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Avitabile, Marianna [Author]

Characterization of Hypoxia Inducible Factor HIF-1α function and identification of its targets to improve therapeutic intervention in Neuroblastoma malignancy

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[Erscheinungsort nicht ermittelbar]: [Verlag nicht ermittelbar], 2017
Cimmino, Flora; Pezone, Lucia; Avitabile, Marianna; Acierno, Giovanni; Andolfo, Immacolata; Capasso, Mario; Iolascon, Achille

Inhibition of hypoxia inducible factors combined with all-trans retinoic acid treatment enhances glial transdifferentiation of neuroblastoma cells

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Springer Science and Business Media LLC, 2015

Published in: Scientific Reports, 5 (2015) 1
Formicola, Daniela; Lasorsa, Vito Alessandro; Cantalupo, Sueva; Testori, Alessandro; Cardinale, Antonella; Avitabile, Marianna; Diskin, Sharon; Iolascon, Achille; Capasso, Mario

CFDP1 is a neuroblastoma susceptibility gene that regulates transcription factors of the noradrenergic cell identity

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Elsevier BV, 2023

Published in: Human Genetics and Genomics Advances, 4 (2023) 1, Seite 100158
Cimmino, Flora; Avitabile, Marianna; Lasorsa, Vito Alessandro; Pezone, Lucia; Cardinale, Antonella; Montella, Annalaura; Cantalupo, Sueva; Iolascon, Achille; Capasso, Mario

Functional characterization of full-length BARD1 strengthens its role as a tumor suppressor in neuroblastoma

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Ivyspring International Publisher, 2020

Published in: Journal of Cancer, 11 (2020) 6, Seite 1495-1504
Capasso, Mario; Aievola, Vincenzo; Lasorsa, Vito Alessandro; Montella, Annalaura; Bonfiglio, Ferdinando; Avitabile, Marianna; Maiorino, Teresa; Tirelli, Matilde; D'Alterio, Giuseppe; Fischer, Matthias; Westermann, Frank; Iolascon, Achille

Abstract 2850: Noncoding regulatory mutations as driving event for the oncogenic core regulatory circuitries of neuroblastoma

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American Association for Cancer Research (AACR), 2024

Published in: Cancer Research, 84 (2024) 6_Supplement, Seite 2850-2850
Avitabile, Marianna; Bonfiglio, Ferdinando; Aievola, Vincenzo; Cantalupo, Sueva; Maiorino, Teresa; Lasorsa, Vito Alessandro; Domenicotti, Cinzia; Marengo, Barbara; Zbyněk, Heger; Vojtěch, Adam; Iolascon, Achille; Capasso, Mario

Single-cell transcriptomics of neuroblastoma identifies chemoresistance-associated genes and pathways

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Elsevier BV, 2022

Published in: Computational and Structural Biotechnology Journal, 20 (2022), Seite 4437-4445
Capasso, Mario; Lasorsa, Vito Alessandro; Cimmino, Flora; Avitabile, Marianna; Cantalupo, Sueva; Montella, Annalaura; De Angelis, Biagio; Morini, Martina; de Torres, Carmen; Castellano, Aurora; Locatelli, Franco; Iolascon, Achille

Transcription Factors Involved in Tumorigenesis Are Over-Represented in Mutated Active DNA-Binding Sites in Neuroblastoma

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American Association for Cancer Research (AACR), 2020

Published in: Cancer Research, 80 (2020) 3, Seite 382-393
Cimmino, Flora; Avitabile, Marianna; Lasorsa, Vito Alessandro; Montella, Annalaura; Pezone, Lucia; Cantalupo, Sueva; Visconte, Feliciano; Corrias, Maria Valeria; Iolascon, Achille; Capasso, Mario

HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia

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Springer Science and Business Media LLC, 2019

Published in: BMC Medical Genetics, 20 (2019) 1
Russo, Roberta; Cimmino, Flora; Pezone, Lucia; Manna, Francesco; Avitabile, Marianna; Langella, Concetta; Koster, Jan; Casale, Fiorina; Raia, Maddalena; Viola, Giampietro; Fischer, Matthias; Iolascon, Achille; Capasso, Mario

Kinome expression profiling of human neuroblastoma tumors identifies potential drug targets for ultra high-risk patients

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Oxford University Press (OUP), 2017

Published in: Carcinogenesis, 38 (2017) 10, Seite 1011-1020
Cimmino, Flora; Pezone, Lucia; Avitabile, Marianna; Persano, Luca; Vitale, Monica; Sassi, Mauro; Bresolin, Silvia; Serafin, Valentina; Zambrano, Nicola; Scaloni, Andrea; Basso, Giuseppe; Iolascon, Achille; Capasso, Mario

Proteomic Alterations in Response to Hypoxia Inducible Factor 2α in Normoxic Neuroblastoma Cells

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American Chemical Society (ACS), 2016

Published in: Journal of Proteome Research, 15 (2016) 10, Seite 3643-3655
Cimmino, Flora; Montella, Annalaura; Tirelli, Matilde; Avitabile, Marianna; Lasorsa, Vito Alessandro; Visconte, Feliciano; Cantalupo, Sueva; Maiorino, Teresa; De Angelis, Biagio; Morini, Martina; Castellano, Aurora; Locatelli, Franco; Capasso, Mario; Iolascon, Achille

FGFR1 is a potential therapeutic target in neuroblastoma

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Springer Science and Business Media LLC, 2022

Published in: Cancer Cell International, 22 (2022) 1
Avitabile, Marianna; Lasorsa, Vito Alessandro; Cantalupo, Sueva; Cardinale, Antonella; Cimmino, Flora; Montella, Annalaura; Capasso, Dalila; Haupt, Riccardo; Amoroso, Loredana; Garaventa, Alberto; Quattrone, Alessandro; Corrias, Maria Valeria; Iolascon, Achille; Capasso, Mario

Association of PARP1 polymorphisms with response to chemotherapy in patients with high‐risk neuroblastoma

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Wiley, 2020

Published in: Journal of Cellular and Molecular Medicine, 24 (2020) 7, Seite 4072-4081
Reibaldi, Michele; Avitabile, Teresio; Bandello, Francesco; Longo, Antonio; Bonfiglio, Vincenza; Russo, Andrea; Castellino, Niccolò; Rejdak, Robert; Nowomiejska, Katarzyna; Toro, Mario; Furino, Claudio; Cillino, Salvatore; Fiore, Tito; Cagini, Carlo; Grassi, Patrizia; Musumeci, Rosario; Cocuzza, Clementina Elvezia; Martinelli, Marianna; Fallico, Matteo

The Effectiveness of 0.6% Povidone Iodine Eye Drops in Reducing the Conjunctival Bacterial Load and Needle Contamination in Patients Undergoing Anti-VEGF Intravitreal Injection: A Prospective, Randomized Study

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MDPI AG, 2019

Published in: Journal of Clinical Medicine, 8 (2019) 7, Seite 1031
Testori, Alessandro; Lasorsa, Vito A.; Cimmino, Flora; Cantalupo, Sueva; Cardinale, Antonella; Avitabile, Marianna; Limongelli, Giuseppe; Russo, Maria Giovanna; Diskin, Sharon; Maris, John; Devoto, Marcella; Keavney, Bernard; Cordell, Heather J.; Iolascon, Achille; Capasso, Mario

Exploring Shared Susceptibility between Two Neural Crest Cells Originating Conditions: Neuroblastoma and Congenital Heart Disease

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MDPI AG, 2019

Published in: Genes, 10 (2019) 9, Seite 663
Cimmino, Flora; Avitabile, Marianna; Diskin, Sharon J.; Vaksman, Zalman; Pignataro, Piero; Formicola, Daniela; Cardinale, Antonella; Testori, Alessandro; Koster, Jan; de Torres, Carmen; Devoto, Marcella; Maris, John M.; Iolascon, Achille; Capasso, Mario

Fine mapping of 2q35 high‐risk neuroblastoma locus reveals independent functional risk variants and suggests full‐length BARD1 as tumor‐suppressor

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Wiley, 2018

Published in: International Journal of Cancer, 143 (2018) 11, Seite 2828-2837
Cardinale, Antonella; Cantalupo, Sueva; Lasorsa, Vito Alessandro; Montella, Annalaura; Cimmino, Flora; Succoio, Mariangela; Vermeulen, Michiel; Baltissen, Marijke P; Esposito, Matteo; Avitabile, Marianna; Formicola, Daniela; Testori, Alessandro; Bonfiglio, Ferdinando; Ghiorzo, Paola; Scalvenzi, Massimiliano; Ayala, Fabrizio; Zambrano, Nicola; Iles, Mark M; Xu, Mai; Law, Matthew H; Brown, Kevin M; Iolascon, Achille; Capasso, Mario

Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation ofOBFC1

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Oxford University Press (OUP), 2022

Published in: Human Molecular Genetics, 31 (2022) 6, Seite 863-874
Avitabile, Marianna; Succoio, Mariangela; Testori, Alessandro; Cardinale, Antonella; Vaksman, Zalman; Lasorsa, Vito Alessandro; Cantalupo, Sueva; Esposito, Matteo; Cimmino, Flora; Montella, Annalaura; Formicola, Daniela; Koster, Jan; Andreotti, Virginia; Ghiorzo, Paola; Romano, Maria Fiammetta; Staibano, Stefania; Scalvenzi, Massimiliano; Ayala, Fabrizio; Hakonarson, Hakon; Corrias, Maria Valeria; Devoto, Marcella; Law, Matthew H; Iles, Mark M; Brown, Kevin; [...]

Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene

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Oxford University Press (OUP), 2020

Published in: Carcinogenesis, 41 (2020) 3, Seite 284-295
Sidarovich, Viktoryia; De Mariano, Marilena; Aveic, Sanja; Pancher, Michael; Adami, Valentina; Gatto, Pamela; Pizzini, Silvia; Pasini, Luigi; Croce, Michela; Parodi, Federica; Cimmino, Flora; Avitabile, Marianna; Emionite, Laura; Cilli, Michele; Ferrini, Silvano; Pagano, Aldo; Capasso, Mario; Quattrone, Alessandro; Tonini, Gian Paolo; Longo, Luca

A High-Content Screening of Anticancer Compounds Suggests the Multiple Tyrosine Kinase Inhibitor Ponatinib for Repurposing in Neuroblastoma Therapy

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American Association for Cancer Research (AACR), 2018

Published in: Molecular Cancer Therapeutics, 17 (2018) 7, Seite 1405-1415
Capasso, Mario; Brignole, Chiara; Lasorsa, Vito A.; Bensa, Veronica; Cantalupo, Sueva; Sebastiani, Enrico; Quattrone, Alessandro; Ciampi, Eleonora; Avitabile, Marianna; Sementa, Angela R.; Mazzocco, Katia; Cafferata, Barbara; Gaggero, Gabriele; Vellone, Valerio G.; Cilli, Michele; Calarco, Enzo; Giusto, Elena; Perri, Patrizia; Aveic, Sanja; Fruci, Doriana; Tondo, Annalisa; Luksch, Roberto; Mura, Rossella; Rabusin, Marco; [...]

From the identification of actionable molecular targets to the generation of faithful neuroblastoma patient-derived preclinical models

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Springer Science and Business Media LLC, 2024

Published in: Journal of Translational Medicine, 22 (2024) 1
Panozzo, Giacomo; Cicinelli, Maria V.; Dalla Mura, Giulia; Giannarelli, Diana; Vadalà, Maria; Bonfiglio, Vincenza; Bellisario, Giovanni; Bandello, Francesco; Angelini, Edoardo; Airaghi, Pietro; Avitabile, Teresio; Beccastrini, Andrea; Benedetti, Giorgia; Bertuzzi, Federico; Bonfiglio, Vincenza Maria Elena; Boscia, Francesco; Carnevali, Adriano; Carosielli, Marianna; Cereda, Matteo Giuseppe; Contardi, Cecilia; Coppola, Michele; Costagliola, Ciro; Cristofolini, Riccardo; Cucciniello, Pasquale; [...]

Enhancing Diabetic Macular Edema Treatment Outcomes: Exploring the ESASO Classification and Structural OCT Biomarkers

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Springer Science and Business Media LLC, 2024

Published in: Ophthalmology and Therapy, 13 (2024) 5, Seite 1383-1398

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