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  1. Salter, Claire G. [Author]; Cai, Yiying [Author]; Lo, Bernice [Author]; Helman, Guy [Author]; Taylor, Henry [Author]; McCartney, Amber [Author]; Leslie, Joseph S [Author]; Accogli, Andrea [Author]; Zara, Federico [Author]; Traverso, Monica [Author]; Fasham, James [Author]; Lees, Joshua A [Author]; Ferla, Matteo P [Author]; Chioza, Barry A [Author]; Wenger, Olivia [Author]; Scott, Ethan [Author]; Cross, Harold E [Author]; Crawford, Joanna [Author]; Warshawsky, Ilka [Author]; Keisling, Matthew [Author]; Agamanolis, Dimitris [Author]; Ward Melver, Catherine [Author]; Cox, Helen [Author]; Elawad, Mamoun [Author]; [...]

    Biallelic PI4KA variants cause neurological, intestinal and immunological disease

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    August 20, 2021

    Published in: Brain ; 144(2021), 12, Seite 3597-3610

  9. Karmakar, Parimal; Piotrowski, Jason; Brosh, Robert M.; Sommers, Joshua A.; Miller, Susan P. Lees; Cheng, Wen-Hsing; Snowden, Carey M.; Ramsden, Dale A.; Bohr, Vilhelm A.

    Werner Protein Is a Target of DNA-dependent Protein Kinase in Vivo and in Vitro, and Its Catalytic Activities Are Regulated by Phosphorylation

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    Elsevier BV, 2002

    Published in: Journal of Biological Chemistry

  11. Ghebreamlak, Selamawit; Stoian, Sebastian A.; Lees, Nicholas S.; Cronin, Bryan; Smith, Forrest; Ross, Matthew O.; Telser, Joshua; Hoffman, Brian M.; Duin, Evert C.

    The Active-Site [4Fe-4S] Cluster in the Isoprenoid Biosynthesis Enzyme IspH Adopts Unexpected Redox States during Ligand Binding and Catalysis

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    American Chemical Society (ACS), 2024

    Published in: Journal of the American Chemical Society

  15. Lenton, Timothy M.; Buxton, Joshua E.; Armstrong McKay, David I.; Abrams, Jesse F.; Boulton, Chris A.; Lees, Kirsten; Powell, Thomas W. R.; Boers, Niklas; Cunliffe, Andrew M.; Dakos, Vasilis

    A resilience sensing system for the biosphere

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    The Royal Society, 2022

    Published in: Philosophical Transactions of the Royal Society B: Biological Sciences

  16. Lees, Joshua A.; Zhang, Yixiao; Oh, Michael S.; Schauder, Curtis M.; Yu, Xiaoling; Baskin, Jeremy M.; Dobbs, Kerry; Notarangelo, Luigi D.; De Camilli, Pietro; Walz, Thomas; Reinisch, Karin M.

    Architecture of the human PI4KIIIα lipid kinase complex

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    Proceedings of the National Academy of Sciences, 2017

    Published in: Proceedings of the National Academy of Sciences

  17. Lees, Joshua A.; Zhang, Yixiao; Oh, Michael S.; Schauder, Curtis M.; Yu, Xiaoling; Baskin, Jeremy M.; Dobbs, Kerry; Notarangelo, Luigi D.; De Camilli, Pietro; Walz, Thomas; Reinisch, Karin M.

    Architecture of the human PI4KIIIα lipid kinase complex

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    National Academy of Sciences, 2017

    Published in: Proceedings of the National Academy of Sciences of the United States of America

  18. Lees, Joshua A.; Dias, João M.; Rajamohan, Francis; Fortin, Jean-Philippe; O’Connor, Rebecca; Kong, Jimmy X.; Hughes, Emily A. G.; Fisher, Ethan L.; Tuttle, Jamison B.; Lovett, Gabrielle; Kormos, Bethany L.; Unwalla, Rayomand J.; Zhang, Lei; Dechert Schmitt, Anne-Marie; Zhou, Dahui; Moran, Michael; Stevens, Kimberly A.; Fennell, Kimberly F.; Varghese, Alison E.; Maxwell, Andrew; Cote, Emmaline E.; Zhang, Yuan; Han, Seungil

    An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism

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    Springer Science and Business Media LLC, 2023

    Published in: Nature Communications

  19. Che, Ye; Gribenko, Alexey V.; Song, Xi; Handke, Luke D.; Efferen, Kari S.; Tompkins, Kristin; Kodali, Srinivas; Nunez, Lorna; Prasad, A. Krishna; Phelan, Lynn M.; Ammirati, Mark; Yu, Xiaodi; Lees, Joshua A.; Chen, Wei; Martinez, Lyndsey; Roopchand, Vidia; Han, Seungil; Qiu, Xiayang; DeVincenzo, John P.; Jansen, Kathrin U.; Dormitzer, Philip R.; Swanson, Kena A.

    Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine

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    American Association for the Advancement of Science (AAAS), 2023

    Published in: Science Translational Medicine

  20. Shao, Wenlin; Mishina, Yuji M.; Feng, Yun; Caponigro, Giordano; Cooke, Vesselina G.; Rivera, Stacy; Wang, Yingyun; Shen, Fang; Korn, Joshua M.; Mathews Griner, Lesley A.; Nishiguchi, Gisele; Rico, Alice; Tellew, John; Haling, Jacob R.; Aversa, Robert; Polyakov, Valery; Zang, Richard; Hekmat-Nejad, Mohammad; Amiri, Payman; Singh, Mallika; Keen, Nicholas; Dillon, Michael P.; Lees, Emma; Ramurthy, Savithri; [...]

    Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF

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    American Association for Cancer Research (AACR), 2018

    Published in: Cancer Research