• Media type: E-Article
  • Title: Dopamine, Parkinson's disease, and volition
  • Contributor: Horvitz, Jon C.
  • Published: Cambridge University Press (CUP), 2002
  • Published in: Behavioral and Brain Sciences, 25 (2002) 5, Seite 586-586
  • Language: English
  • DOI: 10.1017/s0140525x02300104
  • ISSN: 0140-525X; 1469-1825
  • Origination:
  • Footnote:
  • Description: Disruptions in dopamine transmission within the basal ganglia (BG) produce deficits in voluntary actions, that is, in the interface between cortically-generated goal representation and BG-mediated response selection. Under conditions of dopamine loss in humans and other animals, responses are impaired when they require internal generation, but are relatively intact when elicited by external stimuli.