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Leist, Marcel [Author]; Lidbury, Brett A. [Author]; Yang, Chihae [Author] ; Hayden, Patrick J. [Other]; Kelm, Jens M. [Other]; Ringeissen, Stephanie [Other]; Detroyer, Ann [Other]; Meunier, Jean R. [Other]; Rathman, James F. [Other]; Jackson, George R. [Other]; Stolper, Gina [Other]; Hasiwa, Nina [Other]

Novel Technologies and an Overall Strategy to Allow Hazard Assessment and Risk Prediction of Chemicals, Cosmetics, and Drugs with Animal-Free Methods

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Konstanz: Bibliothek der Universität Konstanz, 2012
Alepee, Natalie [Author]; Bahinski, Tony [Author]; Daneshian, Mardas [Author] ; Wever, Bart de [Other]; Kadereit, Suzanne [Other]; McVey, Emily A. [Other]; Landsiedel, Robert [Other]; Leist, Marcel [Other]; Lubberstedt, Marc [Other]; Noor, Fozia [Other]; Pellevoisin, Christian [Other]; Petersohn, Dirk [Other]; Pfannenbecker, Uwe [Other]; Reisinger, Kerstin [Other]; Fritsche, Ellen [Other]; Ramirez, Tzutzuy [Other]; Rothen-Rutishauser, Barbara Maria [Other]; Schafer-Korting, Monika [Other]; Zeilinger, Katrin [Other]; Zurich, Marie-Gabriele [Other]; Goldberg, Alan [Other]; Hansmann, Jan [Other]; Hartung, Thomas [Other]; Haycock, John [Other]; Hogberg, Helena T. [Other]; Hölting, Lisa [Other]; Kelm, Jens M. [Other]

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology

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Konstanz: Bibliothek der Universität Konstanz, 2014
Kelm, Jens M.; Marchan, Rosemarie

Progress in ‘body-on-a-chip’ research

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Springer Science and Business Media LLC, 2014

Published in: Archives of Toxicology, 88 (2014) 11, Seite 1913-1914
Messner, Simon; Strube, Randy; Roessger, Katrin; Kelm, Jens M.

Mitotoxicity Testing in 3D Liver Microtissues : Novel Two-Step Assay Integrates Toxicity Testing in 3D Liver Models and Assessment of OCR : Novel Two-Step Assay Integrates Toxicity Testing in 3D Liver Models and Assessment of OCR

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Mary Ann Liebert Inc, 2016

Published in: Genetic Engineering & Biotechnology News, 36 (2016) 16, Seite 24-25
Thuruthippallil, Leena Mol; Kelm, Jens M.; Fluri, David

Abstract B75: High-throughput, bright-field imaging of 3D tumor spheroid growth and morphology for therapeutic and efficacy screening: A study using chemotherapeutic compounds

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American Association for Cancer Research (AACR), 2015

Published in: Molecular Cancer Therapeutics, 14 (2015) 12_Supplement_2, Seite B75-B75
Letzsch, Stefan; Boettcher, Karin; Kelm, Jens M.; Messner, Simon

Quantifying Efflux Activity in 3D Liver Spheroids : New Confocal Imaging Instruments Allow Screening in Complex Human Liver Microtissues : New Confocal Imaging Instruments Allow Screening in Complex Human Liver Microtissues

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Mary Ann Liebert Inc, 2015

Published in: Genetic Engineering & Biotechnology News, 35 (2015) 7, Seite 14-15
Waschow, Marcel; Drewitz, Maren; Böttcher, Karin; Kelm, Jens M.

High-content-Analyse von 3D-Zellkulturen : Medikamentenentwicklung : Medikamentenentwicklung

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Springer Science and Business Media LLC, 2012

Published in: BIOspektrum, 18 (2012) 4, Seite 447-448
Kim, Jin-Young; Fluri, David A.; Kelm, Jens M.; Hierlemann, Andreas; Frey, Olivier

96-Well Format-Based Microfluidic Platform for Parallel Interconnection of Multiple Multicellular Spheroids

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Elsevier BV, 2015

Published in: SLAS Technology, 20 (2015) 3, Seite 274-282
Strube, Randy; Fernandes, Andreia F.; Furter, Markus; Kelm, Jens M.; Fluri, David A.

Phenotypic Drug Discovery in 3D : Testing Drug Efficacy by Rapid Size Profiling Over Time with Tumor Microtissues : Testing Drug Efficacy by Rapid Size Profiling Over Time with Tumor Microtissues

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Mary Ann Liebert Inc, 2014

Published in: Genetic Engineering & Biotechnology News, 34 (2014) 16, Seite 18-19
Thoma, Claudio R.; Stroebel, Simon; Rösch, Nora; Calpe, Blaise; Krek, Wilhelm; Kelm, Jens M.

A High-Throughput–Compatible 3D Microtissue Co-Culture System for Phenotypic RNAi Screening Applications

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Elsevier BV, 2013

Published in: SLAS Discovery, 18 (2013) 10, Seite 1330-1337
Drewitz, Maren; Salomon, Michael; Thirion, Christian; Oberdanner, Christian; Kelm, Jens M.

Abstract LB-113: Non-invasive analysis of drug sensitivity in homo and-heterotypic multicellular tumor spheroids

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American Association for Cancer Research (AACR), 2012

Published in: Cancer Research, 72 (2012) 8_Supplement, Seite LB-113-LB-113
Drewitz, Maren; Caminada, Daniel; Moritz, Wolfgang; Lichtenberg, Jan; Kasper, Cornelia; Kelm, Jens M.

Novel Production Technology to Automate the Generation of Hanging Drops for Mass Production of Organotypic Microtissues

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Wiley, 2011

Published in: Chemie Ingenieur Technik, 83 (2011) 12, Seite 2170-2176
Drewitz, Maren; Helbling, Marianne; Fried, Nicole; Bieri, Manuela; Moritz, Wolfgang; Lichtenberg, Jan; Kelm, Jens M.

Towards automated production and drug sensitivity testing using scaffold‐free spherical tumor microtissues

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Wiley, 2011

Published in: Biotechnology Journal, 6 (2011) 12, Seite 1488-1496
Sanchez-Bustamante, Carlota Diaz; Frey, Urs; Kelm, Jens M.; Hierlemann, Andreas; Fussenegger, Martin

Modulation of Cardiomyocyte Electrical Properties Using Regulated Bone Morphogenetic Protein-2 Expression

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Mary Ann Liebert Inc, 2008

Published in: Tissue Engineering Part A, 14 (2008) 12, Seite 1969-1988
Fluri, David A.; Kelm, Jens M.; Lesage, Guillaume; Baba, Marie Daoud‐El; Fussenegger, Martin

InXy and SeXy, compact heterologous reporter proteins for mammalian cells

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Wiley, 2007

Published in: Biotechnology and Bioengineering, 98 (2007) 3, Seite 655-667
Sanchez‐Bustamante, Carlota Diaz; Kelm, Jens M.; Mitta, Barbara; Fussenegger, Martin

Heterologous protein production capacity of mammalian cells cultivated as monolayers and microtissues

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Wiley, 2006

Published in: Biotechnology and Bioengineering, 93 (2006) 1, Seite 169-180
Kelm, Jens M.; Ehler, Elisabeth; Nielsen, Lars K.; Schlatter, Stefan; Perriard, Jean-Claude; Fussenegger, Martin

Design of Artificial Myocardial Microtissues

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Mary Ann Liebert Inc, 2004

Published in: Tissue Engineering, 10 (2004) 1-2, Seite 201-214
Fux, Cornelia; Langer, Dominik; Kelm, Jens M.; Weber, Wilfried; Fussenegger, Martin

New‐generation multicistronic expression platform: pTRIDENT vectors containing size‐optimized IRES elements enable homing endonuclease‐based cistron swapping into lentiviral expression vectors

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Wiley, 2004

Published in: Biotechnology and Bioengineering, 86 (2004) 2, Seite 174-187
Kelm, Jens M.; Kramer, Beat P.; Gonzalez‐Nicolini, Valeria; Ley, Bettina; Fussenegger, Martin

REVIEW: Synergies of microtissue design, viral transduction and adjustable transgene expression for regenerative medicine

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Wiley, 2004

Published in: Biotechnology and Applied Biochemistry, 39 (2004) 1, Seite 3-16
Kelm, Jens M.; Timmins, Nicholas E.; Brown, Catherine J.; Fussenegger, Martin; Nielsen, Lars K.

Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types

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Wiley, 2003

Published in: Biotechnology and Bioengineering, 83 (2003) 2, Seite 173-180

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