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Ternette, Nicola; Yang, Ming; Laroyia, Mahima; Kitagawa, Mitsuhiro; O’Flaherty, Linda; Wolhulter, Kathryn; Igarashi, Kaori; Saito, Kaori; Kato, Keiko; Fischer, Roman; Berquand, Alexandre; Kessler, Benedikt M.; Lappin, Terry; Frizzell, Norma; Soga, Tomoyoshi; Adam, Julie; Pollard, Patrick J.Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase DeficiencyView onlineSchließen
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Published in: Cell Reports
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Kan, Lixin; Lounev, Vitali Y; Pignolo, Robert J.; Duan, Lishu; Liu, Yijie; Stock, Stuart R.; McGuire, Tammy L.; Lu, Bao; Gerard, Norma P.; Shore, Eileen M.; Kaplan, Frederick S.; Kessler, John A.Substance P signaling mediates BMP-dependent heterotopic ossificationView onlineSchließen
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Published in: Journal of Cellular Biochemistry
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Rand, Jamie Green; Yamauchi, Dave; Chaurasiya, Shyambabu; Zhang, Jianying; Pillai, Raju; Egelston, Colt; Kessler, Jonathan; Modi, Badri; Chong, Leslie; Seiz, Amanda; Selvaggi, Giovanni; Ede, Nick; Murga, Mireya; Martinez, Norma; Borisuthirattana, Wichanee; Meisen, Hans; Yost, Susan; Waisman, James; Stewart, Daphne; Mortimer, Joanne; Fong, Yuman; Yuan, YuanAbstract 6788: hNIS imaging data from a first-in-human trial of the oncolytic virus CF33-hNIS-antiPD-L1 in patients with triple negative breast cancerView onlineSchließen
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Published in: Cancer Research
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Yuan, Yuan; Rand, Jamie G.; Zhang, Jianying; Kessler, Jonathan; Modi, Badri; Pillai, Raju; Egelston, Colt A.; Chaurasiya, Shyambabu; Murga, Mireya; Tang, Aileen; Martinez, Norma; Meisen, Hans; Yamauchi, Dave; Yost, Susan E.; Chong, Leslie; Seiz, Amanda; Nixon, Bonnie; Ede, Nick; Waisman, James; Stewart, Daphne; Sedrak, Mina S.; Fong, YumanAbstract OT3-03-01: Phase I study of intratumoral administration of CF33-hNIS-antiPD-L1 (CHECKvacc) in patients with metastatic triple negative breast cancerView onlineSchließen
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Published in: Cancer Research
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Yuan, Yuan; Egelston, Colt; Colunga Flores, Oscar; Chaurasiya, Shyambabu; Lin, David; Chang, Helen; Chong, Leslie Mi Ok; Seiz, Amanda; Shah, Monil; Meisen, W. Hans; Tang, Aileen; Martinez, Norma; Pickett, Wichanee; Murga, Mireya; Yost, Susan E.; Stewart, Daphne; Zhang, Jianying; Ede, Nicholas; Modi, Badri; Kessler, Jonathan; Rand, Jamie; Fong, YumanCF33-hNIS-anti-PD-L1 oncolytic virus followed by trastuzumab-deruxtecan in a patient with metastatic triple negative breast cancer: a case studyView onlineSchließen
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Published in: Therapeutic Advances in Medical Oncology
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Yuan, Yuan; Zhang, Jianying; Kessler, Jonathan; Rand, Jamie; Modi, Badri; Chaurasiya, Shyambabu; Murga, Mireya; Tang, Aileen; Martinez, Norma; Meisen, Hans; Yamauchi, Dave; Yost, Susan Elaine; Chong, Leslie Mi Ok; Seiz, Amanda; Nixon, Bonnie; Ede, Nicholas; Waisman, James Ross; Stewart, Daphne B.; Mortimer, Joanne E.; Fong, YumanPhase I study of intratumoral administration of CF33-HNIS-antiPDL1 in patients with metastatic triple negative breast cancerView onlineSchließen
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Published in: Journal of Clinical Oncology
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Bardella, Chiara; El‐Bahrawy, Mona; Frizzell, Norma; Adam, Julie; Ternette, Nicola; Hatipoglu, Emine; Howarth, Kimberley; O'Flaherty, Linda; Roberts, Ian; Turner, Gareth; Taylor, Jennifer; Giaslakiotis, Konstantinos; Macaulay, Valentine M; Harris, Adrian L; Chandra, Ashish; Lehtonen, Heli J; Launonen, Virpi; Aaltonen, Lauri A; Pugh, Christopher W; Mihai, Radu; Trudgian, David; Kessler, Benedikt; Baynes, John W; Ratcliffe, Peter J; [...]Aberrant succination of proteins in fumarate hydratase‐deficient mice and HLRCC patients is a robust biomarker of mutation statusView onlineSchließen
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Published in: The Journal of Pathology
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Adam, Julie; Hatipoglu, Emine; O'Flaherty, Linda; Ternette, Nicola; Sahgal, Natasha; Lockstone, Helen; Baban, Dilair; Nye, Emma; Stamp, Gordon W.; Wolhuter, Kathryn; Stevens, Marcus; Fischer, Roman; Carmeliet, Peter; Maxwell, Patrick H.; Pugh, Chris W.; Frizzell, Norma; Soga, Tomoyoshi; Kessler, Benedikt M.; El-Bahrawy, Mona; Ratcliffe, Peter J.; Pollard, Patrick J.Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 SignalingView onlineSchließen
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Published in: Cancer Cell
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Adam, Julie; Ramracheya, Reshma; Chibalina, Margarita V.; Ternette, Nicola; Hamilton, Alexander; Tarasov, Andrei I.; Zhang, Quan; Rebelato, Eduardo; Rorsman, Nils J.G.; Martín-del-Río, Rafael; Lewis, Amy; Özkan, Gizem; Do, Hyun Woong; Spégel, Peter; Saitoh, Kaori; Kato, Keiko; Igarashi, Kaori; Kessler, Benedikt M.; Pugh, Christopher W.; Tamarit-Rodriguez, Jorge; Mulder, Hindrik; Clark, Anne; Frizzell, Norma; Soga, Tomoyoshi; [...]Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive DiabetesView onlineSchließen
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Published in: Cell Reports
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Guimarães-Costa, Raquel; Niérat, Marie-Cécile; Rivals, Isabelle; Morélot-Panzini, Capucine; Romero, Norma Beatriz; Menegaux, Fabrice; Salachas, François; Gonzalez-Bermejo, Jésus; Similowski, Thomas; Bruneteau, Gaëlle; del Mar Amador, Maria; Antoine, Jean Christophe; Arne-Bes, Marie Christine; Attali, Valérie; Beauvais, Katell; Brunaud-Danel, Veronique; Bruneteau, Gaelle; Camdessanche, Jean-Philippe; Camu, William; Carluer, Laurence; Cassereau, Julien; Chapart, Maud; Chenuel, Bruno; Chereau, Nathalie; [...]Implanted Phrenic Stimulation Impairs Local Diaphragm Myofiber Reinnervation in Amyotrophic Lateral SclerosisView onlineSchließen
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Published in: American Journal of Respiratory and Critical Care Medicine
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Ziyatdinov, Andrey; Torres, Jason; Alegre-Díaz, Jesús; Backman, Joshua; Mbatchou, Joelle; Turner, Michael; Gaynor, Sheila M.; Joseph, Tyler; Zou, Yuxin; Liu, Daren; Wade, Rachel; Staples, Jeffrey; Panea, Razvan; Popov, Alex; Bai, Xiaodong; Balasubramanian, Suganthi; Habegger, Lukas; Lanche, Rouel; Lopez, Alex; Maxwell, Evan; Jones, Marcus; García-Ortiz, Humberto; Ramirez-Reyes, Raul; Santacruz-Benítez, Rogelio; [...]Genotyping, sequencing and analysis of 140,000 adults from Mexico CityView onlineSchließen
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Published in: Nature
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Theodore, Deborah A.; Branche, Angela R.; Zhang, Lily; Graciaa, Daniel S.; Choudhary, Madhu; Hatlen, Timothy J.; Osman, Raadhiya; Babu, Tara M.; Robinson, Samuel T.; Gilbert, Peter B.; Follmann, Dean; Janes, Holly; Kublin, James G.; Baden, Lindsey R.; Goepfert, Paul; Gray, Glenda E.; Grinsztejn, Beatriz; Kotloff, Karen L.; Gay, Cynthia L.; Leav, Brett; Miller, Jacqueline; Hirsch, Ian; Sadoff, Jerald; Dunkle, Lisa M.; [...]Clinical and Demographic Factors Associated With COVID-19, Severe COVID-19, and SARS-CoV-2 Infection in Adults : A Secondary Cross-Protocol Analysis of 4 Randomized Clinical Trials : A Secondary Cross-Protocol Analysis of 4 Randomized Clinical TrialsView onlineSchließen
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Published in: JAMA Network Open
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Rick, Anne-Marie; Laurens, Matthew B.; Huang, Ying; Yu, Chenchen; Martin, Thomas C.S.; Rodriguez, Carina A.; Rostad, Christina A.; Maboa, Rebone M.; Baden, Lindsey R.; El Sahly, Hana M.; Grinsztejn, Beatriz; Gray, Glenda E.; Gay, Cynthia L.; Gilbert, Peter B.; Janes, Holly E.; Kublin, James G.; Huang, Yunda; Leav, Brett; Hirsch, Ian; Struyf, Frank; Dunkle, Lisa M.; Neuzil, Kathleen M.; Corey, Lawrence; Goepfert, Paul A.; [...]Risk of COVID-19 after natural infection or vaccinationView onlineSchließen
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Published in: eBioMedicine