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Lauinger, Manuel [Author]; Christen, Daniel [Author]; Klar, Rhena F. U [Author]; Roubaty, Carole [Author]; Heilig, Christoph E. [Author]; Stumpe, Michael [Author]; Knox, Jennifer J. [Author]; Radulovich, Nikolina [Author]; Tamblyn, Laura [Author]; Xie, Irene Y. [Author]; Horak, Peter [Author]; Forschner, Andrea [Author]; Bitzer, Michael [Author]; Wittel, Uwe A. [Author]; Boerries, Melanie [Author]; Ball, Claudia R. [Author]; Heining, Christoph [Author]; Glimm, Hanno [Author]; Fröhlich, Martina [Author]; Hübschmann, Daniel [Author]; Gallinger, Steven [Author]; Fritsch, Ralph [Author]; Fröhling, Stefan [Author]; O’Kane, Grainne M. [Author]; [...]

BRAFΔβ3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability

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https://www.science.org/doi/10.1126/sciadv.ade7486

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2023

Published in: Science advances ; 9(2023), 35, Artikel-ID eade7486, Seite 1-22
Grünwald, Barbara T. [Author]; Devisme, Antoine [Author]; Geoffroy, Andrieux [Author]; Vyas, Foram [Author]; Aliar, Kazeera [Author]; McCloskey, Curtis W. [Author]; Macklin, Andrew [Author]; Jang, Gun Ho [Author]; Denroche, Robert [Author]; Romero, Joan M. [Author]; Bavi, Prashant [Author]; Bronsert, Peter [Author]; Notta, Faiyaz [Author]; O’Kane, Grainne [Author]; Wilson, Julie [Author]; Knox, Jennifer [Author]; Tamblyn, Laura [Author]; Udaskin, Molly [Author]; Radulovich, Nikolina [Author]; Fischer, Sandra E. [Author]; Börries, Melanie [Author]; Gallinger, Steven [Author]; Kislinger, Thomas [Author]; Khokha, Rama [Author]

Spatially confined sub-tumor microenvironments in pancreatic cancer

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New York, NY: Elsevier, 2021

Published in: Cell ; 184, 22 (2021), 5577-5592.e18
Fitzpatrick, Orla M.; O’Kane, Grainne M.

Determinants of gemcitabine response in pancreatic cancer: are we there?

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AME Publishing Company, 2023

Published in: Journal of Gastrointestinal Oncology
O'Kane, Grainne M.; Lowery, Maeve A.

Moving the Needle on Precision Medicine in Pancreatic Cancer

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American Society of Clinical Oncology (ASCO), 2022

Published in: Journal of Clinical Oncology
O’Kane, Grainne M.; Leighl, Natasha B.

Systemic Therapy of Lung Cancer CNS Metastases Using Molecularly Targeted Agents and Immune Checkpoint Inhibitors

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Springer Science and Business Media LLC, 2018

Published in: CNS Drugs
O’Kane, Grainne M.; Leighl, Natasha B.

Are immune checkpoint blockade monoclonal antibodies active against CNS metastases from NSCLC?—current evidence and future perspectives

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AME Publishing Company, 2016

Published in: Translational Lung Cancer Research
Choi, Woo Jin; Sapisochin, Gonzalo; O’Kane, Grainne M.

ASO Author Reflections: Incorporating Circulating Tumor DNA in Perioperative Management of Intrahepatic Cholangiocarcinoma

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Springer Science and Business Media LLC, 2023

Published in: Annals of Surgical Oncology
O’Kane, Grainne M.; Ladak, Farah; Gallinger, Steven

Advances in the management of pancreatic ductal adenocarcinoma

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CMA Impact Inc., 2021

Published in: Canadian Medical Association Journal
O’Kane, Grainne M.; Ladak, Farah; Gallinger, Steven

Avancées dans la prise en charge de l’adénocarcinome canalaire pancréatique

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CMA Joule Inc., 2021

Published in: Canadian Medical Association Journal
Linehan, Anna; O’Reilly, Mary; McDermott, Ray; O’Kane, Grainne M.

Targeting KRAS mutations in pancreatic cancer: opportunities for future strategies

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Frontiers Media SA, 2024

Published in: Frontiers in Medicine
Choi, Woo Jin; Ivanics, Tommy; Gravely, Annabel; Gallinger, Steven; Sapisochin, Gonzalo; O’Kane, Grainne M.

ASO Visual Abstract: Optimizing Circulating Tumor DNA Use in the Perioperative Setting for Intrahepatic Cholangiocarcinoma—Diagnosis, Screening, Minimal Residual Disease Detection, and Treatment Response Monitoring

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Springer Science and Business Media LLC, 2023

Published in: Annals of Surgical Oncology
Choi, Woo Jin; Ivanics, Tommy; Gravely, Annabel; Gallinger, Steven; Sapisochin, Gonzalo; O’Kane, Grainne M.

Optimizing Circulating Tumour DNA Use in the Perioperative Setting for Intrahepatic Cholangiocarcinoma: Diagnosis, Screening, Minimal Residual Disease Detection and Treatment Response Monitoring

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Springer Science and Business Media LLC, 2023

Published in: Annals of Surgical Oncology
Tsang, Erica S.; O'Kane, Grainne M.; Knox, Jennifer J.; Chen, Eric X

A phase II study of olaparib and durvalumab in patients with IDH-mutated cholangiocarcinoma

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American Society of Clinical Oncology (ASCO), 2023

Published in: Journal of Clinical Oncology
O’Kane, Grainne M.; Labbé, Catherine; Doherty, Mark K.; Young, Kelvin; Albaba, Hamzeh; Leighl, Natasha B.

Monitoring and Management of Immune-Related Adverse Events Associated With Programmed Cell Death Protein-1 Axis Inhibitors in Lung Cancer

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Oxford University Press (OUP), 2017

Published in: The Oncologist
Barnes, Tristan A.; O’Kane, Grainne M.; Vincent, Mark David; Leighl, Natasha B.

Third-Generation Tyrosine Kinase Inhibitors Targeting Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer

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Frontiers Media SA, 2017

Published in: Frontiers in Oncology
Perera, Sheron; Jang, Gun Ho; Grant, Robert; Notta, Faiyaz; Grunwald, Barbara; Gallinger, Steven; Knox, Jennifer J.; O'Kane, Grainne M.

hENT1 as a Predictive Biomarker in PDAC—Response

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American Association for Cancer Research (AACR), 2023

Published in: Clinical Cancer Research
Chen, Eric Xueyu; O'Kane, Grainne M.; Mason, Warren P.; Knox, Jennifer J.; Abdul Razak, Albiruni Ryan; Zadeh, Gelareh

Phase II basket trial of olaparib and durvalumab in patients (pts) with isocitrate dehydrogenase (IDH) mutated solid tumors

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American Society of Clinical Oncology (ASCO), 2020

Published in: Journal of Clinical Oncology
Walsh, Elaine; O'Kane, Grainne; Cadoo, Karen Anne; Graham, Donna M.; Korpanty, Grzegorz; Power, Derek Gerard; Carney, Desmond

Cancer in pregnancy: To treat or not?

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American Society of Clinical Oncology (ASCO), 2013

Published in: Journal of Clinical Oncology
Salinas-Miranda, Emmanuel; Khalvati, Farzad; Namdar, Kashayar; Deniffel, Dominik; Dong, Xin; Abbas, Engy; Wilson, Julie M.; O’Kane, Grainne M.; Knox, Jennifer; Gallinger, Steven; Haider, Masoom A.

Validation of Prognostic Radiomic Features From Resectable Pancreatic Ductal Adenocarcinoma in Patients With Advanced Disease Undergoing Chemotherapy

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SAGE Publications, 2021

Published in: Canadian Association of Radiologists Journal
Duan, Kai; Jang, Gun-Ho; Grant, Robert C.; Wilson, Julie M.; Notta, Faiyaz; O’Kane, Grainne M.; Knox, Jennifer J.; Gallinger, Steven; Fischer, Sandra

The value of GATA6 immunohistochemistry and computer-assisted diagnosis to predict clinical outcome in advanced pancreatic cancer

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Springer Science and Business Media LLC, 2021

Published in: Scientific Reports

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