Prognosis and management of acute symptomatic seizures: a prospective, multicenter, observational study

Media type: E-Article

Title: Prognosis and management of acute symptomatic seizures : a prospective, multicenter, observational study

Contributor: Herzig-Nichtweiß, Julia [Author]; Salih, Farid [Author]; Berning, Sascha [Author]; Malter, Michael P. [Author]; Pelz, Johann O. [Author]; Lochner, Piergiorgio [Author]; Wittstock, Matthias [Author]; Günther, Albrecht [Author]; Alonso, Angelika [Author]; Fuhrer, Hannah [Author]; Schönenberger, Silvia [Author]; Petersen, Martina [Author]; Kohle, Felix [Author]; Müller, Annekatrin [Author]; Gawlitza, Alexander [Author]; Gubarev, Waldemar [Author]; Holtkamp, Martin [Author]; Vorderwülbecke, Bernd J. [Author]

Published: 2023

Language: English

DOI: 10.1186/s13613-023-01183-0

Identifier:

Keywords: Acute symptomatic seizure ; Antiseizure medication ; Cerebrovascular accident ; CNS infection ; Ischemic stroke ; Mortality ; Secondary seizure prophylaxis ; Seizure risk ; Structural brain damage ; Unprovoked seizure

Origination:

Footnote: Veröffentlicht: 15. September 2023

Description: Acute symptomatic epileptic seizures are frequently seen in neurocritical care. To prevent subsequent unprovoked seizures, long-term treatments with antiseizure medications are often initiated although supporting evidence is lacking. This study aimed at prospectively assessing the risk of unprovoked seizure relapse with respect to the use of antiseizure medications. It was hypothesized that after a first acute symptomatic seizure of structural etiology, the cumulative 12-month risk of unprovoked seizure relapse is ≤ 25%.

Access State: Open Access

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