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Linares, Laetitia K. [Author]; Hengstermann, Arnd [Author]; Ciechanover, Aaron J. [Author]; Müller, Stefan [Author]; Scheffner, Martin [Author]

HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53

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Konstanz: Bibliothek der Universität Konstanz, 2003
Hengstermann, Arnd [Author]; Linares, Laetitia K. [Author]; Ciechanover, Aaron J. [Author]; Whitaker, Noel J. [Author]; Scheffner, Martin [Author]

Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells

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Konstanz: Bibliothek der Universität Konstanz, 2001
Linares, Laëtitia K; Scheffner, Martin

The ubiquitin–protein ligase activity of Hdm2 is inhibited by nucleic acids

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Wiley, 2003

Published in: FEBS Letters, 554 (2003) 1-2, Seite 73-76
Arena, Giuseppe; Riscal, Romain; Linares, Laetitia K.; Le Cam, Laurent

MDM2 controls gene expression independently of p53 in both normal and cancer cells

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Springer Science and Business Media LLC, 2018

Published in: Cell Death & Differentiation, 25 (2018) 9, Seite 1533-1535
Riscal, Romain; Le Cam, Laurent; Linares, Laetitia K.

Chromatin-bound MDM2, a new player in metabolism

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Informa UK Limited, 2016

Published in: Molecular & Cellular Oncology, 3 (2016) 5, Seite e1210560
Lahalle, Airelle; Lacroix, Matthieu; De Blasio, Carlo; Cissé, Madi Y.; Linares, Laetitia K.; Le Cam, Laurent

The p53 Pathway and Metabolism: The Tree That Hides the Forest

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MDPI AG, 2021

Published in: Cancers, 13 (2021) 1, Seite 133
Legube, Gaëlle; Linares, Laetitia K.; Tyteca, Sandrine; Caron, Cécile; Scheffner, Martin; Chevillard-Briet, Martine; Trouche, Didier

Role of the Histone Acetyl Transferase Tip60 in the p53 Pathway

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Elsevier BV, 2004

Published in: Journal of Biological Chemistry, 279 (2004) 43, Seite 44825-44833
Linares, Laëtitia K.; Hengstermann, Arnd; Ciechanover, Aaron; Müller, Stefan; Scheffner, Martin

HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53

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Proceedings of the National Academy of Sciences, 2003

Published in: Proceedings of the National Academy of Sciences, 100 (2003) 21, Seite 12009-12014
Linares, Laëtitia K.; Hengstermann, Arnd; Ciechanover, Aaron; Müller, Stefan; Scheffner, Martin

HdmX Stimulates Hdm2-Mediated Ubiquitination and Degradation of p53

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National Academy of Sciences, 2003

Published in: Proceedings of the National Academy of Sciences of the United States of America, 100 (2003) 21, Seite 12009-12014
Hengstermann, Arnd; Linares, Laetitia K.; Ciechanover, Aaron; Whitaker, Noel J.; Scheffner, Martin

Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells

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Proceedings of the National Academy of Sciences, 2001

Published in: Proceedings of the National Academy of Sciences, 98 (2001) 3, Seite 1218-1223
Hengstermann, Arnd; Linares, Laetitia K.; Ciechanover, Aaron; Whitaker, Noel J.; Scheffner, Martin

Complete Switch from Mdm2 to Human Papillomavirus E6-Mediated Degradation of p53 in Cervical Cancer Cells

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National Academy of Sciences, 2001

Published in: Proceedings of the National Academy of Sciences of the United States of America, 98 (2001) 3, Seite 1218-1223
Andrique, Caroline; Morardet, Laetitia; Linares, Laetitia K.; Cissé, Madi Y.; Merle, Candice; Chibon, Frédéric; Provot, Sylvain; Haÿ, Eric; Ea, Hang-Korng; Cohen-Solal, Martine; Modrowski, Dominique

Calpain-6 controls the fate of sarcoma stem cells by promoting autophagy and preventing senescence

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American Society for Clinical Investigation, 2018

Published in: JCI Insight, 3 (2018) 17
Jacquier, Valentin; Gitenay, Delphine; Fritsch, Samuel; Bonnet, Sandrine; Győrffy, Balázs; Jalaguier, Stéphan; Linares, Laetitia K.; Cavaillès, Vincent; Teyssier, Catherine

RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53

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Springer Science and Business Media LLC, 2022

Published in: Cellular and Molecular Life Sciences, 79 (2022) 5
Heuillet, Maud; Millard, Pierre; Cissé, Madi Y.; Linares, Laetitia K.; Létisse, Fabien; Manié, Serge; Le Cam, Laurent; Portais, Jean-Charles; Bellvert, Floriant

Simultaneous Measurement of Metabolite Concentration and Isotope Incorporation by Mass Spectrometry

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American Chemical Society (ACS), 2020

Published in: Analytical Chemistry, 92 (2020) 8, Seite 5890-5896
Champagne, Julien; Linares, Laetitia K.; Maurel, Benjamin; Zampieri, Alexandre; Moreno, Maeva; Fuentes, Ivanna; Dubois, Emeric; Severac, Dany; Decorsière, Adrien; Bienvenu, Frédéric

TAG-RNAi overcomes off-target effects in cancer models

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Springer Science and Business Media LLC, 2020

Published in: Oncogene, 39 (2020) 4, Seite 935-945
Linares, Laëtitia K.; Kiernan, Rosemary; Triboulet, Robinson; Chable-Bessia, Christine; Latreille, Daniel; Cuvier, Olivier; Lacroix, Matthieu; Le Cam, Laurent; Coux, Olivier; Benkirane, Monsef

Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2

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Springer Science and Business Media LLC, 2007

Published in: Nature Cell Biology, 9 (2007) 3, Seite 331-338
Lassot, Irina; Latreille, Daniel; Rousset, Emilie; Sourisseau, Marion; Linares, Laetitia K.; Chable-Bessia, Christine; Coux, Olivier; Benkirane, Monsef; Kiernan, Rosemary E.

The Proteasome Regulates HIV-1 Transcription by Both Proteolytic and Nonproteolytic Mechanisms

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Elsevier BV, 2007

Published in: Molecular Cell, 25 (2007) 3, Seite 369-383
Le Cam, Laurent; Linares, Laëtitia K.; Paul, Conception; Julien, Eric; Lacroix, Matthieu; Hatchi, Elodie; Triboulet, Robinson; Bossis, Guillaume; Shmueli, Ayelet; Rodriguez, Manuel S.; Coux, Olivier; Sardet, Claude

E4F1 Is an Atypical Ubiquitin Ligase that Modulates p53 Effector Functions Independently of Degradation

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Elsevier BV, 2006

Published in: Cell, 127 (2006) 4, Seite 775-788
Marzi, Laetitia; Combes, Eve; VIE, Nadia; Tosi, Diego; Ayrolles-Torro, Adeline; Larbouret, Christel; Denis, Vincent; Linares, Laetitia K.; Montagut, Clara; Iglesias, Mar; Martineau, Pierre; Lam, Eric W-F; Del Rio, Maguy; Gongora, Céline

Abstract B16: Cetuximab activates Foxo3a via the MAPK p38 to induce apoptosis and reduce cell proliferation in colorectal cancer cells

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American Association for Cancer Research (AACR), 2015

Published in: Molecular Cancer Therapeutics, 14 (2015) 12_Supplement_2, Seite B16-B16
Bach, Anne-Sophie; Derocq, Danielle; Laurent-Matha, Valérie; Montcourrier, Philippe; Sebti, Salwa; Orsetti, Béatrice; Theillet, Charles; Gongora, Céline; Pattingre, Sophie; Ibing, Eva; Roger, Pascal; Linares, Laetitia K.; Reinheckel, Thomas; Meurice, Guillaume; Kaiser, Frank J.; Gespach, Christian; Liaudet-Coopman, Emmanuelle

Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells

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Impact Journals, LLC, 2015

Published in: Oncotarget, 6 (2015) 29, Seite 28084-28103

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