• Media type: E-Article
  • Title: A Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure
  • Contributor: Kennel, Peter J.; Schulze, P. Christian
  • imprint: MDPI AG, 2021
  • Published in: Cells
  • Language: English
  • DOI: 10.3390/cells10113191
  • ISSN: 2073-4409
  • Keywords: General Medicine
  • Origination:
  • Footnote:
  • Description: <jats:p>MiRNA-regulated processes are pivotal in cardiovascular homeostasis and disease. These short non-coding RNAs have ideal properties that could be utilized as potential biomarkers; moreover, their functions as post-transcriptional regulators of mRNA make them interesting therapeutic targets. In this review, we summarize the current state of miRNA-based biomarkers in a variety of diseases leading to heart failure, as well as provide an outlook on developing miRNA-based therapies in the heart failure field.</jats:p>
  • Access State: Open Access