Maeremans, Joren;
Verhaert, David;
Pereira, Bruno;
Frambach, Peter;
Van Mieghem, Carlos;
Barbato, Emanuele;
Willems, Endry;
Vrolix, Mathias;
Dens, Jo
One‐year clinical and computed tomography follow‐up after implantation of bioresorbable vascular scaffolds in patients with coronary chronic total occlusions
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Media type:
E-Article
Title:
One‐year clinical and computed tomography follow‐up after implantation of bioresorbable vascular scaffolds in patients with coronary chronic total occlusions
Contributor:
Maeremans, Joren;
Verhaert, David;
Pereira, Bruno;
Frambach, Peter;
Van Mieghem, Carlos;
Barbato, Emanuele;
Willems, Endry;
Vrolix, Mathias;
Dens, Jo
imprint:
Wiley, 2018
Published in:Catheterization and Cardiovascular Interventions
Description:
<jats:title>Abstract</jats:title><jats:sec><jats:title>Objectives</jats:title><jats:p>To assess the safety and efficacy of everolimus‐eluting bioresorbable scaffolds (BRS) in the treatment of chronic total occlusions (CTO) using noninvasive multislice computed tomography (MSCT) angiography at one‐year follow‐up.</jats:p></jats:sec><jats:sec><jats:title>Background</jats:title><jats:p>Current evidence regarding the safety and efficacy of BRS for the percutaneous treatment of CTO is limited.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Between September 2013 and January 2016, patients who received one or more ABSORB BRSs were included at three centers. MSCT (including quantitative analysis) and clinical follow‐up were performed at one year.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Forty‐one CTO patients were included. Mean age was 60 ± 11 years and the majority was male (83%). Average Japanese CTO (J‐CTO) score was 0.9 ± 0.9. Seventy‐one BRS were implanted in total with, on average, 1.7 ± 0.8 scaffolds/patient, and a total length of 43 ± 20 mm and diameter of 3.1 ± 0.4 mm. One noncardiac death took place. MSCT angiography was performed in 34 (83%) patients: all scaffolds were patent, except in one patient, in whom a patent target vessel was present on subsequent diagnostic angiography. MSCT quality was sufficient for quantitative analyses in 27 patients (46 scaffolds): median reference versus scaffold minimal lumen diameter and minimal lumen area were measured, and showed a small difference of 0.1 mm (−0.2–0.4) (lumen diameter stenosis = 3.0%) and 0.5 mm<jats:sup>2</jats:sup> (−1.0–2.0) (lumen area stenosis = 4.2%).</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>The low number of events and high patency rate at 1 year are encouraging the further use of the ABSORB scaffold for CTOs with low J‐CTO score. Noninvasive MSCT angiography is a valid tool to assess scaffold patency, although its image resolution limits the use for quantitative measurements.</jats:p></jats:sec>