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Hargrave, Darren R. [Author]; Terashima, Keita [Author]; Hara, Junichi [Author]; Kordes, Uwe R. [Author]; Upadhyaya, Santhosh A. [Author]; Sahm, Felix [Author]; Bouffet, Eric [Author]; Packer, Roger J. [Author]; Witt, Olaf [Author]; Sandalic, Larissa [Author]; Kieloch, Agnieszka [Author]; Russo, Mark [Author]; Cohen, Kenneth J. [Author]

Phase II trial of dabrafenib plus trametinib in relapsed/refractory BRAF V600-mutant pediatric high-grade glioma

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August 29, 2023

Published in: Journal of clinical oncology ; 41(2023), 33 vom: Nov., Seite 5174-5183
Hargrave, Darren R.; Hargrave, Ursula A.; Bouffet, Eric

Quality of health information on the Internet in pediatric neuro-oncology

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Oxford University Press (OUP), 2006

Published in: Neuro-Oncology, 8 (2006) 2, Seite 175-182
Angelini, Paola; Pritchard-Jones, Kathryn; Hargrave, Darren R

Challenges in incentivizing the pharmaceutical industry to supporting pediatric oncology clinical trials

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OMICS Publishing Group, 2013

Published in: Clinical Investigation, 3 (2013) 2, Seite 101-103
Hargrave, Darren R.; Mabbott, Donald J.; Bouffet, Eric

Pathological laughter and behavioural change in childhood pontine glioma

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Springer Science and Business Media LLC, 2006

Published in: Journal of Neuro-Oncology, 77 (2006) 3, Seite 267-271
Lau, Loretta; Hargrave, Darren R.; Bartels, Ute; Esquembre, Carlos; Bouffet, Eric

Childhood brain tumour information on the Internet in the Chinese language

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Springer Science and Business Media LLC, 2006

Published in: Child's Nervous System, 22 (2006) 4, Seite 346-351
Hargrave, Darren R.; Wade, Angie; Evans, Jane P. M.; Hewes, Deborah K. M.; Kirkham, Fenella J.

Nocturnal oxygen saturation and painful sickle cell crises in children

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American Society of Hematology, 2003

Published in: Blood, 101 (2003) 3, Seite 846-848
Hargrave, Darren R.; Bouffet, Eric; Gammon, Janet; Tariq, Nauman; Grant, Ron M.; Baruchel, Sylvain

Phase I study of fotemustine in pediatric patients with refractory brain tumors

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Wiley, 2002

Published in: Cancer, 95 (2002) 6, Seite 1294-1301
Veldhuijzen van Zanten, Sophie E. M.; Cruz, Ofelia; Kaspers, Gertjan J. L.; Hargrave, Darren R.; van Vuurden, Dannis G.

State of affairs in use of steroids in diffuse intrinsic pontine glioma: an international survey and a review of the literature

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Springer Science and Business Media LLC, 2016

Published in: Journal of Neuro-Oncology, 128 (2016) 3, Seite 387-394
Chalmers, Anthony J.; Jackson, Alan; Swaisland, Helen; Stewart, William; Halford, Sarah E. R.; Molife, L Rhoda; Hargrave, Darren R; McCormick, Alex

Results of stage 1 of the oparatic trial: A phase I study of olaparib in combination with temozolomide in patients with relapsed glioblastoma

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American Society of Clinical Oncology (ASCO), 2014

Published in: Journal of Clinical Oncology, 32 (2014) 15_suppl, Seite 2025-2025
Alrashdi, Ismail; Levine, Samantha; Paterson, Joan; Saxena, Rohit; Patel, Soonie R.; Depani, Sarita; Hargrave, Darren R.; Pritchard-Jones, Kathy; Hodgson, Shirley V.

Hereditary leiomyomatosis and renal cell carcinoma: very early diagnosis of renal cancer in a paediatric patient

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Springer Science and Business Media LLC, 2010

Published in: Familial Cancer, 9 (2010) 2, Seite 239-243
Bull, Kim S; Hornsey, Samantha; Kennedy, Colin R; Darlington, Anne-Sophie E; Grootenhuis, Martha A; Hargrave, Darren; Liossi, Christina; Shepherd, Jonathan P; Walker, David A; Morris, Christopher

Systematic review: measurement properties of patient-reported outcome measures evaluated with childhood brain tumor survivors or other acquired brain injury

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Oxford University Press (OUP), 2020

Published in: Neuro-Oncology Practice, 7 (2020) 3, Seite 277-287
Pearson, Andrew DJ; Federico, Sara Michele; Aerts, Isabelle; Hargrave, Darren R; DuBois, Steven G.; Iannone, Robert; Geschwindt, Ryan; Wang, Ruixue; Trippett, Tanya M.; Geoerger, Birgit

A phase I study of ridaforolimus (MK-8669) in pediatric patients with advanced solid tumors

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American Society of Clinical Oncology (ASCO), 2013

Published in: Journal of Clinical Oncology, 31 (2013) 15_suppl, Seite 10027-10027
Viana-Pereira, Marta; Lee, Alicia; Popov, Sergey; Bax, Dorine A.; Al-Sarraj, Safa; Bridges, Leslie R.; Stávale, João N.; Hargrave, Darren; Jones, Chris; Reis, Rui M.

Microsatellite Instability in Pediatric High Grade Glioma Is Associated with Genomic Profile and Differential Target Gene Inactivation

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Public Library of Science (PLoS), 2011

Published in: PLoS ONE, 6 (2011) 5, Seite e20588
Rapley, Elizabeth A.; Hargrave, Darren; Persinguhe, Nina; Barfoot, Rita; Moore, Isobel; Radford, Martin; Stratton, Michael R.; Rahman, Nazneen; Pritchard-Jones, Kathy

Case of interstitial 12q deletion in association with Wilms tumor

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Wiley, 2001

Published in: American Journal of Medical Genetics, 104 (2001) 3, Seite 246-249
Rapley, Elizabeth A.; Hargrave, Darren; Persinguhe, Nina; Barfoot, Rita; Moore, Isobel; Radford, Martin; Stratton, Michael R.; Rahman, Nazneen; Pritchard‐Jones, Kathy

Case of interstitial 12q deletion in association with Wilms tumor

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Wiley, 2001

Published in: American Journal of Medical Genetics, 104 (2001) 3, Seite 246-249
Hargrave, Darren R.; Terashima, Keita; Hara, Junichi; Kordes, Uwe R.; Upadhyaya, Santhosh A.; Sahm, Felix; Bouffet, Eric; Packer, Roger J.; Witt, Olaf; Sandalic, Lali; Kieloch, Agnieszka; Russo, Mark W.; Cohen, Kenneth J.

Dabrafenib + trametinib (dab + tram) in relapsed/refractory (r/r) BRAF V600–mutant pediatric high-grade glioma (pHGG): Primary analysis of a phase II trial

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American Society of Clinical Oncology (ASCO), 2022

Published in: Journal of Clinical Oncology, 40 (2022) 16_suppl, Seite 2009-2009
Chi, Susan N.; Bourdeaut, Franck; Casanova, Michela; Kilburn, Lindsay Baker; Hargrave, Darren R.; McCowage, Geoffrey Brian; Pinto, Navin R.; Yang, Jay; Chadha, Raminder; Kahali, Bhaskar; Tapia, Coya; Nysom, Karsten

Update on phase 1 study of tazemetostat, an enhancer of zeste homolog 2 inhibitor, in pediatric patients with relapsed or refractory integrase interactor 1–negative tumors

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American Society of Clinical Oncology (ASCO), 2022

Published in: Journal of Clinical Oncology, 40 (2022) 16_suppl, Seite 10040-10040
Hargrave, Darren R.; Bouffet, Eric; Tabori, Uri; Broniscer, Alberto; Cohen, Kenneth J.; Hansford, Jordan R.; Geoerger, Birgit; Hingorani, Pooja; Dunkel, Ira J.; Russo, Mark W.; Tseng, Lillian; Dasgupta, Kohinoor; Gasal, Eduard; Whitlock, James A.; Kieran, Mark W.

Efficacy and Safety of Dabrafenib in Pediatric Patients with BRAF V600 Mutation–Positive Relapsed or Refractory Low-Grade Glioma: Results from a Phase I/IIa Study

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American Association for Cancer Research (AACR), 2019

Published in: Clinical Cancer Research, 25 (2019) 24, Seite 7303-7311
Fangusaro, Jason R.; Locatelli, Franco; Garré, Maria Luisa; Marshall, Lynley V.; Massimino, Maura; Benettaib, Bouchra; Biserna, Noha; Poon, Jennifer; Quan, Jackie; Conlin, Erin; Lewandowski, John; Simcock, Mathew; Jeste, Neelum; Hargrave, Darren R; Doz, Francois P.; Warren, Katherine E.

A phase II clinical study of pomalidomide (CC-4047) monotherapy for children and young adults with recurrent or progressive primary brain tumors

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American Society of Clinical Oncology (ASCO), 2019

Published in: Journal of Clinical Oncology, 37 (2019) 15_suppl, Seite 10035-10035
Hargrave, Darren R; Pearson, Andrew DJ; Moreno, Lucas; Morland, Bruce; Elliott, Martin; Makin, Guy; Campbell-Hewson, Quentin; Wyld, Peter J.; Halford, Sarah E. R.; Lock, Victoria; Lyons, John F.; Boddy, Alan V.; Yule, Murray

A phase I trial of AT9283 (a selective inhibitor of Aurora kinases) given for 72 hours every 21 days via intravenous infusion in children and adolescents with relapsed and refractory solid tumours

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American Society of Clinical Oncology (ASCO), 2012

Published in: Journal of Clinical Oncology, 30 (2012) 15_suppl, Seite 9542-9542

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