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  3. Rahmanto, Aldwin Suryo [Author]; Jones, David T. W. [Author]; Pfister, Stefan [Author]; Kool, Marcel [Author]; Korshunov, Andrey [Author]

    FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

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    13 September 2016

    Published in: European Molecular Biology Organization: The EMBO journal ; 35(2016), 20, Seite 2192-2212

  4. Rack, Paul Geroge [Author]; Hovestadt, Volker [Author]; Kool, Marcel [Author]; Jones, David T. W. [Author]; Pfister, Stefan [Author]

    Arhgap36-dependent activation of Gli transcription factors

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    29 July 2014

    Published in: National Academy of Sciences (Washington, DC): Proceedings of the National Academy of Sciences of the United States of America ; 111(2014), 30, Seite 11061-11066

  5. Gringmuth, Marieke [Author]; Walther, Jenny [Author]; Greiser, Sebastian [Author]; Touissant, Magali [Author]; Schwalm, Benjamin [Author]; Kool, Marcel [Author]; Kortmann, Rolf-Dieter [Author]; Glasow, Annegret [Author]; Patties, Ina [Author]

    Enhanced Survival of High-Risk Medulloblastoma-Bearing Mice after Multimodal Treatment with Radiotherapy, Decitabine, and Abacavir

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    Basel : MDPI, [2024]

  6. Morrissy, A. Sorana [Author]; Hovestadt, Volker [Author]; Jones, David T. W. [Author]; Korshunov, Andrey [Author]; Lichter, Peter [Author]; Kool, Marcel [Author]; Pfister, Stefan [Author]

    Spatial heterogeneity in medulloblastoma

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    10 April 2017

    Published in: Nature genetics ; 49(2017), 5, Seite 780-788

  7. Feng, Weijun [Author]; Kawauchi, Daisuke [Author]; Hanna, Bola [Author]; Korshunov, Andrey [Author]; Jones, David T. W. [Author]; Kool, Marcel [Author]; Lichter, Peter [Author]; Pfister, Stefan [Author]; Liu, Hai-Kun [Author]

    Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme

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    20 Mar 2017

    Published in: Nature Communications ; 8(2017) Artikel-Nummer 14758, 14 Seiten

  8. Kool, Marcel [Author]; Milde, Till [Author]; Witt, Hendrik [Author]; Bartholomä, Cynthia C. [Author]; Kalle, Christof von [Author]; Unterberg, Andreas [Author]; Herold-Mende, Christel [Author]; Kulozik, Andreas [Author]; Deimling, Andreas von [Author]; Scheurlen, Wolfram [Author]; Pfister, Stefan [Author]

    Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

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    17 March 2014

    Published in: Cancer cell ; 25(2014), 3, Seite 393-405

  9. Hovestadt, Volker [Author]; Jones, David T. W. [Author]; Kool, Marcel [Author]; Bartholomä, Cynthia C. [Author]; Kalle, Christof von [Author]; Eils, Jürgen [Author]; Milde, Till [Author]; Witt, Olaf [Author]; Scheurlen, Wolfram [Author]; Brors, Benedikt [Author]; Eils, Roland [Author]; Korshunov, Andrey [Author]; Zapatka, Marc [Author]; Pfister, Stefan [Author]; Lichter, Peter [Author]

    Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

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    2014

    Published in: Nature <London> ; 510(2014), 7506, Seite 537-541

  10. Sturm, Dominik [Other]; Witt, Hendrik [Other]; Jones, David T. W. [Other]; Konermann, Carolin [Other]; Pfaff, Elke [Other]; Bender, Sebastian [Other]; Kool, Marcel [Other]; Becker, Natalia [Other]; Hielscher, Thomas [Other]; Radlwimmer, Bernhard [Other]; Komorowski, Gregor von [Other]; Dürken, Matthias [Other]; Kulozik, Andreas [Other]; Deimling, Andreas von [Other]; Herold-Mende, Christel [Other]; Unterberg, Andreas [Other]; Wiestler, Benedikt [Other]; Wick, Wolfgang [Other]; Milde, Till [Other]; Witt, Olaf [Other]; Korshunov, Andrey [Other]; Lichter, Peter [Other]; Pfister, Stefan [Other]

    Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

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    October 15, 2012

    Published in: Cancer cell ; 22(2012), 4, Seite 425-437

  11. Funke, Viktoria [Author]; Walter, Carolin [Author]; Melcher, Viktoria [Author]; Wei, Lanying [Author]; Sandmann, Sarah [Author]; Hotfilder, Marc [Author]; Varghese, Julian [Author]; Jäger, Natalie [Author]; Kool, Marcel [Author]; Jones, David T. W. [Author]; Pfister, Stefan [Author]; Milde, Till [Author]; Mynarek, Martin [Author]; Rutkowski, Stefan [Author]; Seggewiss, Jochen [Author]; Jeising, Daniela [Author]; de Faria, Flavia W. [Author]; Marquardt, Thorsten [Author]; Albert, Thomas K. [Author]; Schüller, Ulrich [Author]; Kerl, Kornelius [Author]

    Group-specific cellular metabolism in Medulloblastoma

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    05 June 2023

    Published in: Journal of translational medicine ; 21(2023), Artikel-ID 363, Seite 1-16

  12. Luo, Zaili [Author]; Xin, Dazhuan [Author]; Liao, Yunfei [Author]; Berry, Kalen [Author]; Ogurek, Sean [Author]; Zhang, Feng [Author]; Zhang, Liguo [Author]; Zhao, Chuntao [Author]; Rao, Rohit [Author]; Dong, Xinran [Author]; Li, Hao [Author]; Yu, Jianzhong [Author]; Lin, Yifeng [Author]; Huang, Guoying [Author]; Xu, Lingli [Author]; Xin, Mei [Author]; Nishinakamura, Ryuichi [Author]; Yu, Jiyang [Author]; Kool, Marcel [Author]; Pfister, Stefan [Author]; Roussel, Martine F. [Author]; Zhou, Wenhao [Author]; Weiss, William A. [Author]; Andreassen, Paul [Author];

    Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability

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    10 February 2023

    Published in: Nature Communications ; 14(2023), Artikel-ID 762, Seite 1-19

  13. Nabbi, Arash [Author]; Beck, Pengbo [Author]; Delaidelli, Alberto [Author]; Oldridge, Derek A. [Author]; Sudhaman, Sumedha [Author]; Zhu, Kelsey [Author]; Yang, S. Y. Cindy [Author]; Mulder, David T. [Author]; Bruce, Jeffrey P. [Author]; Paulson, Joseph N. [Author]; Raman, Pichai [Author]; Zhu, Yuankun [Author]; Resnick, Adam C. [Author]; Sorensen, Poul H. [Author]; Sill, Martin [Author]; Brabetz, Sebastian [Author]; Lambo, Sander [Author]; Malkin, David [Author]; Johann, Pascal-David [Author]; Kool, Marcel [Author]; Jones, David T. W. [Author]; Pfister, Stefan [Author]; Jäger, Natalie [Author]; Pugh, Trevor J. [Author]

    Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours

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    2023

    Published in: Genome medicine ; 15(2023), Artikel-ID 67, Seite 1-24

  14. Juhnke, Björn-Ole [Author]; Gessi, Marco [Author]; Gerber, Nicolas U. [Author]; Friedrich, Carsten [Author]; Mynarek, Martin [Author]; Bueren, André von [Author]; Haberler, Christine [Author]; Schüller, Ulrich [Author]; Kortmann, Rolf-Dieter [Author]; Timmermann, Beate [Author]; Bison, Brigitte [Author]; Warmuth-Metz, Monika [Author]; Kwiecien, Robert [Author]; Pfister, Stefan [Author]; Spix, Claudia [Author]; Pietsch, Torsten [Author]; Kool, Marcel [Author]; Rutkowski, Stefan [Author]; Hoff, Katja von [Author]

    Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and highdose chemotherapy within the prospective P-HIT trial

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    January 2022

    Published in: Neuro-Oncology ; 24(2022), 1, Seite 127-137

  15. Miele, Evelina [Author]; Po, Agnese [Author]; Mastronuzzi, Angela [Author]; Carai, Andrea [Author]; Besharat, Zein Mersini [Author]; Pediconi, Natalia [Author]; Abballe, Luana [Author]; Catanzaro, Giuseppina [Author]; Sabato, Claudia [Author]; De Smaele, Enrico [Author]; Canettieri, Gianluca [Author]; Di Marcotullio, Lucia [Author]; Vacca, Alessandra [Author]; Mai, Antonello [Author]; Levrero, Massimo [Author]; Pfister, Stefan [Author]; Kool, Marcel [Author]; Giangaspero, Felice [Author]; Locatelli, Franco [Author]; Ferretti, Elisabetta [Author]

    Downregulation of miR-326 and its host gene β-arrestin1 induces pro-survival activity of E2F1 and promotes medulloblastoma growth

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    February 2021

    Published in: Molecular oncology ; 15(2021), 2 vom: Feb., Seite 523-542

  16. Wirthschaft, Peter [Author]; Bode, Julia [Author]; Schönig, Kai [Author]; Breckwoldt, Michael O. [Author]; Schmandke, André [Author]; Pusch, Stefan [Author]; Medenbach, Jan [Author]; Bendszus, Martin [Author]; Schwab, Martin E. [Author]; von Deimling, Andreas [Author]; Kool, Marcel [Author]; Herold-Mende, Christel [Author]; Soni, Himanshu [Author]; Reifenberger, Guido [Author]; Ahrends, Robert [Author]; Tews, Björn [Author]; Dietrich, Fabio [Author]; Krüwel, Thomas [Author]; Fischer, Bernd [Author]; Knobbe-Thomsen, Christiane B. [Author]; Rossetti, Giulia [Author]; Hentschel, Andreas [Author]; Mack, Norman [Author]

    RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas

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    Springer, 2019

    Published in: Acta neuropathologica 138(2), 275 - 293 (2019). doi:10.1007/s00401-019-02021-z

  17. Federico, Aniello [Author]; Thomas, Christian [Author]; Miskiewicz, Katarzyna [Author]; Woltering, Niklas [Author]; Zin, Francesca [Author]; Nemes, Karolina [Author]; Bison, Brigitte [Author]; Johann, Pascal-David [Author]; Hawes, Debra [Author]; Bens, Susanne [Author]; Kordes, Uwe [Author]; Albrecht, Steffen [Author]; Dohmen, Hildegard [Author]; Hauser, Peter [Author]; Keyvani, Kathy [Author]; Landeghem, Frank Karel Hendrik van [Author]; Løbner Lund, Eva [Author]; Scheie, David [Author]; Mawrin, Christian [Author]; Monoranu, Camelia Maria [Author]; Parm Ulhøi, Benedicte [Author]; Pietsch, Torsten [Author]; Reinhard, Harald [Author]; Riemenschneider, Markus Johannes [Author]; [...]

    ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance

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    2022

    Published in: Acta neuropathologica ; 143(2022), 6, Seite 697-711

  18. Suwala, Abigail Kora [Author]; Stichel, Damian [Author]; Schrimpf, Daniel [Author]; Kloor, Matthias [Author]; Wefers, Annika K. [Author]; Reinhardt, Annekathrin [Author]; Maas, Sybren L. N. [Author]; Kratz, Christian P. [Author]; Schweizer, Leonille [Author]; Hasselblatt, Martin [Author]; Snuderl, Matija [Author]; Abedalthagafi, Malak Sameer J. [Author]; Abdullaev, Zied [Author]; Monoranu, Camelia M. [Author]; Bergmann, Markus [Author]; Pekrun, Arnulf [Author]; Freyschlag, Christian [Author]; Aronica, Eleonora [Author]; Kramm, Christof M. [Author]; Hinz, Felix [Author]; Sievers, Philipp [Author]; Korshunov, Andrey [Author]; Kool, Marcel [Author]; Pfister, Stefan [Author]; [...]

    Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis

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    2021

    Published in: Acta neuropathologica ; 141(2021), 1, Seite 85-100

  19. Okonechnikov, Konstantin [Author]; Joshi, Piyush [Author]; Sepp, Mari [Author]; Leiss, Kevin [Author]; Sarropoulos, Ioannis [Author]; Murat, Florent [Author]; Sill, Martin [Author]; Beck, Pengbo [Author]; Chan, Kenneth Chun-Ho [Author]; Korshunov, Andrey [Author]; Sahm, Felix [Author]; Deng, Maximilian [Author]; Sturm, Dominik [Author]; DeSisto, John [Author]; Donson, Andrew M [Author]; Foreman, Nicholas K [Author]; Green, Adam L [Author]; Robinson, Giles [Author]; Orr, Brent A [Author]; Gao, Qingsong [Author]; Darrow, Emily [Author]; Hadley, Jennifer L [Author]; Northcott, Paul A [Author]; Gojo, Johannes [Author]; [...]

    Mapping pediatric brain tumors to their origins in the developing cerebellum

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    October 2023

    Published in: Neuro-Oncology ; 25(2023), 10 vom: Okt., Seite 1895-1909

  20. Bartl, Jasmin [Author]; Zanini, Marco [Author]; Nath, Soumav [Author]; Koumba, Idriss Mahoungou [Author]; Wolter, Marietta [Author]; Kuonen, François [Author]; Langini, Maike [Author]; Beez, Thomas [Author]; Munoz, Christopher [Author]; Pauck, David [Author]; Marquardt, Viktoria [Author]; Yu, Hua [Author]; Bernardi, Flavia [Author]; Souphron, Judith [Author]; Korsch, Mascha [Author]; Mölders, Christina [Author]; Berger, Daniel [Author]; Göbbels, Sarah [Author]; Meyer, Frauke-Dorothee [Author]; Scheffler, Björn [Author]; Rotblat, Barak [Author]; Diederichs, Sven [Author]; Ramaswamy, Vijay [Author]; Forget, Antoine [Author]; [...]

    The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors

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    Nature Publishing Group UK, 2022

    Published in: Nature Communications 13(1), 4061 (2022). doi:10.1038/s41467-022-31574-z