• Media type: E-Book
  • Title: Introduction to Basics of Pharmacology and Toxicology : Volume 1: General and Molecular Pharmacology: Principles of Drug Action
  • Contributor: Raj, Gerard Marshall [HerausgeberIn]; Raveendran, Ramasamy [HerausgeberIn]
  • Published: Singapore: Springer, 2019
  • Published in: Springer eBooks ; Biomedical and Life Sciences
    Springer eBook Collection
  • Issue: 1st ed. 2019
  • Extent: 1 Online-Ressource (XVIII, 417 p. 87 illus., 39 illus. in color)
  • Language: English
  • ISBN: 9789813297791
  • DOI: 10.1007/978-981-32-9779-1
  • Identifier:
  • Origination:
  • Keywords: Pharmaceutical Sciences/Technology ; Pharmaceutical technology ; Pharmacy ; Drug resistance ; Pharmacological Phenomena
  • Description: Part 1. Historical Aspects of Drug Discovery -- Chapter 1. The Great Pharmacologists and Their Revolutionary Discoveries. Chapter 2. Indian Contributions to Pharmacology -- Part 2. General Pharmacological Principles -- Chapter 3. Sources and Nature of Drugs. Chapter 4. Principles and Modes of Drug Administration -- Chapter 5. Drug Absorption and Bioavailability -- Chapter 6. Drug Distribution -- Chapter 7. Drug Metabolism -- Chapter 8. Drug Elimination -- Chapter 9. Mechanisms of Drug Action -- Chapter 10. Drug Transporters -- Chapter 11. Adverse Effects and Pharmacovigilance -- Chapter 12. Drug Interactions -- Chapter 13. Structure-Activity Relationships -- Part 3. Special Topics in Pharmacology -- Chapter 14. Drug Information -- Chapter 15. Pharmacogenetics, Pharmacogenomics and Personalized Medicine -- Chapter 16. Chronopharmacology -- Chapter 17. Pharmacoepidemiology -- Chapter 18. Ethnopharmacology -- Chapter 19. Pharmacoeconomics -- Chapter 20. Orphan Diseases and Drugs -- Chapter 21. Fixed-Dose Combinations. Chapter 22. Translational and Reverse Pharmacology -- Chapter 23. Gene Therapy -- Chapter 24. Stem Cell Therapy -- Chapter 25. Principles of Prescription Writing -- Part 4. Toxicology -- Chapter 26. Environmental Toxicology -- Chapter 27. Basic Principles of Management of Drug Poisoning -- Part 5. Molecular Biology in Pharmacology -- Chapter 28. Regulation of Gene Expression -- Chapter 29. Proteomics -- Chapter 30. Techniques Involved in Studying Receptor Dynamics -- Chapter 31. Polymerase Chain Reaction -- Chapter 32. Southern, Western and Northern Blotting -- Chapter 33. Antisense Oligonucleotides -- Chapter 34. Recombinant DNA Technology

    This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology
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