• Media type: E-Article
  • Title: Effect of N-1 arylation of monastrol on kinesin Eg5 inhibition in glioma cell lines
  • Contributor: Gonçalves, Itamar Luís; Rockenbach, Liliana; das Neves, Gustavo Machado; Göethel, Gabriela; Nascimento, Fabiana; Porto Kagami, Luciano; Figueiró, Fabrício; Oliveira de Azambuja, Gabriel; de Fraga Dias, Amanda; Amaro, Andressa; de Souza, Lauro Mera; da Rocha Pitta, Ivan; Avila, Daiana Silva; Kawano, Daniel Fábio; Garcia, Solange Cristina; Battastini, Ana Maria Oliveira; Eifler-Lima, Vera Lucia
  • Published: Royal Society of Chemistry (RSC), 2018
  • Published in: MedChemComm, 9 (2018) 6, Seite 995-1010
  • Language: English
  • DOI: 10.1039/c8md00095f
  • ISSN: 2040-2503; 2040-2511
  • Origination:
  • Footnote:
  • Description: An original and focused library of dihydropyrimidin-2-thiones N-1 aryl substituted derived from monastrol was designed and synthesized in order to discover a more effective Eg5 ligand.
  • Access State: Open Access