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Engelhardt, Monika [Author]; Shoumariyeh, Khalid [Author]; Rösner, Amelie [Author]; Ihorst, Gabriele [Author]; Biavasco, Francesca [Author]; Meckel, Katharina Elisabeth [Author]; Metzler, Ivana von [Author]; Treurich, Sebastian [Author]; Hebart, Holger [Author]; Grube, Matthias [Author]; Kull, Miriam [Author]; Bassermann, Florian [Author]; Schäfer-Eckart, Kerstin [Author]; Hoferer, Anette [Author]; Einsele, Hermann [Author]; Rasche, Leo [Author]; Wäsch, Ralph [Author]

Clinical characteristics and outcome of multiple myeloma patients with concomitant COVID-19 at Comprehensive Cancer Centers in Germany

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Pavia: Ferrata Storti Foundation (Haematologica), 2020

Published in: Haematologica ; 105, 12 (2020), 2872-2878
Ullrich, Evelyn; Vogler, Meike; von Metzler, Ivana

Mitochondrial apoptosis: facilitator of NK cell-mediated immunotherapy

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Springer Science and Business Media LLC, 2022

Published in: Signal Transduction and Targeted Therapy, 7 (2022) 1
Kaiser, Martin F.; Heider, Ulrike; Mieth, Maren; Zang, Chuanbing; von Metzler, Ivana; Sezer, Orhan

The proteasome inhibitor bortezomib stimulates osteoblastic differentiation of human osteoblast precursors via upregulation of vitamin D receptor signalling

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Wiley, 2013

Published in: European Journal of Haematology, 90 (2013) 4, Seite 263-272
Kaiser, Martin F.; Heider, Ulrike; Mieth, Maren; Zustin, Jozef; Kuehnl, Andrea; von Metzler, Ivana; Sezer, Orhan

Induction of CXCL1 in Osteoblasts by Myeloma Cells Promotes Migration of Osteoclast Precursors

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American Society of Hematology, 2012

Published in: Blood, 120 (2012) 21, Seite 441-441
Heider, Ulrike; Rademacher, Jessica; Kaiser, Martin; von Metzler, Ivana; Marquardt, Karin; Sezer, Orhan

Decrease in CD4+ T Cells in Multiple Myeloma Patients Receiving Bortezomib

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American Society of Hematology, 2009

Published in: Blood, 114 (2009) 22, Seite 3865-3865
Hecht, Monica; Heider, Ulrike; Kaiser, Martin; Von Metzler, Ivana; Sterz, Jan; Sezer, Orhan

Osteoblasts promote migration and invasion of myeloma cells through upregulation of matrix metalloproteinases, urokinase plasminogen activator, hepatocyte growth factor and activation of p38 MAPK

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Wiley, 2007

Published in: British Journal of Haematology, 138 (2007) 4, Seite 446-458
Seibert, Marcel; Koschade, Sebastian E.; Stolp, Verena; Häupl, Björn; Wempe, Frank; Serve, Hubert; Kurrle, Nina; Schnütgen, Frank; von Metzler, Ivana

The MYC-Regulated RNA-Binding Proteins hnRNPC and LARP1 Are Drivers of Multiple Myeloma Cell Growth and Disease Progression and Negatively Predict Patient Survival

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MDPI AG, 2023

Published in: Cancers, 15 (2023) 23, Seite 5508
Enßle, Julius C.; Wolf, Sebastian; von Metzler, Ivana; Weber, Sarah; Bialleck, Heike; Seifried, Erhard; Serve, Hubert; Scheich, Sebastian; Steffen, Björn

High CD34 positive stem cell dosage improves thrombocyte recovery in obese myeloma patients undergoing autologous stem cell transplantation

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Informa UK Limited, 2021

Published in: Leukemia & Lymphoma, 62 (2021) 13, Seite 3283-3287
Tognarelli, Sara; Wirsching, Sebastian; von Metzler, Ivana; Rais, Bushra; Jacobs, Benedikt; Serve, Hubert; Bader, Peter; Ullrich, Evelyn

Enhancing the Activation and Releasing the Brakes: A Double Hit Strategy to Improve NK Cell Cytotoxicity Against Multiple Myeloma

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Frontiers Media SA, 2018

Published in: Frontiers in Immunology, 9 (2018)
von Metzler, Ivana; Krebbel, Holger; Kuckelkorn, Ulrike; Heider, Ulrike; Jakob, Christian; Kaiser, Martin; Fleissner, Claudia; Terpos, Evangelos; Sezer, Orhan

Curcumin diminishes human osteoclastogenesis by inhibition of the signalosome-associated IκB kinase

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Springer Science and Business Media LLC, 2009

Published in: Journal of Cancer Research and Clinical Oncology, 135 (2009) 2, Seite 173-179
Heider, Ulrike; Rademacher, Jessica; Lamottke, Britta; Mieth, Maren; Moebs, Markus; Von Metzler, Ivana; Assaf, Chalid; Sezer, Orhan

Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in cutaneous T cell lymphoma

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Wiley, 2009

Published in: European Journal of Haematology, 82 (2009) 6, Seite 440-449
Sterz, Jan; Metzler, Ivana von; Hahne, Jens-Claus; Lamottke, Britta; Rademacher, Jessica; Heider, Ulrike; Terpos, Evangelos; Sezer, Orhan

The potential of proteasome inhibitors in cancer therapy

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Informa Healthcare, 2008

Published in: Expert Opinion on Investigational Drugs, 17 (2008) 6, Seite 879-895
Enssle, Julius; Brinkschmidt, Tonio; Dürrwald, Ralf; Wolf, Sebastian; Zurmeyer, David; Steffen, Björn; Ullrich, Evelyn; Serve, Hubert; Oellerich, Thomas; von Metzler, Ivana

Immune Responses after One Versus Two Influenza A/B Vaccinations in Patients with Multiple Myeloma

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American Society of Hematology, 2023

Published in: Blood, 142 (2023) Supplement 1, Seite 4737-4737
von Metzler, Ivana; Campe, Julia; Huenecke, Sabine; Raab, Marc S.; Goldschmidt, Hartmut; Schubert, Ralf; Rabenau, Holger F.; Ciesek, Sandra; Serve, Hubert; Ullrich, Evelyn

COVID-19 in multiple-myeloma patients: cellular and humoral immunity against SARS-CoV-2 in a short- and long-term view

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Springer Science and Business Media LLC, 2022

Published in: Journal of Molecular Medicine, 100 (2022) 3, Seite 463-470
Bexte, Tobias; Alzubi, Jamal; Reindl, Lisa Marie; Wendel, Philipp; Schubert, Ralf; Salzmann-Manrique, Emilia; von Metzler, Ivana; Cathomen, Toni; Ullrich, Evelyn

CRISPR-Cas9 based gene editing of the immune checkpoint NKG2A enhances NK cell mediated cytotoxicity against multiple myeloma

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Informa UK Limited, 2022

Published in: OncoImmunology, 11 (2022) 1
Lamottke, Britta; Kaiser, Martin; Mieth, Maren; Heider, Ulrike; Gao, Zhenhai; Nikolova, Zariana; Jensen, Michael R.; Sterz, Jan; von Metzler, Ivana; Sezer, Orhan

The novel, orally bioavailable HSP90 inhibitor NVP‐HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases

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Wiley, 2012

Published in: European Journal of Haematology, 88 (2012) 5, Seite 406-415
Sterz, Jan; Jakob, Christian; Kuckelkorn, Ulrike; Heider, Ulrike; Mieth, Maren; Kleeberg, Lorenz; Kaiser, Martin; Kloetzel, Peter‐M.; Sezer, Orhan; Von Metzler, Ivana

BSc2118 is a novel proteasome inhibitor with activity against multiple myeloma

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Wiley, 2010

Published in: European Journal of Haematology, 85 (2010) 2, Seite 99-107
Kaiser, Martin; Lamottke, Britta; Mieth, Maren; Jensen, Michael R.; Quadt, Cornelia; Garcia‐Echeverria, Carlos; Atadja, Peter; Heider, Ulrike; Von Metzler, Ivana; Türkmen, Seval; Sezer, Orhan

Synergistic action of the novel HSP90 inhibitor NVP‐AUY922 with histone deacetylase inhibitors, melphalan, or doxorubicin in multiple myeloma

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Wiley, 2010

Published in: European Journal of Haematology, 84 (2010) 4, Seite 337-344
Heider, Ulrike; Metzler, Ivana von; Kaiser, Martin; Rosche, Marleen; Sterz, Jan; Rötzer, Susanne; Rademacher, Jessica; Jakob, Christian; Fleissner, Claudia; Kuckelkorn, Ulrike; Kloetzel, Peter‐Michael; Sezer, Orhan

Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma

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Wiley, 2008

Published in: European Journal of Haematology, 80 (2008) 2, Seite 133-142
Jakob, Christian; Sterz, Jan; von Metzler, Ivana; Kuckelkorn, Ulrike; Braun, Hannes A.; Rötzer, Susanne; Kaiser, Martin; Heider, Ulrike; Rademacher, Jessica; Kloetzel, Peter M.; Sezer, Orhan

The Proteasome Inhibitor BSc2118 Causes Growth Inhibition, Cell Cycle Arrest and Cyclin D1 Degradation in Mantle Cell Lymphoma Cell Lines

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American Society of Hematology, 2007

Published in: Blood, 110 (2007) 11, Seite 1401-1401

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