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  1. Stintzing, Sebastian; Jung, Andreas; Rossius, Lisa; Modest, Dominik Paul; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Al-Batran, Salah-Eddin; Vehling-Kaiser, Ursula; Heintges, Tobias; Moehler, Markus; Scheithauer, Werner; Kirchner, Thomas; Heinemann, Volker

    Mutations within the EGFR signaling pathway: Influence on efficacy in FIRE-3—A randomized phase III study of FOLFIRI plus cetuximab or bevacizumab as first-line treatment for wild-type (WT) KRAS (exon 2) metastatic colorectal cancer (mCRC) patients

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    American Society of Clinical Oncology (ASCO), 2014

    Published in: Journal of Clinical Oncology, 32 (2014) 3_suppl, Seite 445-445

  2. Liu, Lian; Erickson, Nicole Tonya; Ricard, Ingrid; von Weikersthal, Ludwig Fischer; Lerch, Markus M.; Decker, Thomas; Kiani, Alexander; Kaiser, Florian; Heintges, Tobias; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Link, Hartmut; Höffkes, Heinz‐Gert; Moehler, Markus; Gesenhues, Alena Britta; Theurich, Sebastian; Michl, Marlies; Modest, Dominik P.; Algül, Hana; Stintzing, Sebastian; Heinemann, Volker; Holch, Julian W.

    Early weight loss is an independent risk factor for shorter survival and increased side effects in patients with metastatic colorectal cancer undergoing first‐line treatment within the randomized Phase III trial FIRE‐3 (AIO KRK‐0306)

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    Wiley, 2022

    Published in: International Journal of Cancer, 150 (2022) 1, Seite 112-123

  3. Holch, Julian Walter; Ricard, Ingrid; Stintzing, Sebastian; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling‐Kaiser, Ursula; Al‐Batran, Salah‐Eddin; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Scholz, Michael; Müller, Sebastian; Link, Hartmut; Rost, Andreas; Höffkes, Heinz‐Gert; Moehler, Markus; Lindig, Reinhard Udo; Miller‐Phillips, Lisa; Kirchner, Thomas; Jung, Andreas; von Einem, Jobst Christian; [...]

    Relevance of liver‐limited disease in metastatic colorectal cancer: Subgroup findings of the FIRE‐3/AIO KRK0306 trial

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    Wiley, 2018

    Published in: International Journal of Cancer, 142 (2018) 5, Seite 1047-1055

  4. Michl, Marlies; Fischer von Weikersthal, Ludwig; Crispin, Alexander; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmuller, Christian A.; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Hielscher, Joerg; Scholz, Michael; Mueller, Sebastian; Modest, Dominik Paul; Stintzing, Sebastian; Heinemann, Volker

    AIO KRK0306, FIRE3 trial: CEA and CA19-9 influence outcome of patients with KRAS exon wild-type metastatic colorectal cancer (mCRC) receiving first-line therapy with FOLFIRI plus cetuximab or bevacizumab

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    American Society of Clinical Oncology (ASCO), 2014

    Published in: Journal of Clinical Oncology, 32 (2014) 15_suppl, Seite 3592-3592

  5. Modest, Dominik; von Weikersthal, Ludwig Fischer; Stintzing, Sebastian; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al Batran, Salah-Eddin; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Hielscher, Jörg; Scholz, Michael; Müller, Sebastian; Schäfer, Britta; Jung, Andreas; Heinemann, Volker

    FOLFIRI Plus Cetuximab Versus Folfiri Plus Bevacizumab as First-Line Treatment of KRAS-Wildtype Metastatic Colorectal Cancer: German AIO Study Krk-0306 (FIRE-3)

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    Elsevier BV, 2013

    Published in: Annals of Oncology, 24 (2013), Seite iv22

  6. Heinemann, Volker; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmueller, Juergen; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Hielscher, Joerg; Scholz, Michael; Mueller, Sebastian; Schaefer, Britta; Modest, Dominik Paul; Jung, Andreas; Stintzing, Sebastian

    Randomized comparison of FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment of KRAS wild-type metastatic colorectal cancer: German AIO study KRK-0306 (FIRE-3)

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    American Society of Clinical Oncology (ASCO), 2013

    Published in: Journal of Clinical Oncology, 31 (2013) 18_suppl, Seite LBA3506-LBA3506

  7. Heinemann, Volker; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmueller, Juergen; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Hielscher, Joerg; Scholz, Michael; Mueller, Sebastian; Schaefer, Britta; Modest, Dominik Paul; Jung, Andreas; Stintzing, Sebastian

    Randomized comparison of FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment of KRAS-wildtype metastatic colorectal cancer: German AIO study KRK-0306 (FIRE-3)

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    American Society of Clinical Oncology (ASCO), 2013

    Published in: Journal of Clinical Oncology, 31 (2013) 15_suppl, Seite LBA3506-LBA3506

  8. Stahler, Arndt; Modest, Dominik Paul; Stintzing, Sebastian; Held, Swantje; Fischer von Weikersthal, Ludwig; Müller, Lothar; Graeven, Ullrich; Decker, Thomas; Heintges, Tobias; Kahl, Christoph; Scheithauer, Werner; Kiani, Alexander; Kaiser, Florian; Schwaner, Ingo; Fruehauf, Stefan; Karthaus, Meinolf; Trarbach, Tanja; Klauschen, Frederik; Horst, David; Heinemann, Volker

    Consensus molecular subtypes (CMS) as prognostic and predictive biomarkers of RAS wild-type (WT) metastatic colorectal cancer (mCRC): Pooled analysis of the randomized trials FIRE-1, FIRE-3, XELAVIRI, and PanaMa

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    American Society of Clinical Oncology (ASCO), 2024

    Published in: Journal of Clinical Oncology, 42 (2024) 16_suppl, Seite 3529-3529

  9. Weiss, Lena; Stintzing, Sebastian; Modest, Dominik Paul; von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmuller, Christian A.; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Moehler, Markus H.; Scheithauer, Werner; Held, Swantje; Miller-Phillips, Lisa; Stahler, Arndt; Jung, Andreas; Heinemann, Volker

    Efficacy of FOLFIRI plus bevacizumab versus FOLFIRI plus cetuximab in RAS-mutant metastatic colorectal cancer: Final update on patients with RAS-mutant metastatic colorectal cancer treated in FIRE-3

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    American Society of Clinical Oncology (ASCO), 2024

    Published in: Journal of Clinical Oncology, 42 (2024) 16_suppl, Seite 3550-3550

  10. Holch, Julian Walter; Ohnmacht, Alexander; Stintzing, Sebastian; Heinrich, Kathrin; Westphalen, Benedikt; Weiss, Lena; von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Kaiser, Florian; Heintges, Tobias; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Link, Hartmut; Hoeffkes, Heinz-Gert; Moehler, Markus H.; Modest, Dominik Paul; Menden, Michael; Heinemann, Volker

    Refining first-line treatment decision in RAS wildtype (RAS-WT) metastatic colorectal cancer (mCRC) by combining clinical biomarkers: Results of the randomized phase 3 trial FIRE-3 (AIO KRK0306)

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    American Society of Clinical Oncology (ASCO), 2024

    Published in: Journal of Clinical Oncology, 42 (2024) 3_suppl, Seite 13-13

  11. Fischer, Laura E.; Stintzing, Sebastian; von Weikersthal, Ludwig Fischer; Modest, Dominik P.; Decker, Thomas; Kiani, Alexander; Kaiser, Florian; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmüller, Christian; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Giessen-Jung, Clemens; Uhlig, Jens; Peuser, Bettina; Denzlinger, Claudio; Stahler, Arndt; Weiss, Lena; Heinrich, Kathrin; Held, Swantje; Jung, Andreas; [...]

    Efficacy of FOLFIRI plus cetuximab vs FOLFIRI plus bevacizumab in 1st-line treatment of older patients with RAS wild-type metastatic colorectal cancer: an analysis of the randomised trial FIRE-3

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    Springer Science and Business Media LLC, 2022

    Published in: British Journal of Cancer, 127 (2022) 5, Seite 836-843

  12. Hofmann, Felix O.; Heinemann, Volker; D’Anastasi, Melvin; Gesenhues, Alena B.; Hesse, Nina; von Weikersthal, Ludwig Fischer; Decker, Thomas; Kiani, Alexander; Moehler, Markus; Kaiser, Florian; Heintges, Tobias; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Link, Hartmut; Modest, Dominik P.; Stintzing, Sebastian; Holch, Julian W.

    Standard diametric versus volumetric early tumor shrinkage as a predictor of survival in metastatic colorectal cancer: subgroup findings of the randomized, open-label phase III trial FIRE-3 / AIO KRK-0306

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    Springer Science and Business Media LLC, 2022

    Published in: European Radiology, 33 (2022) 2, Seite 1174-1184

  13. Heinemann, Volker; von Weikersthal, Ludwig Fischer; Decker, Thomas; Kiani, Alexander; Kaiser, Florian; Al-Batran, Salah-Edin; Heintges, Tobias; Lerchenmüller, Christoph; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Moehler, Markus; Scheithauer, Werner; Held, Swantje; Miller-Phillips, Lisa; Modest, Dominik Paul; Jung, Andreas; Kirchner, Thomas; Stintzing, Sebastian

    FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial

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    Springer Science and Business Media LLC, 2021

    Published in: British Journal of Cancer, 124 (2021) 3, Seite 587-594

  14. von Einem, Jobst C.; Stintzing, Sebastian; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmuller, Christian A.; Kahl, Christoph; Seipelt, Gernot; Stauch, Martina; Scheithauer, Werner; Hielscher, Joerg; Scholz, Michael; Modest, Dominik Paul; Jung, Andreas; Kirchner, Thomas; Heinemann, Volker

    Prognostic importance of primary tumor resection and synchronous metastasis on overall survival in metastatic colorectal cancer: Data from the FIRE-3 (AIO KRK-0306) study

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    American Society of Clinical Oncology (ASCO), 2020

    Published in: Journal of Clinical Oncology, 38 (2020) 15_suppl, Seite 4070-4070

  15. Stahler, Arndt; Stintzing, Sebastian; Modest, Dominik Paul; Jelas, Ivan; Heinrich, Kathrin; Miller-Phillips, Lisa; von Einem, Jobst C.; Vehling-Kaiser, Ursula; Decker, Thomas; Kiani, Alexander; Fischer von Weikersthal, Ludwig; Heintges, Tobias; Kahl, Christoph; Kullmann, Frank; Scheithauer, Werner; Moehler, Markus H.; Wirapati, Pratyaksha; Kirchner, Thomas; Jung, Andreas; Heinemann, Volker

    Association of MAPK signaling subtypes with prognostic benefit for bevacizumab in left-sided metastatic colorectal cancer (mCRC) patients treated with FOLFIRI + cetuximab / bevacizumab (FIRE-3 trial)

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    American Society of Clinical Oncology (ASCO), 2019

    Published in: Journal of Clinical Oncology, 37 (2019) 15_suppl, Seite 3584-3584

  16. Heinemann, Volker; Modest, Dominik Paul; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Kaiser, Florian; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmuller, Christian A.; Kahl, Christoph; Seipelt, Gernot; Kullmann, Frank; Stauch, Martina; Scheithauer, Werner; Held, Swantje; Jung, Andreas; Kirchner, Thomas; Stintzing, Sebastian

    Effect of patient age on efficacy of FOLFIRI plus cetuximab vs bevacizumab in 1st-line treatment of metastatic colorectal cancer: An analysis of FIRE-3 (AIO KRK 0306)

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    American Society of Clinical Oncology (ASCO), 2019

    Published in: Journal of Clinical Oncology, 37 (2019) 15_suppl, Seite 3541-3541

  17. Heinemann, Volker; Kraemer, Nicole; Buchner, Hannes; Fischer von Weikersthal, Ludwig; Decker, Thomas; Kiani, Alexander; Vehling-Kaiser, Ursula; Al-Batran, Salah-Eddin; Heintges, Tobias; Lerchenmuller, Christian A.; Kahl, Christoph; Kullmann, Frank; Moehler, Markus H.; Scheithauer, Werner; Held, Swantje; Modest, Dominik Paul; Neumann, Jens; Jung, Andreas; Kirchner, Thomas; Stintzing, Sebastian

    Somatic DNA mutations, tumor mutational burden (TMB), and MSI Status: Association with efficacy in patients (pts) with metastatic colorectal cancer (mCRC) of FIRE-3 (AIO KRK-0306)

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    American Society of Clinical Oncology (ASCO), 2018

    Published in: Journal of Clinical Oncology, 36 (2018) 15_suppl, Seite 3591-3591