Contains:
Target family-directed masterkeyes in chemogenomics / Gehard Müller
Drug discovery from side effects / Hugo Kubinyi
The value of chemical genetics in drug discovery / Keith Russell and William F. Michne
Structural aspects of binding site similarity: a 3D upgrade for chemogenomics / Andreas Bergner and Judith Günther
The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds / Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin
Chemical kinomics / Bert M. Klebl, Henrik Daub, and György Kéri
Structural aspects of kinases and their inhibitors / Rogier Buijsman
A chemical genomics approach for ion channel modulators / Karl-Heinz Baringhaus and Gerhard Hessler
Phosphodiesterase inhibitors: a chemogenomic view / Martin Hendrix and Christopher Kallus
Proteochemometrics: a tool for modeling the molecular interaction space / Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis
Some principles related to chemogenomics in compound library and template design for GPCRs / Thomas R. Webb
Computational filters in lead generation: targeting drug-like chemotypes / Wolfgang Guba and Olivier Roche
Navigation in chemical space: ligand-based design of focused compound libraries / Gisbert Schneider and Petra Schneider
Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates / Marcus A. Koch and Herbert Waldmann
Combinatorial chemistry in the age of chemical genomics / Reni Joseph and Prabhat Arya.
Extent:
XXIV, 463 S; Ill., graph. Darst; 25 cm
Language:
English
ISBN:
352730987X
Publisher, production or purchase order numbers:
Sonstige Nummer: 1130987 000