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  8. De Santo, Carmela; Booth, Sarah; Vardon, Ashley; Cousins, Antony; Tubb, Vanessa; Perry, Tracey; Noyvert, Boris; Beggs, Andrew; Ng, Margaret; Halsey, Christina; Kearns, Pamela; Cheng, Paul; Mussai, Francis

    The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated‐recombinant arginase I BCT‐100

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    Wiley, 2018

    Published in: International Journal of Cancer

  10. Zhao, Weihua; Beers, David R.; Hooten, Kristopher G.; Sieglaff, Douglas H.; Zhang, Aijun; Kalyana-Sundaram, Shanker; Traini, Christopher M.; Halsey, Wendy S.; Hughes, Ashley M.; Sathe, Ganesh M.; Livi, George P.; Fan, Guo-Huang; Appel, Stanley H.

    Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes

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    American Medical Association (AMA), 2017

    Published in: JAMA Neurology

  11. Degenhardt, Yan; Greshock, Joel; Laquerre, Sylvie; Gilmartin, Aidan G.; Jing, Junping; Richter, Mark; Zhang, Xiping; Bleam, Maureen; Halsey, Wendy; Hughes, Ashley; Moy, Christopher; Liu-Sullivan, Nancy; Powers, Scott; Bachman, Kurtis; Jackson, Jeffrey; Weber, Barbara; Wooster, Richard

    Sensitivity of Cancer Cells to Plk1 Inhibitor GSK461364A Is Associated with Loss of p53 Function and Chromosome Instability

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    American Association for Cancer Research (AACR), 2010

    Published in: Molecular Cancer Therapeutics

  12. Smitheman, Kimberly N.; Severson, Tesa M.; Rajapurkar, Satyajit R.; McCabe, Michael T.; Karpinich, Natalie; Foley, James; Pappalardi, Melissa B.; Hughes, Ashley; Halsey, Wendy; Thomas, Elizabeth; Traini, Christopher; Federowicz, Kelly E.; Laraio, Jenny; Mobegi, Fredrick; Ferron-Brady, Geraldine; Prinjha, Rabinder K.; Carpenter, Christopher L.; Kruger, Ryan G.; Wessels, Lodewyk; Mohammad, Helai P.

    Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes

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    Ferrata Storti Foundation (Haematologica), 2019

    Published in: Haematologica

  13. Li, Xiangyi; Baek, GuemHee; Ramanand, Susmita G.; Sharp, Adam; Gao, Yunpeng; Yuan, Wei; Welti, Jon; Rodrigues, Daniel N.; Dolling, David; Figueiredo, Ines; Sumanasuriya, Semini; Crespo, Mateus; Aslam, Adam; Li, Rui; Yin, Yi; Mukherjee, Bipasha; Kanchwala, Mohammed; Hughes, Ashley M.; Halsey, Wendy S.; Chiang, Cheng-Ming; Xing, Chao; Raj, Ganesh V.; Burma, Sandeep; de Bono, Johann;

    BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer

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    Elsevier BV, 2018

    Published in: Cell Reports

  14. Welti, Jonathan; Sharp, Adam; Yuan, Wei; Dolling, David; Nava Rodrigues, Daniel; Figueiredo, Ines; Gil, Veronica; Neeb, Antje; Clarke, Matthew; Seed, George; Crespo, Mateus; Sumanasuriya, Semini; Ning, Jian; Knight, Eleanor; Francis, Jeffrey C.; Hughes, Ashley; Halsey, Wendy S.; Paschalis, Alec; Mani, Ram S.; Raj, Ganesh V.; Plymate, Stephen R.; Carreira, Suzanne; Boysen, Gunther; Chinnaiyan, Arul M.; [...]

    Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC)

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    American Association for Cancer Research (AACR), 2018

    Published in: Clinical Cancer Research

  15. Yu, Jong W.; Bhattacharya, Sabyasachi; Yanamandra, Niranjan; Kilian, David; Shi, Hong; Yadavilli, Sapna; Katlinskaya, Yuliya; Kaczynski, Heather; Conner, Michael; Benson, William; Hahn, Ashleigh; Seestaller-Wehr, Laura; Bi, Meixia; Vitali, Nicholas J.; Tsvetkov, Lyuben; Halsey, Wendy; Hughes, Ashley; Traini, Christopher; Zhou, Hui; Jing, Junping; Lee, Tae; Figueroa, David J.; Brett, Sara; Hopson, Christopher B.; [...]

    Tumor-immune profiling of murine syngeneic tumor models as a framework to guide mechanistic studies and predict therapy response in distinct tumor microenvironments

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    Public Library of Science (PLoS), 2018

    Published in: PLOS ONE

  16. Ott, Heidi M.; Graves, Alan P.; Pappalardi, Melissa B.; Huddleston, Michael; Halsey, Wendy S.; Hughes, Ashley M.; Groy, Arthur; Dul, Edward; Jiang, Yong; Bai, Yuchen; Annan, Roland; Verma, Sharad K.; Knight, Steven D.; Kruger, Ryan G.; Dhanak, Dashyant; Schwartz, Benjamin; Tummino, Peter J.; Creasy, Caretha L.; McCabe, Michael T.

    A687V EZH2 Is a Driver of Histone H3 Lysine 27 (H3K27) Hypertrimethylation

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    American Association for Cancer Research (AACR), 2014

    Published in: Molecular Cancer Therapeutics

  17. McCabe, Michael T.; Graves, Alan P.; Ganji, Gopinath; Ott, Heidi; Diaz, Elsie; Halsey, Wendy S.; Jiang, Yong; Smitheman, Kimberly N.; Pappalardi, Melissa B.; Allen, Kimberly E.; Chen, Stephanie; Della-Pietra, Anthony; Dul, Edward; Hughes, Ashley M.; Thrall, Sara H.; Tummino, Peter J.; Kruger, Ryan G.; Brandt, Martin; Schwartz, Benjamin; Verma, Sharad K.; Creasy, Caretha L.

    Abstract 1057: Mutation of EZH2 A677 in human B-cell lymphoma promotes hyper-trimethylation of H3K27

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    American Association for Cancer Research (AACR), 2012

    Published in: Cancer Research

  18. McCabe, Michael T.; Graves, Alan P.; Ganji, Gopinath; Diaz, Elsie; Halsey, Wendy S.; Jiang, Yong; Smitheman, Kimberly N.; Ott, Heidi M.; Pappalardi, Melissa B.; Allen, Kimberly E.; Chen, Stephanie B.; Della Pietra, Anthony; Dul, Edward; Hughes, Ashley M.; Gilbert, Seth A.; Thrall, Sara H.; Tummino, Peter J.; Kruger, Ryan G.; Brandt, Martin; Schwartz, Benjamin; Creasy, Caretha L.

    Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

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    Proceedings of the National Academy of Sciences, 2012

    Published in: Proceedings of the National Academy of Sciences

  19. McCabe, Michael T.; Graves, Alan P.; Ganji, Gopinath; Diaz, Elsie; Halsey, Wendy S.; Jiang, Yong; Smitheman, Kimberly N.; Ott, Heidi M.; Pappalardi, Melissa B.; Allen, Kimberly E.; Chen, Stephanie B.; Pietra, Anthony Della; Dul, Edward; Hughes, Ashley M.; Gilbert, Seth A.; Thrall, Sara H.; Tummino, Peter J.; Kruger, Ryan G.; Brandt, Martin; Schwartz, Benjamin; Creasy, Caretha L.

    Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

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    National Academy of Sciences, 2012

    Published in: Proceedings of the National Academy of Sciences of the United States of America

  20. Qin, Pu; Arabacilar, Pelin; Bernard, Roberta E.; Bao, Weike; Olzinski, Alan R.; Guo, Yuanjun; Lal, Hind; Eisennagel, Stephen H.; Platchek, Michael C.; Xie, Wensheng; del Rosario, Julius; Nayal, Mohamad; Lu, Quinn; Roethke, Theresa; Schnackenberg, Christine G.; Wright, Fe; Quaile, Michael P.; Halsey, Wendy S.; Hughes, Ashley M.; Sathe, Ganesh M.; Livi, George P.; Kirkpatrick, Robert B.; Qu, Xiaoyan A.; Rajpal, Deepak K.; [...]

    Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

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    Ovid Technologies (Wolters Kluwer Health), 2017

    Published in: Journal of the American Heart Association