud-Budloo, Magalie; Herrmann, Anne-Kathrin; Börner, Kathleen; Fakhiri, Julia; Laketa, Vibor; Krämer, Chiara; Wiedtke, Ellen; Gunkel, Manuel; Ménard, Lucie; Ayuso, Eduard; Grimm, Dirk

Relevance of Assembly-Activating Protein for Adeno-associated Virus Vector Production and Capsid Protein Stability in Mammalian and Insect Cells

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American Society for Microbiology, 2017

Published in: Journal of Virology, 91 (2017) 20
Yu, Jennifer Chun; Mietzsch, Mario; Singh, Amriti; Jimenez Ybargollin, Alberto; Kailasan, Shweta; Chipman, Paul; Bhattacharya, Nilakshee; Fakhiri, Julia; Grimm, Dirk; Kapoor, Amit; Kučinskaitė-Kodzė, Indrė; Žvirblienė, Aurelija; Söderlund-Venermo, Maria; McKenna, Robert; Agbandje-McKenna, Mavis

Characterization of the GBoV1 Capsid and Its Antibody Interactions

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MDPI AG, 2021

Published in: Viruses, 13 (2021) 2, Seite 330
Krooss, Simon Alexander; Dai, Zhen; Schmidt, Florian; Rovai, Alice; Fakhiri, Julia; Dhingra, Akshay; Yuan, Qinggong; Yang, Taihua; Balakrishnan, Asha; Steinbrück, Lars; Srivaratharajan, Sangar; Manns, Michael Peter; Schambach, Axel; Grimm, Dirk; Bohne, Jens; Sharma, Amar Deep; Büning, Hildegard; Ott, Michael

Ex Vivo/In vivo Gene Editing in Hepatocytes Using “All-in-One” CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template

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Elsevier BV, 2020

Published in: iScience, 23 (2020) 1, Seite 100764
Fakhiri, Julia; Schneider, Marc A.; Puschhof, Jens; Stanifer, Megan; Schildgen, Verena; Holderbach, Stefan; Voss, Yannik; El Andari, Jihad; Schildgen, Oliver; Boulant, Steeve; Meister, Michael; Clevers, Hans; Yan, Ziying; Qiu, Jianming; Grimm, Dirk

Novel Chimeric Gene Therapy Vectors Based on Adeno-Associated Virus and Four Different Mammalian Bocaviruses

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Elsevier BV, 2019

Published in: Molecular Therapy - Methods & Clinical Development, 12 (2019), Seite 202-222
Bubeck, Felix; Hoffmann, Mareike D.; Harteveld, Zander; Aschenbrenner, Sabine; Bietz, Andreas; Waldhauer, Max C.; Börner, Kathleen; Fakhiri, Julia; Schmelas, Carolin; Dietz, Laura; Grimm, Dirk; Correia, Bruno E.; Eils, Roland; Niopek, Dominik

Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9

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Springer Science and Business Media LLC, 2018

Published in: Nature Methods, 15 (2018) 11, Seite 924-927
Börner, Kathleen; Kienle, Eike; Huang, Lin-Ya; Weinmann, Jonas; Sacher, Anna; Bayer, Philipp; Stüllein, Christian; Fakhiri, Julia; Zimmermann, Laura; Westhaus, Adrian; Beneke, Jürgen; Beil, Nina; Wiedtke, Ellen; Schmelas, Carolin; Miltner, Dominik; Rau, Alexander; Erfle, Holger; Kräusslich, Hans-Georg; Müller, Martin; Agbandje-McKenna, Mavis; Grimm, Dirk

Pre-arrayed Pan-AAV Peptide Display Libraries for Rapid Single-Round Screening

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Elsevier BV, 2020

Published in: Molecular Therapy, 28 (2020) 4, Seite 1016-1032
El Andari, Jihad; Renaud-Gabardos, Edith; Tulalamba, Warut; Weinmann, Jonas; Mangin, Louise; Pham, Quang Hong; Hille, Susanne; Bennett, Antonette; Attebi, Esther; Bourges, Emanuele; Leborgne, Christian; Guerchet, Nicolas; Fakhiri, Julia; Krämer, Chiara; Wiedtke, Ellen; McKenna, Robert; Guianvarc’h, Laurence; Toueille, Magali; Ronzitti, Giuseppe; Hebben, Matthias; Mingozzi, Federico; VandenDriessche, Thierry; Agbandje-McKenna, Mavis; Müller, Oliver J.; [...]

Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders

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American Association for the Advancement of Science (AAAS), 2022

Published in: Science Advances, 8 (2022) 38

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