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  2. Brummer, Christina [Author]; Pukrop, Tobias [Author]; Wiskemann, Joachim [Author]; Bruss, Christina [Author]; Ugele, Ines [Author]; Renner, Kathrin [Author]

    Can exercise enhance the efficacy of checkpoint inhibition by modulating anti-tumor immunity?

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    2023

    Published in: Cancers ; 15(2023), 18, Artikel-ID 4668, Seite 1-24

  3. Renner, Kathrin [Author]; Bruss, Christina [Author]; Schnell, Annette [Author]; Lang, Sven Arke [Author]; Kreutz, Marina [Author]

    Restricting glycolysis preserves T cell effector functions and augments checkpoint therapy

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    Maryland Heights, MO: Cell Press, 2019

    Published in: Cell reports ; 29, 1 (2019), 135-150.e9

  6. Bruss, Christina; Albert, Veruschka; Seitz, Stephan; Blaimer, Stephanie; Kellner, Kerstin; Pohl, Fabian; Ortmann, Olaf; Brockhoff, Gero; Wege, Anja K.

    Neoadjuvant radiotherapy in ER+, HER2+, and triple-negative -specific breast cancer based humanized tumor mice enhances anti-PD-L1 treatment efficacy

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    Frontiers Media SA, 2024

    Published in: Frontiers in Immunology, 15 (2024)

  9. Decking, Sonja-Maria; Bruss, Christina; Babl, Nathalie; Bittner, Sebastian; Klobuch, Sebastian; Thomas, Simone; Feuerer, Markus; Hoffmann, Petra; Dettmer, Katja; Oefner, Peter J.; Renner, Kathrin; Kreutz, Marina

    LDHB Overexpression Can Partially Overcome T Cell Inhibition by Lactic Acid

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    MDPI AG, 2022

    Published in: International Journal of Molecular Sciences, 23 (2022) 11, Seite 5970

  10. Ugele, Ines; Cárdenas-Conejo, Zugey; Hammon, Kathrin; Wehrstein, Monika; Bruss, Christina; Peter, Katrin; Singer, Katrin; Gottfried, Eva; Boesch, Jakob; Oefner, Peter; Dettmer, Katja; Renner, Kathrin; Kreutz, Marina

    D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells

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    MDPI AG, 2019

    Published in: International Journal of Molecular Sciences, 20 (2019) 3, Seite 742

  11. Renner, Kathrin; Geiselhöringer, Anna‐Lena; Fante, Matthias; Bruss, Christina; Färber, Stephanie; Schönhammer, Gabriele; Peter, Katrin; Singer, Katrin; Andreesen, Reinhard; Hoffmann, Petra; Oefner, Peter; Herr, Wolfgang; Kreutz, Marina

    Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2‐deoxy‐glucose affects effector functions

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    Wiley, 2015

    Published in: European Journal of Immunology, 45 (2015) 9, Seite 2504-2516

  12. Renner, Kathrin; Seilbeck, Anton; Kauer, Nathalie; Ugele, Ines; Siska, Peter J.; Brummer, Christina; Bruss, Christina; Decking, Sonja-Maria; Fante, Matthias; Schmidt, Astrid; Hammon, Kathrin; Singer, Katrin; Klobuch, Sebastian; Thomas, Simone; Gottfried, Eva; Peter, Katrin; Kreutz, Marina

    Combined Metabolic Targeting With Metformin and the NSAIDs Diflunisal and Diclofenac Induces Apoptosis in Acute Myeloid Leukemia Cells

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    Frontiers Media SA, 2018

    Published in: Frontiers in Pharmacology, 9 (2018)

  13. Schoeppe, Robert; Babl, Nathalie; Decking, Sonja-Maria; Schönhammer, Gabriele; Siegmund, Andreas; Bruss, Christina; Dettmer, Katja; Oefner, Peter J.; Frick, Linus; Weigert, Anna; Jantsch, Jonathan; Herr, Wolfgang; Rehli, Michael; Renner, Kathrin; Kreutz, Marina

    Glutamine synthetase expression rescues human dendritic cell survival in a glutamine-deprived environment

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    Frontiers Media SA, 2023

    Published in: Frontiers in Oncology, 13 (2023)

  14. Matos, Carina; Renner, Kathrin; Peuker, Alice; Schoenhammer, Gabriele; Schreiber, Laura; Bruss, Christina; Eder, Ruediger; Bruns, Heiko; Flamann, Cindy; Hoffmann, Petra; Gebhard, Claudia; Herr, Wolfgang; Rehli, Michael; Peter, Katrin; Kreutz, Marina

    Physiological levels of 25‐hydroxyvitamin D3 induce a suppressive CD4+ T cell phenotype not reflected in the epigenetic landscape

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    Wiley, 2022

    Published in: Scandinavian Journal of Immunology, 95 (2022) 5

  15. Babl, Nathalie; Decking, Sonja-Maria; Voll, Florian; Althammer, Michael; Sala-Hojman, Ada; Ferretti, Roberta; Korf, Clarissa; Schmidl, Christian; Schmidleithner, Lisa; Nerb, Benedikt; Matos, Carina; Koehl, Gudrun E; Siska, Peter; Bruss, Christina; Kellermeier, Fabian; Dettmer, Katja; Oefner, Peter J; Wichland, Marvin; Ugele, Ines; Bohr, Christopher; Herr, Wolfgang; Ramaswamy, Shivapriya; Heinrich, Timo; Herhaus, Christian; [...]

    MCT4 blockade increases the efficacy of immune checkpoint blockade

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    BMJ, 2023

    Published in: Journal for ImmunoTherapy of Cancer, 11 (2023) 10, Seite e007349

  16. Ždralević, Maša; Brand, Almut; Di Ianni, Lorenza; Dettmer, Katja; Reinders, Jörg; Singer, Katrin; Peter, Katrin; Schnell, Annette; Bruss, Christina; Decking, Sonja-Maria; Koehl, Gudrun; Felipe-Abrio, Blanca; Durivault, Jérôme; Bayer, Pascale; Evangelista, Marie; O'Brien, Thomas; Oefner, Peter J.; Renner, Kathrin; Pouysségur, Jacques; Kreutz, Marina

    Double genetic disruption of lactate dehydrogenases A and B is required to ablate the “Warburg effect” restricting tumor growth to oxidative metabolism

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    Elsevier BV, 2018

    Published in: Journal of Biological Chemistry, 293 (2018) 41, Seite 15947-15961

  17. Tu, Zhidong; Keller, Mark P.; Zhang, Chunsheng; Rabaglia, Mary E.; Greenawalt, Danielle M.; Yang, Xia; Wang, I-Ming; Dai, Hongyue; Bruss, Matthew D.; Lum, Pek Y.; Zhou, Yun-Ping; Kemp, Daniel M.; Kendziorski, Christina; Yandell, Brian S.; Attie, Alan D.; Schadt, Eric E.; Zhu, Jun

    Integrative Analysis of a Cross-Loci Regulation Network Identifies App as a Gene Regulating Insulin Secretion from Pancreatic Islets

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    Public Library of Science (PLoS), 2012

    Published in: PLoS Genetics, 8 (2012) 12, Seite e1003107

  18. Brand, Almut; Singer, Katrin; Koehl, Gudrun E.; Kolitzus, Marlene; Schoenhammer, Gabriele; Thiel, Annette; Matos, Carina; Bruss, Christina; Klobuch, Sebastian; Peter, Katrin; Kastenberger, Michael; Bogdan, Christian; Schleicher, Ulrike; Mackensen, Andreas; Ullrich, Evelyn; Fichtner-Feigl, Stefan; Kesselring, Rebecca; Mack, Matthias; Ritter, Uwe; Schmid, Maximilian; Blank, Christian; Dettmer, Katja; Oefner, Peter J.; Hoffmann, Petra; [...]

    LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

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    Elsevier BV, 2016

    Published in: Cell Metabolism, 24 (2016) 5, Seite 657-671

  19. Renner, Kathrin; Bruss, Christina; Schnell, Annette; Koehl, Gudrun; Becker, Holger M.; Fante, Matthias; Menevse, Ayse-Nur; Kauer, Nathalie; Blazquez, Raquel; Hacker, Lisa; Decking, Sonja-Maria; Bohn, Toszka; Faerber, Stephanie; Evert, Katja; Aigle, Lisa; Amslinger, Sabine; Landa, Maria; Krijgsman, Oscar; Rozeman, Elisa A.; Brummer, Christina; Siska, Peter J.; Singer, Katrin; Pektor, Stefanie; Miederer, Matthias; [...]

    Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy

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    Elsevier BV, 2019

    Published in: Cell Reports, 29 (2019) 1, Seite 135-150.e9

  20. Siska, Peter J.; Decking, Sonja-Maria; Babl, Nathalie; Matos, Carina; Bruss, Christina; Singer, Katrin; Klitzke, Jana; Schön, Marian; Simeth, Jakob; Köstler, Josef; Siegmund, Heiko; Ugele, Ines; Paulus, Michael; Dietl, Alexander; Kolodova, Kristina; Steines, Louisa; Freitag, Katharina; Peuker, Alice; Schönhammer, Gabriele; Raithel, Johanna; Graf, Bernhard; Geismann, Florian; Lubnow, Matthias; Mack, Matthias; [...]

    Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone

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    American Society for Clinical Investigation, 2021

    Published in: Journal of Clinical Investigation, 131 (2021) 22