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Friedrich, Felix [Author]; Wilding, Brendan R. [Author]; Reischmann, Silke [Author]; Crocini, Claudia [Author]; Lang, Patrick [Author]; Charron, Philippe [Author]; Müller, Oliver J. [Author]; McGrath, Meagan J. [Author]; Vollert, Ingra [Author]; Hansen, Arne [Author]; Linke, Wolfgang A. [Author]; Hengstenberg, Christian [Author]; Bonne, Gisèle [Author]; Morner, Stellan [Author]; Wichter, Thomas [Author]; Madeira, Hugo [Author]; Arbustini, Eloisa [Author]; Eschenhagen, Thomas [Author]; Mitchell, Christina A. [Author]; Isnard, Richard [Author]; Carrier, Lucie [Author]

Evidence for FHL1 as a novel disease gene for isolated hypertrophic cardiomyopathy

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April 20, 2012

Published in: Human molecular genetics ; 21(2012), 14, Seite 3237-3254
Rodgers, Samuel J.; Jones, Emily I.; Mitchell, Christina A.; McGrath, Meagan J.

Sequential conversion of PtdIns3P to PtdIns(3,5)P 2 via endosome maturation couples nutrient signaling to lysosome reformation and basal autophagy

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Informa UK Limited, 2023

Published in: Autophagy, 19 (2023) 4, Seite 1365-1367
Eramo, Matthew J.; Gurung, Rajendra; Mitchell, Christina A.; McGrath, Meagan J.

Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P2 is required for autophagic lysosome reformation and protection from skeletal muscle disease

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Informa UK Limited, 2021

Published in: Autophagy, 17 (2021) 5, Seite 1287-1289
Wilding, Brendan R.; McGrath, Meagan J.; Bonne, Gisèle; Mitchell, Christina A.

FHL1 mutations that cause clinically distinct human myopathies form protein aggregates and impair myoblast differentiation

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The Company of Biologists, 2014

Published in: Journal of Cell Science (2014)
McGrath, Meagan J.; Mitchell, Christina A.; Coghill, Imogen D.; Robinson, Paul A.; Brown, Susan

Skeletal muscle LIM protein 1 (SLIM1/FHL1) induces α5β1-integrin-dependent myocyte elongation

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American Physiological Society, 2003

Published in: American Journal of Physiology-Cell Physiology, 285 (2003) 6, Seite C1513-C1526
Brown, Susan; Coghill, Imogen D.; McGrath, Meagan J.; Robinson, Paul A.

Role of LIM Domains in Mediating Signaling Protein Interactions

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Wiley, 2001

Published in: IUBMB Life, 51 (2001) 6, Seite 359-364
Nanayakkara, Randini; Gurung, Rajendra; Rodgers, Samuel J.; Eramo, Matthew J.; Ramm, Georg; Mitchell, Christina A.; McGrath, Meagan J.

Autophagic lysosome reformation in health and disease

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Informa UK Limited, 2023

Published in: Autophagy, 19 (2023) 5, Seite 1378-1395
Cottle, Denny L.; McGrath, Meagan J.; Cowling, Belinda S.; Coghill, Imogen D.; Brown, Susan; Mitchell, Christina A.

FHL3 binds MyoD and negatively regulates myotube formation

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The Company of Biologists, 2007

Published in: Journal of Cell Science, 120 (2007) 8, Seite 1423-1435
Robinson, Paul A.; Brown, Susan; McGrath, Meagan J.; Coghill, Imogen D.; Gurung, Rajendra; Mitchell, Christina A.

Skeletal muscle LIM protein 1 regulates integrin-mediated myoblast adhesion, spreading, and migration

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American Physiological Society, 2003

Published in: American Journal of Physiology-Cell Physiology, 284 (2003) 3, Seite C681-C695
Brown, Susan; McGrath, Meagan J.; Ooms, Lisa M.; Gurung, Rajendra; Maimone, Margaret M.; Mitchell, Christina A.

Characterization of Two Isoforms of the Skeletal Muscle LIM Protein 1, SLIM1

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Elsevier BV, 1999

Published in: Journal of Biological Chemistry, 274 (1999) 38, Seite 27083-27091
McKaige, Emily A; Lee, Clara; Calcinotto, Vanessa; Giri, Saveen; Crawford, Simon; McGrath, Meagan J; Ramm, Georg; Bryson-Richardson, Robert J

Mitochondrial abnormalities contribute to muscle weakness in a Dnajb6 deficient zebrafish model

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Oxford University Press (OUP), 2024

Published in: Human Molecular Genetics, 33 (2024) 14, Seite 1195-1206
Coghill, Imogen D.; Brown, Susan; Cottle, Denny L.; McGrath, Meagan J.; Robinson, Paul A.; Nandurkar, Harshal H.; Dyson, Jennifer M.; Mitchell, Christina A.

FHL3 Is an Actin-binding Protein That Regulates α-Actinin-mediated Actin Bundling

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Elsevier BV, 2003

Published in: Journal of Biological Chemistry, 278 (2003) 26, Seite 24139-24152
Gurung, Rajendra; Tan, April; Ooms, Lisa M.; McGrath, Meagan J.; Huysmans, Richard D.; Munday, Adam D.; Prescott, Mark; Whisstock, James C.; Mitchell, Christina A.

Identification of a Novel Domain in Two Mammalian Inositol-polyphosphate 5-Phosphatases That Mediates Membrane Ruffle Localization

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Elsevier BV, 2003

Published in: Journal of Biological Chemistry, 278 (2003) 13, Seite 11376-11385
Brown, Susan; Biben, Christine; Ooms, Lisa M.; Maimone, Margaret; McGrath, Meagan J.; Gurung, Rajendra; Harvey, Richard P.; Mitchell, Christina A.

The Cardiac Expression of Striated Muscle LIM Protein 1 (SLIM1) is Restricted to the Outflow Tract of the Developing Heart

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Elsevier BV, 1999

Published in: Journal of Molecular and Cellular Cardiology, 31 (1999) 4, Seite 837-843
McGrath, Meagan J.; Eramo, Matthew J.; Gurung, Rajendra; Sriratana, Absorn; Gehrig, Stefan M.; Lynch, Gordon S.; Lourdes, Sonia Raveena; Koentgen, Frank; Feeney, Sandra J.; Lazarou, Michael; McLean, Catriona A.; Mitchell, Christina A.

Defective lysosome reformation during autophagy causes skeletal muscle disease

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American Society for Clinical Investigation, 2021

Published in: Journal of Clinical Investigation, 131 (2021) 1
Feeney, Sandra J.; McGrath, Meagan J.; Sriratana, Absorn; Gehrig, Stefan M.; Lynch, Gordon S.; D’Arcy, Colleen E.; Price, John T.; McLean, Catriona A.; Tupler, Rossella; Mitchell, Christina A.

FHL1 Reduces Dystrophy in Transgenic Mice Overexpressing FSHD Muscular Dystrophy Region Gene 1 (FRG1)

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Public Library of Science (PLoS), 2015

Published in: PLOS ONE, 10 (2015) 2, Seite e0117665
D'Arcy, Colleen E.; Feeney, Sandra J.; McLean, Catriona A.; Gehrig, Stefan M.; Lynch, Gordon S.; Smith, Jaclyn E.; Cowling, Belinda S.; Mitchell, Christina A.; McGrath, Meagan J.

Identification of FHL1 as a therapeutic target for Duchenne muscular dystrophy

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Oxford University Press (OUP), 2014

Published in: Human Molecular Genetics, 23 (2014) 3, Seite 618-636
Rodgers, Samuel J; Jones, Emily I; Arumugam, Senthil; Hamila, Sabryn A; Danne, Jill; Gurung, Rajendra; Eramo, Matthew J; Nanayakkara, Randini; Ramm, Georg; McGrath, Meagan J; Mitchell, Christina A

Endosome maturation links PI3Kα signaling to lysosome repopulation during basal autophagy

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Springer Science and Business Media LLC, 2022

Published in: The EMBO Journal, 41 (2022) 19
Cowling, Belinda S.; McGrath, Meagan J.; Nguyen, Mai-Anh; Cottle, Denny L.; Kee, Anthony J.; Brown, Susan; Schessl, Joachim; Zou, Yaqun; Joya, Josephine; Bönnemann, Carsten G.; Hardeman, Edna C.; Mitchell, Christina A.

Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy

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Rockefeller University Press, 2008

Published in: The Journal of Cell Biology, 183 (2008) 6, Seite 1033-1048
Conduit, Sarah E; Davies, Elizabeth M; Ooms, Lisa M; Gurung, Rajendra; McGrath, Meagan J; Hakim, Sandra; Cottle, Denny L; Smyth, Ian M; Dyson, Jennifer M; Mitchell, Christina A

AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease

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Oxford University Press (OUP), 2019

Published in: Human Molecular Genetics (2019)

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