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Wüsthoff, Leonie [Author]; Laible, Mark [Author]; Kacprzyk, Łukasz Antoni [Author]; Wittig-Blaich, Stephanie Maritta [Author]; Tolstov, Yanis [Author]; Duensing, Stefan [Author]; Altevogt, Peter [Author]; Klauck, Sabine [Author]; Sültmann, Holger [Author]

TMPRSS2:ERG gene fusion variants induce TGF-β signaling and epithelial to mesenchymal transition in human prostate cancer cells

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6 March 2017

Published in: OncoTarget ; 8(2017), 15, Seite 25115-25130
Laible, Mark; Boonrod, Kajohn

Homemade Site Directed Mutagenesis of Whole Plasmids

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MyJove Corporation, 2009

Published in: Journal of Visualized Experiments (2009) 27
Laible, Mark; Boonrod, Kajohn

Homemade Site Directed Mutagenesis of Whole Plasmids

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MyJove Corporation, 2009

Published in: Journal of Visualized Experiments (2009) 27
Hartmann, Kerstin; Schlombs, Kornelia; Laible, Mark; Gürtler, Claudia; Schmidt, Marcus; Sahin, Ugur; Lehr, Hans-Anton

Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissue

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Springer Science and Business Media LLC, 2018

Published in: Diagnostic Pathology, 13 (2018) 1
Gürtler, Claudia; Laible, Mark; Schwabe, Wolfgang; Steinhäuser, Heike; Li, Xingmin; Liu, Shujin; Schlombs, Kornelia; Sahin, Ugur

Transferring a Quantitative Molecular Diagnostic Test to Multiple Real-Time Quantitative PCR Platforms

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Elsevier BV, 2018

Published in: The Journal of Molecular Diagnostics, 20 (2018) 4, Seite 398-414
Laible, Mark; Aulmann, Sebastian; Etzrodt, Alfred; Schmidt, Marcus; Crozier, Cheryl; Wirtz, Ralph; Bayani, Jane; Sahin, Ugur; Bartlett, John MS

Abstract P3-07-08: Comparison of MammaTyper® RT-qPCR based subtyping with simulated breast cancer prognostic signatures

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American Association for Cancer Research (AACR), 2020

Published in: Cancer Research, 80 (2020) 4_Supplement, Seite P3-07-08-P3-07-08
Laible, Mark; Hartmann, Kerstin; Gürtler, Claudia; Anzeneder, Tobias; Wirtz, Ralph; Weber, Stephan; Keller, Thomas; Sahin, Ugur; Rees, Martin; Ramaswamy, Annette

Impact of molecular subtypes on the prediction of distant recurrence in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) negative breast cancer upon five years of endocrine therapy

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Springer Science and Business Media LLC, 2019

Published in: BMC Cancer, 19 (2019) 1
Wirtz, Ralph M; Rau, Tilman; Laible, Mark; Schlombs, Kornelia; Lakis, Sotirios; Wachter, David; Sahin, Ugur; Hartmann, Arndt

Abstract P5-10-13: Low influence of tumor cell content on mRNA expression levels of ESR, PGR, HER2 and KI67 when performing the MammaTyper® RT-PCR kit

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American Association for Cancer Research (AACR), 2015

Published in: Cancer Research, 75 (2015) 9_Supplement, Seite P5-10-13-P5-10-13
Löbke, Christian; Laible, Mark; Rappl, Claudia; Ruschhaupt, Markus; Sahin, Özgür; Arlt, Dorit; Wiemann, Stefan; Poustka, Annemarie; Sültmann, Holger; Korf, Ulrike

Contact spotting of protein microarrays coupled with spike‐in of normalizer protein permits time‐resolved analysis of ERBB receptor signaling

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Wiley, 2008

Published in: PROTEOMICS, 8 (2008) 8, Seite 1586-1594
Caselli, Emanuele; Pelliccia, Cristina; Teti, Valeria; Bellezza, Guido; Mandarano, Martina; Ferri, Ivana; Hartmann, Kerstin; Laible, Mark; Sahin, Ugur; Varga, Zsuzsanna; Lupi, Chiara; Stracci, Fabrizio; Sidoni, Angelo

Looking for more reliable biomarkers in breast cancer: Comparison between routine methods and RT-qPCR

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Public Library of Science (PLoS), 2021

Published in: PLOS ONE, 16 (2021) 9, Seite e0255580
Saracchini, Silvana; Bassini, Anna; Marus, Wally; Corsetti, Serena; Specogna, Ilaria; Bertola, Manuela; Micheli, Elvia; Wirtz, Ralph M; Laible, Mark; Sahin, Ugur; Generali, Daniele; Sulfaro, Sandro

Abstract P1-10-23: Prediction of pathological complete response (pCR) upon neoadjuvant chemotherapy by MammaTyper® pCR score

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American Association for Cancer Research (AACR), 2020

Published in: Cancer Research, 80 (2020) 4_Supplement, Seite P1-10-23-P1-10-23
Sinn, Hans-Peter; Schneeweiss, Andreas; Keller, Marius; Schlombs, Kornelia; Laible, Mark; Seitz, Julia; Lakis, Sotirios; Veltrup, Elke; Altevogt, Peter; Eidt, Sebastian; Wirtz, Ralph M.; Marmé, Frederik

Comparison of immunohistochemistry with PCR for assessment of ER, PR, and Ki-67 and prediction of pathological complete response in breast cancer

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Springer Science and Business Media LLC, 2017

Published in: BMC Cancer, 17 (2017) 1
Breyer, Johannes; Wirtz, Ralph Markus; Otto, Wolfgang; Laible, Mark; Schlombs, Kornelia; Erben, Philipp; Kriegmair, Maximilian Christian; Stoehr, Robert; Eidt, Sebastian; Denzinger, Stefan; Burger, Maximilian; Hartmann, Arndt

Predictive value of molecular subtyping in NMIBC by RT-qPCR of ERBB2, ESR1, PGR and MKI67 from formalin fixed TUR biopsies

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Impact Journals, LLC, 2017

Published in: Oncotarget, 8 (2017) 40, Seite 67684-67695
Ratz, Leonie; Laible, Mark; Kacprzyk, Lukasz A.; Wittig-Blaich, Stephanie M.; Tolstov, Yanis; Duensing, Stefan; Altevogt, Peter; Klauck, Sabine M.; Sültmann, Holger

TMPRSS2:ERGgene fusion variants induce TGF-β signaling and epithelial to mesenchymal transition in human prostate cancer cells

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Impact Journals, LLC, 2017

Published in: Oncotarget, 8 (2017) 15, Seite 25115-25130
Breyer, Johannes; Wirtz, Ralph M.; Laible, Mark; Schlombs, Kornelia; Erben, Philipp; Kriegmair, Maximilian Christian; Stoehr, Robert; Eidt, Sebastian; Denzinger, Stefan; Burger, Maximilian; Hartmann, Arndt; Otto, Wolfgang

ESR1, ERBB2, and Ki67 mRNA expression predicts stage and grade of non-muscle-invasive bladder carcinoma (NMIBC)

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Springer Science and Business Media LLC, 2016

Published in: Virchows Archiv, 469 (2016) 5, Seite 547-552
Wirtz, Ralph M.; Scheffen, Iris; Marme, Frederik; Laible, Mark; Schlombs, Kornelia; Hake, Roland; Schumacher, Claudia; Schneeweiss, Andreas; Eidt, Sebastian; Sinn, Hans-Peter

Predictive value of ultra-high ESR1 mRNA expression in early breast cancer

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American Society of Clinical Oncology (ASCO), 2016

Published in: Journal of Clinical Oncology, 34 (2016) 15_suppl, Seite e12045-e12045
Laible, Mark; Schlombs, Kornelia; Kaiser, Katharina; Veltrup, Elke; Herlein, Stefanie; Lakis, Sotiris; Stöhr, Robert; Eidt, Sebastian; Hartmann, Arndt; Wirtz, Ralph M.; Sahin, Ugur

Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens

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Springer Science and Business Media LLC, 2016

Published in: BMC Cancer, 16 (2016) 1
Kacprzyk, Lukasz A.; Laible, Mark; Andrasiuk, Tatjana; Brase, Jan C.; Börno, Stefan T.; Fälth, Maria; Kuner, Ruprecht; Lehrach, Hans; Schweiger, Michal R.; Sültmann, Holger

ERG Induces Epigenetic Activation of Tudor Domain-Containing Protein 1 (TDRD1) in ERG Rearrangement-Positive Prostate Cancer

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Public Library of Science (PLoS), 2013

Published in: PLoS ONE, 8 (2013) 3, Seite e59976
Schettini, Francesco; Saracchini, Silvana; Bassini, Anna; Marus, Wally; Corsetti, Serena; Specogna, Ilaria; Bertola, Manuela; Micheli, Elvia; Wirtz, Ralph M.; Laible, Mark; Şahin, Uğur; Strina, Carla; Milani, Manuela; Aguggini, Sergio; Tancredi, Richard; Fiorio, Elena; Sulfaro, Sandro; Generali, Daniele

Prediction of response to neoadjuvant chemotherapy by MammaTyper® across breast cancer subtypes: A retrospective cross-sectional study

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Elsevier BV, 2024

Published in: The Breast, 76 (2024), Seite 103753
Simon, Adrian Georg; Lyu, Su Ir; Laible, Mark; Wöll, Stefan; Türeci, Özlem; Şahin, Uğur; Alakus, Hakan; Fahrig, Luca; Zander, Thomas; Buettner, Reinhard; Bruns, Christiane Josephine; Schroeder, Wolfgang; Gebauer, Florian; Quaas, Alexander

The tight junction protein claudin 6 is a potential target for patient-individualized treatment in esophageal and gastric adenocarcinoma and is associated with poor prognosis

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Springer Science and Business Media LLC, 2023

Published in: Journal of Translational Medicine, 21 (2023) 1

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