• Media type: E-Article
  • Title: Prevalence of Periodontitis among Patients Diagnosed with Marfan Syndrome: A Cross-Sectional Study Comparing Samples of Healthy Patients
  • Contributor: Galletti, Cosimo; Toledano-Serrabona, Jorge; Camps-Font, Octavi; Teixido-Tura, Gisela; Llobet-Poal, Inmaculada; Subirà-Pifarré, Carles; Fiorillo, Luca; Gay-Escoda, Cosme
  • Published in: BioMed Research International
  • Published: Hindawi Limited, 2022
  • Language: English
  • DOI: 10.1155/2022/6238099
  • ISSN: 2314-6133; 2314-6141
  • Keywords: General Immunology and Microbiology ; General Biochemistry, Genetics and Molecular Biology ; General Medicine
  • Abstract: <jats:p>Periodontitis is an inflammatory condition caused by a bacterial plaque and characterized by progressive destruction of the tooth-supporting apparatus. Patients with Marfan syndrome (MFS) exhibit a connective tissue disorder, which can also affect oral soft and hard tissue. Thus, the aims of this cross-sectional study were to assess the association between periodontitis and MFS and secondly, to compare periodontal parameters and prevalence of disease with a control group (CG) without MFS. 152 patients (<jats:inline-formula> <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <mtext>MFS</mtext> <mo>=</mo> <mn>76</mn> <mo>,</mo> <mtext>CG</mtext> <mo>=</mo> <mn>76</mn> </math> </jats:inline-formula>) were recruited to evaluate the following periodontal parameters: probing depth, gingival margin, clinical attachment level, plaque index, and bleeding on probing. The 2017 World Workshop guideline was followed for the diagnosis of the periodontal status. A multivariate analysis was performed using a multinomial logistic regression adjusted for age, gender, and smoking. The level of significance required was <jats:inline-formula> <math xmlns="http://www.w3.org/1998/Math/MathML" id="M2"> <mi>p</mi> <mo>&lt;</mo> <mn>0.05</mn> </math> </jats:inline-formula>. Patients with MFS did not show a higher prevalence of periodontitis compared to the CG. However, patients with MFS did have higher values in probing depth, gingival recession, clinical attachment level, and plaque index compared to the CG patients (<jats:inline-formula> <math xmlns="http://www.w3.org/1998/Math/MathML" id="M3"> <mi>p</mi> <mo>&lt;</mo> <mn>0.05</mn> </math> </jats:inline-formula>). In conclusion, although similar prevalence of periodontitis was found among the studied groups, MFS patients showed worse periodontal parameters.</jats:p>
  • Description: <jats:p>Periodontitis is an inflammatory condition caused by a bacterial plaque and characterized by progressive destruction of the tooth-supporting apparatus. Patients with Marfan syndrome (MFS) exhibit a connective tissue disorder, which can also affect oral soft and hard tissue. Thus, the aims of this cross-sectional study were to assess the association between periodontitis and MFS and secondly, to compare periodontal parameters and prevalence of disease with a control group (CG) without MFS. 152 patients (<jats:inline-formula>
    <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1">
    <mtext>MFS</mtext>
    <mo>=</mo>
    <mn>76</mn>
    <mo>,</mo>
    <mtext>CG</mtext>
    <mo>=</mo>
    <mn>76</mn>
    </math>
    </jats:inline-formula>) were recruited to evaluate the following periodontal parameters: probing depth, gingival margin, clinical attachment level, plaque index, and bleeding on probing. The 2017 World Workshop guideline was followed for the diagnosis of the periodontal status. A multivariate analysis was performed using a multinomial logistic regression adjusted for age, gender, and smoking. The level of significance required was <jats:inline-formula>
    <math xmlns="http://www.w3.org/1998/Math/MathML" id="M2">
    <mi>p</mi>
    <mo>&lt;</mo>
    <mn>0.05</mn>
    </math>
    </jats:inline-formula>. Patients with MFS did not show a higher prevalence of periodontitis compared to the CG. However, patients with MFS did have higher values in probing depth, gingival recession, clinical attachment level, and plaque index compared to the CG patients (<jats:inline-formula>
    <math xmlns="http://www.w3.org/1998/Math/MathML" id="M3">
    <mi>p</mi>
    <mo>&lt;</mo>
    <mn>0.05</mn>
    </math>
    </jats:inline-formula>). In conclusion, although similar prevalence of periodontitis was found among the studied groups, MFS patients showed worse periodontal parameters.</jats:p>
  • Footnote:
  • Access State: Open Access