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Thiele, Wilko [Author]; Rothley, Melanie [Author]; Kuch, Vanessa [Author]; Quagliata, Luca [Author]; Sleeman, Jonathan P. [Author]

VEGFR-3 is expressed on megakaryocyte precursors in the murine bone marrow and plays a regulatory role in megakaryopoiesis

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July 13, 2012

Published in: Blood ; 120(2012), 9, Seite 1899-1907
Nwosu, Zeribe C. [Author]; Rothley, Melanie [Author]; Piorońska, Weronika [Author]; Ebert, Matthias [Author]; Sleeman, Jonathan P. [Author]; Wölfl, Stefan [Author]; Meyer, Christoph [Author]; Dooley, Steven [Author]

Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours

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3 September 2018

Published in: Journal of experimental & clinical cancer research ; 37(2018) Artikel-Nummer 211, 15 Seiten
Nwosu, Zeribe C. [Author]; Rothley, Melanie [Author]; Piorońska, Weronika [Author]; Ebert, Matthias [Author]; Sleeman, Jonathan P. [Author]; Wölfl, Stefan [Author]; Meyer, Christoph [Author]; Dooley, Steven [Author]

Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours

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London: BioMed Central, 25 Okt. 2018 ; Heidelberg: Universitätsbibliothek Heidelberg, 25 Okt. 2018
Kyjacova, Lenka [Author]; Saup, Rafael [Author]; Rönsch, Kerstin [Author]; Wallbaum, Sabine [Author]; Dukowic-Schulze, Stefanie [Author]; Foss, Amelia [Author]; Scherer, Sandra [Author]; Rothley, Melanie [Author]; Neeb, Antje [Author]; Grau, Nicole [Author]; Thiele, Wilko [Author]; Thaler, Sonja [Author]; Cremers, Natascha [Author]; Sticht, Carsten [Author]; Gretz, Norbert [Author]; Garvalov, Boyan K. [Author]; Utikal, Jochen [Author]; Sleeman, Jonathan P. [Author]

IER2-induced senescence drives melanoma invasion through osteopontin

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https://www.nature.com/articles/s41388-021-02027-6

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05 October 2021

Published in: Oncogene ; 40(2021), 47, Seite 6494–6512
Sedlmeier, Georg [Author]; Al-Rawi, Vanessa [Author]; Buchert, Justyna [Author]; Yserentant, Klaus [Author]; Rothley, Melanie [Author]; Steshina, Anastasia [Author]; Gräßle, Simone [Author]; Wu, Ruolin [Author]; Hurrle, Thomas [Author]; Richer, Wilfrid [Author]; Decraene, Charles [Author]; Thiele, Wilko [Author]; Utikal, Jochen [Author]; Abuillan, Wasim [Author]; Tanaka, Motomu [Author]; Herten, Dirk-Peter [Author]; Hill, Caroline S. [Author]; Garvalov, Boyan K. [Author]; Jung, Nicole [Author]; Bräse, Stefan [Author]; Sleeman, Jonathan P. [Author]

Id1 and Id3 are regulated through matrix-assisted autocrine BMP signaling and represent therapeutic targets in melanoma

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https://onlinelibrary.wiley.com/doi/10.1002/adtp.202000065

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2021

Published in: Advanced therapeutics ; 4(2021), 2, Artikel-ID 2000065, Seite 1-17
Thiele, Wilko; Rothley, Melanie; Dimmler, Arno; Bugert, Peter; Salomó Coll, Carla; Sleeman, Jonathan P.

Platelet deficiency in Tpo−/− mice can both promote and suppress the metastasis of experimental breast tumors in an organ-specific manner

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Springer Science and Business Media LLC, 2018

Published in: Clinical & Experimental Metastasis
Kyjacova, Lenka; Saup, Rafael; Rothley, Melanie; Schmaus, Anja; Wagner, Tabea; Boßerhoff, Anja; Garvalov, Boyan K.; Thiele, Wilko; Sleeman, Jonathan P.

Quantitative Detection of Disseminated Melanoma Cells by Trp-1 Transcript Analysis Reveals Stochastic Distribution of Pulmonary Metastases

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MDPI AG, 2021

Published in: Journal of Clinical Medicine
Cremers, Natascha; Neeb, Antje; Uhle, Tanja; Dimmler, Arno; Rothley, Melanie; Allgayer, Heike; Fodde, Riccardo; Sleeman, Jonathan Paul; Thiele, Wilko

CD24 Is Not Required for Tumor Initiation and Growth in Murine Breast and Prostate Cancer Models

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Public Library of Science (PLoS), 2016

Published in: PLOS ONE
Thiele, Wilko; Krishnan, Jaya; Rothley, Melanie; Weih, Debra; Plaumann, Diana; Kuch, Vanessa; Quagliata, Luca; Weich, Herbert A.; Sleeman, Jonathan P.

VEGFR-3 is expressed on megakaryocyte precursors in the murine bone marrow and plays a regulatory role in megakaryopoiesis

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American Society of Hematology, 2012

Published in: Blood
Grau, Nicole; Scherer, Sandra D.; Rothley, Melanie; Roßwag, Sven; Thiele, Wilko; Stoecklein, Nikolas H.; Cremers, Natascha; Thaler, Sonja; Garvalov, Boyan K.; Sleeman, Jonathan P.

Spatiotemporally controlled induction of gene expression in vivo allows tracking the fate of tumor cells that traffic through the lymphatics

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Wiley, 2020

Published in: International Journal of Cancer
Schreiber, Caroline; Saraswati, Supriya; Harkins, Shannon; Gruber, Annette; Cremers, Natascha; Thiele, Wilko; Rothley, Melanie; Plaumann, Diana; Korn, Claudia; Armant, Olivier; Augustin, Hellmut G.; Sleeman, Jonathan P.

Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling

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Public Library of Science (PLoS), 2019

Published in: PLOS Genetics
Nwosu, Zeribe C.; Battello, Nadia; Rothley, Melanie; Piorońska, Weronika; Sitek, Barbara; Ebert, Matthias P.; Hofmann, Ute; Sleeman, Jonathan; Wölfl, Stefan; Meyer, Christoph; Megger, Dominik A.; Dooley, Steven

Correction to: Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours

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Springer Science and Business Media LLC, 2018

Published in: Journal of Experimental & Clinical Cancer Research
Nwosu, Zeribe C.; Battello, Nadia; Rothley, Melanie; Piorońska, Weronika; Sitek, Barbara; Ebert, Matthias P.; Hofmann, Ute; Sleeman, Jonathan; Wölfl, Stefan; Meyer, Christoph; Megger, Dominik A.; Dooley, Steven

Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours

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Springer Science and Business Media LLC, 2018

Published in: Journal of Experimental & Clinical Cancer Research
Quero, Lilian; Klawitter, Marina; Schmaus, Anja; Rothley, Melanie; Sleeman, Jonathan; Tiaden, André N; Klasen, Juergen; Boos, Norbert; Hottiger, Michael O; Wuertz, Karin; Richards, Peter J

Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways

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Springer Science and Business Media LLC, 2013

Published in: Arthritis Research & Therapy
Rothley, Melanie; Schmid, Anja; Thiele, Wilko; Schacht, Vivien; Plaumann, Diana; Gartner, Michael; Yektaoglu, Aybike; Bruyère, Françoise; Noël, Agnès; Giannis, Athanassios; Sleeman, Jonathan P.

Hyperforin and aristoforin inhibit lymphatic endothelial cell proliferation in vitro and suppress tumor‐induced lymphangiogenesis in vivo

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Wiley, 2009

Published in: International Journal of Cancer
Kyjacova, Lenka; Saup, Rafael; Rönsch, Kerstin; Wallbaum, Sabine; Dukowic-Schulze, Stefanie; Foss, Amelia; Scherer, Sandra D.; Rothley, Melanie; Neeb, Antje; Grau, Nicole; Thiele, Wilko; Thaler, Sonja; Cremers, Natascha; Sticht, Carsten; Gretz, Norbert; Garvalov, Boyan K.; Utikal, Jochen; Sleeman, Jonathan P.

IER2-induced senescence drives melanoma invasion through osteopontin

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Springer Science and Business Media LLC, 2021

Published in: Oncogene
Bauer, Jochen; Rothley, Melanie; Schmaus, Anja; Quagliata, Luca; Ehret, Markus; Biskup, Moritz; Orian-Rousseau, Véronique; Jackson, David G.; Pettis, Ronald J.; Harvey, Alfred; Bräse, Stefan; Thiele, Wilko; Sleeman, Jonathan P.

TGFβ counteracts LYVE-1-mediated induction of lymphangiogenesis by small hyaluronan oligosaccharides

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Springer Science and Business Media LLC, 2018

Published in: Journal of Molecular Medicine
Mudduluru, Giridhar; Abba, Mohammed; Batliner, Jasmin; Patil, Nitin; Scharp, Maike; Lunavat, Taral R.; Leupold, Jörg Hendrik; Oleksiuk, Olga; Juraeva, Dilafruz; Thiele, Wilko; Rothley, Melanie; Benner, Axel; Ben-Neriah, Yinon; Sleeman, Jonathan; Allgayer, Heike

A Systematic Approach to Defining the microRNA Landscape in Metastasis

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American Association for Cancer Research (AACR), 2015

Published in: Cancer Research
Mudduluru, Giridhar; Abba, Mohammed; Batliner, Jasmin; Patil, Nitin; Lunavat, Taral R.; Scharp, Maike; Leupold, Jörg; Oleksiuk, Olga; Buchhalter, Ivo; Thiele, Wilko; Rothley, Melanie; Benner, Axel; Sleeman, Jonathan; Allgayer, Heike

Abstract 1443: A systematic approach to the metastatically relevant microRNA landscape

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American Association for Cancer Research (AACR), 2014

Published in: Cancer Research
Thiele, Wilko; Rothley, Melanie; Teller, Nicole; Jung, Nicole; Bulat, Bekir; Plaumann, Diana; Vanderheiden, Sylvia; Schmaus, Anja; Cremers, Natascha; Göppert, Bettina; Dimmler, Arno; Eschbach, Verena; Quagliata, Luca; Thaler, Sonja; Marko, Doris; Bräse, Stefan; Sleeman, Jonathan P.

Delphinidin is a novel inhibitor of lymphangiogenesis but promotes mammary tumor growth and metastasis formation in syngeneic experimental rats

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Oxford University Press (OUP), 2013

Published in: Carcinogenesis

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