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KOTSONIS, Peter; FREY, Armin; FRÖHLICH, Lothar G.; HOFMANN, Heinrich; REIF, Andreas; WINK, David A.; FEELISCH, Martin; SCHMIDT, Harald H.H.W.Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activityView onlineSchließen
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Published in: Biochemical Journal
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KOTSONIS, Peter; FREY, Armin; FRÖHLICH, Lothar G.; HOFMANN, Heinrich; REIF, Andreas; WINK, David A.; FEELISCH, Martin; SCHMIDT, Harald H. H. W.Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activityView onlineSchließen
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Published in: Biochemical Journal
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Reif, Andreas; Fröhlich, Lothar G.; Kotsonis, Peter; Frey, Armin; Bömmel, Heike M.; Schmidt, Harald H.H.W.; Wink, David A.; Pfleiderer, WolfgangTetrahydrobiopterin Inhibits Monomerization and Is Consumed during Catalysis in Neuronal NO SynthaseView onlineSchließen
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Published in: Journal of Biological Chemistry
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Mullins, Niamh [Author]; Kang, JooEun [Author]; Su, Mei-Hsin [Author]; Bryant, Richard [Author]; Treutlein, Jens [Author]; Dietl, Lydie [Author]; Schwarze, Cornelia E. [Author]; Dahmen, Norbert [Author]; Schott, Björn H. [Author]; Nöthen, Markus M. [Author]; Ripke, Stephan [Author]; Mobascher, Arian [Author]; Rujescu, Dan [Author]; Lieb, Klaus [Author]; Budde, Monika [Author]; Roepke, Stefan [Author]; Schmahl, Christian [Author]; Bohus, Martin [Author]; Rietschel, Marcella [Author]; Crivelli, Silvia [Author]; Dennis, Michelle F. [Author]; Harvey, Phillip D. [Author]; Carter, Bruce W. [Author]; Huffman, Jennifer E. [Author]; [...]Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk FactorsView onlineSchließen
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Published in: Biological psychiatry 91(3), 313-327 (2022). doi:10.1016/j.biopsych.2021.05.029
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Jacob, Christian P.; Romanos, Jasmin; Dempfle, Astrid; Heine, Monika; Windemuth-Kieselbach, Christine; Kruse, Anja; Reif, Andreas; Walitza, Susanne; Romanos, Marcel; Strobel, Alexander; Brocke, Burkhard; Schäfer, Helmut; Schmidtke, Armin; Böning, Jobst; Lesch, Klaus-PeterCo-morbidity of adult attention-deficit/hyperactivity disorder with focus on personality traits and related disorders in a tertiary referral centerView onlineSchließen
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Published in: European Archives of Psychiatry and Clinical Neuroscience
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Matter, Hans; Kumar, H. S. Arun; Fedorov, Roman; Frey, Armin; Kotsonis, Peter; Hartmann, Elisabeth; Fröhlich, Lothar G.; Reif, Andreas; Pfleiderer, Wolfgang; Scheurer, Peter; Ghosh, Dipak K.; Schlichting, Ilme; Schmidt, Harald H. H. W.Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide SynthasesView onlineSchließen
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Published in: Journal of Medicinal Chemistry
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Janova, Hana; Arinrad, Sahab; Balmuth, Evan; Mitjans, Marina; Hertel, Johannes; Habes, Mohamad; Bittner, Robert A.; Pan, Hong; Goebbels, Sandra; Begemann, Martin; Gerwig, Ulrike C.; Langner, Sönke; Werner, Hauke B.; Kittel-Schneider, Sarah; Homuth, Georg; Davatzikos, Christos; Völzke, Henry; West, Brian L.; Reif, Andreas; Grabe, Hans Jörgen; Boretius, Susann; Ehrenreich, Hannelore; Nave, Klaus-ArminMicroglia ablation alleviates myelin-associated catatonic signs in miceView onlineSchließen
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Published in: Journal of Clinical Investigation
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Bömmel, Heike M.; Reif, Andreas; Fröhlich, Lothar G.; Frey, Armin; Hofmann, Heinrich; Marecak, Dale M.; Groehn, Viola; Kotsonis, Peter; La, Mylinh; Köster, Sandra; Meinecke, Matthias; Bernhardt, Manfred; Weeger, Monika; Ghisla, Sandro; Prestwich, Glenn D.; Pfleiderer, Wolfgang; Schmidt, Harald H.H.W.Anti-pterins as Tools to Characterize the Function of Tetrahydrobiopterin in NO SynthaseView onlineSchließen
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Published in: Journal of Biological Chemistry
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Schubert, Klaus Oliver; Thalamuthu, Anbupalam; Amare, Azmeraw T.; Frank, Joseph; Streit, Fabian; Adl, Mazda; Akula, Nirmala; Akiyama, Kazufumi; Ardau, Raffaella; Arias, Bárbara; Aubry, Jean-Michel; Backlund, Lena; Bhattacharjee, Abesh Kumar; Bellivier, Frank; Benabarre, Antonio; Bengesser, Susanne; Biernacka, Joanna M.; Birner, Armin; Marie-Claire, Cynthia; Cearns, Micah; Cervantes, Pablo; Chen, Hsi-Chung; Chillotti, Caterina; Cichon, Sven; [...]Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patientsView onlineSchließen
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Published in: Translational Psychiatry
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Cearns, Micah; Amare, Azmeraw T.; Schubert, Klaus Oliver; Thalamuthu, Anbupalam; Frank, Joseph; Streit, Fabian; Adli, Mazda; Akula, Nirmala; Akiyama, Kazufumi; Ardau, Raffaella; Arias, Bárbara; Aubry, Jean-Michel; Backlund, Lena; Bhattacharjee, Abesh Kumar; Bellivier, Frank; Benabarre, Antonio; Bengesser, Susanne; Biernacka, Joanna M.; Birner, Armin; Brichant-Petitjean, Clara; Cervantes, Pablo; Chen, Hsi-Chung; Chillotti, Caterina; Cichon, Sven; [...]Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approachView onlineSchließen
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Published in: The British Journal of Psychiatry
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Cearns, Micah; Amare, Azmeraw T.; Schubert, Klaus Oliver; Thalamuthu, Anbupalam; Frank, Joseph; Streit, Fabian; Adli, Mazda; Akula, Nirmala; Akiyama, Kazufumi; Ardau, Raffaella; Arias, Bárbara; Aubry, JeanMichel; Backlund, Lena; Bhattacharjee, Abesh Kumar; Bellivier, Frank; Benabarre, Antonio; Bengesser, Susanne; Biernacka, Joanna M.; Birner, Armin; Brichant-Petitjean, Clara; Cervantes, Pablo; Chen, HsiChung; Chillotti, Caterina; Cichon, Sven; [...]Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach – CORRIGENDUMView onlineSchließen
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Published in: The British Journal of Psychiatry
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Schubert, Klaus Oliver; Thalamuthu, Anbupalam; Amare, Azmeraw T.; Frank, Joseph; Streit, Fabian; Adl, Mazda; Akula, Nirmala; Akiyama, Kazufumi; Ardau, Raffaella; Arias, Bárbara; Aubry, Jean-Michel; Backlund, Lena; Bhattacharjee, Abesh Kumar; Bellivier, Frank; Benabarre, Antonio; Bengesser, Susanne; Biernacka, Joanna M.; Birner, Armin; Marie-Claire, Cynthia; Cearns, Micah; Cervantes, Pablo; Chen, Hsi-Chung; Chillotti, Caterina; Cichon, Sven; [...]Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patientsView onlineSchließen
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Published in: Translational Psychiatry
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Le Clerc, Sigrid; Lombardi, Laura; Baune, Bernhard T.; Amare, Azmeraw T.; Schubert, Klaus Oliver; Hou, Liping; Clark, Scott R.; Papiol, Sergi; Cearns, Micah; Heilbronner, Urs; Degenhardt, Franziska; Tekola-Ayele, Fasil; Hsu, Yi-Hsiang; Shekhtman, Tatyana; Adli, Mazda; Akula, Nirmala; Akiyama, Kazufumi; Ardau, Raffaella; Arias, Bárbara; Aubry, Jean-Michel; Backlund, Lena; Bhattacharjee, Abesh Kumar; Bellivier, Frank; Benabarre, Antonio; [...]HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disordersView onlineSchließen
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Published in: Scientific Reports
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Reinbold, Céline S.; Forstner, Andreas J.; Hecker, Julian; Fullerton, Janice M.; Hoffmann, Per; Hou, Liping; Heilbronner, Urs; Degenhardt, Franziska; Adli, Mazda; Akiyama, Kazufumi; Akula, Nirmala; Ardau, Raffaella; Arias, Bárbara; Backlund, Lena; Benabarre, Antonio; Bengesser, Susanne; Bhattacharjee, Abesh K.; Biernacka, Joanna M.; Birner, Armin; Marie-Claire, Cynthia; Cervantes, Pablo; Chen, Guo-Bo; Chen, Hsi-Chung; Chillotti, Caterina; [...]Analysis of the Influence of microRNAs in Lithium Response in Bipolar DisorderView onlineSchließen
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Published in: Frontiers in Psychiatry
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Amare, Azmeraw T.; Schubert, Klaus Oliver; Hou, Liping; Clark, Scott R.; Papiol, Sergi; Heilbronner, Urs; Degenhardt, Franziska; Tekola-Ayele, Fasil; Hsu, Yi-Hsiang; Shekhtman, Tatyana; Adli, Mazda; Akula, Nirmala; Akiyama, Kazufumi; Ardau, Raffaella; Arias, Bárbara; Aubry, Jean-Michel; Backlund, Lena; Bhattacharjee, Abesh Kumar; Bellivier, Frank; Benabarre, Antonio; Bengesser, Susanne; Biernacka, Joanna M.; Birner, Armin; Brichant-Petitjean, Clara; [...]Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder : A Genome-Wide Association Study : A Genome-Wide Association StudyView onlineSchließen
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Published in: JAMA Psychiatry
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Amare, Azmeraw T.; Thalamuthu, Anbupalam; Schubert, Klaus Oliver; Fullerton, Janice M.; Ahmed, Muktar; Hartmann, Simon; Papiol, Sergi; Heilbronner, Urs; Degenhardt, Franziska; Tekola-Ayele, Fasil; Hou, Liping; Hsu, Yi-Hsiang; Shekhtman, Tatyana; Adli, Mazda; Akula, Nirmala; Akiyama, Kazufumi; Ardau, Raffaella; Arias, Bárbara; Aubry, Jean-Michel; Hasler, Roland; Richard-Lepouriel, Hélène; Perroud, Nader; Backlund, Lena; Bhattacharjee, Abesh Kumar; [...]Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorderView onlineSchließen
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Published in: Molecular Psychiatry
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Kalman, Janos L; Papiol, Sergi; Forstner, Andreas J; Heilbronner, Urs; Degenhardt, Franziska; Strohmaier, Jana; Adli, Mazda; Adorjan, Kristina; Akula, Nirmala; Alda, Martin; Anderson‐Schmidt, Heike; Andlauer, Till FM; Anghelescu, Ion‐George; Ardau, Raffaella; Arias, Bárbara; Arolt, Volker; Aubry, Jean‐Michel; Backlund, Lena; Bartholdi, Kim; Bauer, Michael; Baune, Bernhard T; Becker, Thomas; Bellivier, Frank; Benabarre, Antonio; [...]Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric studyView onlineSchließen
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Published in: Bipolar Disorders
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Hou, Liping; Bergen, Sarah E.; Akula, Nirmala; Song, Jie; Hultman, Christina M.; Landén, Mikael; Adli, Mazda; Alda, Martin; Ardau, Raffaella; Arias, Bárbara; Aubry, Jean-Michel; Backlund, Lena; Badner, Judith A.; Barrett, Thomas B.; Bauer, Michael; Baune, Bernhard T.; Bellivier, Frank; Benabarre, Antonio; Bengesser, Susanne; Berrettini, Wade H.; Bhattacharjee, Abesh Kumar; Biernacka, Joanna M.; Birner, Armin; Bloss, Cinnamon S.; [...]Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorderView onlineSchließen
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Published in: Human Molecular Genetics
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Amare, Azmeraw T.; Schubert, Klaus Oliver; Hou, Liping; Clark, Scott R.; Papiol, Sergi; Cearns, Micah; Heilbronner, Urs; Degenhardt, Franziska; Tekola-Ayele, Fasil; Hsu, Yi-Hsiang; Shekhtman, Tatyana; Adli, Mazda; Akula, Nirmala; Akiyama, Kazufumi; Ardau, Raffaella; Arias, Bárbara; Aubry, Jean-Michel; Backlund, Lena; Bhattacharjee, Abesh Kumar; Bellivier, Frank; Benabarre, Antonio; Bengesser, Susanne; Biernacka, Joanna M.; Birner, Armin; [...]Association of polygenic score for major depression with response to lithium in patients with bipolar disorderView onlineSchließen
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Published in: Molecular Psychiatry
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Mullins, Niamh; Forstner, Andreas J.; O’Connell, Kevin S.; Coombes, Brandon; Coleman, Jonathan R. I.; Qiao, Zhen; Als, Thomas D.; Bigdeli, Tim B.; Børte, Sigrid; Bryois, Julien; Charney, Alexander W.; Drange, Ole Kristian; Gandal, Michael J.; Hagenaars, Saskia P.; Ikeda, Masashi; Kamitaki, Nolan; Kim, Minsoo; Krebs, Kristi; Panagiotaropoulou, Georgia; Schilder, Brian M.; Sloofman, Laura G.; Steinberg, Stacy; Trubetskoy, Vassily; Winsvold, Bendik S.; [...]Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biologyView onlineSchließen
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Published in: Nature Genetics