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Boutros, Michael [Author]; Buchhalter, Ivo [Author] ; Deutsches Krebsforschungszentrum

"Deutsches Netzwerk für Bioinformatik-Infrastruktur - de.NBI" Heidelberg Center for Human Bioinformatics (HD-HuB) : Schlussbericht für das Projekt

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Heidelberg: Deutsches Krebsforschungszentrum (DKFZ), 30.06.2021
Feuerbach, Lars [Author]; Sieverling, Lina Katharine [Author]; Deeg, Katharina [Author]; Hutter, Barbara [Author]; Buchhalter, Ivo [Author]; Mughal, Sadaf Shabbir [Author]; Chudasama, Priya [Author]; Glimm, Hanno [Author]; Scholl, Claudia [Author]; Lichter, Peter [Author]; Fröhling, Stefan [Author]; Pfister, Stefan [Author]; Jones, David T. W. [Author]; Rippe, Karsten [Author]; Brors, Benedikt [Author]

TelomereHunter : in silico estimation of telomere content and composition from cancer genomes

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Heidelberg: Universitätsbibliothek Heidelberg, 06 Aug. 2019 ; London: BioMed Central, 06 Aug. 2019
Gießler, Klara Monika [Author]; Kleinheinz, Kortine [Author]; Hübschmann, Daniel [Author]; Balasubramanian, Gnana Prakash [Author]; Dubash, Taronish Dorab [Author]; Dieter, Sebastian M. [Author]; Siegl, Christine [Author]; Herbst, Friederike [Author]; Weber, Sarah [Author]; Hoffmann, Christopher M. [Author]; Fronza, Raffaele [Author]; Buchhalter, Ivo [Author]; Paramasivam, Nagarajan [Author]; Eils, Roland [Author]; Schmidt, Manfred [Author]; Kalle, Christof von [Author]; Schneider, Martin [Author]; Ulrich, Alexis [Author]; Scholl, Claudia [Author]; Fröhling, Stefan [Author]; Weichert, Wilko [Author]; Brors, Benedikt [Author]; Schlesner, Matthias [Author]; Ball, Claudia R. [Author];

Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer

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2017

Published in: Journal of experimental medicine ; 214(2017), 7, Seite 2073-2088
Sturm, Dominik [Author]; Orr, Brent A. [Author]; Toprak, Umut H. [Author]; Hovestadt, Volker [Author]; Jones, David T.W. [Author]; Capper, David [Author]; Sill, Martin [Author]; Buchhalter, Ivo [Author]; Northcott, Paul A. [Author]; Leis, Irina [Author]; Ryzhova, Marina [Author]; Koelsche, Christian [Author]; Pfaff, Elke [Author]; Allen, Sariah J. [Author]; Balasubramanian, Gnanaprakash [Author]; Worst, Barbara C. [Author]; Pajtler, Kristian W. [Author]; Brabetz, Sebastian [Author]; Johann, Pascal-David [Author]; Sahm, Felix [Author]; Reimand, Jüri [Author]; Mackay, Alan [Author]; Carvalho, Diana M. [Author]; Remke, Marc [Author]; [...]

New brain tumor entities emerge from molecular classification of CNS-PNETs

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Augsburg University Publication Server (OPUS), 2016
Koşaloğlu, Zeynep; Zörnig, Inka; Halama, Niels; Kaiser, Iris; Buchhalter, Ivo; Grabe, Niels; Eils, Roland; Schlesner, Matthias; Califano, Andrea; Jäger, Dirk

Identification of immunotherapeutic targets by genomic profiling of rectal NET metastases

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Informa UK Limited, 2016

Published in: OncoImmunology, 5 (2016) 11, Seite e1213931
Buchhalter, Ivo; Rempel, Eugen; Endris, Volker; Allgäuer, Michael; Neumann, Olaf; Volckmar, Anna‐Lena; Kirchner, Martina; Leichsenring, Jonas; Lier, Amelie; von Winterfeld, Moritz; Penzel, Roland; Christopoulos, Petros; Thomas, Michael; Fröhling, Stefan; Schirmacher, Peter; Budczies, Jan; Stenzinger, Albrecht

Size matters: Dissecting key parameters for panel‐based tumor mutational burden analysis

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Wiley, 2019

Published in: International Journal of Cancer, 144 (2019) 4, Seite 848-858
Feuerbach, Lars; Sieverling, Lina; Deeg, Katharina I.; Ginsbach, Philip; Hutter, Barbara; Buchhalter, Ivo; Northcott, Paul A.; Mughal, Sadaf S.; Chudasama, Priya; Glimm, Hanno; Scholl, Claudia; Lichter, Peter; Fröhling, Stefan; Pfister, Stefan M.; Jones, David T. W.; Rippe, Karsten; Brors, Benedikt

TelomereHunter – in silico estimation of telomere content and composition from cancer genomes

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Springer Science and Business Media LLC, 2019

Published in: BMC Bioinformatics, 20 (2019) 1
Endris, Volker; Buchhalter, Ivo; Allgäuer, Michael; Kirchner, Martina; Leichsenring, Jonas; Volckmar, Anna-Lena; Stögbauer, Fabian; Horak, Peter; Kreutzfeld, Simon; Glimm, Hanno; Froehling, Stefan; Neumann, Olaf; Penzel, Roland; Schirmacher, Peter; Stenzinger, Albrecht

Determination of tumor mutational burden using FFPE material: Content and performance comparison of different gene panels

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American Society of Clinical Oncology (ASCO), 2018

Published in: Journal of Clinical Oncology, 36 (2018) 15_suppl, Seite e15010-e15010
Johann, Pascal D.; Erkek, Serap; Zapatka, Marc; Kerl, Kornelius; Buchhalter, Ivo; Hovestadt, Volker; Korshunov, Andrey; Marina, Rhyzova; Jones, David T.W.; Northcott, Paul A.; Frühwald, Michael; Gajjar, Amar; Hasselblatt, Martin; Pfister, Stefan M.; Kool, Marcel

PTPS-11ATYPICAL TERATOID/RHABDOID TUMOUR IS AN EPIGENETICALLY HETEROGENEOUS DISEASE CHARACTERIZED BY SUBGROUP SPECIFIC SUPER-ENHANCERS

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Oxford University Press (OUP), 2015

Published in: Neuro-Oncology, 17 (2015) suppl 5, Seite v181.2-v181
Mudduluru, Giridhar; Abba, Mohammed; Batliner, Jasmin; Patil, Nitin; Lunavat, Taral R.; Scharp, Maike; Leupold, Jörg; Oleksiuk, Olga; Buchhalter, Ivo; Thiele, Wilko; Rothley, Melanie; Benner, Axel; Sleeman, Jonathan; Allgayer, Heike

Abstract 1443: A systematic approach to the metastatically relevant microRNA landscape

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American Association for Cancer Research (AACR), 2014

Published in: Cancer Research, 74 (2014) 19_Supplement, Seite 1443-1443
Whalley, Justin P.; Buchhalter, Ivo; Rheinbay, Esther; Raine, Keiran M.; Stobbe, Miranda D.; Kleinheinz, Kortine; Werner, Johannes; Beltran, Sergi; Gut, Marta; Hübschmann, Daniel; Hutter, Barbara; Livitz, Dimitri; Perry, Marc D.; Rosenberg, Mara; Saksena, Gordon; Trotta, Jean-Rémi; Eils, Roland; Gerhard, Daniela S.; Campbell, Peter J.; Schlesner, Matthias; Gut, Ivo G.

Framework for quality assessment of whole genome cancer sequences

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Springer Science and Business Media LLC, 2020

Published in: Nature Communications, 11 (2020) 1
Endris, Volker; Buchhalter, Ivo; Allgäuer, Michael; Rempel, Eugen; Lier, Amelie; Volckmar, Anna‐Lena; Kirchner, Martina; von Winterfeld, Moritz; Leichsenring, Jonas; Neumann, Olaf; Penzel, Roland; Weichert, Wilko; Glimm, Hanno; Fröhling, Stefan; Winter, Hauke; Herth, Felix; Thomas, Michael; Schirmacher, Peter; Budczies, Jan; Stenzinger, Albrecht

Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels

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Wiley, 2019

Published in: International Journal of Cancer, 144 (2019) 9, Seite 2303-2312
Christopoulos, Petros; Endris, Volker; Bozorgmehr, Farastuk; Elsayed, Mei; Kirchner, Martina; Ristau, Jonas; Buchhalter, Ivo; Penzel, Roland; Herth, Felix J.; Heussel, Claus P.; Eichhorn, Martin; Muley, Thomas; Meister, Michael; Fischer, Jürgen R.; Rieken, Stefan; Warth, Arne; Bischoff, Helge; Schirmacher, Peter; Stenzinger, Albrecht; Thomas, Michael

EML4‐ALK fusion variant V3 is a high‐risk feature conferring accelerated metastatic spread, early treatment failure and worse overall survival in ALK+ non‐small cell lung cancer

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Wiley, 2018

Published in: International Journal of Cancer, 142 (2018) 12, Seite 2589-2598
Iorgulescu, J. Bryan; Van Ziffle, Jessica; Stevers, Meredith; Grenert, James P.; Bastian, Boris C.; Chavez, Lukas; Stichel, Damian; Buchhalter, Ivo; Samuel, David; Nicolaides, Theodore; Banerjee, Anuradha; Mueller, Sabine; Gupta, Nalin; Tihan, Tarik; Bollen, Andrew W.; Northcott, Paul A.; Kool, Marcel; Pfister, Stefan; Korshunov, Andrey; Perry, Arie; Solomon, David A.

Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation

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Springer Science and Business Media LLC, 2018

Published in: Acta Neuropathologica, 135 (2018) 4, Seite 635-638
Giessler, Klara M.; Kleinheinz, Kortine; Huebschmann, Daniel; Balasubramanian, Gnana Prakash; Dubash, Taronish D.; Dieter, Sebastian M.; Siegl, Christine; Herbst, Friederike; Weber, Sarah; Hoffmann, Christopher M.; Fronza, Raffaele; Buchhalter, Ivo; Paramasivam, Nagarajan; Eils, Roland; Schmidt, Manfred; von Kalle, Christof; Schneider, Martin; Ulrich, Alexis; Scholl, Claudia; Fröhling, Stefan; Weichert, Wilko; Brors, Benedikt; Schlesner, Matthias; Ball, Claudia R.;

Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer

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Rockefeller University Press, 2017

Published in: Journal of Experimental Medicine, 214 (2017) 7, Seite 2073-2088
Sahm, Felix; Toprak, Umut H.; Hübschmann, Daniel; Kleinheinz, Kortine; Buchhalter, Ivo; Sill, Martin; Stichel, Damian; Schick, Matthias; Bewerunge-Hudler, Melanie; Schrimpf, Daniel; Zadeh, Gelareh; Aldape, Ken; Herold-Mende, Christel; Beck, Katja; Staszewski, Ori; Prinz, Marco; Harosh, Carmit Ben; Eils, Roland; Sturm, Dominik; Jones, David T. W.; Pfister, Stefan M.; Paulus, Werner; Ram, Zvi; Schlesner, Matthias; [...]

Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature

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Springer Science and Business Media LLC, 2017

Published in: Acta Neuropathologica, 134 (2017) 1, Seite 155-158
Sahm, Felix; Schrimpf, Daniel; Jones, David T. W.; Meyer, Jochen; Kratz, Annekathrin; Reuss, David; Capper, David; Koelsche, Christian; Korshunov, Andrey; Wiestler, Benedikt; Buchhalter, Ivo; Milde, Till; Selt, Florian; Sturm, Dominik; Kool, Marcel; Hummel, Manuela; Bewerunge-Hudler, Melanie; Mawrin, Christian; Schüller, Ulrich; Jungk, Christine; Wick, Antje; Witt, Olaf; Platten, Michael; Herold-Mende, Christel; [...]

Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets

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Springer Science and Business Media LLC, 2016

Published in: Acta Neuropathologica, 131 (2016) 6, Seite 903-910
Groebner, Susanne N.; Worst, Barbara; Jones, David T.W.; Buchhalter, Ivo; Kleinheinz, Kortine; Weischenfeldt, Joachim; Johann, Pascal D.; Segura-Wang, Maia; Northcott, Paul A.; Kool, Marcel; Hutter, Barbara; Bender, Sebastian; Korbel, Jan O.; Schlesner, Matthias; Chavez, Lukas; Zapatka, Marc; Lichter, Peter; Pfister, Stefan M.

TB-17A COMPREHENSIVE PAN-CANCER ANALYSIS OF CHILDHOOD MALIGNANCIES

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Oxford University Press (OUP), 2016

Published in: Neuro-Oncology, 18 (2016) suppl 3, Seite iii171.3-iii172
Kool, Marcel; Jäger, Natalie; Sturm, Dominik; Jones, David T.W.; Hoverstadt, Volker; Buchhalter, Ivo; Johann, Pascal; Schmidt, Christin; Ryzhova, Marina; Northcott, Paul A.; Landgraf, Pablo; Remke, Marc; Taylor, Michael D.; Hasselblatt, Martin; Schüller, Ulrich; Huang, Annie; Yaspo, Marie-Laure; Deimling, Andreas von; Eils, Roland; Lichter, Peter; Korshunov, Andrey; Pfister, Stefan M.

Abstract 3093: Unravelling the biology of aggressive and therapy-resistant embryonal tumors with multilayered rosettes (ETMR)

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American Association for Cancer Research (AACR), 2014

Published in: Cancer Research, 74 (2014) 19_Supplement, Seite 3093-3093
Volckmar, Anna‐Lena; Leichsenring, Jonas; Kirchner, Martina; Christopoulos, Petros; Neumann, Olaf; Budczies, Jan; Morais de Oliveira, Cristiano Manuel; Rempel, Eugen; Buchhalter, Ivo; Brandt, Regine; Allgäuer, Michael; Talla, Suranand Babu; von Winterfeld, Moritz; Herpel, Esther; Goeppert, Benjamin; Lier, Amelie; Winter, Hauke; Brummer, Tilman; Fröhling, Stefan; Faehling, Martin; Fischer, Jürgen R.; Heußel, Claus Peter; Herth, Felix; Lasitschka, Felix; [...]

Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases

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Wiley, 2019

Published in: International Journal of Cancer, 145 (2019) 3, Seite 649-661

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