• Media type: E-Article
  • Title: Type IX collagen is a potent inducer of PGE2 and interleukin 1 production by human monocyte macrophages
  • Contributor: Dayer, Jean-Michel; Ricard-Blum, Sylvie; Kaufmann, Marie-Thérèse; Herbage, Daniel
  • imprint: Wiley, 1986
  • Published in: FEBS Letters
  • Language: English
  • DOI: 10.1016/0014-5793(86)80406-9
  • ISSN: 0014-5793; 1873-3468
  • Keywords: Cell Biology ; Genetics ; Molecular Biology ; Biochemistry ; Structural Biology ; Biophysics
  • Origination:
  • Footnote:
  • Description: <jats:p>Type IX collagen and its collagenous fragments are potent stimulatory agents on human blood mononuclear cells for the production of prostaglandin E<jats:sub>2</jats:sub> and interleukin 1/mononuclear cell factor. Type IX collagen is 2–4‐fold more potent that type I and II and 1α‐, 2α‐ and 3α‐collagens. This property may be important in the destructive process of cartilage in inflammatory diseases.</jats:p>
  • Access State: Open Access