Skip to contents Rüdesheim, Simeon Matthias [Author] ; Lehr, Thorsten [Degree supervisor] Predicting the effect of drug-gene and drug-drug-gene interactions on the pharmacokinetics of CYP2D6 substrates : leveraging the activity score system in physiologically based pharmacokinetic modeling Books View online Schließen > Access https://d-nb.info/132252954X/34 kostenfrei Show more show less Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Saarbrücken: Saarländische Universitäts- und Landesbibliothek, 2023 Rüdesheim, Simeon Matthias [Author] ; Lehr, Thorsten [Degree supervisor]; Meyer, Markus Robert [Degree supervisor]; Schwab, Matthias [Degree supervisor] Predicting the effect of drug-gene and drug-drug-gene interactions on the pharmacokinetics of CYP2D6 substrates : leveraging the activity score system in physiologically based pharmacokinetic modeling Books View online Schließen > Access Full access (via DOI) https://nbn-resolving.org/urn:nbn:de:bsz:291--ds-416792 Show more show less Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Saarbrücken, 2023 Rüdesheim, Simeon; Selzer, Dominik; Fuhr, Uwe; Schwab, Matthias; Lehr, Thorsten Physiologically‐based pharmacokinetic modeling of dextromethorphan to investigate interindividual variability within CYP2D6 activity score groups Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Wiley, 2022 Published in: CPT: Pharmacometrics & Systems Pharmacology Rüdesheim, Simeon; Selzer, Dominik; Mürdter, Thomas; Igel, Svitlana; Kerb, Reinhold; Schwab, Matthias; Lehr, Thorsten Physiologically Based Pharmacokinetic Modeling to Describe the CYP2D6 Activity Score-Dependent Metabolism of Paroxetine, Atomoxetine and Risperidone Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. MDPI AG, 2022 Published in: Pharmaceutics Rüdesheim, Simeon; Wojtyniak, Jan-Georg; Selzer, Dominik; Hanke, Nina; Mahfoud, Felix; Schwab, Matthias; Lehr, Thorsten Physiologically Based Pharmacokinetic Modeling of Metoprolol Enantiomers and α-Hydroxymetoprolol to Describe CYP2D6 Drug-Gene Interactions Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. MDPI AG, 2020 Published in: Pharmaceutics Loer, Helena Leonie Hanae; Kovar, Christina; Rüdesheim, Simeon; Marok, Fatima Zahra; Fuhr, Laura Maria; Selzer, Dominik; Schwab, Matthias; Lehr, Thorsten Physiologically based pharmacokinetic modeling of imatinib and N‐desmethyl imatinib for drug–drug interaction predictions Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Wiley, 2024 Published in: CPT: Pharmacometrics & Systems Pharmacology Kovar, Christina; Kovar, Lukas; Rüdesheim, Simeon; Selzer, Dominik; Ganchev, Boian; Kröner, Patrick; Igel, Svitlana; Kerb, Reinhold; Schaeffeler, Elke; Mürdter, Thomas E.; Schwab, Matthias; Lehr, Thorsten Prediction of Drug–Drug–Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. MDPI AG, 2022 Published in: Pharmaceutics Loer, Helena Leonie Hanae; Feick, Denise; Rüdesheim, Simeon; Selzer, Dominik; Schwab, Matthias; Teutonico, Donato; Frechen, Sebastian; van der Lee, Maaike; Moes, Dirk Jan A. R.; Swen, Jesse J.; Lehr, Thorsten Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Wiley, 2023 Published in: CPT: Pharmacometrics & Systems Pharmacology Feick, Denise; Rüdesheim, Simeon; Marok, Fatima Zahra; Selzer, Dominik; Loer, Helena Leonie Hanae; Teutonico, Donato; Frechen, Sebastian; van der Lee, Maaike; Moes, Dirk Jan A. R.; Swen, Jesse J.; Schwab, Matthias; Lehr, Thorsten Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Wiley, 2023 Published in: CPT: Pharmacometrics & Systems Pharmacology
Rüdesheim, Simeon Matthias [Author] ; Lehr, Thorsten [Degree supervisor] Predicting the effect of drug-gene and drug-drug-gene interactions on the pharmacokinetics of CYP2D6 substrates : leveraging the activity score system in physiologically based pharmacokinetic modeling Books View online Schließen > Access https://d-nb.info/132252954X/34 kostenfrei Show more show less Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Saarbrücken: Saarländische Universitäts- und Landesbibliothek, 2023
Rüdesheim, Simeon Matthias [Author] ; Lehr, Thorsten [Degree supervisor]; Meyer, Markus Robert [Degree supervisor]; Schwab, Matthias [Degree supervisor] Predicting the effect of drug-gene and drug-drug-gene interactions on the pharmacokinetics of CYP2D6 substrates : leveraging the activity score system in physiologically based pharmacokinetic modeling Books View online Schließen > Access Full access (via DOI) https://nbn-resolving.org/urn:nbn:de:bsz:291--ds-416792 Show more show less Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Saarbrücken, 2023
> Access Full access (via DOI) https://nbn-resolving.org/urn:nbn:de:bsz:291--ds-416792 Show more show less
Rüdesheim, Simeon; Selzer, Dominik; Fuhr, Uwe; Schwab, Matthias; Lehr, Thorsten Physiologically‐based pharmacokinetic modeling of dextromethorphan to investigate interindividual variability within CYP2D6 activity score groups Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Wiley, 2022 Published in: CPT: Pharmacometrics & Systems Pharmacology
Rüdesheim, Simeon; Selzer, Dominik; Mürdter, Thomas; Igel, Svitlana; Kerb, Reinhold; Schwab, Matthias; Lehr, Thorsten Physiologically Based Pharmacokinetic Modeling to Describe the CYP2D6 Activity Score-Dependent Metabolism of Paroxetine, Atomoxetine and Risperidone Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. MDPI AG, 2022 Published in: Pharmaceutics
Rüdesheim, Simeon; Wojtyniak, Jan-Georg; Selzer, Dominik; Hanke, Nina; Mahfoud, Felix; Schwab, Matthias; Lehr, Thorsten Physiologically Based Pharmacokinetic Modeling of Metoprolol Enantiomers and α-Hydroxymetoprolol to Describe CYP2D6 Drug-Gene Interactions Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. MDPI AG, 2020 Published in: Pharmaceutics
Loer, Helena Leonie Hanae; Kovar, Christina; Rüdesheim, Simeon; Marok, Fatima Zahra; Fuhr, Laura Maria; Selzer, Dominik; Schwab, Matthias; Lehr, Thorsten Physiologically based pharmacokinetic modeling of imatinib and N‐desmethyl imatinib for drug–drug interaction predictions Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Wiley, 2024 Published in: CPT: Pharmacometrics & Systems Pharmacology
Kovar, Christina; Kovar, Lukas; Rüdesheim, Simeon; Selzer, Dominik; Ganchev, Boian; Kröner, Patrick; Igel, Svitlana; Kerb, Reinhold; Schaeffeler, Elke; Mürdter, Thomas E.; Schwab, Matthias; Lehr, Thorsten Prediction of Drug–Drug–Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. MDPI AG, 2022 Published in: Pharmaceutics
Loer, Helena Leonie Hanae; Feick, Denise; Rüdesheim, Simeon; Selzer, Dominik; Schwab, Matthias; Teutonico, Donato; Frechen, Sebastian; van der Lee, Maaike; Moes, Dirk Jan A. R.; Swen, Jesse J.; Lehr, Thorsten Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Wiley, 2023 Published in: CPT: Pharmacometrics & Systems Pharmacology
Feick, Denise; Rüdesheim, Simeon; Marok, Fatima Zahra; Selzer, Dominik; Loer, Helena Leonie Hanae; Teutonico, Donato; Frechen, Sebastian; van der Lee, Maaike; Moes, Dirk Jan A. R.; Swen, Jesse J.; Schwab, Matthias; Lehr, Thorsten Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network Articles View online Schließen > Access Close > Bookmarks You can manage bookmarks using lists, please log in to your user account for this. Wiley, 2023 Published in: CPT: Pharmacometrics & Systems Pharmacology
> Media type Skip to next facet Articles (7) Wert ausschließen Books (2) Wert ausschließen Show more show less
> Subject Skip to next facet Chemistry and pharmacology (3) Wert ausschließen Medicine (2) Wert ausschließen General sciences (1) Wert ausschließen Technology (1) Wert ausschließen Show more show less
> Creator Skip to next facet Lehr, Thorsten (9) Wert ausschließen Schwab, Matthias (8) Wert ausschließen Rüdesheim, Simeon (7) Wert ausschließen Selzer, Dominik (7) Wert ausschließen Loer, Helena Leonie Hanae (3) Wert ausschließen Feick, Denise (2) Wert ausschließen Frechen, Sebastian (2) Wert ausschließen Igel, Svitlana (2) Wert ausschließen Kerb, Reinhold (2) Wert ausschließen Kovar, Christina (2) Wert ausschließen Marok, Fatima Zahra (2) Wert ausschließen Moes, Dirk Jan A. R. (2) Wert ausschließen Swen, Jesse J. (2) Wert ausschließen Teutonico, Donato (2) Wert ausschließen van der Lee, Maaike (2) Wert ausschließen Fuhr, Laura Maria (1) Wert ausschließen Fuhr, Uwe (1) Wert ausschließen Ganchev, Boian (1) Wert ausschließen Hanke, Nina (1) Wert ausschließen Kovar, Lukas (1) Wert ausschließen Kröner, Patrick (1) Wert ausschließen Mahfoud, Felix (1) Wert ausschließen Meyer, Markus Robert (1) Wert ausschließen Mürdter, Thomas (1) Wert ausschließen Mürdter, Thomas E. (1) Wert ausschließen Rüdesheim, Simeon Matthias (1) Wert ausschließen Rüdesheim, Simeon Matthias (1) Wert ausschließen Schaeffeler, Elke (1) Wert ausschließen Wojtyniak, Jan-Georg (1) Wert ausschließen Show more show less
> Collection Skip to next facet Wiley (CrossRef) (4) Wert ausschließen MDPI AG (CrossRef) (3) Wert ausschließen Diss online (1) Wert ausschließen Lizenzfreie Online-Ressourcen (1) Wert ausschließen Verbunddaten SWB (1) Wert ausschließen Show more show less