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  1. Delang, Leen [Author]; Harak, Christian [Author]; Benkheil, Mohammed [Author]; Khan, Hayat [Author]; Leyssen, Pieter [Author]; Andrews, Martin [Author]; Lohmann, Volker [Author]; Neyts, Johan [Author]

    PI4KIII inhibitor enviroxime impedes the replication of the hepatitis C virus by inhibiting PI3 kinases

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    14 September 2018

    Published in: The journal of antimicrobial chemotherapy ; 73(2018), 12, Seite 3375-3384

  2. Reiss, Simon [Other]; Harak, Christian [Other]; Romero-Brey, Inés [Other]; Radujković, Danijela [Other]; Klein, Rahel [Other]; Ruggieri, Alessia [Other]; Rebhan, Ilka [Other]; Bartenschlager, Ralf [Other]; Lohmann, Volker [Other]

    The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A

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    2013

    Published in: Public Library of Science: PLoS pathogens ; 9(2013), 5, Artikel-ID e1003359, Seite 1-25

  3. Berger, Carola [Other]; Romero-Brey, Inés [Other]; Radujković, Danijela [Other]; Zayas López, Margarita Laura [Other]; Paul, David [Other]; Harak, Christian [Other]; Hoppe, Simone [Other]; Lohmann, Volker [Other]; Bartenschlager, Ralf [Other]

    Daclatasvir-like inhibitors of NS5A block early biogenesis of Hepatitis C virus-induced membranous replication factories, independent of RNA replication

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    2014

    Published in: Gastroenterology ; 147(2014,5) S. 1094-1105, e1-e25

  4. Esser-Nobis, Katharina [Other]; Stremmel, Wolfgang [Other]; Eisenbach, Christoph [Other]; Lohmann, Volker [Other]; Romero-Brey, Inés [Other]; Ganten, Tom M. [Other]; Harak, Christian [Other]; Klein, Rahel [Other]; Schemmer, Peter [Other]; Binder, Marco [Other]; Schnitzler, Paul [Other]; Bartenschlager, Ralf [Other]

    Analysis of hepatitis C virus resistance to Silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B

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    2013

    Published in: Hepatology ; 57(2013), 3, Seite 953–963

  10. Harak, Christian; Radujkovic, Danijela; Taveneau, Cyntia; Reiss, Simon; Klein, Rahel; Bressanelli, Stéphane; Lohmann, Volker

    Mapping of Functional Domains of the Lipid Kinase Phosphatidylinositol 4-Kinase Type III Alpha Involved in Enzymatic Activity and Hepatitis C Virus Replication

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    American Society for Microbiology, 2014

    Published in: Journal of Virology

  12. Dorobantu, Cristina M.; Harak, Christian; Klein, Rahel; van der Linden, Lonneke; Strating, Jeroen R. P. M.; van der Schaar, Hilde M.; Lohmann, Volker; van Kuppeveld, Frank J. M.

    Tyrphostin AG1478 Inhibits Encephalomyocarditis Virus and Hepatitis C Virus by Targeting Phosphatidylinositol 4-Kinase IIIα

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    American Society for Microbiology, 2016

    Published in: Antimicrobial Agents and Chemotherapy

  13. Berger, Carola; Romero-Brey, Inés; Radujkovic, Danijela; Terreux, Raphael; Zayas, Margarita; Paul, David; Harak, Christian; Hoppe, Simone; Gao, Min; Penin, Francois; Lohmann, Volker; Bartenschlager, Ralf

    Daclatasvir-Like Inhibitors of NS5A Block Early Biogenesis of Hepatitis C Virus–Induced Membranous Replication Factories, Independent of RNA Replication

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    Elsevier BV, 2014

    Published in: Gastroenterology

  14. Dorobantu, Cristina M.; Albulescu, Lucian; Lyoo, Heyrhyoung; van Kampen, Mirjam; De Francesco, Raffaele; Lohmann, Volker; Harak, Christian; van der Schaar, Hilde M.; Strating, Jeroen R. P. M.; Gorbalenya, Alexander E.; van Kuppeveld, Frank J. M.

    Mutations in Encephalomyocarditis Virus 3A Protein Uncouple the Dependency of Genome Replication on Host Factors Phosphatidylinositol 4-Kinase IIIα and Oxysterol-Binding Protein

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    American Society for Microbiology, 2016

    Published in: mSphere

  15. Dorobantu, Cristina M.; Albulescu, Lucian; Harak, Christian; Feng, Qian; van Kampen, Mirjam; Strating, Jeroen R. P. M.; Gorbalenya, Alexander E.; Lohmann, Volker; van der Schaar, Hilde M.; van Kuppeveld, Frank J. M.

    Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus

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    Public Library of Science (PLoS), 2015

    Published in: PLOS Pathogens

  16. Esser-Nobis, Katharina; Romero-Brey, Inés; Ganten, Tom M.; Gouttenoire, Jérôme; Harak, Christian; Klein, Rahel; Schemmer, Peter; Binder, Marco; Schnitzler, Paul; Moradpour, Darius; Bartenschlager, Ralf; Polyak, Stephen J.; Stremmel, Wolfgang; Penin, François; Eisenbach, Christoph; Lohmann, Volker

    Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B

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    Ovid Technologies (Wolters Kluwer Health), 2013

    Published in: Hepatology