• Media type: E-Article
  • Title: Learning From Errors: Response to Gefitinib in Kidney Urothelial Carcinoma With EGFR Mutations
  • Contributor: Fiorentino, Michelangelo; Giunchi, Francesca; Altimari, Annalisa; Di Tullio, PierGiorgio; Gruppioni, Elisa; Martorana, Giuseppe; Pinto, Carmine
  • Published: Oxford University Press (OUP), 2014
  • Published in: The Oncologist
  • Extent: 430-430
  • Language: English
  • DOI: 10.1634/theoncologist.2013-0346
  • ISSN: 1549-490X; 1083-7159
  • Keywords: Cancer Research ; Oncology
  • Abstract: <jats:p>This letter describes the first demonstration of clinical response to the anti-EGFR inhibitor gefitinib in a case of urothelial carcinoma of the renal pelvis harboring a rare EGFR double mutation. New mutations and unexpected clinical responses should be always explored through wide-spectrum mutational analyses.</jats:p>
  • Description: <jats:p>This letter describes the first demonstration of clinical response to the anti-EGFR inhibitor gefitinib in a case of urothelial carcinoma of the renal pelvis harboring a rare EGFR double mutation. New mutations and unexpected clinical responses should be always explored through wide-spectrum mutational analyses.</jats:p>
  • Footnote:
  • Access State: Open Access