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Visnes, Torkild; Benítez-Buelga, Carlos; Cázares-Körner, Armando; Sanjiv, Kumar; Hanna, Bishoy M F; Mortusewicz, Oliver; Rajagopal, Varshni; Albers, Julian J; Hagey, Daniel W; Bekkhus, Tove; Eshtad, Saeed; Baquero, Juan Miguel; Masuyer, Geoffrey; Wallner, Olov; Müller, Sarah; Pham, Therese; Göktürk, Camilla; Rasti, Azita; Suman, Sharda; Torres-Ruiz, Raúl; Sarno, Antonio; Wiita, Elisée; Homan, Evert J; Karsten, Stella; [...]Targeting OGG1 arrests cancer cell proliferation by inducing replication stressView onlineSchließen
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Published in: Nucleic Acids Research
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Gad, Helge; Koolmeister, Tobias; Jemth, Ann-Sofie; Eshtad, Saeed; Jacques, Sylvain A.; Ström, Cecilia E.; Svensson, Linda M.; Schultz, Niklas; Lundbäck, Thomas; Einarsdottir, Berglind Osk; Saleh, Aljona; Göktürk, Camilla; Baranczewski, Pawel; Svensson, Richard; Berntsson, Ronnie P.-A.; Gustafsson, Robert; Strömberg, Kia; Sanjiv, Kumar; Jacques-Cordonnier, Marie-Caroline; Desroses, Matthieu; Gustavsson, Anna-Lena; Olofsson, Roger; Johansson, Fredrik; Homan, Evert J.; [...]Correction: Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP poolView onlineSchließen
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Published in: Nature
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Gad, Helge; Koolmeister, Tobias; Jemth, Ann-Sofie; Eshtad, Saeed; Jacques, Sylvain A.; Ström, Cecilia E.; Svensson, Linda M.; Schultz, Niklas; Lundbäck, Thomas; Einarsdottir, Berglind Osk; Saleh, Aljona; Göktürk, Camilla; Baranczewski, Pawel; Svensson, Richard; Berntsson, Ronnie P.-A.; Gustafsson, Robert; Strömberg, Kia; Sanjiv, Kumar; Jacques-Cordonnier, Marie-Caroline; Desroses, Matthieu; Gustavsson, Anna-Lena; Olofsson, Roger; Johansson, Fredrik; Homan, Evert J.; [...]MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP poolView onlineSchließen
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Published in: Nature
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Maestre-Reyna, Manuel; Wang, Po-Hsun; Nango, Eriko; Hosokawa, Yuhei; Saft, Martin; Furrer, Antonia; Yang, Cheng-Han; Gusti Ngurah Putu, Eka Putra; Wu, Wen-Jin; Emmerich, Hans-Joachim; Caramello, Nicolas; Franz-Badur, Sophie; Yang, Chao; Engilberge, Sylvain; Wranik, Maximilian; Glover, Hannah Louise; Weinert, Tobias; Wu, Hsiang-Yi; Lee, Cheng-Chung; Huang, Wei-Cheng; Huang, Kai-Fa; Chang, Yao-Kai; Liao, Jiahn-Haur; Weng, Jui-Hung; [...]Visualizing the DNA repair process by a photolyase at atomic resolutionView onlineSchließen
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Published in: Science
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Wang, Joshua M.; Hong, Runyu; Demicco, Elizabeth G.; Tan, Jimin; Lazcano, Rossana; Moreira, Andre L.; Li, Yize; Calinawan, Anna; Razavian, Narges; Schraink, Tobias; Gillette, Michael A.; Omenn, Gilbert S.; An, Eunkyung; Rodriguez, Henry; Tsirigos, Aristotelis; Ruggles, Kelly V.; Ding, Li; Robles, Ana I.; Mani, D.R.; Rodland, Karin D.; Lazar, Alexander J.; Liu, Wenke; Fenyö, David; Aguet, François; [...]Deep learning integrates histopathology and proteogenomics at a pan-cancer levelView onlineSchließen
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Published in: Cell Reports Medicine
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Satpathy, Shankha; Krug, Karsten; Jean Beltran, Pierre M.; Savage, Sara R.; Petralia, Francesca; Kumar-Sinha, Chandan; Dou, Yongchao; Reva, Boris; Kane, M. Harry; Avanessian, Shayan C.; Vasaikar, Suhas V.; Krek, Azra; Lei, Jonathan T.; Jaehnig, Eric J.; Omelchenko, Tatiana; Geffen, Yifat; Bergstrom, Erik J.; Stathias, Vasileios; Christianson, Karen E.; Heiman, David I.; Cieslik, Marcin P.; Cao, Song; Song, Xiaoyu; Ji, Jiayi; [...]A proteogenomic portrait of lung squamous cell carcinomaView onlineSchließen
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Published in: Cell
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Fishbein, Lauren; Leshchiner, Ignaty; Walter, Vonn; Danilova, Ludmila; Robertson, A. Gordon; Johnson, Amy R.; Lichtenberg, Tara M.; Murray, Bradley A.; Ghayee, Hans K.; Else, Tobias; Ling, Shiyun; Jefferys, Stuart R.; de Cubas, Aguirre A.; Wenz, Brandon; Korpershoek, Esther; Amelio, Antonio L.; Makowski, Liza; Rathmell, W. Kimryn; Gimenez-Roqueplo, Anne-Paule; Giordano, Thomas J.; Asa, Sylvia L.; Tischler, Arthur S.; Pacak, Karel; Nathanson, Katherine L.; [...]Comprehensive Molecular Characterization of Pheochromocytoma and ParagangliomaView onlineSchließen
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Published in: Cancer Cell
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Zheng, Siyuan; Cherniack, Andrew D.; Dewal, Ninad; Moffitt, Richard A.; Danilova, Ludmila; Murray, Bradley A.; Lerario, Antonio M.; Else, Tobias; Knijnenburg, Theo A.; Ciriello, Giovanni; Kim, Seungchan; Assie, Guillaume; Morozova, Olena; Akbani, Rehan; Shih, Juliann; Hoadley, Katherine A.; Choueiri, Toni K.; Waldmann, Jens; Mete, Ozgur; Robertson, A. Gordon; Wu, Hsin-Ta; Raphael, Benjamin J.; Shao, Lina; Meyerson, Matthew; [...]Comprehensive Pan-Genomic Characterization of Adrenocortical CarcinomaView onlineSchließen
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Published in: Cancer Cell
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Zheng, Siyuan; Cherniack, Andrew D.; Dewal, Ninad; Moffitt, Richard A.; Danilova, Ludmila; Murray, Bradley A.; Lerario, Antonio M.; Else, Tobias; Knijnenburg, Theo A.; Ciriello, Giovanni; Kim, Seungchan; Assie, Guillaume; Morozova, Olena; Akbani, Rehan; Shih, Juliann; Hoadley, Katherine A.; Choueiri, Toni K.; Waldmann, Jens; Mete, Ozgur; Robertson, A. Gordon; Wu, Hsin-Ta; Raphael, Benjamin J.; Shao, Lina; Meyerson, Matthew; [...]Comprehensive Pan-Genomic Characterization of Adrenocortical CarcinomaView onlineSchließen
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Published in: Cancer Cell
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Agrawal, Nishant; Akbani, Rehan; Aksoy, B. Arman; Ally, Adrian; Arachchi, Harindra; Asa, Sylvia L.; Auman, J. Todd; Balasundaram, Miruna; Balu, Saianand; Baylin, Stephen B.; Behera, Madhusmita; Bernard, Brady; Beroukhim, Rameen; Bishop, Justin A.; Black, Aaron D.; Bodenheimer, Tom; Boice, Lori; Bootwalla, Moiz S.; Bowen, Jay; Bowlby, Reanne; Bristow, Christopher A.; Brookens, Robin; Brooks, Denise; Bryant, Robert; [...]Integrated Genomic Characterization of Papillary Thyroid CarcinomaView onlineSchließen
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Published in: Cell
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Bakker, Mark K.; Kanning, Jos P.; Abraham, Gad; Martinsen, Amy E.; Winsvold, Bendik S.; Zwart, John-Anker; Bourcier, Romain; Sawada, Tomonobu; Koido, Masaru; Kamatani, Yoichiro; Morel, Sandrine; Amouyel, Philippe; Debette, Stéphanie; Bijlenga, Philippe; Berrandou, Takiy; Ganesh, Santhi K.; Bouatia-Naji, Nabila; Jones, Gregory; Bown, Matthew; Rinkel, Gabriel J.E.; Veldink, Jan H.; Ruigrok, Ynte M.; Hege Aamodt, Anne; Heidi Skogholt, Anne; [...]Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical HeterogeneityView onlineSchließen
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Published in: Stroke
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Rheinbay, Esther; Nielsen, Morten Muhlig; Abascal, Federico; Wala, Jeremiah A.; Shapira, Ofer; Tiao, Grace; Hornshøj, Henrik; Hess, Julian M.; Juul, Randi Istrup; Lin, Ziao; Feuerbach, Lars; Sabarinathan, Radhakrishnan; Madsen, Tobias; Kim, Jaegil; Mularoni, Loris; Shuai, Shimin; Lanzós, Andrés; Herrmann, Carl; Maruvka, Yosef E.; Shen, Ciyue; Amin, Samirkumar B.; Bandopadhayay, Pratiti; Bertl, Johanna; Boroevich, Keith A.; [...]Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomesView onlineSchließen
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Published in: Nature
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Rheinbay, Esther; Nielsen, Morten Muhlig; Abascal, Federico; Wala, Jeremiah A.; Shapira, Ofer; Tiao, Grace; Hornshøj, Henrik; Hess, Julian M.; Juul, Randi Istrup; Lin, Ziao; Feuerbach, Lars; Sabarinathan, Radhakrishnan; Madsen, Tobias; Kim, Jaegil; Mularoni, Loris; Shuai, Shimin; Lanzós, Andrés; Herrmann, Carl; Maruvka, Yosef E.; Shen, Ciyue; Amin, Samirkumar B.; Bandopadhayay, Pratiti; Bertl, Johanna; Boroevich, Keith A.; [...]Analyses of non-coding somatic drivers in 2,658 cancer whole genomesView onlineSchließen
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Published in: Nature
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Bailey, Matthew H.; Meyerson, William U.; Dursi, Lewis Jonathan; Wang, Liang-Bo; Dong, Guanlan; Liang, Wen-Wei; Weerasinghe, Amila; Li, Shantao; Li, Yize; Kelso, Sean; Akbani, Rehan; Anur, Pavana; Bailey, Matthew H.; Buchanan, Alex; Chiotti, Kami; Covington, Kyle; Creason, Allison; Ding, Li; Ellrott, Kyle; Fan, Yu; Foltz, Steven; Getz, Gad; Hale, Walker; Haussler, David; [...]Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samplesView onlineSchließen
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Published in: Nature Communications
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Bailey, Matthew H.; Meyerson, William U.; Dursi, Lewis Jonathan; Wang, Liang-Bo; Dong, Guanlan; Liang, Wen-Wei; Weerasinghe, Amila; Li, Shantao; Li, Yize; Kelso, Sean; Akbani, Rehan; Anur, Pavana; Bailey, Matthew H.; Buchanan, Alex; Chiotti, Kami; Covington, Kyle; Creason, Allison; Ding, Li; Ellrott, Kyle; Fan, Yu; Foltz, Steven; Getz, Gad; Hale, Walker; Haussler, David; [...]Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samplesView onlineSchließen
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Published in: Nature Communications
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Gerstung, Moritz; Jolly, Clemency; Leshchiner, Ignaty; Dentro, Stefan C.; Gonzalez, Santiago; Rosebrock, Daniel; Mitchell, Thomas J.; Rubanova, Yulia; Anur, Pavana; Yu, Kaixian; Tarabichi, Maxime; Deshwar, Amit; Wintersinger, Jeff; Kleinheinz, Kortine; Vázquez-García, Ignacio; Haase, Kerstin; Jerman, Lara; Sengupta, Subhajit; Macintyre, Geoff; Malikic, Salem; Donmez, Nilgun; Livitz, Dimitri G.; Cmero, Marek; Demeulemeester, Jonas; [...]Author Correction: The evolutionary history of 2,658 cancersView onlineSchließen
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Published in: Nature
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Alexandrov, Ludmil B.; Kim, Jaegil; Haradhvala, Nicholas J.; Huang, Mi Ni; Tian Ng, Alvin Wei; Wu, Yang; Boot, Arnoud; Covington, Kyle R.; Gordenin, Dmitry A.; Bergstrom, Erik N.; Islam, S. M. Ashiqul; Lopez-Bigas, Nuria; Klimczak, Leszek J.; McPherson, John R.; Morganella, Sandro; Sabarinathan, Radhakrishnan; Wheeler, David A.; Mustonen, Ville; Alexandrov, Ludmil B.; Bergstrom, Erik N.; Boot, Arnoud; Boutros, Paul; Chan, Kin; Covington, Kyle R.; [...]Author Correction: The repertoire of mutational signatures in human cancerView onlineSchließen
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Published in: Nature
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Jiao, Wei; Atwal, Gurnit; Polak, Paz; Karlic, Rosa; Cuppen, Edwin; Al-Shahrour, Fatima; Atwal, Gurnit; Bailey, Peter J.; Biankin, Andrew V.; Boutros, Paul C.; Campbell, Peter J.; Chang, David K.; Cooke, Susanna L.; Deshpande, Vikram; Faltas, Bishoy M.; Faquin, William C.; Garraway, Levi; Getz, Gad; Grimmond, Sean M.; Haider, Syed; Hoadley, Katherine A.; Jiao, Wei; Kaiser, Vera B.; Karlic, Rosa; [...]Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patternsView onlineSchließen
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Published in: Nature Communications
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Jiao, Wei; Atwal, Gurnit; Polak, Paz; Karlic, Rosa; Cuppen, Edwin; Al-Shahrour, Fatima; Atwal, Gurnit; Bailey, Peter J.; Biankin, Andrew V.; Boutros, Paul C.; Campbell, Peter J.; Chang, David K.; Cooke, Susanna L.; Deshpande, Vikram; Faltas, Bishoy M.; Faquin, William C.; Garraway, Levi; Getz, Gad; Grimmond, Sean M.; Haider, Syed; Hoadley, Katherine A.; Jiao, Wei; Kaiser, Vera B.; Karlic, Rosa; [...]A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patternsView onlineSchließen
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Published in: Nature Communications
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Gerstung, Moritz; Jolly, Clemency; Leshchiner, Ignaty; Dentro, Stefan C.; Gonzalez, Santiago; Rosebrock, Daniel; Mitchell, Thomas J.; Rubanova, Yulia; Anur, Pavana; Yu, Kaixian; Tarabichi, Maxime; Deshwar, Amit; Wintersinger, Jeff; Kleinheinz, Kortine; Vázquez-García, Ignacio; Haase, Kerstin; Jerman, Lara; Sengupta, Subhajit; Macintyre, Geoff; Malikic, Salem; Donmez, Nilgun; Livitz, Dimitri G.; Cmero, Marek; Demeulemeester, Jonas; [...]The evolutionary history of 2,658 cancersView onlineSchließen
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Published in: Nature